Measurement of the muon flux at the SND@LHC experiment

The Scattering and Neutrino Detector at the LHC (SND@LHC) started taking data at the beginning of Run 3 of the LHC. The experiment is designed to perform measurements with neutrinos produced in proton-proton collisions at the LHC in an energy range between 100 GeV and 1 TeV. It covers a previously unexplored pseudo-rapidity range of 7.2 < η< 8.4 . The detector is located 480 m downstream of the ATLAS interaction point in the TI18 tunnel. It comprises a veto system, a target consisting of tungsten plates interleaved with nuclear emulsion and scintillating fiber (SciFi) trackers, followed by a muon detector (UpStream, US and DownStream, DS). In this article we report the measurement of the muon flux in three subdetectors: the emulsion, the SciFi trackers and the DownStream Muon detector. The muon flux per integrated luminosity through an 18 × 18 cm 2 area in the emulsion is: 1.5±0.1(stat)×104fb/cm2. The muon flux per integrated luminosity through a 31 × 31 cm 2 area in the centre of the SciFi is: 2.06±0.01(stat)±0.12(sys)×104fb/cm2 The muon flux per integrated luminosity through a 52 × 52 cm 2 area in the centre of the downstream muon system is: 2.35±0.01(stat)±0.10(sys)×104fb/cm2 The total relative uncertainty of the measurements by the electronic detectors is 6 % for the SciFi and 4 % for the DS measurement. The Monte Carlo simulation prediction of these fluxes is 20–25 % lower than the measured values

Results and Perspectives from the First Two Years of Neutrino Physics at the LHC by the SND@LHC Experiment

After rapid approval and installation, the SND@LHC Collaboration was able to gather data successfully in 2022 and 2023. Neutrino interactions from νμs originating at the LHC IP1 were observed. Since muons constitute the major background for neutrino interactions, the muon flux entering the acceptance was also measured. To improve the rejection power of the detector and to increase the fiducial volume, a third Veto plane was recently installed. The energy resolution of the calorimeter system was measured in a test beam. This will help with the identification of νe interactions that can be used to probe charm production in the pseudo-rapidity range of SND@LHC (7.2 < η < 8.4). Events with three outgoing muons have been observed and are being studied. With no vertex in the target, these events are very likely from muon trident production in the rock before the detector. Events with a vertex in the detector could be from trident production, photon conversion, or positron annihilation. To enhance SND@LHC’s physics case, an upgrade is planned for HL-LHC that will increase the statistics and reduce the systematics. The installation of a magnet will allow the separation of νμ from ν¯μWe acknowledge the support for the construction and operation of the SND@LHC detector provided by the following funding agencies: CERN; the Bulgarian Ministry of Education and Science within the National Roadmap for Research Infrastructures 2020–2027 (object CERN); ANID—Millennium Program—ICN2019_044 (Chile); the Deutsche Forschungsgemeinschaft (DFG, ID 496466340); the Italian National Institute for Nuclear Physics (INFN); JSPS, MEXT, the Global COE program of Nagoya University, the Promotion and Mutual Aid Corporation for Private Schools of Japan for Japan; the National Research Foundation of Korea with grant numbers 2021R1A2C2011003, 2020R1A2C1099546, 2021R1F1A1061717, and 2022R1A2C100505; Fundação para a Ciência e a Tecnologia, FCT (Portugal), CERN/FIS-INS/0028/2021; the Swiss National Science Foundation (SNSF); TENMAK for Turkey (Grant No. 2022TENMAK(CERN) A5.H3.F2-1). M. Climesu, H. Lacker and R. Wanke are funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Project 496466340. We acknowledge the funding of individuals by Fundação para a Ciência e a Tecnologia, FCT (Portugal) with grant numbers CEECIND/01334/2018, CEECINST/00032/2021 and PRT/BD/153351/2021.CERNBulgarian Ministry of Education and ScienceANID—Millennium ProgramDeutsche ForschungsgemeinschaftItalian National Institute for Nuclear Physics (INFN)JSPS, MEXT, the Global COE program of Nagoya University, the Promotion and Mutual Aid Corporation for Private Schools of Japan for JapanNational Research Foundation of KoreaFundação para a Ciência e a Tecnologia, FCT (Portugal)Swiss National Science Foundation (SNSF)TENMAK for TurkeyPeer Reviewe

Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)

Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic

La renovación de la palabra en el bicentenario de la Argentina : los colores de la mirada lingüística

El libro reúne trabajos en los que se exponen resultados de investigaciones presentadas por investigadores de Argentina, Chile, Brasil, España, Italia y Alemania en el XII Congreso de la Sociedad Argentina de Lingüística (SAL), Bicentenario: la renovación de la palabra, realizado en Mendoza, Argentina, entre el 6 y el 9 de abril de 2010. Las temáticas abordadas en los 167 capítulos muestran las grandes líneas de investigación que se desarrollan fundamentalmente en nuestro país, pero también en los otros países mencionados arriba, y señalan además las áreas que recién se inician, con poca tradición en nuestro país y que deberían fomentarse. Los trabajos aquí publicados se enmarcan dentro de las siguientes disciplinas y/o campos de investigación: Fonología, Sintaxis, Semántica y Pragmática, Lingüística Cognitiva, Análisis del Discurso, Psicolingüística, Adquisición de la Lengua, Sociolingüística y Dialectología, Didáctica de la lengua, Lingüística Aplicada, Lingüística Computacional, Historia de la Lengua y la Lingüística, Lenguas Aborígenes, Filosofía del Lenguaje, Lexicología y Terminología

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P &lt; 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

DESAFIOS INTERmodais: Leituras da composição somático-digital — culturas e sonoridades

Desafios Intermodais cercam a arena da produção acadêmica. Interação e convergência são chaves mestras na inovação e distribuição do conhecimento em diversas plataformas de mídia. O ato somático de compor, considerado aqui como ação psicofísica de colher e produzir signos fora do ambiente digital se completa com a digitalização dos mesmos por meio da linguagem binária dos computadores. Alimentados por hipertextos, imagens, imagens em movimento, gestualidade, som, música, simulações em 3D, telas tácteis, múltiplos sensores interativos, e outras possíveis combinações, essas criações saem do papel e alcançam mais plataformas de mídia e, ao mesmo tempo, modificam intensamente culturas e hábitos na contemporaneidade

Introdução

Este livro reúne ensaios de pesquisadores atuantes em áreas distintas do conhecimento. O presente volume volta-se para as atuais mudanças culturais provocadas por inovações tecnológicas e as consequentes revisões de padrões e formas de produzir e organizar o conhecimento humano. É também o terceiro volume de uma série de cadernos do grupo de pesquisa ECUS (Espetáculos Culturais e Sociedade) que, desde 2009, seleciona e organiza os diversos ensaios por uma perspectiva interdisciplinar e ao mesmo tempo experimental. O presente experimento surge do diálogo entre os grupos de pesquisa ECUS e GREC (Grupo de Estudos sobre Cibermuseus), cujos membros se concentram em decifrar a complexidade simbólica de criações e produções na sociedade e no ciberespaço — sua codificação e decodificação no mundo contemporâneo