Significant edges in the case of a non-stationary Gaussian noise

In this paper, we propose an edge detection technique based on some local smoothing of the image followed by a statistical hypothesis testing on the gradient. An edge point being defined as a zero-crossing of the Laplacian, it is said to be a significant edge point if the gradient at this point is larger than a threshold s(\eps) defined by: if the image $I$ is pure noise, then \P(\norm{\nabla I}\geq s(\eps) \bigm| \Delta I = 0) \leq\eps. In other words, a significant edge is an edge which has a very low probability to be there because of noise. We will show that the threshold s(\eps) can be explicitly computed in the case of a stationary Gaussian noise. In images we are interested in, which are obtained by tomographic reconstruction from a radiograph, this method fails since the Gaussian noise is not stationary anymore. But in this case again, we will be able to give the law of the gradient conditionally on the zero-crossing of the Laplacian, and thus compute the threshold s(\eps). We will end this paper with some experiments and compare the results with the ones obtained with some other methods of edge detection

Parameter Estimation for Quantitative EPR Spectroscopy

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Estimation of spectrum parameters for Quantitative EPR in the derivative limit

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A 1-Year Prospective French Nationwide Study of Emergency Hospital Admissions in Children and Adults with Primary Immunodeficiency

International audiencePURPOSE: Patients with primary immunodeficiency (PID) are at risk of serious complications. However, data on the incidence and causes of emergency hospital admissions are scarce. The primary objective of the present study was to describe emergency hospital admissions among patients with PID, with a view to identifying "at-risk" patient profiles.METHODS: We performed a prospective observational 12-month multicenter study in France via the CEREDIH network of regional PID reference centers from November 2010 to October 2011. All patients with PIDs requiring emergency hospital admission were included.RESULTS: A total of 200 admissions concerned 137 patients (73 adults and 64 children, 53% of whom had antibody deficiencies). Thirty admissions were reported for 16 hematopoietic stem cell transplantation recipients. When considering the 170 admissions of non-transplant patients, 149 (85%) were related to acute infections (respiratory tract infections and gastrointestinal tract infections in 72 (36%) and 34 (17%) of cases, respectively). Seventy-seven percent of the admissions occurred during winter or spring (December to May). The in-hospital mortality rate was 8.8% (12 patients); death was related to a severe infection in 11 cases (8%) and Epstein-Barr virus-induced lymphoma in 1 case. Patients with a central venous catheter (n = 19, 13.9%) were significantly more hospitalized for an infection (94.7%) than for a non-infectious reason (5.3%) (p = 0.04).CONCLUSION: Our data showed that the annual incidence of emergency hospital admission among patients with PID is 3.4%. The leading cause of emergency hospital admission was an acute infection, and having a central venous catheter was associated with a significantly greater risk of admission for an infectious episode

Outcome after failure of allogeneic hematopoietic stem cell transplantation in children with acute leukemia: a study by the société Francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC)

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