Online Photography Toolkits: Digital Approaches to Practical Delivery.

This paper draws on pedagogical research, and in particular it focuses on a research project developed by the Photography team at the University of Northampton: Leet, S., Sherwood, T., Murphy, A., Kalpaxi, E., Franchi, E., Wardle, C., Lowe, C., Smith, J. A. (2016-2017) ‘Online Photography Toolkits: Digital Approaches to Practical Delivery’, funded by the Institute of Learning and Teaching (ILT) of the University of Northampton. The Photography team at the University of Northampton created a series of digital toolkits to enable students to access information ‘on demand’ through a number of platforms and mobile devices. The development of effective digital resources to facilitate independent asynchronous skills-oriented learning (that commonly involves a hands-on approach) has been acknowledged as an essential need and a challenge in previous Photography CAleRO workshops. The development of these resources also provides potential for greater openness, in terms of sharing resources among departments and the wider public, for educational, pedagogic, and marketing purposes. In line with the University’s Waterside move in 2018, the toolkits will provide a digital resource to aid blended and flipped learning within Photography undergraduate programmes – a way to provide access to essential technical information and support beyond the confines of conventional teaching environments. This project would be appropriate for first year students needing additional support, as well as second year and Top-Up students requiring a refresher of practical skills. Traditional teaching approaches can pose barriers to a number of students, and offer only a finite duration of contact through practical delivery. It is hoped that the implementation of online toolkits will promote inclusion and lead to improved engagement and achievement for all learners, including the significant number in our cohorts who have learning differences and physical disabilities (e.g. deafness)

Flamingo Vol. I N 3

Voo-Doo. Untitled. Prose. 1. Widow. Untitled. Prose. 1. Tiger. Untitled. Prose. 1. Purple Cow. Untitled. Prose. 1. Anonymous. Untitled. Prose. 1. Life. Untitled. Prose. 2. Yale Record. Untitled. Prose. 2. Voo-Doo. Untitled. Prose. 2. Sour Owl. Untitled. Prose. 2. Puppet. Untitled. Prose. 2. Sun Dial. Untitled. Prose. 2. Anonymous. Untitled. Prose. 2. Nottingham, Ruth. Teddy . Prose. 5. Grogan. Untitled. Picture. 7. Anonymous. Untitled. Prose. 7. Anonymous. An Easy One . Prose. 7. Anonymous. How Terrible! Prose. 7. Anonymous. Untitled. Prose. 7. Anonymous. Untitled. Poem. 7. F.H.G. Untitled. Picture. 7. Wood, J.E.F. When mother Went to College . Prose. 8. E.D.T. Chicago Corn Exchange . Poem. 8. Anonymous. Untitled. Prose. 8. Anonymous. Untitled. Poem. 8. Anonymous. All But . Prose. 8. R.D.B. Roscoe to The Rescue . Prose. 9. Leet, L.D. On The Efficacy of Dreams . Prose. 10. Orange Ade. The Fable of the Coffin Nailer . Prose. 11. Orange Ade. Time Wasted . Prose. 11. Orange Ade. The Americanized Boy . Prose. 11. Orange Ade. Anything to Oblige . Prose. 11. Orange Ade. Tit For Tat . Prose. 11. Orange Ade. Good Alibi . Prose. 11. Orange Ade. Untitled. Prose. 11. Grogan. Untitled. Picture. 11. Lusk, R.G. On The Absurdity of Catching Fish When A-Fishing . Prose. 12. Anonymous. Co-eds and Plain Eds in 1950 . Picture. 13. Potter, W.M. Letters of A Japanese Sandman . Prose. 13. Anonymous. Ex Facultate . Prose. 13. Anonymous. Untitled. Prose. 13. R.J.S. An Uplifting Influence . Picture. 13. Anonymous. Consider the Luxite Girl . Poem. 14. Anonymous. Shades of Orpheus . Poem. 14. Anonymous. With The Gospel Team . Poem. 14. Anonymous. Untitled. Prose. 14. Anonymous. Untitled. Poem. 14. Anonymous. A Dirty Trick . Prose. 14. Taylor, Elsie D. Vestigial Customs . Prose. 15. Anonymous. Untitled. Prose. 16. Anonymous. A New version of Anthropology . Prose. 18. Anonymous. A New version of Anthropology . Picture. 18. Anonymous. Untitled. Prose. 18. Funk, Dorothy K. Untitled. Picture. 18. Anonymous. A Deep one . Prose. 18. Anonymous. Take His Name . Prose. 18. Olney, Clarke. The Evolution of An Intellectual . Prose. 19. Anonymous. Untitled. Prose. 19. Anonymous. Untitled. Prose. 20. W.A.W. On Getting Up For Breakfast . Prose. 20. McCann. Untitled. Picture. 21. Anonymous. Untitled. Prose. 21. Anonymous. S.S.S. . Prose. 21. Anonymous. The Judge Disagreed . Prose. 21. Anonymous. The Modern Woman . Prose. 21. Anonymous. Denison Slang in Japan . Prose. 22. Anonymous. Being Specific . Prose. 22. Anonymous. Then The Fun Began . Prose. 22. Anonymous. Then The Fun Began . Prose. 22. Anonymous. Chess Nuts . Poem. 22. Anonymous. Chess Nuts . Picture. 22. Funk, Dorothy K. Untitled. Picture. 22. Anonymous. Untitled. Prose. 22. Reel, Virginia. Untitled. Prose. 22. Anonymous. Untitled. Prose. 23. Anonymous. Take This to Heart . Prose. 23. Anonymous. Stepping Out . Picture. 23. Olney, Clarke. Untitled. Picture. 23. Anonymous. To Lalage . Prose. 23. Anonymous. Untitled. Poem. 24. Anonymous. Description of the Day . Prose. 25. Anonymous. Untitled. Prose. 25. Voo-Doo. Good Bizziness . Prose. 26. Anonymous. Fore! . Prose. 26. Anonymous. Untitled. Prose. 26. Brelsford, Ernest C. Souveniring . Prose. 27. Anonymous. Untitled. Prose. 30. Burr. Sweet Dreams . Prose. 30. Jester. Untitled. Prose. 30. Judge. Untitled. Prose. 30. Goblin. Untitled. Prose. 30. Cracker. Sanitation . Poem. 32. Anonymous. Untitled. Prose. 32. Jester. Untitled. Prose. 32. Goblin. Untitled. Prose. 32. Record. Untitled. Prose. 32. Linotype. Untitled. Prose. 32. Holt, Kilburn. The Schemer\u27s Lament . Poem. 7. Owen, Ernest t. Mother . Poem. 3. Owen, Ernest T. To--- . Poem. 24

An Instrument to Measure Skeletal Burden and Predict Functional Outcome in Fibrous Dysplasia of Bone

Abstract An instrument to measure skeletal burden in fibrous dysplasia was developed. Biological and clinical relevance was shown by correlating skeletal burden scores with bone markers, quality of life, and ambulatory status. Childhood scores predict adult ambulatory status, and scores were unaffected when bone markers decreased with bisphosphonate treatment or aging. Introduction: Fibrous dysplasia (FD) is a skeletal disease with a broad clinical expression. There is no objective method to assess the extent of skeletal involvement or predict outcome. We developed an instrument to measure skeletal burden that correlates with physical function, health-related quality of life (HRQL), and ambulatory status. Materials and Methods: Seventy-nine patients with FD underwent bone scintigraphy. The skeletal burden score was derived from a weighted score based on the regional measurement using bone scintigraphy to estimate the amount of FD in anatomical segments. Six readers scored 20 scans twice to determine the inter- and intrareader agreement. To assess biological significance, scores were correlated with bone markers. To assess functional outcome, scores on the SF-36 (adults) or CHQ-PF50 (children) were correlated with skeletal burden scores. In a group of patients who had bone scans as children and adults (n = 6), the ability to predict ambulatory status was tested. Skeletal burden scores were assessed in patients before and after treatment with pamidronate (n = 5). Results: The inter- and intrareader agreement of burden scores were r = 0.96, and 0.98, respectively (p < 0.001 for both). The scores correlated with markers of bone metabolism and HRQL (Spearman rho, 0.54-0.67 p < 0.001 and −0.43, p = 0.001, respectively). The mean score of patients who ambulated unassisted was significantly lower than those requiring assistance (p < 0.001 unassisted versus crutch and/or wheelchair). In unassisted ambulators, younger patients had higher scores, suggesting high childhood scores may predict adulthood impairment. In six patients with childhood and adulthood scans, childhood scores >30 predicted assisted ambulation in adulthood. There was a negative correlation between bone markers and age (Spearman rho, −0.42 to −0.70; p < 0.001), but not age and skeletal burden score. Pamidronate treatment decreased serum alkaline phosphatase but had no effect on the skeletal burden score. Conclusions: This is a validated and reliable instrument for the measurement of skeletal burden of FD and is able to predict functional outcome

EXPRES I. HD~3651 an Ideal RV Benchmark

The next generation of exoplanet-hunting spectrographs should deliver up to an order of magnitude improvement in radial velocity precision over the standard 1 m/s state of the art. This advance is critical for enabling the detection of Earth-mass planets around Sun-like stars. New calibration techniques such as laser frequency combs and stabilized etalons ensure that the instrumental stability is well characterized. However, additional sources of error include stellar noise, undetected short-period planets, and telluric contamination. To understand and ultimately mitigate error sources, the contributing terms in the error budget must be isolated to the greatest extent possible. Here, we introduce a new high cadence radial velocity program, the EXPRES 100 Earths program, which aims to identify rocky planets around bright, nearby G and K dwarfs. We also present a benchmark case: the 62-d orbit of a Saturn-mass planet orbiting the chromospherically quiet star, HD 3651. The combination of high eccentricity (0.6) and a moderately long orbital period, ensures significant dynamical clearing of any inner planets. Our Keplerian model for this planetary orbit has a residual RMS of 58 cm/s over a $\sim 6$ month time baseline. By eliminating significant contributors to the radial velocity error budget, HD 3651 serves as a standard for evaluating the long term precision of extreme precision radial velocity (EPRV) programs.Comment: 11 pages, 6 figures, accepted for publication in Astronomical Journa

Proximal femoral resection arthroplasty for patients with cerebral palsy and dislocated hips: 20 patients followed for 1–6 years

Background and purpose Chronic hip dislocation in non-ambulatory individuals with cerebral palsy (CP) can lead to severe problems, of which pain is often the most severe. We studied the outcome of proximal femoral resection, especially regarding pain, sitting balance, perineal care, and patient satisfaction

Global Search for New Physics with 2.0/fb at CDF

Data collected in Run II of the Fermilab Tevatron are searched for indications of new electroweak-scale physics. Rather than focusing on particular new physics scenarios, CDF data are analyzed for discrepancies with the standard model prediction. A model-independent approach (Vista) considers gross features of the data, and is sensitive to new large cross-section physics. Further sensitivity to new physics is provided by two additional algorithms: a Bump Hunter searches invariant mass distributions for "bumps" that could indicate resonant production of new particles; and the Sleuth procedure scans for data excesses at large summed transverse momentum. This combined global search for new physics in 2.0/fb of ppbar collisions at sqrt(s)=1.96 TeV reveals no indication of physics beyond the standard model.Comment: 8 pages, 7 figures. Final version which appeared in Physical Review D Rapid Communication

Gendered Discourse in the Political Behavior of Adolescents

The roots of adult civic and political participation originate in pre-adult experiences (Verba et al. 1995) and high school extracurricular activities offer students opportunities to develop interpersonal and leadership skills. In this research, we ask whether adolescents also learn gendered norms of political discourse through extracurricular activities. This project assessed gender differences in participation at the 1999 Model United Nations of the Southwest (MUNSW) at the University of Oklahoma. Important differences in participation were observed in the number and character of speaking turns taken by male and female delegates. We find that contextual factors, such as the sex of the committee chair, the issue areas addressed by the committee, and the timing of the session in the conference significantly influence who participates in the discourse, but the percentage of female participants surprisingly does not. The character of the political discourse suggests norms dominated by masculinity.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

McCune-Albright syndrome

McCune-Albright syndrome (MAS) is classically defined by the clinical triad of fibrous dysplasia of bone (FD), café-au-lait skin spots, and precocious puberty (PP). It is a rare disease with estimated prevalence between 1/100,000 and 1/1,000,000. FD can involve a single or multiple skeletal sites and presents with a limp and/or pain, and, occasionally, a pathologic fracture. Scoliosis is common and may be progressive. In addition to PP (vaginal bleeding or spotting and development of breast tissue in girls, testicular and penile enlargement and precocious sexual behavior in boys), other hyperfunctioning endocrinopathies may be involved including hyperthyroidism, growth hormone excess, Cushing syndrome, and renal phosphate wasting. Café-au-lait spots usually appear in the neonatal period, but it is most often PP or FD that brings the child to medical attention. Renal involvement is seen in approximately 50% of the patients with MAS. The disease results from somatic mutations of the GNAS gene, specifically mutations in the cAMP regulating protein, Gs alpha. The extent of the disease is determined by the proliferation, migration and survival of the cell in which the mutation spontaneously occurs during embryonic development. Diagnosis of MAS is usually established on clinical grounds. Plain radiographs are often sufficient to make the diagnosis of FD and biopsy of FD lesions can confirm the diagnosis. The evaluation of patients with MAS should be guided by knowledge of the spectrum of tissues that may be involved, with specific testing for each. Genetic testing is possible, but is not routinely available. Genetic counseling, however, should be offered. Differential diagnoses include neurofibromatosis, osteofibrous dysplasia, non-ossifying fibromas, idiopathic central precocious puberty, and ovarian neoplasm. Treatment is dictated by the tissues affected, and the extent to which they are affected. Generally, some form of surgical intervention is recommended. Bisphosphonates are frequently used in the treatment of FD. Strengthening exercises are recommended to help maintaining the musculature around the FD bone and minimize the risk for fracture. Treatment of all endocrinopathies is required. Malignancies associated with MAS are distinctly rare occurrences. Malignant transformation of FD lesions occurs in probably less than 1% of the cases of MAS

An Extreme Precision Radial Velocity Pipeline: First Radial Velocities from EXPRES

The EXtreme PREcision Spectrograph (EXPRES) is an environmentally stabilized, fiber-fed, $R=137,500$, optical spectrograph. It was recently commissioned at the 4.3-m Lowell Discovery Telescope (LDT) near Flagstaff, Arizona. The spectrograph was designed with a target radial-velocity (RV) precision of 30$\mathrm{~cm~s^{-1}}$. In addition to instrumental innovations, the EXPRES pipeline, presented here, is the first for an on-sky, optical, fiber-fed spectrograph to employ many novel techniques---including an "extended flat" fiber used for wavelength-dependent quantum efficiency characterization of the CCD, a flat-relative optimal extraction algorithm, chromatic barycentric corrections, chromatic calibration offsets, and an ultra-precise laser frequency comb for wavelength calibration. We describe the reduction, calibration, and radial-velocity analysis pipeline used for EXPRES and present an example of our current sub-meter-per-second RV measurement precision, which reaches a formal, single-measurement error of 0.3$\mathrm{~m~s^{-1}}$ for an observation with a per-pixel signal-to-noise ratio of 250. These velocities yield an orbital solution on the known exoplanet host 51 Peg that matches literature values with a residual RMS of 0.895$\mathrm{~m~s^{-1}}$

Pancreatic enzyme replacement therapy in patients with pancreatic cancer: A national prospective study

Objective: UK national guidelines recommend pancreatic enzyme replacement therapy (PERT) in pancreatic cancer. Over 80% of pancreatic cancers are unresectable and managed in non-surgical units. The aim was to assess variation in PERT prescribing, determine factors associated with its use and identify potential actions to improve prescription rates. Design: RICOCHET was a national prospective audit of malignant pancreatic, peri-ampullary lesions or malignant biliary obstruction between April and August 2018. This analysis focuses on pancreatic cancer patients and is reported to STROBE guidelines. Multivariable regression analysis was undertaken to assess factors associated with PERT prescribing. Results: Rates of PERT prescribing varied among the 1350 patients included. 74.4% of patients with potentially resectable disease were prescribed PERT compared to 45.3% with unresectable disease. PERT prescription varied across surgical hospitals but high prescribing rates did not disseminate out to the respective referring network. PERT prescription appeared to be related to the treatment aim for the patient and the amount of clinician contact a patient has. PERT prescription in potentially resectable patients was positively associated with dietitian referral (p = 0.001) and management at hepaticopancreaticobiliary (p = 0.049) or pancreatic unit (p = 0.009). Prescription in unresectable patients also had a negative association with Charlson comorbidity score 5–7 (p = 0.045) or >7 (p = 0.010) and a positive association with clinical nurse specialist review (p = 0.028). Conclusion: Despite national guidance, wide variation and under-treatment with PERT exists. Given that most patients with pancreatic cancer have unresectable disease and are treated in non-surgical hospitals, where prescribing is lowest, strategies to disseminate best practice and overcome barriers to prescribing are urgently required