99 research outputs found

    A high accuracy Leray-deconvolution model of turbulence and its limiting behavior

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    In 1934 J. Leray proposed a regularization of the Navier-Stokes equations whose limits were weak solutions of the NSE. Recently, a modification of the Leray model, called the Leray-alpha model, has atracted study for turbulent flow simulation. One common drawback of Leray type regularizations is their low accuracy. Increasing the accuracy of a simulation based on a Leray regularization requires cutting the averaging radius, i.e., remeshing and resolving on finer meshes. This report analyzes a family of Leray type models of arbitrarily high orders of accuracy for fixed averaging radius. We establish the basic theory of the entire family including limiting behavior as the averaging radius decreases to zero, (a simple extension of results known for the Leray model). We also give a more technically interesting result on the limit as the order of the models increases with fixed averaging radius. Because of this property, increasing accuracy of the model is potentially cheaper than decreasing the averaging radius (or meshwidth) and high order models are doubly interesting

    Towards the Digital Institution

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    Digital Institution.We are living at a unique point in history in which all memory institutions are being transformed from purely physical institutions towards the digital institution. This transformation could not occur in previous generations, since the technologies were not in place to support this change. This transformation should also be largely completed by the next generation in 20 years or so, with all institutions will have a digital structure which reflects and complements their physical structure. It is thus our generation’s responsibility, and perhaps ours alone in the long history of memory recording, to ensure that this transformation occurs properly, so that it benefits all future generations. 9 This transformation is a one-off event and it encompasses the entire institutional operation and is not confined merely to the capturing digital images and the creation of repositories. Rather, this transformation requires a total re-engineering of the institution, and requires a rapid catch-up in knowledge, capacity and technology within a sector which is largely populated with older specialists within insufficient knowledge of the digital world. This paper presents some key elements of this transformation with which we are currently engaged to help various institutions through this sea change. Our experience has been that few institutions have started to make significant moves into this digital transformation, although everyone has accepted its necessity, and we are now at the start of the real work which is needed throughout the entire sector. This has led me to identify three major areas of work to be done

    Web-based diagnosis of misconceptions in rational numbers

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    A thesis submitted to the Wits School of Education, Faculty of Humanities, University of the Witwatersrand in fulfilment of the requirements for the degree of Doctor of Philosophy. Johannesburg, 2016.This study explores the potential for Web-based diagnostic assessments in the classroom, with specific focus on certain common challenges experienced by learners in the development of their rational number knowledge. Two schools were used in this study, both having adequate facilities for this study, comprising a well-equipped computer room with one-computer-per-learner and a fast, reliable broadband connection. Prior research on misconceptions in the rational numbers has been surveyed to identify a small set of problem types with proven effectiveness in eliciting evidence of misconceptions in learners. In addition to the problem types found from prior studies, other problem types have been included to examine how the approach can be extended. For each problem type a small item bank was created and these items were presented to the learners in test batteries of between four and ten questions. A multiple-choice format was used, with distractor choices included to elicit misconceptions, including those previously reported in prior research. The test batteries were presented in dedicated lessons to learners over four consecutive weeks to Grade 7 (school one) and Grade 8 (school two) classes from the participating schools. A number of test batteries were presented in each weekly session and, following the learners’ completion of each battery, feedback was provided to the learner with notes to help them reflect on their performance. The focus of this study has been on diagnosis alone, rather than remediation, with the intention of building a base for producing valid evidence of the fine-grained thinking of learners. This evidence can serve a variety of purposes, most significantly to inform the teacher on each learners’ stage of development in the specific micro-domains. Each micro-domain is a fine-grained area of knowledge that is the basis for lesson-sized teaching and learning, and which is highly suited to diagnostic assessment. A fine-grained theory of constructivist learning is introduced for positioning learners at a development stage in each micro-domain. This theory of development stages is the foundation I have used to explore the role of diagnostic assessment as it may be used in future classroom activity. To achieve successful implementation into time-constrained mathematics classrooms requires that diagnostic assessments are conducted as effectively and efficiently as possible. To meet this requirement, the following elements of diagnostic assessments were investigated: (1) Why are some questions better than others for diagnostic purposes? (2) How many questions need to be asked to produce valid conclusions? (3) To what extent is learner self-knowledge of item difficulty useful to identify learner thinking? A Rasch modeling approach was used for analyzing the data, and this was applied in a novel way by measuring the construct of the learners’ propensity to select a distractor for a misconception, as distinct from the common application of Rasch to measure learner ability. To accommodate multiple possible misconceptions used by a learner, parallel Rasch analyses were performed to determine the likely causes of learner mistakes. These analyses were used to then identify which questions appeared to be better for diagnosis. The results produced clear evidence that some questions are far better diagnostic discriminators than others for specific misconceptions, but failed to identify the detailed rules which govern this behavior, with the conclusion that to determine these would require a far larger research population. The results also determined that the number of such good diagnostic questions needed is often surprisingly low, and in some cases a single question and response is sufficient to infer learner thinking. The results show promise for a future in which Web-based diagnostic assessments are a daily part of classroom practice. However, there appears to be no additional benefit in gathering subjective self-knowledge from the learners, over using the objective test item results alone. Keywords: diagnostic assessment; rational numbers; common fractions; decimal numbers; decimal fractions; misconceptions; Rasch models; World-Wide Web; Web-based assessment; computer-based assessments; formative assessment; development stages; learning trajectories

    Critical success factors for an African digital library

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    Presentation at the South African Digitisation Initiative (SADI) workshop, 3 December 2014

    国立大学における「アドミッション・オフィサー」―教員主体の人員構成とその課題―

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    In this paper, we look back at the history of the birth of the profession called the “Admission Officers” belonging to the admission center of the national university. How many “Admission Officers” exist in national universities in Japan, and their personnel composition is we will clarify what is going on. In addition, we would like to consider the current status, issues, and future of "Admission Officers" in which faculty members are mainly in Japan

    A cross-institutional analysis of the effects of broadening trainee professional development on research productivity

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    © The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Brandt, P. D., Sturzenegger Varvayanis, S., Baas, T., Bolgioni, A. F., Alder, J., Petrie, K. A., Dominguez, I., Brown, A. M., Stayart, C. A., Singh, H., Van Wart, A., Chow, C. S., Mathur, A., Schreiber, B. M., Fruman, D. A., Bowden, B., Wiesen, C. A., Golightly, Y. M., Holmquist, C. E., Arneman, D., Hall, J. D., Hyman, L. E., Gould, K. L., Chalkley, R., Brennwald, P. J., Layton, R. L. A cross-institutional analysis of the effects of broadening trainee professional development on research productivity. Plos Biology, 19(7), (2021): e3000956, https://doi.org/10.1371/journal.pbio.3000956.PhD-trained scientists are essential contributors to the workforce in diverse employment sectors that include academia, industry, government, and nonprofit organizations. Hence, best practices for training the future biomedical workforce are of national concern. Complementing coursework and laboratory research training, many institutions now offer professional training that enables career exploration and develops a broad set of skills critical to various career paths. The National Institutes of Health (NIH) funded academic institutions to design innovative programming to enable this professional development through a mechanism known as Broadening Experiences in Scientific Training (BEST). Programming at the NIH BEST awardee institutions included career panels, skill-building workshops, job search workshops, site visits, and internships. Because doctoral training is lengthy and requires focused attention on dissertation research, an initial concern was that students participating in additional complementary training activities might exhibit an increased time to degree or diminished research productivity. Metrics were analyzed from 10 NIH BEST awardee institutions to address this concern, using time to degree and publication records as measures of efficiency and productivity. Comparing doctoral students who participated to those who did not, results revealed that across these diverse academic institutions, there were no differences in time to degree or manuscript output. Our findings support the policy that doctoral students should participate in career and professional development opportunities that are intended to prepare them for a variety of diverse and important careers in the workforce.Funding sources included the Common Fund NIH Director’s Biomedical Research Workforce Innovation Broadening Experiences in Scientific Training (BEST) Award. The following institutional NIH BEST awards (alphabetical by institution) included: DP7OD020322 (Boston University; AFB, ID, BMS, LEH); DP7OD020316 (University of Chicago; CAS); DP7OD018425 (Cornell University; SSV); DP7OD018428 (Virginia Polytechnic Institute; AVW, BB); DP7OD020314 (Rutgers University; JA); DP7OD020315 (University of Rochester; TB); DP7OD018423 (Vanderbilt University; KAP, AMB, KLG, RC); DP7OD020321 (University of California, Irvine; HS, DAF); DP7OD020317 (University of North Carolina, Chapel Hill; PDB, PJB, RLL); DP7 OD018427 (Wayne State University; CSC, AM). National Institutes of Health (NIH) General Medical Sciences - Science of Science Policy Approach to Analyzing and Innovating the Biomedical Research Enterprise (SCISIPBIO) Award (GM-19-011) - 1R01GM140282-01 (University of North Carolina at Chapel Hill; RLL, PDB, PJB)

    Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data.

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    Telomere length is a risk factor in disease and the dynamics of telomere length are crucial to our understanding of cell replication and vitality. The proliferation of whole genome sequencing represents an unprecedented opportunity to glean new insights into telomere biology on a previously unimaginable scale. To this end, a number of approaches for estimating telomere length from whole-genome sequencing data have been proposed. Here we present Telomerecat, a novel approach to the estimation of telomere length. Previous methods have been dependent on the number of telomeres present in a cell being known, which may be problematic when analysing aneuploid cancer data and non-human samples. Telomerecat is designed to be agnostic to the number of telomeres present, making it suited for the purpose of estimating telomere length in cancer studies. Telomerecat also accounts for interstitial telomeric reads and presents a novel approach to dealing with sequencing errors. We show that Telomerecat performs well at telomere length estimation when compared to leading experimental and computational methods. Furthermore, we show that it detects expected patterns in longitudinal data, repeated measurements, and cross-species comparisons. We also apply the method to a cancer cell data, uncovering an interesting relationship with the underlying telomerase genotype
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