L’attuale situazione sociolinguistica nel Veneto

Die vorliegende Diplomarbeit setzt sich mit der aktuellen soziolinguistischen Situation im Veneto (zu Deutsch: Venetien) auseinander. Ziel meiner Ausführungen ist es, einen Einblick in die aktuelle, dialektale Sprachsituation in der nordöstlichen Region Italiens zu gewähren. Ein wesentlicher Aspekt der Diplomarbeit widmet sich den unmittelbaren Zusammenhängen zwischen dem dialektalen Sprachgebrauch und der Gesellschaft. Leitende Fragen hierzu lauteten: Was sind die Gründe für die Präsenz und die Lebendigkeit dieses Dialekts? In welchen Bereichen wird er angewendet, und von wem? Welche Rolle spielt der Dialekt in der venetischen Gesellschaft? Welche Rolle spielt die Region selbst in Bezug auf die Erhaltung und die Wahrung des eigenen Sprachguts? Der Beginn der Arbeit wird von einer allgemeinen Übersicht der dialektalen Sprachsituation Italiens gestaltet, um sodann näher auf die linguistischen Merkmale des „dialetto veneto“ einzugehen. In weiterer Folge wird untersucht, welche Initiativen und Maßnahmen die Region unternimmt, um das eigene dialektale Sprachgut zu wahren und zu fördern. Im Mittelpunkt des nächsten Kapitels steht das kulturelle Panorama Venetiens. Hier wird im Besonderen auf die Beziehung zwischen dialektaler Sprache und Poesie eingegangen. Die Präsentation der dialektalen Zeitschrift „Quatro Ciàcoe“, sowie ein anschließendes Interview mit ihrem Präsidenten, Vittorio Ingegneri, bilden den Schlusspunkt der Arbeit. In ausführlicher Weise beantwortete der Experte meine Fragen zu folgenden Aspekten: Der Wert des Dialekts innerhalb der Gesellschaft, Dialekt und Schule, Dialekt und Kultur, Fragen zur Zeitschrift, Dialekt und Politik

Die Instabilität queerer Raumpraxis

In einer Spurensuche nach verlorenen und verdrängten Orten queerer Stadtkultur kommen Protagonist*innen zu Wort, die das Leben, die politische Situation von LGBTQIA+-Communities und (Stadt-)Räume gestaltet und die queere Geschichtsschreibung Berlins geprägt haben. Sie sprechen exemplarisch über die Diskothek Lipstick, die Deutsche Oper als schwuler Treffpunkt, den Frauenbuchladen Lilith, das feministische Archiv FFBIZ und die Klappe im Preußenpark. Diese Oral Histories stellen die Orte den Stimmen der Protagonist*innen in collagenhaften Audio-Features gegenüber. Sie erzählen von vergessenen Möglichkeitsräumen und Sehnsuchtsorten, von Räumen queerer Identifikation und Fürsorge, von Protest, Widerstand und Gleichberechtigung. Dabei wird eines klar: Neben Idealismus und dem Drang nach Selbstermächtigung sind queere Raumpraktiken geprägt von Unsicherheiten und Instabilität. Die Hörbilder werden von Vignetten begleitet, die Schlaglichter auf mögliche Ursachen von Prozessen der Instabilität werfen und die Erfahrungen von Protagonist*innen der 1970er- bis 1990er-Jahre mit aktuellen urbanen Transformationsprozessen in Zusammenhang stellen

Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients

PURPOSE : FAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The purpose of this study is the head-to-head intra-individual comparison of 68Ga- FAPI versus standard-of-care 18F-FDG in PET/CT in organ biodistribution and tumor uptake in patients with various cancers. MARERILA AND METHODS : This international retrospective multicenter analysis included PET/CT data from 71 patients from 6 centers who underwent both 68Ga-FAPI and 18F-FDG PET/CT within a median time interval of 10 days (range 1–89 days). Volumes of interest (VOIs) were manually drawn in normal organs and tumor lesions to quantify tracer uptake by SUVmax and SUVmean. Furthermore, tumor-to-background ratios (TBR) were generated (SUVmax tumor/ SUVmax organ). RESULTS : A total of 71 patients were studied of, which 28 were female and 43 male (median age 60). In 41 of 71 patients, the primary tumor was present. Forty-three of 71 patients exhibited 162 metastatic lesions. 68Ga-FAPI uptake in primary tumors and metastases was comparable to 18F-FDG in most cases. The SUVmax was significantly lower for 68Ga-FAPI than 18F-FDG in background tissues such as the brain, oral mucosa, myocardium, blood pool, liver, pancreas, and colon. Thus, 68Ga-FAPI TBRs were significantly higher than 18F-FDG TBRs in some sites, including liver and bone metastases. CONCLUSION : Quantitative tumor uptake is comparable between 68Ga-FAPI and 18F-FDG, but lower background uptake in most normal organs results in equal or higher TBRs for 68Ga-FAPI. Thus, 68Ga-FAPI PET/CT may yield improved diagnostic information in various cancers and especially in tumor locations with high physiological 18F-FDG uptake.Open Access funding by Projekt DEAL.http://link.springer.com/journal/259am2022Nuclear Medicin

Preliminary Results for the Multi-Robot, Multi-Partner, Multi-Mission, Planetary Exploration Analogue Campaign on Mount Etna

This paper was initially intended to report on the outcome of the twice postponed demonstration mission of the ARCHES project. Due to the global COVID pandemic, it has been postponed from 2020, then 2021, to 2022. Nevertheless, the development of our concepts and integration has progressed rapidly, and some of the preliminary results are worthwhile to share with the community to drive the dialog on robotics planetary exploration strategies. This paper includes an overview of the planned 4-week campaign, as well as the vision and relevance of the missiontowards the planned official space missions. Furthermore, the cooperative aspect of the robotic teams, the scientific motivation, the sub task achievements are summarised

Finally! Insights into the ARCHES Lunar Planetary Exploration Analogue Campaign on Etna in summer 2022

This paper summarises the first outcomes of the space demonstration mission of the ARCHES project which could have been performed this year from 13 june until 10 july on Italy’s Mt. Etna in Sicily. After the second postponement related to COVID from the initially for 2020 planed campaign, we are now very happy to report, that the whole campaign with more than 65 participants for four weeks has been successfully conduced. In this short overview paper, we will refer to all other publication here on IAC22. This paper includes an overview of the performed 4-week campaign and the achieved mission goals and first results but also share our findings on the organisational and planning aspects

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

Additional file 1 of Effects of extracorporeal CO2 removal on gas exchange and ventilator settings: a systematic review and meta-analysis

Additional file 1. Additional File A. PRISMA 2020 checklist. Additional File B. Criteria for considering studies for this review. Additional File C. Search strategy. Additional Table S1. Studies. Additional Table S2. Devices designed for ECCO2R and their basic specifications. Additional Table S3. Available data from included studies. Additional Table S4. Adverse Events from observational studies. Additional Figure S1: Risk of bias assessment (Robins-I tool). Additional Figure S2 a, and b: Change of (a) PaCO2, mmHg and (b) pH within 24 hours after initiating ECCO2R (all studies). Additional Figure S3 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2O within 24 hours after initiating ECCO2R (all studies). Additional Figure S4 a, b, and c: Change of (a) plateau pressure, cmH2O, (b) tidal volume, mL, and (c) respiratory rate, breaths/min within 24 hours after initiating ECCO2R (all studies). Additional Figure S5 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2Owithin 24 hours after initiating ECCO2R (diagnoses subgroups). Additional Figure S6 a, and b: Change of (a) PaCO2, mmHg (a) and (b) PaO2/FiO2 ratio, mmHg within 24 hours after initiating ECCO2R according to diagnosis and extraction. Additional Figure S7 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2O within 24 hours after initiating ECCO2R (lower extraction and higher extraction subgroups). Additional Figure S8 a, and b: Change of (a) PaO2/FiO2 ratio, mmHg and (b) PEEP, cmH2O within 24 hours after initiating ECCO2R according to diagnosis and extraction. Additional Figure S9 a, and b: Change of (a) plateau pressure, cmH2O and (b) tidal volume, mL within 24 hours after initiating ECCO2R (lower extraction and higher extraction subgroups). Additional Figure S10 a, b, and c: Change of (a) plateau pressure, cmH2O, (b) tidal volume, mL, and (c) respiratory rate, breaths/min within 24 hours after initiating ECCO2R according to diagnosis and extraction. Additional Figure S11 a-g: (a) PaCO2, mmHg, (b) pH, (c) PaO2/FiO2 ratio, mmHg and (d) PEEP, cmH2O, (e) plateau pressure, cmH2O, (f) tidal volume, mL and (g) respiratory rate, breaths/min according to risk of bias

German Aerospace Center’s advanced robotic technologyfor future lunar scientific missions

he Earth's moon is currently an object of interest of many space agencies for unmanned robotic missions within this decade. Besides future prospects for building lunar gateways as support to human space flight, the Moon is an attractive location for scientific purposes. Not only will its study give insight on the foundations of the Solar System but also its location, uncontaminated by the Earth's ionosphere, represents a vantage point for the observation of the Sun and planetary bodies outside the Solar System. Lunar exploration has been traditionally conducted by means of single-agent robotic assets, which is a limiting factor for the return of scientific missions. The German Aerospace Center (DLR) is developing fundamental technologies towards increased autonomy of robotic explorers to fulfil more complex mission tasks through cooperation. This paper presents an overview of past, present and future activities of DLR towards highly autonomous systems for scientific missions targeting the Moon and other planetary bodies. The heritage from the Mobile Asteroid Scout (MASCOT), developed jointly by DLR and CNES and deployed on asteroid Ryugu on 3 October 2018 from JAXA's Hayabusa2 spacecraft, inspired the development of novel core technologies towards higher efficiency in planetary exploration. Together with the lessons learnt from the ROBEX project (2012–2017), where a mobile robot autonomously deployed seismic sensors at a Moon analogue site, this experience is shaping the future steps towards more complex space missions. They include the development of a mobile rover for JAXA's Martian Moons eXploration (MMX) in 2024 as well as demonstrations of novel multi-robot technologies at a Moon analogue site on the volcano Mt Etna in the ARCHES project. Within ARCHES, a demonstration mission is planned from the 14 June to 10 July 2021,1 during which heterogeneous teams of robots will autonomously conduct geological and mineralogical analysis experiments and deploy an array of low-frequency antennas to measure Jovian and solar bursts. This article is part of a discussion meeting issue ‘Astronomy from the Moon: the next decades'

The ARCHES Space-Analogue Demonstration Mission: Towards Heterogeneous Teams of Autonomous Robots for Collaborative Scientific Sampling in Planetary Exploration

Teams of mobile robots will play a crucial role in future missions to explore the surfaces of extraterrestrial bodies. Setting up infrastructure and taking scientific samples are expensive tasks when operating in distant, challenging, and unknown environments. In contrast to current single-robot space missions, future heterogeneous robotic teams will increase efficiency via enhanced autonomy and parallelization, improve robustness via functional redundancy, as well as benefit from complementary capabilities of the individual robots. In this letter, we present our heterogeneous robotic team, consisting of flying and driving robots that we plan to deploy on scientific sampling demonstration missions at a Moon-analogue site on Mt. Etna, Sicily, Italy in 2021 as part of the ARCHES project. We describe the robots' individual capabilities and their roles in two mission scenarios. We then present components and experiments on important tasks therein: automated task planning, high-level mission control, spectral rock analysis, radio-based localization, collaborative multi-robot 6D SLAM in Moon-analogue and Mars-like scenarios, and demonstrations of autonomous sample return

Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients

PurposeFAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The purpose of this study is the head-to-head intra-individual comparison of 68Ga-FAPI versus standard-of-care 18F-FDG in PET/CT in organ biodistribution and tumor uptake in patients with various cancers.Material and methodsThis international retrospective multicenter analysis included PET/CT data from 71 patients from 6 centers who underwent both 68Ga-FAPI and 18F-FDG PET/CT within a median time interval of 10 days (range 1-89 days). Volumes of interest (VOIs) were manually drawn in normal organs and tumor lesions to quantify tracer uptake by SUVmax and SUVmean. Furthermore, tumor-to-background ratios (TBR) were generated (SUVmax tumor/ SUVmax organ).ResultsA total of 71 patients were studied of, which 28 were female and 43 male (median age 60). In 41 of 71 patients, the primary tumor was present. Forty-three of 71 patients exhibited 162 metastatic lesions. 68Ga-FAPI uptake in primary tumors and metastases was comparable to 18F-FDG in most cases. The SUVmax was significantly lower for 68Ga-FAPI than 18F-FDG in background tissues such as the brain, oral mucosa, myocardium, blood pool, liver, pancreas, and colon. Thus, 68Ga-FAPI TBRs were significantly higher than 18F-FDG TBRs in some sites, including liver and bone metastases.ConclusionQuantitative tumor uptake is comparable between 68Ga-FAPI and 18F-FDG, but lower background uptake in most normal organs results in equal or higher TBRs for 68Ga-FAPI. Thus, 68Ga-FAPI PET/CT may yield improved diagnostic information in various cancers and especially in tumor locations with high physiological 18F-FDG uptake