Aplicación de la gestión logística para reducir costos de inventarios en la empresa Astilleros Luguensi SAC, Chimbote – 2021

La presente investigación tuvo como objetivo aplicar la gestión logística para reducir los costos de inventario de la empresa Astilleros Luguensi SAC. La metodología aplicada fue de tipo aplicada, enfoque cuantitativo y diseño pre-experimental. Así mismo se plantearon cuatro objetivos específicos como Diagnosticar la situación de la gestión logística, utilizando los instrumentos Check list, diagrama de Ishikawa y Pareto, donde se determinó que el 26.67% se cumple y mientras que el 73.33% no cumplen con una gestión logística, para determinar los costos de inventarios iniciales, se usó como instrumento formato de clasificación ABC, formato de costo de inventarios, donde determinó que el costo de inventarios del 2021 de S/756,002.12 soles, así mismo para implementar la gestión logística, se propuso un procedimiento para el área de logística, un modelo de calificación de proveedores, un modelo de distribución y se determinó un modelo de inventarios para los materiales identificados como tipo A, donde se identificó la demanda proyectada, cantidad económica de pedido, inventarios de seguridad que permita reducir los costos de inventarios y finalmente como conclusión se obtuvo un impacto positivo obteniendo una reducción de los costos de inventarios a un ahorro total del 58% , que corresponde a S/ 435,835.67 soles

Microvessel rupture induced by high-intensity therapeutic ultrasound—a study of parameter sensitivity in a simple in vivo model

Safety analyses of transcranial therapeutic ultrasound procedures require knowledge of the dependence of the rupture probability and rupture time upon sonication parameters. As previous vessel-rupture studies have concentrated on a specific set of exposure conditions, there is a need for more comprehensive parametric studies. Probability of rupture and rupture times were measured by exposing the large blood vessel of a live earthworm to high-intensity focused ultrasound pulse trains of various characteristics. Pressures generated by the ultrasound transducers were estimated through numerical solutions to the KZK (Khokhlov-Zabolotskaya-Kuznetsov) equation. Three ultrasound frequencies (1.1, 2.5, and 3.3 MHz) were considered, as were three pulse repetition frequencies (1, 3, and 10 Hz), and two duty factors (0.0001, 0.001). The pressures produced ranged from 4 to 18 MPa. Exposures of up to 10 min in duration were employed. Trials were repeated an average of 11 times. No trends as a function of pulse repetition rate were identifiable, for either probability of rupture or rupture time. Rupture time was found to be a strong function of duty factor at the lower pressures; at 1.1 MHz the rupture time was an order of magnitude lower for the 0.001 duty factor than the 0.0001. At moderate pressures, the difference between the duty factors was less, and there was essentially no difference between duty factors at the highest pressure. Probability of rupture was not found to be a strong function of duty factor. Rupture thresholds were about 4 MPa for the 1.1 MHz frequency, 7 MPa at 3.3 MHz, and 11 MPa for the 2.5 MHz, though the pressure value at 2.5 MHz frequency will likely be reduced when steep-angle corrections are accounted for in the KZK model used to estimate pressures. Mechanical index provided a better collapse of the data (less separation of the curves pertaining to the different frequencies) than peak negative pressure, for both probability of rupture and rupture time. The results provide a database with which investigations in more complex animal models can be compared, potentially establishing trends by which bioeffects in human vessels can be estimated.https://doi.org/10.1186/s40349-017-0082-

Engaged parenting, gender, and children's time use in transnational families : an assessment spanning three global regions

Funding support for this study is from Singapore Ministry of Education Academic Research Fund Tier 2 (MOE2015‐T2‐1‐008); Hong Kong Research Grants Council through its General Research Fund (Project 17606815); Wellcome Trust UK (GR079946/B/06/Z and GR079946/Z/06/Z).Global circuits of migration regularly separate parents from children. How families navigate this separation has changed markedly. The sharp decline in the cost of international communication makes possible new forms of transnational parenting. In many contexts, migrants are now actively engaged parents, involved in decisions, knowledgeable of children's schooling, employment, and activities, and in some cases, even conversant face‐to‐face with children via videoconferencing. These practices, however, are not universal. We use data from surveys in 3 countries to document the frequency and variability of intensive, engaged transnational parenting in the diverse global regions of Asia, Africa, and the Americas. We then ask whether the organisation of children's lives—specifically, time allocated to school homework, leisure, and household chores—varies by the degree to which migrant parents stay connected to sending homes. The gender of the migrant parent, stay‐behind caregiver, and the gender of the child emerge as explanatory factors for engaged parenting and children's time use. However, and unexpectedly, in the Philippines, migrant mothers are less likely to practice engaged parenting. In sending households, girls in two of the three countries spend more time doing household chores than boys, but parental migration does not mitigate this difference. Although we find some evidence of more traditional gender practices, we also find exceptions that suggest potentially fruitful avenues for future research.Publisher PDFPeer reviewe

Análisis de la red hídrica de la subcuenca Yanayacu, Ancash-Perú, 2022

The research work was carried out in the sub-basin of the Yanayacu River (Ancash - Peru), its objectives were: to characterize the sub-basin of the Yanayacu River and the contrast of the existing empirical equations in the scientific literature related to the water network. The 20i Recuay digital charts and the Arcgis 10.8 software were used as materials. Horton's laws of channel number, mean channel length for a given order, and Melton's law were confirmed for the Yanayacu River sub-basin. Also, an exponential equation was obtained for the prediction of the total number of channels as a function of the channel order and a potential equation for the prediction of the total length of channels as a function of the total number of channels of a given order. Keywords: water network; Horton; Melton; number of channels; channel orderEl trabajo de investigación se realizó en la subcuenca del río Yanayacu (Ancash – Perú), se tuvo como objetivos: realizar la caracterización de la subcuenca del río Yanayacu y la contrastación de las ecuaciones empíricas existentes en la literatura científica relacionadas a la red hídrica. Se emplearon como materiales las cartas digitales 20i Recuay y el software Arcgis 10.8. Las leyes de Horton del número de cauces, de la longitud media de los cauces para un orden dado y la ley de Melton se confirmaron para la subcuenca del río Yanayacu. También, se obtuvo una ecuación  exponencial para la predicción del número de cauces total en función del orden del cauce  y una ecuación potencial para la predicción de la longitud total de cauces en función del número de cauces total de un orden determinado. Palabras clave: red hídrica; Horton; Melton; número de cauces; orden de cauce

Osteoporosis and Prevalent Fractures among Adult Filipino Men Screened for Bone Mineral Density in a Tertiary Hospital

BackgroundOsteoporosis in men is markedly underdiagnosed and undertreated despite higher morbidity and mortality associated with fractures. This study aimed to characterize adult Filipino men with osteopenia, osteoporosis and prevalent fractures.MethodsA cross-sectional study of 184 Filipino men ≥50 years screened for bone mineral density was performed. Age, weight, body mass index (BMI), Osteoporosis Self-Assessment Tool for Asians (OSTA) score, smoking status, family history of fracture, diabetes mellitus, physical inactivity, and T-score were considered.ResultsOf the 184 patients, 40.2% and 29.9% have osteopenia and osteoporosis. Sixteen (21.6%) and 18 (32.1%) osteopenic and osteoporotic men have fragility hip, spine, or forearm fractures. Men aged 50 to 69 years have the same risk of osteoporosis and fractures as those ≥70 years. While hip fractures are higher in osteoporotic men, vertebral fractures are increased in both osteopenic and osteoporotic men. Mere osteopenia predicts the presence of prevalent fractures. A high risk OSTA score can predict fracture. A BMI <21 kg/m2 (P<0.05) and current smoking are associated with osteoporosis.ConclusionA significant fraction of Filipino men with osteopenia and osteoporosis have prevalent fractures. Our data suggest that fractures occur in men <70 years even before osteoporosis sets in. Low BMI, high OSTA score, and smoking are significant risk factors of osteoporosis

Examining the relationship between fetal cortical thickness, gestational age, and maternal psychological distress

In utero exposure to maternal stress, anxiety, and depression has been associated with reduced cortical thickness (CT), and CT changes, in turn, to adverse neuropsychiatric outcomes. Here, we investigated global and regional (G/RCT) changes associated with fetal exposure to maternal psychological distress in 265 brain MRI studies from 177 healthy fetuses of low-risk pregnant women. GCT was measured from cortical gray matter (CGM) voxels; RCT was estimated from 82 cortical regions. GCT and RCT in 87% of regions strongly correlated with GA. Fetal exposure was most strongly associated with RCT in the parahippocampal region, ventromedial prefrontal cortex, and supramarginal gyrus suggesting that cortical alterations commonly associated with prenatal exposure could emerge in-utero. However, we note that while regional fetal brain involvement conformed to patterns observed in newborns and children exposed to prenatal maternal psychological distress, the reported associations did not survive multiple comparisons correction. This could be because the effects are more subtle in this early developmental window or because majority of the pregnant women in our study did not experience high levels of maternal distress. It is our hope that the current findings will spur future hypothesis-driven studies that include a full spectrum of maternal mental health scores

Living arrangements in four Asian countries: a comparative perspective

10.1007/BF00972034Journal of Cross-Cultural Gerontology101-2145-16

Metabolic analyses of interspecific tomato recombinant inbred lines for fruit quality improvement

Elucidating the determinants of tomato nutritional value and fruit quality to introduce improved varieties on the international market represents a major challenge for crop biotechnology. Different strategies can be undertaken to exploit the natural variability of Solanum to re-incorporate lost allelic diversity into commercial varieties. One of them is the characterization of selected germplasm for breeding programs. To achieve this goal, 18 RILs (S. lycopersicum × S. pimpinellifolium) were comprehensively phenotyped for fruit polar metabolites and quality associated traits. Metabolites were quantified by GC–MS and 1H NMR. Integrative analyses by neuronal clustering and network construction revealed that fruit properties are strongly associated with the metabolites aspartate, serine, glutamate and 2-oxoglutarate. Shelf life and firmness appeared to be linked to malate content. By a comparative analysis of the whole data set, ten RILs presented higher number of traits with positive effect than the S. lycopersicum × S. pimpinellifolium hybrid. Thus, these lines can be proposed as promising candidates for breeding programs aimed to improve fruit quality.Fil: Lopez, Mariana Gabriela. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Zanor, María Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Pratta, Guillermo Raúl. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Cs.agrarias. Departamento de Biologia. Cat.de Genetica; ArgentinaFil: Stegmayer, Georgina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Tecnológica Nacional; ArgentinaFil: Boggio, Silvana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Conte, Mariana. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bermudez Salazar, Luisa Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; ArgentinaFil: Coluccio Leskow, Carla. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rodríguez, Gustavo Rubén. Universidad Nacional de Rosario. Facultad de Cs.agrarias. Departamento de Biologia. Cat.de Genetica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Picardi, Liliana Amelia. Universidad Nacional de Rosario. Facultad de Cs.agrarias. Departamento de Biologia. Cat.de Genetica; ArgentinaFil: Zorzoli, Roxana. Universidad Nacional de Rosario. Facultad de Cs.agrarias. Departamento de Biologia. Cat.de Genetica; ArgentinaFil: Fernie, Alisdair R.. Max Planck Institute For Molecular Plant Physiology; AlemaniaFil: Milone, Diego Humberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Litoral. Facultad de Ingeniería y Ciencias Hídricas. Departamento de Informática. Laboratorio de Investigaciones en Señales e Inteligencia Computacional; ArgentinaFil: Asis, Ramón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; ArgentinaFil: Valle, Estela Marta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Carrari, Fernando Oscar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Biotecnología; Argentin