2,184 research outputs found
El clero francés en tiempos del Cura de Ars.
El presente artículo analiza la situación del
clero francés desde la salida de la Revolución francesa
y la firma del Concordato de 1801 hasta mitad de
siglo. Se estudia la recuperación de la Iglesia católica
en la Francia post-revolucionaria, haciendo hincapié
en las circunstancias que rodeaban la formación de
los futuros sacerdotes. Luego, se explica el estado de
las parroquias, para pasar a explicar los métodos de
transmisión de la fe y de santificación de la parroquia,
con la práctica sacramental. En un último punto, se
habla de la sociabilidad clerical y de la visión que tienen
los fieles del sacerdote, especialmente por parte de las
autoridades municipales
Ultracold collisions involving heteronuclear alkali metal dimers
We have carried out the first quantum dynamics calculations on ultracold
atom-diatom collisions in isotopic mixtures. The systems studied are
spin-polarized 7Li + 6Li7Li, 7Li + 6Li2, 6Li + 6Li7Li and 6Li + 7Li2. Reactive
scattering can occur for the first two systems even when the molecules are in
their ground rovibrational states, but is slower than vibrational relaxation in
homonuclear systems. Implications for sympathetic cooling of heteronuclear
molecules are discussed.Comment: 4 pages, 3 figure
Low temperature heat capacity of Fe_{1-x}Ga_{x} alloys with large magneostriction
The low temperature heat capacity C_{p} of Fe_{1-x}Ga_{x} alloys with large
magnetostriction has been investigated. The data were analyzed in the standard
way using electron () and phonon () contributions. The
Debye temperature decreases approximately linearly with increasing
Ga concentration, consistent with previous resonant ultrasound measurements and
measured phonon dispersion curves. Calculations of from lattice
dynamical models and from measured elastic constants C_{11}, C_{12} and C_{44}
are in agreement with the measured data. The linear coefficient of electronic
specific heat remains relatively constant as the Ga concentration
increases, despite the fact that the magnetoelastic coupling increases. Band
structure calculations show that this is due to the compensation of majority
and minority spin states at the Fermi level.Comment: 14 pages, 6 figure
Monitoring the Variable Interstellar Absorption toward HD 219188 with HST/STIS
We discuss the results of continued spectroscopic monitoring of the variable
intermediate-velocity (IV) absorption at v = -38 km/s toward HD 219188. After
reaching maxima in mid-2000, the column densities of both Na I and Ca II in
that IV component declined by factors >= 2 by the end of 2006. Comparisons
between HST/STIS echelle spectra obtained in 2001, 2003, and 2004 and HST/GHRS
echelle spectra obtained in 1994--1995 indicate the following: (1) The
absorption from the dominant species S II, O I, Si II, and Fe II is roughly
constant in all four sets of spectra -- suggesting that the total N(H) and the
(mild) depletions have not changed significantly over a period of nearly ten
years. (2) The column densities of the trace species C I (both ground and
excited fine-structure states) and of the excited state C II* all increased by
factors of 2--5 between 1995 and 2001 -- implying increases in the hydrogen
density n_H (from about 20 cm^{-3} to about 45 cm^{-3}) and in the electron
density n_e (by a factor >= 3) over that 6-year period. (3) The column
densities of C I and C II* -- and the corresponding inferred n_H and n_e --
then decreased slightly between 2001 and 2004. (4) The changes in C I and C II*
are very similar to those seen for Na I and Ca II. The relatively low total
N(H) and the modest n_H suggest that the -38 km/s cloud toward HD 219188 is not
a very dense knot or filament. Partial ionization of hydrogen appears to be
responsible for the enhanced abundances of Na I, C I, Ca II, and C II*. In this
case, the variations in those species appear to reflect differences in density
and ionization [and not N(H)] over scales of tens of AU.Comment: 33 pages, 6 figures, aastex, accepted to Ap
Exploration de l'écoulement dans un échangeur de chaleur tubulaire par vélocimétrie par images de particules
8 pagesL'étude du champ de vitesse à l'intérieur d'une maquette d'échangeur de chaleur en eau à l'échelle 1 est réalisée par vélocimétrie par images de particules. La géométrie tridimensionnelle de l'installation, ses faibles dimensions et la nature fortement instationnaire de l'écoulement imposent le choix de ce moyen de mesure. Un filtrage est appliqué aux images enregistrées, avant traitement par un algorithme de flot optique utilisant une programmation dynamique. Les déformations dues à la présence de dioptres optiques sont corrigées. Les mesures mettent en évidence de fortes variations de débit à travers les différents tubes de l'échangeur et un caractère non établi de l'écoulement. L'analyse des champs turbulents confirme ce comportement
The Conserved nhaAR Operon Is Drastically Divergent between B2 and Non-B2 Escherichia coli and Is Involved in Extra-Intestinal Virulence
The Escherichia coli species is divided in phylogenetic groups that differ in their virulence and commensal distribution. Strains belonging to the B2 group are involved in extra-intestinal pathologies but also appear to be more prevalent as commensals among human occidental populations. To investigate the genetic specificities of B2 sub-group, we used 128 sequenced genomes and identified genes of the core genome that showed marked difference between B2 and non-B2 genomes. We focused on the gene and its surrounding region with the strongest divergence between B2 and non-B2, the antiporter gene nhaA. This gene is part of the nhaAR operon, which is in the core genome but flanked by mobile regions, and is involved in growth at high pH and high sodium concentrations. Consistently, we found that a panel of non-B2 strains grew faster than B2 at high pH and high sodium concentrations. However, we could not identify differences in expression of the nhaAR operon using fluorescence reporter plasmids. Furthermore, the operon deletion had no differential impact between B2 and non-B2 strains, and did not result in a fitness modification in a murine model of gut colonization. Nevertheless, sequence analysis and experiments in a murine model of septicemia revealed that recombination in nhaA among B2 strains was observed in strains with low virulence. Finally, nhaA and nhaAR operon deletions drastically decreased virulence in one B2 strain. This effect of nhaAR deletion appeared to be stronger than deletion of all pathogenicity islands. Thus, a population genetic approach allowed us to identify an operon in the core genome without strong effect in commensalism but with an important role in extra-intestinal virulence, a landmark of the B2 strains
Heterodyne Spectroscopy of the 63 m O I Line in M42
We have used a laser heterodyne spectrometer to resolve the emission line
profile of the 63 micron 3P1 - 3P2 fine-structure transition of O I at two
locations in M42. Comparison of the peak antenna temperature with that of the
158 micron C II fine-structure line shows that the gas kinetic temperature in
the photodissociation region near theta1C is 175 - 220 K, the density is
greater than 2x10 ^5 cm-3, and the hydrogen column density is about 1.5x10 ^22
cm-2. A somewhat lower temperature and column density are found in the IRc2
region, most likely reflecting the smaller UV flux. The observed width of the O
I line is 6.8 km/s (FWHM) at theta1C, which is slightly broadened over the
intrinsic linewidth by optical depth effects. No significant other differences
between the O I and C II line profiles are seen, which shows that the narrow
emission from both neutral atomic oxygen and ionized carbon comes from the PDR.
The O I data do not rule out the possibility of weak broad-velocity emission
from shock-excited gas at IRc2, but the C II data show no such effect, as
expected from non-ionizing shock models.Comment: 11 pages including 2 postscript figures, uses aaspp4.st
Design and stability study of a paediatric oral solution of methotrexate 2mg/ml
Oral paediatric forms development by pharmaceutical industry is still insufficient. The present study was performed to propose an adapted and pleasant formulation of liquid oral formulation of MTX. The solution is composed of injectable methotrexate, water, Ora Sweet(®) and sodium bicarbonate. After 120 days storage, pH remained stable at about 8 in all formulations, insuring no risk of MTX precipitation. MTX content in solution formulation, determined by high performance liquid chromatography measurements, remained in the specifications of >90% of the initial concentration when stored at 4 and 25°C. Forced degradation of MTX by heat and acidic conditions allowed formation and detection of degradation products by the analytical method. Microbial study of the preparation shows that the solution remains in the specifications during all the storage, or after one sample each week during one month, eventually indicating the microbial properties are not affected by patient use. To conclude, we here propose a new MTX liquid formulation stable for at least 120 days
Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation
Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS). The platelet serotonin content was similar in S and NS but lower in FS. This was unexpected because the monoamine oxidase (MAO) activity, which catabolizes serotonin, was inhibited during smoking. However, the amount of platelet MAO was higher in S and FS than in NS. The persistent elevated MAO amount in FS prompted us to study the methylation of its gene promoter in an additional series of patients: it was markedly lower for S and FS vs. NS due to cigarette smoke-induced increase of nucleic acid demethylase activity. This smoking-induced demethylation of the MAO gene promoter, resulting in high MAO amount persisting long after quitting smoking, has cardiovascular consequences and could impact fields such as behavior, mental health, and cancer
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