Centro cívico cultural: integración de la arquitectura patrimonial y contemporánea a través de la cultura

Artículo de gradoEl centro histórico de Bogotá está compuesto por las localidades de Santa Fe, La Candelaria y Los Mártires; el Bronx, hace parte de la localidad de los Mártires. Este barrio ha tenido diferentes cambios por una serie de escenarios urbanísticos e históricos que lo han definido y determinado como es actualmente. Se plantea una renovación urbana y un centro cultural que potencialicen el sector, a partir de una interacción entre patrimonio, arquitectura contemporánea y sus ciudadanos.Introducción Antecedentes Metodología 1. Analítico 2. Proyectual 3. Propositivo Resultados Composición Sistema de Permanencias Estructura Discusión Conclusiones Referencias AnexosPregradoArquitect

From Global to Grassroots: The European Union, Transnational Advocacy, and Combating Violence Against Women

Resenha de:MONTOYA, Celeste, From global to grassroots: The European Union, transnational advocacy, and combating violence against women (2013, ainda não publicado no Brasil ou em português)

Prenatal stress and social support and postpartum anxiety. A descriptive study in a sample of mendocine women

Embarazo y puerperio son etapas que suponen un importante giro en la vida de una mujer, en ella suceden múltiples cambios que la vuelven más vulnerable a desarrollar desde variaciones en su estado emocional hasta sintomatología psicológica y psiquiátrica. Esto se suma a factores estresantes o ansiógenos provenientes del ambiente que pueden afectar el bienestar de la mujer en dichas etapas. Esto influye en el desarrollo del niño acarreando consecuencias negativas inmediatas y disminuyendo la calidad de su futura vida. Frente a ello, encontramos como factor protector el apoyo social que la madre percibe, el cual genera sentimientos de bienestar que disminuyen la angustia provocada por las situaciones estresantes

Anthropometric evaluation and micronutrients intake in patients submitted to laparoscopic Roux-en-Y gastric bypass with a postoperative period of ≥1 year

Backgroung - Bariatric surgery is indicated as the most effective treatment for morbid obesity; the Roux-en-Y gastric bypass (RYGB) is considered the procedure of choice. However, nutritional deficiency may occur in the postoperative period as a result of reduced gastric capacity and change in nutrients absorption in the gastrointestinal tract. The prescription of vitamin and mineral supplementation is a common practice after RYGB; however, it may not be sufficient to prevent micronutrient deficiencies. The aim of this study was to quantify the micronutrient intake in patients undergoing RYGB and verify if the intake of supplementation would be enough to prevent nutritional deficiencies. Methods - The study was conducted on 60 patients submitted to RYGB. Anthropometric, analytical, and nutritional intake data were assessed preoperatively and 1 and 2 years postoperatively. The dietary intake was assessed using 24-h food recall; the values of micronutrients evaluated (vitamin B12, folic acid, iron, and calcium) were compared to the dietary reference intakes (DRI). Results - There were significant differences (p < 0.05) between excess weight loss at the first and second year (69.9 ± 15.3 vs 9.6 ± 62.9 %). In the first and second year after surgery, 93.3 and 94.1 % of the patients, respectively, took the supplements as prescribed. Micronutrient deficiencies were detected in the three evaluation periods. At the first year, there was a significant reduction (p < 0.05) of B12, folic acid, and iron intake. Conclusions - Despite taking vitamin and mineral supplementation, micronutrient deficiencies are common after RYGB. In the second year after surgery, micronutrient intake remains below the DRI

Survival and Histopathological Study of Animals Bearing Ehrlich Tumor Treated With a Rhodium(II) Amidate

The survival of 90% of a tumor-bearing population treated with the complex Rh2 (CF3CONH)4 was examined and the pharmacological parameter Surv90 determined. Histopathological alterations raised for this drug in several tissues were studied in Balb-c mice. A Surv90 dose of 3.8x 10-5 mol/kg was found

Estudio de indicadores de suelo y planta para la programación del riego en cerezos jóvenes. Póster

En zonas áridas y semiáridas existe una necesidad constante de mejorar la eficiencia del uso del agua. En este sentido, el empleo de indicadores puede convertirse en una herramienta eficaz para confeccionar programas de riego más precisos. Durante el verano de 2018 y 2019, con el objetivo de estudiar la sensibilidad y la variabilidad de distintos indicadores de suelo y planta, se llevó a cabo un ensayo en cerezos jóvenes (Prunus avium L. ‘Lapins’). Tres tratamientos de riego aplicados fueron: con-trol ( CTL) regado para asegurar condiciones no limitantes de agua en el suelo, y dos tratamientos defi-citarios, MS y SS, los cuales fueron regados como CTL hasta finales de junio, momento a partir del cual se alternaron 2 ciclos consecutivos de supresión - reanudación del riego. Los árboles fueron recupera-dos cuando el potencial hídrico de tallo (Ψstem) alcanzó valores durante el primer y segundo ciclo de supresión de -1,3 y -1,7 MPa para MS y -1,6 y -2,3 MPa para SS. Los indicadores de suelo y planta estudiados fueron afectados por el déficit hídrico impuesto. La tasa de crecimiento diaria del tronco (TGR) y la máxima contracción diaria del tronco (MDS) mostraron una respuesta rápida al cambio de riego; sin embargo, ambos indicadores tuvieron una alta variabilidad. En este sentido, MDS mostró la mayor intensidad de señal, aunque la sensibilidad de este indicador fue mitigada por su coeficiente de variación (CV). Por otro lado, el contenido volumétrico de agua del suelo (θv) y la temperatura de la copa (Tc) exhibieron una alta sensibilidad debido a la baja variabilidad. Ψstem, indicador usado como referencia, mostró una estrecha relación con el resto de los indicadores estudiados, excepto con TGR. La relación observada entre MDS y Ψstem fue lineal hasta alcanzar valores de Ψstem de -1,3 MPa. Los resultados obtenidos sugieren que Ψstem es un indicador sensible al estrés con un bajo CV; Tc, la dife-rencia de temperatura de la copa y del aire y el índice de estrés del cultivo pueden ayudar a determinar, de forma rápida y sencilla, el estado hídrico del cultivo; y MDS podrías ser utilizado hasta valores de estrés moderados para la elaboración de programas de riego en cerezos jóvenes

Functional Convergence of Neurons Generated in the Developing and Adult Hippocampus

The dentate gyrus of the hippocampus contains neural progenitor cells (NPCs) that generate neurons throughout life. Developing neurons of the adult hippocampus have been described in depth. However, little is known about their functional properties as they become fully mature dentate granule cells (DGCs). To compare mature DGCs generated during development and adulthood, NPCs were labeled at both time points using retroviruses expressing different fluorescent proteins. Sequential electrophysiological recordings from neighboring neurons of different ages were carried out to quantitatively study their major synaptic inputs: excitatory projections from the entorhinal cortex and inhibitory afferents from local interneurons. Our results show that DGCs generated in the developing and adult hippocampus display a remarkably similar afferent connectivity with regard to both glutamate and GABA, the major neurotransmitters. We also demonstrate that adult-born neurons can fire action potentials in response to an excitatory drive, exhibiting a firing behavior comparable to that of neurons generated during development. We propose that neurons born in the developing and adult hippocampus constitute a functionally homogeneous neuronal population. These observations are critical to understanding the role of adult neurogenesis in hippocampal function

Reliable Activation of Immature Neurons in the Adult Hippocampus

Neurons born in the adult dentate gyrus develop, mature, and connect over a long interval that can last from six to eight weeks. It has been proposed that, during this period, developing neurons play a relevant role in hippocampal signal processing owing to their distinctive electrical properties. However, it has remained unknown whether immature neurons can be recruited into a network before synaptic and functional maturity have been achieved. To address this question, we used retroviral expression of green fluorescent protein to identify developing granule cells of the adult mouse hippocampus and investigate the balance of afferent excitation, intrinsic excitability, and firing behavior by patch clamp recordings in acute slices. We found that glutamatergic inputs onto young neurons are significantly weaker than those of mature cells, yet stimulation of cortical excitatory axons elicits a similar spiking probability in neurons at either developmental stage. Young neurons are highly efficient in transducing ionic currents into membrane depolarization due to their high input resistance, which decreases substantially in mature neurons as the inward rectifier potassium (Kir) conductance increases. Pharmacological blockade of Kir channels in mature neurons mimics the high excitability characteristic of young neurons. Conversely, Kir overexpression induces mature-like firing properties in young neurons. Therefore, the differences in excitatory drive of young and mature neurons are compensated by changes in membrane excitability that render an equalized firing activity. These observations demonstrate that the adult hippocampus continuously generates a population of highly excitable young neurons capable of information processing