The lesbian, gay, bisexual and transgender community online: discussions of bullying and self-disclosure in YouTube videos

Computer-mediated communication has become a popular platform for identity construction and experimentation as well as social interaction for those who identify as lesbian, gay, bisexual or transgender (LGBT). The creation of user-generated videos has allowed content creators to share experiences on LGBT topics. With bullying becoming more common amongst LGBT youth, it is important to obtain a greater understanding of this phenomenon. In our study, we report on the analysis of 151 YouTube videos which were identified as having LGBT- and bullying-related content. The analysis reveals how content creators openly disclose personal information about themselves and their experiences in a non-anonymous rhetoric with an unknown public. These disclosures could indicate a desire to seek friendship, support and provide empathy

Comparison of engagement and emotional responses of older and younger adults interacting with 3D cultural heritage artefacts on personal devices

The availability of advanced software and less expensive hardware allows museums to preserve and share artefacts digitally. As a result, museums are frequently making their collections accessible online as interactive, 3D models. This could lead to the unique situation of viewing the digital artefact before the physical artefact. Experiencing artefacts digitally outside of the museum on personal devices may affect the user's ability to emotionally connect to the artefacts. This study examines how two target populations of young adults (18–21 years) and the elderly (65 years and older) responded to seeing cultural heritage artefacts in three different modalities: augmented reality on a tablet, 3D models on a laptop, and then physical artefacts. Specifically, the time spent, enjoyment, and emotional responses were analysed. Results revealed that regardless of age, the digital modalities were enjoyable and encouraged emotional responses. Seeing the physical artefacts after the digital ones did not lessen their enjoyment or emotions felt. These findings aim to provide an insight into the effectiveness of 3D artefacts viewed on personal devices and artefacts shown outside of the museum for encouraging emotional responses from older and younger people

The Importance of Static Correlation in the Band Structure of High Temperature Superconductors

Recently we presented a new band structure for La(2-x)Sr(x)CuO(4) and other high temperature superconductors in which a second narrow band was seen to cross the primary band at the Fermi level. The existence of this second Fermi level band is in complete disagreement with the commonly accepted LDA band structure. Yet it provided a crucial piece of physics which led to an explanation for superconductivity and other unusual phenomena in these materials. In this work we present details as to the nature of the failure of conventional methods in deriving the band structure of the cuprates. In particular, we use a number of chemical analogues to describe the problem of static correlation in the band structure calculations and show how this can be corrected with the predictable outcome of a Fermi level band crossing.Comment: The Journal of Physical Chemistry, in press. References and figures updated. See www.firstprinciples.com for more information related to this wor

Recent advances in electronic structure theory and their influence on the accuracy of ab initio potential energy surfaces

Recent advances in electronic structure theory and the availability of high speed vector processors have substantially increased the accuracy of ab initio potential energy surfaces. The recently developed atomic natural orbital approach for basis set contraction has reduced both the basis set incompleteness and superposition errors in molecular calculations. Furthermore, full CI calculations can often be used to calibrate a CASSCF/MRCI approach that quantitatively accounts for the valence correlation energy. These computational advances also provide a vehicle for systematically improving the calculations and for estimating the residual error in the calculations. Calculations on selected diatomic and triatomic systems will be used to illustrate the accuracy that currently can be achieved for molecular systems. In particular, the F+H2 yields HF+H potential energy hypersurface is used to illustrate the impact of these computational advances on the calculation of potential energy surfaces

Producción de recursos educativos para la educación mediática en la escuela: Percepciones y necesidades de los profesores

A relevância da educação mediática tem sido crescentemente reconhecida no contexto internacional e também em Portugal. Às crianças e aos jovens é atribuída particular atenção, o que faz recair sobre a escola e os professores enorme responsabilidade, no sentido de contribuírem, desde cedo, para a formação de cidadãos informados, comunicadores eficazes e participantes ativos na cultura digital. A investigação realizada teve como principal objetivo conhecer as perceções dos professores do ensino básico e secundário sobre a educação mediática e sobre o seu papel e o da escola na promoção da literacia digital e mediática dos alunos, conhecer a sua formação e necessidades e, desta forma, reunir informação útil para orientar a elaboração de recursos educativos. Seguindo uma metodologia não experimental e descritiva, com base em dados obtidos a partir de um questionário online, elaborado pela equipa de investigadores, foi possível concluir que os professores atribuem grande relevância à educação mediática, reconhecem a importância da escola e de si próprios na formação dos alunos, mas revelam também uma formação deficitária neste domínio. Com base nestes resultados, foram elaborados dois recursos educativos, um livro e uma aplicação móvel, pensados para apoiar os professores na resposta ao desafio da implementação da educação mediática na escola.info:eu-repo/semantics/publishedVersio

Stakeholders' views and experiences of care and interventions for addressing frailty and pre-frailty: A meta-synthesis of qualitative evidence

Frailty is a common condition in older age and is a public health concern which requires integrated care and involves different stakeholders. This meta-synthesis focuses on experiences, understanding, and attitudes towards screening, care, intervention and prevention for frailty across frail and healthy older persons, caregivers, health and social care practitioners. Studies published since 2001 were identified through search of electronic databases; 81 eligible papers were identified and read in full, and 45 papers were finally included and synthesized. The synthesis was conducted with a meta-ethnographic approach. We identified four key themes: Uncertainty about malleability of frailty; Strategies to prevent or to respond to frailty; Capacity to care and person and family-centred service provision; Power and choice. A bottom-up approach which emphasises and works in synchrony with frail older people's and their families' values, goals, resources and optimisation strategies is necessary. A greater employment of psychological skills, enhancing communication abilities and tools to overcome disempowering attitudes should inform care organisation, resulting in more efficient and satisfactory use of services. Public health communication about prevention and management of frailty should be founded on a paradigm of resilience, balanced acceptance, and coping. Addressing stakeholders' views about the preventability of frailty was seen as a salient need

Enhancement of antibody-dependent cellular cytotoxicity is associated with treatment response to extracorporeal photopheresis in Sézary syndrome.

Sézary syndrome (SS) is a rare, leukemic type of cutaneous T-cell lymphoma (CTCL), for which extracorporeal photopheresis (ECP) is a first-line therapy. Reliable biomarkers to objectively monitor the response to ECP in patients with SS are missing. We examined the quantitative and qualitative impact of ECP on natural killer (NK) cell activity in SS patients, and especially their functional ability for antibody-dependent cell-mediated cytotoxicity (ADCC). Further, we addressed the question whether the magnitude of the effect on ADCC can be associated with the anti-cancer efficacy of ECP in SS patients. We assessed numbers of NK cells, ADCC activity, and treatment response based on blood tumor staging in a cohort of 13 SS patients (8 women, 5 men) treated with ECP as a first-line therapy. Blood samples were collected before treatment start and after an average of 9 months of uninterrupted ECP treatment. NK cell numbers were reduced in SS patients compared to healthy individuals and showed a tendency of recovery after long-term ECP treatment, independent of the clinical response to treatment. Patients with marginal increase (≤1.5 AU-fold) or lack of increase in ADCC activity failed to respond clinically to treatment, while patients with an increased ADCC activity showed a reduction in blood tumor burden. NK-mediated ADCC is selectively enhanced and might be a mechanism underlying the effect of ECP while in addition it can possibly serve as a reliable biomarker to objectively monitor response to ECP in patients with SS

O valor dos valores na utilização das tecnologias digitais em saúde

A implementação de Tecnologias Digitais em Saúde (TDS) regista uma expansão em vários países, estimulada pela perspetiva de ganhos de acessibilidade e equidade, mas também de eficiência na prestação dos cuidados de saúde. Contudo, o grau de adoção das TDS pelas pessoas varia consideravelmente, sendo necessário mapear os seus determinantes. No quadro dos fatores psicossociais, os valores têm um papel importante na explicação dos comportamentos dos indivíduos. Com recurso a um desenho correlacional, o presente estudo avalia o papel dos valores abertura à mudança (vs. Conservação) e autotranscendência (vs. Autopromoção) nos Comportamentos de Saúde Mediados por Tecnologias Digitais (CSMTD). Os valores foram conceptualizados a partir da Teoria dos Valores Humanos Básicos de Schwartz (1992), e considerou-se, ainda, o papel mediador da perceção de autoeficácia e moderador da idade. Participaram no estudo 396 indivíduos adultos (18-87 anos; M = 46; DP = 15) a residir em Portugal. Os resultados revelam que a autoeficácia é um preditor importante dos CSMTD e que os valores de abertura à mudança (vs. Conservação) e autotranscendência (vs. Autopromoção) têm um contributo relevante, que depende da idade dos participantes. Os resultados são discutidos no quadro do papel dos valores na mudança social e na comunicação associada à promoção das TDS.info:eu-repo/semantics/publishedVersio

Preliminary results of a systematic review focusing on the effectiveness of the interventions in preventing the progression of frailty in older adults

uropean Union’s Health Programme - Project FOCUSpublishe