Verification of a two-phase flow code based on an homogeneous model

International audienceWe present some verification test cases applied to a code developed at EDF R&D for the simulation of two-phase flows with mass transfer. The aim of this code is to allow the simulation of a wide range of industrial situations by considering all the thermodynamic disequilibria between the phases-pressure, temperature and chemical potential-and by assuming the kinematic equilibrium-a single velocity for both phases. The underlying homogeneous model [1, 13] is based on the Euler system of equations supplemented by a complex pressure law describing the behaviour of the mixture of the two phases. Different first-order schemes are compared on the basis of two analytical solutions: a classical Riemann problem and a steady-state heated pipe test

Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System.

International audienceHuman coronaviruses (HCoV) are respiratory pathogens that may be associated with the development of neurological diseases, in view of their neuroinvasive and neurotropic properties. The viral spike (S) glycoprotein is a major virulence factor for several coronavirus species, including the OC43 strain of HCoV (HCoV-OC43). In an attempt to study the role of this protein in virus spread within the central nervous system (CNS) and neurovirulence, as well as to identify amino acid residues important for such functions, we compared the sequence of the S gene found in the laboratory reference strain HCoV-OC43 ATCC VR-759 to S sequences of viruses detected in clinical isolates from the human respiratory tract. We identified one predominant mutation at amino acid 758 (from RRSR↓ G758 to RRSR↓R758), which introduces a putative furin-like cleavage (↓) site. Using a molecular cDNA infectious clone to generate a corresponding recombinant virus, we show for the first time that such point mutation in the HCoV-OC43 S glycoprotein creates a functional cleavage site between the S1 and S2 portions of the S protein. While the corresponding recombinant virus retained its neuroinvasive properties, this mutation led to decreased neurovirulence while potentially modifying the mode of virus spread, likely leading to a limited dissemination within the CNS. Taken together, these results are consistent with the adaptation of HCoV-OC43 to the CNS environment, resulting from the selection of quasi-species harboring mutations that lead to amino acid changes in viral genes, like the S gene in HCoV-OC43, which may contribute to a more efficient establishment of a less pathogenic but persistent CNS infection. This adaptative mechanism could potentially be associated with human encephalitis or other neurological degenerative pathologies

A general model for the identification of specific PAHs in the far-IR

Context. In the framework of the interstellar PAH hypothesis, far-IR skeletal bands are expected to be a fingerprint of single species in this class. Aims. A detailed model of the photophysics of interstellar PAHs is required for such single-molecule identification of their far-IR features in the presently available Infrared Space Observatory data and in those of the forthcoming Herschel Space Observatory mission. Methods. We modelled the detailed photophysics of a vast sample of species in different radiation fields, using a compendium of Monte-Carlo techniques and quantum-chemical calculations. This enabled us to validate the use of purely theoretical data and assess the expected accuracy and reliability of the resulting synthetic far-IR emission spectra. Results. We produce positions and intensities of the expected far-IR features which ought to be emitted by each species in the sample in the considered radiation fields. A composite emission spectrum for our sample is computed for one of the most favourable sources for detection, namely the Red Rectangle nebula. The resulting spectrum is compared with the estimated dust emission in the same source, to assess the dependence of detectability on key molecular parameters. Conclusions. Identifying specific PAHs from their far-IR features is going to be a difficult feat in general, still it may well be possible under favourable conditions.Comment: 14 pages, 9 figures + 18 pages of online appendix. Accepted for publication in A&A (09/06/2006

Hubble Space Telescope Survey of Interstellar ^12CO/^13CO in the Solar Neighborhood

We examine 20 diffuse and translucent Galactic sight lines and extract the column densities of the ^12CO and ^13CO isotopologues from their ultraviolet A--X absorption bands detected in archival Space Telescope Imaging Spectrograph data with lambda/Deltalambda geq 46,000. Five more targets with Goddard High-Resolution Spectrograph data are added to the sample that more than doubles the number of sight lines with published Hubble Space Telescope observations of ^13CO. Most sight lines have 12-to-13 isotopic ratios that are not significantly different from the local value of 70 for ^12C/^13C, which is based on mm-wave observations of rotational lines in emission from CO and H_2CO inside dense molecular clouds, as well as on results from optical measurements of CH^+. Five of the 25 sight lines are found to be fractionated toward lower 12-to-13 values, while three sight lines in the sample are fractionated toward higher ratios, signaling the predominance of either isotopic charge exchange or selective photodissociation, respectively. There are no obvious trends of the ^12CO-to-^13CO ratio with physical conditions such as gas temperature or density, yet ^12CO/^13CO does vary in a complicated manner with the column density of either CO isotopologue, owing to varying levels of competition between isotopic charge exchange and selective photodissociation in the fractionation of CO. Finally, rotational temperatures of H_2 show that all sight lines with detected amounts of ^13CO pass through gas that is on average colder by 20 K than the gas without ^13CO. This colder gas is also sampled by CN and C_2 molecules, the latter indicating gas kinetic temperatures of only 28 K, enough to facilitate an efficient charge exchange reaction that lowers the value of ^12CO/^13CO.Comment: 1-column emulateapj, 23 pages, 9 figure

A Multi-Wavelength Infrared Study of NGC 891

We present a multi-wavlength infrared study of the nearby, edge-on, spiral galaxy NGC 891. We have examined 20 independent, spatially resolved IR images of this galaxy, 14 of which are newly reduced and/or previously unpublished images. These images span a wavelength regime from 1.2 microns in which the emission is dominated by cool stars, through the MIR, in which emission is dominated by PAHs, to 850 microns, in which emission is dominated by cold dust in thermal equilibrium with the radiation field. The changing morphology of the galaxy with wavelength illustrates the changing dominant components. We detect extra-planar dust emission in this galaxy, consistent with previously published results, but now show that PAH emission is also in the halo, to a vertical distance of z >= 2.5 kpc. We compare the vertical extents of various components and find that the PAHs (from 7.7 and 8 micron data) and warm dust (24 microns) extend to smaller z heights than the cool dust (450 microns). For six locations in the galaxy for which the S/N was sufficient, we present SEDs of the IR emission, including two in the halo - the first time a halo SED in an external galaxy has been presented. We have modeled these SEDs and find that the PAH fraction is similar to Galactic values (within a factor of two), with the lowest value at the galaxy's center, consistent with independent results of other galaxies. In the halo environment, the fraction of dust exposed to a colder radiation field, is of order unity, consistent with an environment in which there is no star formation. The source of excitation is likely from photons escaping from the disk.Comment: 24 pages, 17 figures, 7 tables, accepted for publication in MNRA

Ultraviolet Survey of CO and H_2 in Diffuse Molecular Clouds: The Reflection of Two Photochemistry Regimes in Abundance Relationships

(Abridged) We carried out a comprehensive far-ultraviolet (UV) survey of ^12CO and H_2 column densities along diffuse molecular Galactic sight lines in order to explore in detail the relationship between CO and H_2. We measured new CO abundances from HST spectra, new H_2 abundances from FUSE data, and new CH, CH^+, and CN abundances from the McDonald and European Southern Observatories. A plot of log N(CO) versus log N(H_2) shows that two power-law relationships are needed for a good fit of the entire sample, with a break located at log N(CO, cm^-2) = 14.1 and log N(H_2) = 20.4, corresponding to a change in production route for CO in higher-density gas. Similar logarithmic plots among all five diatomic molecules allow us to probe their relationships, revealing additional examples of dual slopes in the cases of CO versus CH (break at log N = 14.1, 13.0), CH^+ versus H_2 (13.1, 20.3), and CH^+ versus CO (13.2, 14.1). These breaks are all in excellent agreement with each other, confirming the break in the CO versus H_2 relationship, as well as the one-to-one correspondence between CH and H_2 abundances. Our new sight lines were selected according to detectable amounts of CO in their spectra and they provide information on both lower-density (< 100 cm^-3) and higher-density diffuse clouds. The CO versus H_2 correlation and its intrinsic width are shown to be empirically related to the changing total gas density among the sight lines of the sample. We employ both analytical and numerical chemical schemes in order to derive details of the molecular environments. In the low-density gas, where equilibrium-chemistry studies have failed to reproduce the abundance of CH^+, our numerical analysis shows that nonequilibrium chemistry must be employed for correctly predicting the abundances of both CH^+ and CO.Comment: 40 pages in emulateapj style, to appear in the Astrophysical Journa

Current assessment of the Red Rectangle band problem

In this paper we discuss our insights into several key problems in the identification of the Red Rectangle Bands (RRBs). We have combined three independent sets of observations in order to try to define the constraints guiding the bands. We provide a summary of the general behavior of the bands and review the evidence for a molecular origin of the bands. The extent, composition, and possible absorption effects of the bands are discussed. Comparison spectra of the strongest band obtained at three different spectral resolutions suggests that an intrinsic line width of individual rotational lines can be deduced. Spectroscopic models of several relatively simple molecules were examined in order to investigate where the current data are weak. Suggestions are made for future studies to enhance our understanding of these enigmatic bands

Oxydation des hydrocarbures satures par le systeme de Gif

SIGLECNRS T Bordereau / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

Boundary conditions for the lattice Boltzmann method : Mass conserving boundary conditions for moving walls

Based on the no-slip boundary condition for walls at rest for the lattice Boltzmann Bathnagar-Gross-Krook method by J.C.G. Verschaeve [Phys. Rev. 80,036703 (2009)], a no-slip boundary condition for walls with a tangential movement is derived. Numerical tests verify that the present boundary condition is second order accurate and stable for relaxation frequencies close to two