Metamorphosis-Induced Changes in the Coupling of Spinal Thoraco-Lumbar Motor Outputs During Swimming in Xenopus laevis

International audienceBeyeler A, Métais C, Combes D, Simmers J, Le Ray D. Metamorphosis induced changes in the coupling of spinal thoraco-lumbar motor outputs during swimming in Xenopus laevis. Anuran metamorphosis includes a complete remodeling of the animal's biomechanical apparatus, requiring a corresponding functional reorganization of underlying central neural circuitry. This involves changes that must occur in the coordination between the motor outputs of different spinal segments to harmonize locomotor and postural functions as the limbs grow and the tail regresses. In premetamorphic Xenopus laevis tadpoles, axial motor output drives rostrocaudally propagating segmental myotomal contractions that generate propulsive body undulations. During metamorphosis, the anterior axial musculature of the tadpole progressively evolves into dorsal muscles in the postmetamorphic froglet in which some of these back muscles lose their implicit locomotor function to serve exclusively in postural control in the adult. To understand how locomotor and postural systems interact during locomotion in juvenile Xenopus, we have investigated the coordination between postural back and hindlimb muscle activity during free forward swimming. Axial/ dorsal muscles, which contract in bilateral alternation during undulatory swimming in premetamorphic tadpoles, change their left-right coordination to become activated in phase with bilaterally synchronous hindlimb extensions in locomoting juveniles. Based on in vitro electrophysiologi-cal experiments as well as specific spinal lesions in vivo, a spinal cord region was delimited in which propriospinal interactions are directly responsible for the coordination between leg and back muscle contractions. Our findings therefore indicate that dynamic postural adjustments during adult Xenopus locomotion are mediated by local intraspinal pathways through which the lumbar generator for hindlimb propulsive kicking provides caudorostral commands to thoracic spinal circuitry controlling the dorsal trunk musculature

An Early Cretaceous vertebrate assemblage from the Cabao Formation of NW Libya

Fossil vertebrates from the Cabao Formation discovered in the area of Nalut in northwestern Libya include the hybodont shark Priohybodus, the crocodilian Sarcosuchus, an abelisaurid, a baryonichine spinosaurid and a large sauropod with spatulate teeth. The Cabao Formation may be Hauterivian to Barremian in age, although an earlier Berriasian to Valanginian age cannot be excluded. Its dinosaur assemblage is reminiscent of that of the El Rhaz and Tiouraren formations of Niger and strongly differs from both the Cenomanian assemblages of Morocco and Egypt and the Late Aptian to Albian fauna of Tunisia. Fossil vertebrates may be an important tool to establish the stratigraphical framework of the poorly dated Early Cretaceous continental deposits of Afric

Identifying Right-Wing Extremism in German Twitter Profiles: a Classification Approach

Hartung M, Klinger R, Schmidtke F, Vogel L. Identifying Right-Wing Extremism in German Twitter Profiles: a Classification Approach. In: Frascinar F, Ittoo A, Nguyen LM, Métais E, eds. Natural Language Processing and Information Systems: 22nd International Conference on Applications of Natural Language to Information Systems (NLDB 2017). Lecture Notes in Computer Science. Vol 10260. Springer International Publishing; 2017: 320-325.Social media platforms are used by an increasing number of extremist political actors for mobilization, recruiting or radicalization purposes. We propose a machine learning approach to support manual monitoring aiming at identifying right-wing extremist content in German Twitter profiles. We frame the task as profile classification, based on textual cues, traits of emotionality in language use, and linguistic patterns. A quantitative evaluation reveals a limited precision of 25 % with a close-to-perfect recall of 95 %. This leads to a considerable reduction of the workload of human analysts in detecting right-wing extremist users

Downgraded curriculum? An analysis of knowledge in new curricula in Scotland and New Zealand

The development, since 2000, of new National Curricula across the Anglophone world signals a number of policy trends, including: a move from the explicit specification of content towards a more generic, skills-based approach; a greater emphasis on the centrality of the learner; and [ostensibly] greater autonomy for teachers in developing the curriculum in school. These policy shifts have attracted some criticism, especially from social realist writers, who claim that the new curricula downgrade knowledge. This paper offers a contribution to this debate; an empirically-based analysis of two new curricula, New Zealand’s Curriculum Framework and Scotland’s Curriculum for Excellence. We conclude that, while these curricula continue to accord considerable importance to knowledge in their statements of policy intent, the social realist critique is at least partially justified, since both curricula are characterised by a lack of coherence and mixed messages about the place of knowledge

INCEFA-PLUS Findings on Environmental Fatigue

INCEFA-PLUS is a five year project supported by the European Commission HORIZON2020 programme. The project concluded in October 2020. 16 organisations from across Europe have combined forces to deliver new experimental data which is being used to develop improved guidelines for assessment of environmental fatigue damage to ensure safe operation of nuclear power plants. Within INCEFA-PLUS, the effects of mean strain and stress, hold time, strain amplitude and surface finish on fatigue endurance of austenitic stainless steels in light water reactor environments have been studied experimentally. This document constitutes a Reference Book compiling the research developed within the INCEFA-PLUS Project. It provides a comprehensive overview of the tasks performed, and it also presents the background and the assumptions taken to develop the INCEFA-PLUS experimental and analytical works. It compiles and orders documents and contributions from INCEFA-PLUS partners.This project has received funding from the Euratom research and training program 2014-2018 under grant agreement No 662320

Strong and weak constraint variational assimilations for reduced order fluid flow modeling

International audienceIn this work we propose and evaluate two variational data assimilation techniques for the estimation of low order surrogate experimental dynamical models for fluid flows. Both methods are built from optimal control recipes and rely on proper orthogonal decomposition and a Galerkin projection of the Navier Stokes equation. The techniques proposed di er in the control variables they involve. The first one introduces a weak dynamical model defined only up to an additional uncertainty time-dependent function whereas the second one, handles a strong dynamical constraint in which the dynamical system's coe cients constitute the control variables. Both choices correspond to di erent approximations of the relation between the reduced basis on which is expressed the motion field and the basis components that have been neglected in the reduced order model construction. The techniques have been assessed on numerical data and for real experimental conditions with noisy Image Velocimetry data