3,771 research outputs found

    An International Expert Delphi Consensus to Develop Dedicated Geriatric Radiation Oncology Curriculum Learning Outcomes.

    Full text link
    PURPOSE: The management of older adults with cancer is rapidly becoming a significant challenge in radiation oncology (RO) practice. The education of future radiation oncologists in geriatric oncology is fundamental to ensuring that older adults receive high-quality care. Currently RO trainees receive little training and education in geriatric oncology. The objective of this study was to define core geriatric RO curriculum learning outcomes relevant to RO trainees worldwide. METHODS AND MATERIALS: A 2-stage modified Delphi consensus was conducted. Stage 1 involved the formation of an expert reference panel (ERP) of multiprofessional experts in geriatric oncology and/or RO and the compilation of a potential geriatric RO learning outcomes set. Stage 2 involved 3 iterative rounds: round 1 and round 2 (both online surveys), and an intervening ERP round. These aimed at identifying and refining ideal geriatric RO learning outcomes. Invited participants for round 1 and 2 included oncology health care professionals with expertise across RO, geriatric oncology, and/or education and consumers. Predefined Delphi consensus definitions were applied to the results of rounds 1 and 2. RESULTS: An ERP of 11 experts in geriatric oncology and/or RO was formed. Seventy potential knowledge- and skill-based learning outcomes were identified. In round 1, 103 of 179 invited eligible Delphi participants completed the survey (58% response rate). The ERP round was conducted, resulting in the exclusion of 28 learning outcomes. In round 2, 54 of 103 completed the survey (52% response rate). This identified a final total of 33 geriatric RO learning outcomes. CONCLUSIONS: The geriatric RO learning outcomes described in this study form an international consensus that can inform RO training bodies worldwide. This represents the first fundamental step in developing a global educational framework aimed at improving RO trainee knowledge and skills in geriatric oncology

    Circumstellar molecular composition of the oxygen-rich AGB star IK Tau: I. Observations and LTE chemical abundance analysis

    Full text link
    The aim of this paper is to study the molecular composition in the circumstellar envelope around the oxygen-rich star IK Tau. We observed IK Tau in several (sub)millimeter bands using the APEX telescope during three observing periods. To determine the spatial distribution of the 12CO(32)\mathrm{^{12}CO(3-2)} emission, mapping observations were performed. To constrain the physical conditions in the circumstellar envelope, multiple rotational CO emission lines were modeled using a non local thermodynamic equilibrium radiative transfer code. The rotational temperatures and the abundances of the other molecules were obtained assuming local thermodynamic equilibrium. An oxygen-rich Asymptotic Giant Branch star has been surveyed in the submillimeter wavelength range. Thirty four transitions of twelve molecular species, including maser lines, were detected. The kinetic temperature of the envelope was determined and the molecular abundance fractions of the molecules were estimated. The deduced molecular abundances were compared with observations and modeling from the literature and agree within a factor of 10, except for SO2_2, which is found to be almost a factor 100 stronger than predicted by chemical models. From this study, we found that IK Tau is a good laboratory to study the conditions in circumstellar envelopes around oxygen-rich stars with (sub)millimeter-wavelength molecular lines. We could also expect from this study that the molecules in the circumstellar envelope can be explained more faithful by non-LTE analysis with lower and higher transition lines than by simple LTE analysis with only lower transition lines. In particular, the observed CO line profiles could be well reproduced by a simple expanding envelope model with a power law structure.Comment: 13 pages, 14 figures, 8 tables *Accepted for publication in Astronomy and Astrophysic

    Probing the isovector transition strength of the low-lying nuclear excitations induced by inverse kinematics proton scattering

    Full text link
    A compact approach based on the folding model is suggested for the determination of the isoscalar and isovector transition strengths of the low-lying (ΔS=ΔT=0\Delta S=\Delta T=0) excitations induced by inelastic proton scattering measured with exotic beams. Our analysis of the recently measured inelastic 18,20^{18,20}O+p scattering data at Elab=30E_{\rm lab}=30 and 43 MeV/nucleon has given for the first time an accurate estimate of the isoscalar β0\beta_0 and isovector β1\beta_1 deformation parameters (which cannot be determined from the (p,p') data alone by standard methods) for 21+^+_1 and 313^-_1 excited states in 18,20^{18,20}O. Quite strong isovector mixing was found in the 21+^+_1 inelastic 20^{20}O+p scattering channel, where the strength of the isovector form factor F1F_1 (prototype of the Lane potential) corresponds to a β1\beta_1 value almost 3 times larger than β0\beta_0 and a ratio of nuclear transition matrix elements Mn/Mp4.2M_n/M_p\simeq 4.2.Comment: 5 pages, 3 figure

    Beyond the COVID-19 Pandemic: Tips for Players and Athletes COVID-RECOVER

    Get PDF
    First paragraph: The aim of this guidance is to provide a framework for athletes to cope, thrive and engage in personal growth during the current pandemic. The COVID-19 pandemic has likely led to wide-scale disruption of your sporting trajectories for 2020. This has included the cancellation or postponement of sporting events, limits to group training due to social distancing, restrictions on use of sporting facilities and loss of face-to-face access to coaches and support personnel. In the context of a threat to public health, arguably sports competition sinks into lesser importance, but for athletes like you, for whom sport is a fulltime job or major life goal, or for those who identify sports competition as a key part of their identity, it is important to share recommendations based on evidence and theory on how to support athletes and players through this time. The unprecedented situation means that evidence from similar or related contexts and relevant theories needs to be used to extrapolate to COVID-19 and all its challenges. Each of the guidelines below should be viewed like a menu to choose from and try, test and review, and be seen as a road to discovery instead of passive prescription of activities. Our team of practitioners and researchers have collated the knowledge below based on four premises: 1. Psychological Strengths: As a performer on the sporting stage, you have, in all likelihood, developed many skills and habits to support your on-field performance. Pre-performance routines for penalty taking, for example, may include relaxation and focusing components which aid emotional regulation. This can be also applied to help you cope in world outside of sport (i.e. outside the bubble). Awareness of your repertoire of psychological skills and the ability to use them across different contexts is highly important. 2. Resilience: The capacity to mobilise resources both in advance and after a major challenge, is developed through our sporting challenges. In the face of a trauma, it is likely that resilience is the default rather than the exception. As an athlete, you have the ability to respond in an optimistic way to major stressors and engage in post-traumatic growth. Further, you have successful experiences from memory to call upon on which By doing this, you build a firm foundation on which to build your beliefs that you have sufficient resources to cope with COVID-19. 3. Individual Responses: It is important to acknowledge that athletes in different sports and at different levels of competition have developed diverse sets of abilities and competencies. Dual-career athletes (e.g. student-athletes) may have invested much of their effort in their sport despite study or work commitments, and injured athletes may be over-identifying with their sport as a predictable response to injury, in both cases making these athletes very vulnerable to major stressors. 4. Perception of Control: Loss of control is a major source of anxiety in a pandemic (see Mansell, 2020). Developing autonomy and a sense of control is a key part to feeling safe and secure. With COVID-19, the new habits that could help protect you such as physical isolation, hand hygiene, and avoiding touching your face can help you gain control in an uncertain world. And finding new ways to exercise, to work and to interact can open up a world of exciting possibilities. Athletes have shown an ability to develop positive habits and maintain self-control, skills transferable to meeting the present challenging circumstances

    The institutional shaping of management: in the tracks of English individualism

    Get PDF
    Globalisation raises important questions about the shaping of economic action by cultural factors. This article explores the formation of what is seen by some as a prime influence on the formation of British management: individualism. Drawing on a range of historical sources, it argues for a comparative approach. In this case, the primary comparison drawn is between England and Scotland. The contention is that there is a systemic approach to authority in Scotland that can be contrasted to a personal approach in England. An examination of the careers of a number of Scottish pioneers of management suggests the roots of this systemic approach in practices of church governance. Ultimately this systemic approach was to take a secondary role to the personal approach engendered by institutions like the universities of Oxford and Cambridge, but it found more success in the different institutional context of the USA. The complexities of dealing with historical evidence are stressed, as is the value of taking a comparative approach. In this case this indicates a need to take religious practice as seriously as religious belief as a source of transferable practice. The article suggests that management should not be seen as a simple response to economic imperatives, but as shaped by the social and cultural context from which it emerges

    Beyond the COVID-19 Pandemic: Tips for Players and Athletes COVID-RECOVER

    Get PDF
    First paragraph: The aim of this guidance is to provide a framework for athletes to cope, thrive and engage in personal growth during the current pandemic. The COVID-19 pandemic has likely led to wide-scale disruption of your sporting trajectories for 2020. This has included the cancellation or postponement of sporting events, limits to group training due to social distancing, restrictions on use of sporting facilities and loss of face-to-face access to coaches and support personnel. In the context of a threat to public health, arguably sports competition sinks into lesser importance, but for athletes like you, for whom sport is a fulltime job or major life goal, or for those who identify sports competition as a key part of their identity, it is important to share recommendations based on evidence and theory on how to support athletes and players through this time. The unprecedented situation means that evidence from similar or related contexts and relevant theories needs to be used to extrapolate to COVID-19 and all its challenges. Each of the guidelines below should be viewed like a menu to choose from and try, test and review, and be seen as a road to discovery instead of passive prescription of activities. Our team of practitioners and researchers have collated the knowledge below based on four premises: 1. Psychological Strengths: As a performer on the sporting stage, you have, in all likelihood, developed many skills and habits to support your on-field performance. Pre-performance routines for penalty taking, for example, may include relaxation and focusing components which aid emotional regulation. This can be also applied to help you cope in world outside of sport (i.e. outside the bubble). Awareness of your repertoire of psychological skills and the ability to use them across different contexts is highly important. 2. Resilience: The capacity to mobilise resources both in advance and after a major challenge, is developed through our sporting challenges. In the face of a trauma, it is likely that resilience is the default rather than the exception. As an athlete, you have the ability to respond in an optimistic way to major stressors and engage in post-traumatic growth. Further, you have successful experiences from memory to call upon on which By doing this, you build a firm foundation on which to build your beliefs that you have sufficient resources to cope with COVID-19. 3. Individual Responses: It is important to acknowledge that athletes in different sports and at different levels of competition have developed diverse sets of abilities and competencies. Dual-career athletes (e.g. student-athletes) may have invested much of their effort in their sport despite study or work commitments, and injured athletes may be over-identifying with their sport as a predictable response to injury, in both cases making these athletes very vulnerable to major stressors. 4. Perception of Control: Loss of control is a major source of anxiety in a pandemic (see Mansell, 2020). Developing autonomy and a sense of control is a key part to feeling safe and secure. With COVID-19, the new habits that could help protect you such as physical isolation, hand hygiene, and avoiding touching your face can help you gain control in an uncertain world. And finding new ways to exercise, to work and to interact can open up a world of exciting possibilities. Athletes have shown an ability to develop positive habits and maintain self-control, skills transferable to meeting the present challenging circumstances

    The Muon Anomalous Magnetic Moment: A Harbinger For "New Physics"

    Get PDF
    QED, Hadronic, and Electroweak Standard Model contributions to the muon anomalous magnetic moment, a_mu = (g_mu-2)/2, and their theoretical uncertainties are scrutinized. The status and implications of the recently reported 2.6 sigma experiment vs.theory deviation a_mu^{exp}-a_mu^{SM} = 426(165) times 10^{-11} are discussed. Possible explanations due to supersymmetric loop effects with m_{SUSY} \simeq 55 sqrt{tan beta} GeV, radiative mass mechanisms at the 1--2 TeV scale and other ``New Physics'' scenarios are examined.Comment: 24 page

    Biology of a new virus isolated from Lupinus nootkatensis plants in Alaska

    Get PDF
    A new virus named Nootka lupine vein-clearing virus (NLVCV) was isolated from Lupinus nootkatensis plants that were confined to a relatively small area in the Talkeetna mountains of south-central Alaska. Annual surveys (2000–03) consistently found leaf symptoms of pronounced vein clearing and mosaic on 3- to 4-week-old plants in late June. Spherical particles ≈ 30 nm in diameter were isolated from these leaves. Virions contained a single-stranded RNA of ≈ 4·0–4·2 kb and one species of capsid protein estimated to be ≈ 40 kDa. The double-stranded RNA profile from naturally infected leaves consisted of three major bands ≈ 4·2, 1·9 and 1·5 kbp. Protein extractions from either sap or virions of diseased plants reacted to polyclonal antiserum made against the virions in Western blot assays. A predicted PCR product ≈ 500 bp was synthesized from virion RNA using primers specific to the carmovirus RNA-dependent RNA polymerase (RDRP) gene. The nucleotide sequence of the amplified DNA did not match any known virus, but contained short regions of identity to several carmoviruses. Only species belonging to the Fabaceae were susceptible to NLVCV by mechanical inoculation. Based on dsRNA profile, size of virion RNA genome and capsid protein, and similarity of the RDRP gene to that of other carmoviruses, it is suggested that NLVCV is a member of the family Tombusviridae , and tentatively of the genus Carmovirus . As the host range, RDRP gene and dsRNA profile of NLVCV are different from those of known viruses, this is a newly described plant virus
    corecore