187 research outputs found
Distinct crustal structure of the North American Midcontinent Rift from P wave receiver functions
Eighty-two broadband seismic stations of the Superior Province Rifting Earthscope Experiment (SPREE) collected 2.5 years of continuous seismic data in the area of the high gravity anomaly associated with the Midcontinent Rift (MCR). Over 100 high-quality teleseismic earthquakes were used for crustal P wave receiver function analysis. Our analysis reveals that the base of the sedimentary layer is shallow outside the MCR, thickens near the flanks where gravity anomalies are low, and shallows again in the MCR's center where the gravity anomalies peak. This pattern is similar to that found from local geophysical studies and is consistent with reverse faulting having accompanied the cessation of rifting at 1.1 Ga. Intermittent intracrustal boundaries imaged by our analysis might represent the bottom of the MCR's mostly buried dense volcanic layers. Outside the MCR, the Moho is strong, sharp, and relatively flat, both beneath the Archean Superior Province and the Proterozoic terranes to its south. Inside the MCR, two weaker candidate Mohos are found at depths up to 25 km apart in the rift's center. The intermediate layer between these discontinuities tapers toward the edges of the MCR. The presence of this transitional layer is remarkably consistent along the strike of the MCR, including beneath its jog in southern Minnesota, near the Belle Plaine Fault. We interpret these results as evidence for extensive underplating as a defining characteristic of the rift, which remains continuous along the Minnesota jog, where due to its orientation, it is minimally affected by the reverse faulting that characterizes the NNE striking parts of the rift
Long term productivity and collaboration in information science
This is an accepted manuscript of an article published by Springer in Scientometrics on 02/07/2016, available online: https://doi.org/10.1007/s11192-016-2061-8
The accepted version of the publication may differ from the final published version.Funding bodies have tended to encourage collaborative research because it is generally more highly cited than sole author research. But higher mean citation for collaborative articles does not imply collaborative researchers are in general more research productive. This article assesses the extent to which research productivity varies with the number of collaborative partners for long term researchers within three Web of Science subject areas: Information Science & Library Science, Communication and Medical Informatics. When using the whole number counting system, researchers who worked in groups of 2 or 3 were generally the most productive, in terms of producing the most papers and citations. However, when using fractional counting, researchers who worked in groups of 1 or 2 were generally the most productive. The findings need to be interpreted cautiously, however, because authors that produce few academic articles within a field may publish in other fields or leave academia and contribute to society in other ways
Green function techniques in the treatment of quantum transport at the molecular scale
The theoretical investigation of charge (and spin) transport at nanometer
length scales requires the use of advanced and powerful techniques able to deal
with the dynamical properties of the relevant physical systems, to explicitly
include out-of-equilibrium situations typical for electrical/heat transport as
well as to take into account interaction effects in a systematic way.
Equilibrium Green function techniques and their extension to non-equilibrium
situations via the Keldysh formalism build one of the pillars of current
state-of-the-art approaches to quantum transport which have been implemented in
both model Hamiltonian formulations and first-principle methodologies. We offer
a tutorial overview of the applications of Green functions to deal with some
fundamental aspects of charge transport at the nanoscale, mainly focusing on
applications to model Hamiltonian formulations.Comment: Tutorial review, LaTeX, 129 pages, 41 figures, 300 references,
submitted to Springer series "Lecture Notes in Physics
Velocity–conductivity relationships for mantle mineral assemblages in Archean cratonic lithosphere based on a review of laboratory data and Hashin–Shtrikman extremal bounds
Author Posting. © Elsevier B.V., 2009. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Lithos 109 (2009): 131-143, doi:10.1016/j.lithos.2008.10.014.Can mineral physics and mixing theories explain field observations of seismic velocity
and electrical conductivity, and is there an advantage to combining seismological and
electromagnetic techniques? These two questions are at the heart of this paper. Using
phenomologically-derived state equations for individual minerals coupled with multi-phase,
Hashin-Shtrikman extremal-bound theory we derive the likely shear and compressional
velocities and electrical conductivity at three depths, 100 km, 150 km and 200 km, beneath
the central part of the Slave craton and beneath the Kimberley region of the Kaapvaal craton
based on known petrologically-observed mineral abundances and magnesium numbers,
combined with estimates of temperatures and pressures. We demonstrate that there are
measurable differences between the physical properties of the two lithospheres for the upper
depths, primarily due to the different ambient temperature, but that differences in velocity are
negligibly small at 200 km. We also show that there is an advantage to combining seismic and
electromagnetic data, given that conductivity is exponentially dependent on temperature
whereas the shear and bulk moduli have only a linear dependence in cratonic lithospheric
rocks.
Focussing on a known discontinuity between harzburgite-dominated and lherzolitic
mantle in the Slave craton at a depth of about 160 km, we demonstrate that the amplitude of
compressional (P) wave to shear (S) wave conversions would be very weak, and so
explanations for the seismological (receiver function) observations must either appeal to
effects we have not considered (perhaps anisotropy), or imply that the laboratory data require
further refinement
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Fifty years of research on the Madden-Julian Oscillation: recent progress, challenges and perspectives
Since its discovery in the early 1970s, the crucial role of the Madden-Julian Oscillation (MJO) in the global hydrological cycle and its tremendous influence of high-impact climate and weather extremes have been well recognised. The MJO also serves as a primary source of predictability for global Earth system variability on subseasonal time scales. The MJO remains poorly represeted in our state-of-the-art climate and weather forecasting models, however. Moreover, despite the advances made in recent decades, theories for the MJO still disagree at a fundamental level. The problems of understanding and modeling the MJO have attracted significant interest from the research community. As part of the AGU's Centennial collection, this article provides a review of recent progress, particularly over the last decade, in observational, modeling and theoretical study of the MJO. A brief outlook for near-future MJO research directions is also provided
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis
IMPORTANCE:
Amyloid-β positron emission tomography (PET) imaging allows in vivo detection of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its diagnostic utility is still unclear because amyloid plaques also occur in patients with non-AD dementia.
OBJECTIVE:
To use individual participant data meta-analysis to estimate the prevalence of amyloid positivity on PET in a wide variety of dementia syndromes.
DATA SOURCES:
The MEDLINE and Web of Science databases were searched from January 2004 to April 2015 for amyloid PET studies.
STUDY SELECTION:
Case reports and studies on neurological or psychiatric diseases other than dementia were excluded. Corresponding authors of eligible cohorts were invited to provide individual participant data.
DATA EXTRACTION AND SYNTHESIS:
Data were provided for 1359 participants with clinically diagnosed AD and 538 participants with non-AD dementia. The reference groups were 1849 healthy control participants (based on amyloid PET) and an independent sample of 1369 AD participants (based on autopsy).
MAIN OUTCOMES AND MEASURES:
Estimated prevalence of positive amyloid PET scans according to diagnosis, age, and apolipoprotein E (APOE) ε4 status, using the generalized estimating equations method.
RESULTS:
The likelihood of amyloid positivity was associated with age and APOE ε4 status. In AD dementia, the prevalence of amyloid positivity decreased from age 50 to 90 years in APOE ε4 noncarriers (86% [95% CI, 73%-94%] at 50 years to 68% [95% CI, 57%-77%] at 90 years; n = 377) and to a lesser degree in APOE ε4 carriers (97% [95% CI, 92%-99%] at 50 years to 90% [95% CI, 83%-94%] at 90 years; n = 593; P < .01). Similar associations of age and APOE ε4 with amyloid positivity were observed in participants with AD dementia at autopsy. In most non-AD dementias, amyloid positivity increased with both age (from 60 to 80 years) and APOE ε4 carriership (dementia with Lewy bodies: carriers [n = 16], 63% [95% CI, 48%-80%] at 60 years to 83% [95% CI, 67%-92%] at 80 years; noncarriers [n = 18], 29% [95% CI, 15%-50%] at 60 years to 54% [95% CI, 30%-77%] at 80 years; frontotemporal dementia: carriers [n = 48], 19% [95% CI, 12%-28%] at 60 years to 43% [95% CI, 35%-50%] at 80 years; noncarriers [n = 160], 5% [95% CI, 3%-8%] at 60 years to 14% [95% CI, 11%-18%] at 80 years; vascular dementia: carriers [n = 30], 25% [95% CI, 9%-52%] at 60 years to 64% [95% CI, 49%-77%] at 80 years; noncarriers [n = 77], 7% [95% CI, 3%-18%] at 60 years to 29% [95% CI, 17%-43%] at 80 years.
CONCLUSIONS AND RELEVANCE:
Among participants with dementia, the prevalence of amyloid positivity was associated with clinical diagnosis, age, and APOE genotype. These findings indicate the potential clinical utility of amyloid imaging for differential diagnosis in early-onset dementia and to support the clinical diagnosis of participants with AD dementia and noncarrier APOE ε4 status who are older than 70 years
Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process
Exercise in young adults has been consistently shown to improve various aspects of physiological and psychological health but we are now realising the potential benefits of exercise with advancing age. Specifically, exercise improves cardiovascular, musculoskeletal, and metabolic health through reductions in oxidative stress, chronic low-grade inflammation and modulating cellular processes within a variety of tissues. In this this chapter we will discuss the effects of acute and chronic exercise on these processes and conditions in an ageing population, and how physical activity affects our vasculature, skeletal muscle function, our immune system, and cardiometabolic risk in older adults
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