Etude de faisabilité pour la création d'un club de tennis

Ce travail consiste à analyser la demande potentielle de ma région, qui concerne principalement 3 villages, pour la création de courts de tennis à proximité des habitants. Cette demande a été analysée par les données que j’ai récoltées sur le terrain en faisant du porte-à-porte dans les ménages de ces villages. L’étude de marché effectuée a été très positive et les habitants ont été très enthousiastes à l’idée d’avoir un club de tennis proche de chez eux. Plusieurs critères correspondants aux activités et aux services proposés par mon club ont été évalués par les sondés. Il en ressort que la convivialité, la proximité des terrains, la réservation en ligne, la rencontre d’autres joueurs et la facilité d’accès au club sont les aspects les plus importants selon eux. Grâce à cette analyse, j’ai pu les prendre en considération pour mon projet. Je me suis aperçu lors de mon étude que les habitants sont prêts à payer des cotisations annuelles parfois plus élevées que mes concurrents, ce qui est positif. Afin de connaître ces derniers, j’ai questionné une dizaine de clubs de tennis romands à travers un questionnaire qualitatif. Cette analyse m’a permis de mettre en avant quels sont leurs tarifs, leurs activités proposées, leurs avantages concurrentiels et leur méthode de financement. Grâce à ces deux enquêtes, j’ai pu créer un modèle d’affaires qui comporte 9 éléments essentiels à la faisabilité de mon projet. Ils représentent toutes les activités nécessaires à la mise en avant de ma proposition de valeur qui mènera à la fidélisation de la clientèle. Cette clientèle nécessite d’être écoutée et satisfaite, c’est pour cette raison que j’ai créé mon projet autour de celle-ci et de prendre en compte leurs avis et suggestions. Il m’a semblé important de créer quelque chose qui fasse plaisir à la communauté et pour le bien-être de la population. En effet, il existe dans ma région peu d’infrastructures sportives, les avis des sondés vont également dans ce sens. L’activité physique est très importante dans notre vie, car elle permet de nous garder en forme si elle est bien pratiquée. Selon les habitants, la création d’un club de tennis les motiverait à pratiquer plus souvent du sport, ceci étant mon objectif principal

Etude de faisabilité pour la création d'un club de tennis

Ce travail consiste à analyser la demande potentielle de ma région, qui concerne principalement 3 villages, pour la création de courts de tennis à proximité des habitants. Cette demande a été analysée par les données que j’ai récoltées sur le terrain en faisant du porte-à-porte dans les ménages de ces villages. L’étude de marché effectuée a été très positive et les habitants ont été très enthousiastes à l’idée d’avoir un club de tennis proche de chez eux. Plusieurs critères correspondants aux activités et aux services proposés par mon club ont été évalués par les sondés. Il en ressort que la convivialité, la proximité des terrains, la réservation en ligne, la rencontre d’autres joueurs et la facilité d’accès au club sont les aspects les plus importants selon eux. Grâce à cette analyse, j’ai pu les prendre en considération pour mon projet. Je me suis aperçu lors de mon étude que les habitants sont prêts à payer des cotisations annuelles parfois plus élevées que mes concurrents, ce qui est positif. Afin de connaître ces derniers, j’ai questionné une dizaine de clubs de tennis romands à travers un questionnaire qualitatif. Cette analyse m’a permis de mettre en avant quels sont leurs tarifs, leurs activités proposées, leurs avantages concurrentiels et leur méthode de financement. Grâce à ces deux enquêtes, j’ai pu créer un modèle d’affaires qui comporte 9 éléments essentiels à la faisabilité de mon projet. Ils représentent toutes les activités nécessaires à la mise en avant de ma proposition de valeur qui mènera à la fidélisation de la clientèle. Cette clientèle nécessite d’être écoutée et satisfaite, c’est pour cette raison que j’ai créé mon projet autour de celle-ci et de prendre en compte leurs avis et suggestions. Il m’a semblé important de créer quelque chose qui fasse plaisir à la communauté et pour le bien-être de la population. En effet, il existe dans ma région peu d’infrastructures sportives, les avis des sondés vont également dans ce sens. L’activité physique est très importante dans notre vie, car elle permet de nous garder en forme si elle est bien pratiquée. Selon les habitants, la création d’un club de tennis les motiverait à pratiquer plus souvent du sport, ceci étant mon objectif principal

Detection of a branched alkyl molecule in the interstellar medium: iso-propyl cyanide

The largest non-cyclic molecules detected in the interstellar medium (ISM) are organic with a straight-chain carbon backbone. We report an interstellar detection of a branched alkyl molecule, iso-propyl cyanide (i-C3H7CN), with an abundance 0.4 times that of its straight-chain structural isomer. This detection suggests that branched carbon-chain molecules may be generally abundant in the ISM. Our astrochemical model indicates that both isomers are produced within or upon dust grain ice mantles through the addition of molecular radicals, albeit via differing reaction pathways. The production of iso-propyl cyanide appears to require the addition of a functional group to a non-terminal carbon in the chain. Its detection therefore bodes well for the presence in the ISM of amino acids, for which such side-chain structure is a key characteristic.Comment: This is the author's version of the work. It is posted here by permission of the AAAS for non-commercial use. The definitive version was published in Science 345, 1584 (2014), doi:10.1126/science.125667

Complex organic molecules in the interstellar medium: IRAM 30 m line survey of Sagittarius B2(N) and (M)

The discovery of amino acids in meteorites and the detection of glycine in samples returned from a comet to Earth suggest that the interstellar chemistry is capable of producing such complex organic molecules. Our goal is to investigate the degree of chemical complexity that can be reached in the ISM. We performed an unbiased, spectral line survey toward Sgr B2(N) and (M) with the IRAM 30m telescope in the 3mm window. The spectra were analyzed with a simple radiative transfer model that assumes LTE but takes optical depth effects into account. About 3675 and 945 spectral lines with a peak signal-to-noise ratio higher than 4 are detected toward N and M, i.e. about 102 and 26 lines per GHz, respectively. This represents an increase by about a factor of 2 over previous surveys of Sgr B2. About 70% and 47% of the lines detected toward N and M are identified and assigned to 56 and 46 distinct molecules as well as to 66 and 54 less abundant isotopologues of these molecules, respectively. We also report the detection of transitions from 59 and 24 catalog entries corresponding to vibrationally or torsionally excited states of some of these molecules, respectively. Excitation temperatures and column densities were derived for each species but should be used with caution. Among the detected molecules, aminoacetonitrile, n-propyl cyanide, and ethyl formate were reported for the first time in space based on this survey, as were 5 rare isotopologues of vinyl cyanide, cyanoacetylene, and hydrogen cyanide. We also report the detection of transitions from within 12 new vib. or tors. excited states of known molecules. Although the large number of unidentified lines may still allow future identification of new molecules, we expect most of these lines to belong to vib. or tors. excited states or to rare isotopologues of known molecules for which spectroscopic predictions are currently missing. (abridged)Comment: Accepted for publication in A&A. 266 pages (39 pages of text), 111 tables, 8 figure

Platelet lysate as a serum substitute for 2D static and 3D perfusion culture of stromal vascular fraction cells from human adipose tissue

Fetal bovine serum (FBS) and fibroblast growth factor (FGF)-2 are key supplements for the culture of stromal vascular fraction (SVF) cells from adipose tissue, both for typical monolayer (2D) expansion and for streamlined generation of osteogenic-vasculogenic grafts in 3D perfusion culture. The present study investigates whether factors present in human platelet lysate (PL) could substitute for FBS and FGF-2 in 2D and 3D culture models of SVF cells from human lipoaspirates. SVF cells were grown in medium supplemented with 10% FBS+FGF-2 or with 5% PL. In 2D cultures, PL initially supported SVF cell proliferation, but resulted in growth arrest shortly after the first passage. Freshly isolated SVF cells cultured with both media under perfusion for 5 days within 3D ceramic scaffolds induced bone formation after subcutaneous implantation in nude mice. However, blood vessels of donor origin were generated only using FBS+FGF-2-cultured cells. This was unexpected, because the proportion of CD34+/CD31+ endothelial lineage cells was significantly higher with PL than that of FBS+FGF-2 (33% vs. 3%, respectively). These results support the use of PL as a substitute of FBS+FGF-2 for short-term culture of human SVF cells, and indicate that more specific serum-free formulations are required to maintain a functionally vasculogenic fraction of SVF cells expanded under 3D perfusion

Cache-Efficient Aggregation: Hashing Is Sorting

For decades researchers have studied the duality of hashing and sorting for the implementation of the relational operators, especially for efficient aggregation. Depending on the underlying hardware and software architecture, the specifically implemented algorithms, and the data sets used in the experiments, different authors came to different conclusions about which is the better approach. In this paper we argue that in terms of cache efficiency, the two paradigms are actually the same. We support our claim by showing that the complexity of hashing is the same as the complexity of sorting in the external memory model. Furthermore we make the similarity of the two approaches obvious by designing an algorithmic framework that allows to switch seamlessly between hashing and sorting during execution. The fact that we mix hashing and sorting routines in the same algorithmic framework allows us to leverage the advantages of both approaches and makes their similarity obvious. On a more practical note, we also show how to achieve very low constant factors by tuning both the hashing and the sorting routines to modern hardware. Since we observe a complementary dependency of the constant factors of the two routines to the locality of the input, we exploit our framework to switch to the faster routine where appropriate. The result is a novel relational aggregation algorithm that is cache-efficient---independently and without prior knowledge of input skew and output cardinality---, highly parallelizable on modern multi-core systems, and operating at a speed close to the memory bandwidth, thus outperforming the state-of-the-art by up to 3.7x

Charge-state distribution of Li ions from the β\beta decay of laser-trapped 6^{6}He atoms

Background: The accurate determination of atomic final states following nuclear $\beta$ decay plays an important role in many experiments. In particular, the charge state distributions of ions following nuclear $\beta$ decay are important for determinations of the $\beta-\nu$ angular correlation with improved precision. Purpose: Our measurement aims at providing benchmarks to test theoretical calculations. Method: The kinematics of Li$^{n+}$ ions produced following the $\beta$ decay of $^6{\rm He}$ within an electric field were measured using $^6{\rm He}$ atoms in the metastable $(1s2s,~{^3S_1})$ and in the $(1s2p,~{^3P_2})$ states confined by a magneto-optical trap. The electron shake-off probabilities were deduced including their dependence on ion energy. Results: We find significant discrepancies on the fractions of Li ions in the different charge states with respect to a recent calculation and discuss a plausible explanation. We also point out that there is no explanation for a large discrepancy between the same calculation and a previous measurement of the Li-ion energy dependence of the charge distribution from decays of the electronic ground state

Resolving desorption of complex organic molecules in a hot core: Transition from non-thermal to thermal desorption or two-step thermal desorption?

Using the high angular resolution provided by the ALMA interferometre we want to resolve the COM emission in the hot molecular core Sagittarius B2(N1) and thereby shed light on the desorption process of Complex Organic Molecules (COMs) in hot cores. We use data taken as part of the 3 mm spectral line survey Re-exploring Molecular Complexity with ALMA (ReMoCA) to investigate the morphology of COM emission in Sagittarius B2(N1). Spectra of ten COMs are modelled under the assumption of LTE and population diagrams are derived for positions at various distances to the south and west from the continuum peak. Based on this analysis, resolved COM rotation temperature and COM abundance profiles are derived. Based on the morphology, a rough separation into O- and N-bearing COMs can be done. Temperature profiles are in agreement with expectations of protostellar heating of an envelope with optically thick dust. Abundance profiles reflect a similar trend as seen in the morphology and, to a great extent, agree with results of astrochemical models that, besides the co-desorption with water, predict that O-bearing COMs are mainly formed on dust grain surfaces at low temperatures while at least some N-bearing COMs and CH$_3$CHO are substantially formed in the gas phase at higher temperatures. Our observational results, in comparison with model predictions, suggest that COMs that are exclusively or to a great extent formed on dust grains desorb thermally at ~100 K from the grain surface likely alongside water. Non-zero abundance values below ~100 K suggest that another desorption process is at work at these low temperatures: either non-thermal desorption or partial thermal desorption related to lower binding energies experienced by COMs in the outer, water-poor ice layers. In either case, this is the first time that the transition between two regimes of COM desorption has been resolved in a hot core.Comment: Accepted for publication in A&

Dimethyl ether in its ground state, v=0, and lowest two torsionally excited states, v11=1 and v15=1, in the high-mass star-forming region G327.3-0.6

The goal of this paper is to determine the respective importance of solid state vs. gas phase reactions for the formation of dimethyl ether. This is done by a detailed analysis of the excitation properties of the ground state and the torsionally excited states, v11=1 and v15=1, toward the high-mass star-forming region G327.3-0.6. With the Atacama Pathfinder EXperiment 12 m submillimeter telescope, we performed a spectral line survey. The observed spectrum is modeled assuming local thermal equilibrium. CH3OCH3 has been detected in the ground state, and in the torsionally excited states v11=1 and v15=1, for which lines have been detected here for the first time. The emission is modeled with an isothermal source structure as well as with a non-uniform spherical structure. For non-uniform source models one abundance jump for dimethyl ether is sufficient to fit the emission, but two components are needed for the isothermal models. This suggests that dimethyl ether is present in an extended region of the envelope and traces a non-uniform density and temperature structure. Both types of models furthermore suggest that most dimethyl ether is present in gas that is warmer than 100 K, but a smaller fraction of 5%-28% is present at temperatures between 70 and 100 K. The dimethyl ether present in this cooler gas is likely formed in the solid state, while gas phase formation probably is dominant above 100 K. Finally, the v11=1 and v15=1 torsionally excited states are easily excited under the density and temperature conditions in G327.3-0.6 and will thus very likely be detectable in other hot cores as well.Comment: 12 pages (excluding appendices), 8 figures, A&A in pres

Rotational and high-resolution infrared spectrum of HC3_3N: global ro-vibrational analysis and improved line catalogue for astrophysical observations

HC$_3$N is an ubiquitous molecule in interstellar environments, from external galaxies, to Galactic interstellar clouds, star forming regions, and planetary atmospheres. Observations of its rotational and vibrational transitions provide important information on the physical and chemical structure of the above environments. We present the most complete global analysis of the spectroscopic data of HC$_3$N. We have recorded the high-resolution infrared spectrum from 450 to 1350 cm$^{-1}$, a region dominated by the intense $\nu_5$ and $\nu_6$ fundamental bands, located at 660 and 500 cm$^{-1}$, respectively, and their associated hot bands. Pure rotational transitions in the ground and vibrationally excited states have been recorded in the millimetre and sub-millimetre regions in order to extend the frequency range so far considered in previous investigations. All the transitions from the literature and from this work involving energy levels lower than 1000 cm$^{-1}$ have been fitted together to an effective Hamiltonian. Because of the presence of various anharmonic resonances, the Hamiltonian includes a number of interaction constants, in addition to the conventional rotational and vibrational l-type resonance terms. The data set contains about 3400 ro-vibrational lines of 13 bands and some 1500 pure rotational lines belonging to 12 vibrational states. More than 120 spectroscopic constants have been determined directly from the fit, without any assumption deduced from theoretical calculations or comparisons with similar molecules. An extensive list of highly accurate rest frequencies has been produced to assist astronomical searches and data interpretation. These improved data, have enabled a refined analysis of the ALMA observations towards Sgr B2(N2).Comment: 35 pages, 14 figures, accepted for pubblication in ApJ Supplemen