282 research outputs found

    AprÚs les fiançailles, le mariage

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    AprĂšs quarante annĂ©es de vie sĂ©parĂ©e, et trois annĂ©es de prĂ©paration, la fusion des groupes Paris et Île-de-France de l\u27ABF se concrĂ©tise. HĂ©ritage de l\u27Ă©poque oĂč l\u27ABF Ă©tait structurĂ©e en sections, cette division avait perdu de son sens. Une nouvelle vie commence

    A Rosetta Stone for nature’s benefits to people

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    After a long incubation period, the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) is now underway. Underpinning all its activities is the IPBES Conceptual Framework (CF), a simplified model of the interactions between nature and people. Drawing on the legacy of previous large-scale environmental assessments, the CF goes further in explicitly embracing different disciplines and knowledge systems (including indigenous and local knowledge) in the co-construction of assessments of the state of the world's biodiversity and the benefits it provides to humans. The CF can be thought of as a kind of "Rosetta Stone" that highlights commonalities between diverse value sets and seeks to facilitate crossdisciplinary and crosscultural understanding. We argue that the CF will contribute to the increasing trend towards interdisciplinarity in understanding and managing the environment. Rather than displacing disciplinary science, however, we believe that the CF will provide new contexts of discovery and policy applications for it131sem informaçã

    Characterization of a new mouse model for human apolipoprotein A-I/C-III/A-IV deficiency

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    Human data raised the possibility that coronary heart disease is associated with mutations in the apolipoprotein gene cluste

    Developing ecosystem service indicators: experiences and lessons learned from sub-global assessments and other initiatives

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    People depend upon ecosystems to supply a range of services necessary for their survival and well-being. Ecosystem service indicators are critical for knowing whether or not these essential services are being maintained and used in a sustainable manner, thus enabling policy makers to identify the policies and other interventions needed to better manage them. As a result, ecosystem service indicators are of increasing interest and importance to governmental and inter-governmental processes, including amongst others the Convention on Biological Diversity (CBD) and the Aichi Targets contained within its strategic plan for 2011-2020, as well as the emerging Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES). Despite this growing demand, assessing ecosystem service status and trends and developing robust indicators is o!en hindered by a lack of information and data, resulting in few available indicators. In response, the United Nations Environment Programme World Conservation Monitoring Centre (UNEP-WCMC), together with a wide range of international partners and supported by the Swedish International Biodiversity Programme (SwedBio)*, undertook a project to take stock of the key lessons that have been learnt in developing and using ecosystem service indicators in a range of assessment contexts. The project examined the methodologies, metrics and data sources employed in delivering ecosystem service indicators, so as to inform future indicator development. This report presents the principal results of this project

    Biodiversity and ecosystem services science for a sustainable planet: the DIVERSITAS vision for 2012–20

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    DIVERSITAS, the international programme on biodiversity science, is releasing a strategic vision presenting scientific challenges for the next decade of research on biodiversity and ecosystem services: “Biodiversity and Ecosystem Services Science for a Sustainable Planet”. This new vision is a response of the biodiversity and ecosystem services scientific community to the accelerating loss of the components of biodiversity, as well as to changes in the biodiversity science-policy landscape (establishment of a Biodiversity Observing Network — GEO BON, of an Intergovernmental science-policy Platform on Biodiversity and Ecosystem Services — IPBES, of the new Future Earth initiative; and release of the Strategic Plan for Biodiversity 2011–2020). This article presents the vision and its core scientific challenges.Fil: Larigauderie, Anne. DIVERSITAS. MusĂ©um National d’Histoire Naturelle; FranciaFil: Prieur Richard, Anne Helene. DIVERSITAS. MusĂ©um National d’Histoire Naturelle; FranciaFil: Mace, Georgina. Imperial College London. Center for Population Biology; Reino UnidoFil: Londsdale, Mark. CSIRO Ecosystem Sciences; AustraliaFil: Mooney, Harold A.. Stanford University. Department of Biological Sciences; Estados UnidosFil: Brussaard, Lijbert. Wageningen University, Soil Quality Department; PaĂ­ses BajosFil: Cooper, David. Secretariat of the Convention on Biological Diversity; CanadĂĄFil: Wolfgang, Cramer. Institut MĂ©diterranĂ©en de BiodiversitĂ© et d’Ecologie marine et continentale; FranciaFil: Daszak, Peter. EcoHealth Alliance. Wildlife Trust; Estados UnidosFil: Diaz, Sandra Myrna. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Centro CientĂ­fico TecnolĂłgico Conicet - CĂłrdoba. Instituto Multidisciplinario de BiologĂ­a Vegetal. Universidad Nacional de CĂłrdoba. Facultad de Ciencias Exactas FĂ­sicas y Naturales. Instituto Multidisciplinario de BiologĂ­a Vegetal; ArgentinaFil: Duraiappah, Anantha. International Human Dimensions Programme; AlemaniaFil: Elmqvist, Thomas. University of Stockholm. Department of Systems Ecology and Stockholm Resilience Center; SueciaFil: Faith, Daniel. The Australian Museum; AustraliaFil: Jackson, Louise. University of California; Estados UnidosFil: Krug, Cornelia. DIVERSITAS. MusĂ©um National d’Histoire Naturelle; FranciaFil: Leadley, Paul. UniversitĂ© Paris. Laboratoire Ecologie SystĂ©matique Evolution, Ecologie des Populations et CommunautĂ©s; FranciaFil: Le Prestre, Philippe. Laval University; CanadĂĄFil: Matsuda, Hiroyuki. Yokohama National University; JapĂłnFil: Palmer, Margaret. University of Maryland; Estados UnidosFil: Perrings, Charles. Arizona State University; Estados UnidosFil: Pulleman, Mirjam. Wageningen University; PaĂ­ses BajosFil: Reyers, Belinda. Natural Resources and Environment; SudĂĄfricaFil: Rosa, Eugene A.. Washington State University; Estados UnidosFil: Scholes, Robert J.. Natural Resources and Environment; SudĂĄfricaFil: Spehn, Eva. Universidad de Basilea; SuizaFil: Turner II, B. L.. Arizona State University; Estados UnidosFil: Yahara, Tetsukazu. Kyushu University; JapĂł

    Perilipin 2 (PLIN2)-Deficiency Does Not Increase Cholesterol-Induced Toxicity in Macrophages

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    Interventions on macrophages/foam cells to redirect intracellular cholesterol towards efflux pathways could become a very valuable addition to our therapeutic arsenal against atherosclerosis. However, certain manipulations of the cholesteryl ester cycle, such as the inhibition of ACAT1, an ER-resident enzyme that re-esterifies cholesterol, are not well tolerated. Previously we showed that targeting perilipin-2 (PLIN2), a major lipid droplet (LD)-associated protein in macrophages, prevents foam cell formation and protects against atherosclerosis. Here we have assessed the tolerance of PLIN2-deficient bone marrow derived macrophages (BMM) to several lipid loading conditions similar to the found during atherosclerosis development, including exposure to modified low-density lipoprotein (mLDL) and 7-ketocholesterol (7-KC), a free cholesterol (FC) metabolite, in media with or without cholesterol acceptors. BMM isolated from mice that do or do not express PLIN2 were tested for apoptosis (TUNEL and cleaved caspase-3), ER stress (CHOP induction and XBP-1 splicing), and inflammation (TNF-α and IL-6 mRNA levels). Like in other cell types, PLIN2 deficiency impairs LD buildup in BMM. However, while most stress parameters were elevated in macrophages under ACAT inhibition and 7-KC loading, PLIN2 inactivation was well tolerated. The data support the safety of targeting PLIN2 to prevent foam cell formation and atherosclerosis

    Membership nominations in international scientific assessments

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    International scientific assessments are transnational knowledge-based expert networks with a mandate to advise policymakers. A well-known example is the Millennium Ecosystem Assessment (MA), which synthesized research on ecosystem services between 2001 and 2005, utilizing the knowledge of 1,360 expert members. Little, however, is known about the membership composition and the driving forces behind membership nominations in the MA and similar organizations. Here we introduce a survey data set on recruitment in the MA and analyse nomination patterns among experts as a complex network. The results indicate that membership recruitment was governed by prior contacts in other transnational elite organizations and a range of other factors related to personal affinity. Network analysis demonstrates how some core individuals were particularly influential in shaping the overall membership composition of the group. These findings add to recently noted concerns about the lack of diversity of views represented in international scientific assessments

    Identification of female sex pheromone for monitoring the barred tooth striped moth, trichopteryx polycommata, a priority conservation species

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    Pheromone-baited traps can be excellent tools for sensitive detection of insects of conservation concern. Here, identification of the sex pheromone of Trichopteryx polycommata (Denis & SchiffermĂŒller, 1775), an under-recorded UK priority species, is reported. In analyses of extracts of the pheromone glands of female T. polycommata by gas chromatography coupled to electroantennographic recording from the antenna of a male moth, a single active component was detected. This was identified as (Z,Z)-6,9-nonadecadiene (Z,Z6,9-19:H) by comparison of its mass spectrum and retention times with those of the synthetic standard. In a pilot field trial in Kent, UK, T. polycommata males were caught in pheromone traps baited with lures loaded with 1 mg and 2 mg (Z,Z)-6,9-19:H. Optimum lure loading was identified in a further five trials in Kent, Sussex and Lancashire where lures of 0, 0.001, 0.01, 0.1, 1, 2, 5 and 10 mg loadings were tested. Traps baited with 1 to 10 mg of ZZ6,9-19:H caught significantly more T. polycommata than traps baited with 0 mg and 0.001 mg. In a pilot survey of T. polycommata using pheromone lures around Morecambe Bay, UK, T. polycommata males were captured at 122 new sites within the three counties where trials took place, demonstrating the potential of pheromone monitoring to increase knowledge of abundance, distribution and ecology of this elusive species
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