35 research outputs found

    Debate on Graduate Women\u27s Studies at George Washington University

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    The M.A. program in women\u27s studies at George Washington University is undergoing dramatic changes in focus and structure. As students and graduates, we believe these changes raise questions about the quality of our Women\u27s Studies Program, especially its lack of feminist focus and content. A radical feminist believes that women are a distinct group, restricted by custom and law from complete participation in society. Moreover, feminists believe that women\u27s lives—and the female experience—have worth and should be preserved. Therefore, feminists strive for equity, recognition of the importance of the female world, and fundamental change in the social order

    Salvage chemotherapy and autologous stem cell transplantation for peripheral T-cell lymphoma: a subset analysis of the Canadian Cancer Trials Group LY.12 randomized phase 3 study*

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    Peripheral T-cell lymphoma (PTCL) is a rare, heterogeneous malignancy. Of the 619 patients with relapsed and refractory (R/R) aggressive lymphoma enrolled in the Canadian Cancer Trials Group LY.12 phase 3 trial, 59 (9.5%) had PTCL. Among these, 81% had advanced stage disease, 41% had an International Prognostic Score â¥3, and 41% were refractory to primary therapy. Within the PTCL cohort, the overall response rate after two cycles of salvage chemotherapy was 36%; no difference was observed between dexamethasone, cytarabine, cisplatin (10/30, 33%), and gemcitabine, cisplatin, dexamethasone (11/29, 38%) therapy. At one year, event-free survival (EFS) was 16% and overall survival (OS) was 28%. For PTCL patients, who received autologous stem cell transplant, two-year EFS and OS were 21% and 42%, respectively. Patients with PTCL had inferior OS (HR 0.49, p <.0001) and EFS (HR 0.53, p <.0001) compared to B-cell lymphoma. Outcomes for patients with R/R PTCL are poor with currently available therapies
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