435 research outputs found

    Exploring the Associations of Cultural Intelligence with Culturally Responsive Teaching Self Efficacy, Relevant Experiences, and Job Satisfaction in a sample of White American Teachers

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    The idea of being “culturally intelligent” has become an established concept in the corporate world and now, more recently, moved into the realm of education. The most relevant questions for educators remain: How do some White educators become more culturally intelligent than others? Does cultural intelligence relate to effective teaching practices? The purpose of the study was to examine whether job satisfaction, culturally responsive teaching self-efficacy and relevant experiences (e.g., having studied abroad) related to cultural intelligence (CQ) in White teachers. Data was collected from practicing K-12 teachers in the U.S. who identified as White and non-Hispanic (N = 130). Results showed that all four aspects of CQ (i.e., behavioral, cognitive, metacognitive, and motivational) were positively correlated with culturally responsive teaching self-efficacy and relevant experiences. Three of the four CQ subscales (i.e., behavioral, metacognitive, and motivational) were positively correlated with teachers’ job satisfaction. In multiple regression analysis, motivational and metacognitive CQ were related to culturally responsive teaching self-efficacy, whereas motivational and cognitive CQ were significantly related to relevant experiences. In multiple regression analysis, motivational CQ was related to job satisfaction for teachers who taught in predominantly non-White schools. Multiple regression analysis indicated that CQ was not a significant predictor of job satisfaction for teachers in predominantly White schools. These results suggest that CQ may be a useful measure of cultural understanding for K-12 teachers

    Designing Web-enabled services to provide damage estimation maps caused by natural hazards

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    The availability of building stock inventory data and demographic information is an important requirement for risk assessment studies when attempting to predict and estimate losses due to natural hazards such as earthquakes, storms, floods or tsunamis. The better this information is provided, the more accurate are predictions on damage to structures and lifelines and the better can expected impacts on the population be estimated. When a disaster strikes, a map is often one of the first requirements for answering questions related to location, casualties and damage zones caused by the event. Maps of appropriate scale that represent relative and absolute damage distributions may be of great importance for rescuing lives and properties, and for providing relief. However, this type of maps is often difficult to obtain during the first hours or even days after the occurrence of a natural disaster. The Open Geospatial Consortium Web Services (OWS) Specifications enable access to datasets and services using shared, distributed and interoperable environments through web-enabled services. In this paper we propose the use of OWS in view of these advantages as a possible solution for issues related to suitable dataset acquisition for risk assessment studies. The design of web-enabled services was carried out using the municipality of Managua (Nicaragua) and the development of damage and loss estimation maps caused by earthquakes as a first case study. Four organizations located in different places are involved in this proposal and connected through web services, each one with a specific role

    A Spatial Model for the Needle Losses of Pine-Trees in the Forests of Baden-Württemberg: An Application of Bayesian Structured Additive Regression

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    Summary The data that are analysed are from a monitoring survey which was carried out in 1994 in the forests of Baden-Württemberg, a federal state in the south-western region of Germany. The survey is part of a large monitoring scheme that has been carried out since the 1980s at different spatial and temporal resolutions to observe the increase in forest damage. One indicator for tree vitality is tree defoliation, which is mainly caused by intrinsic factors, age and stand conditions, but also by biotic (e.g. insects) and abiotic stresses (e.g. industrial emissions). In the survey, needle loss of pine-trees and many potential covariates are recorded at about 580 grid points of a 4 km × 4 km grid. The aim is to identify a set of predictors for needle loss and to investigate the relationships between the needle loss and the predictors. The response variable needle loss is recorded as a percentage in 5% steps estimated by eye using binoculars and categorized into healthy trees (10% or less), intermediate trees (10–25%) and damaged trees (25% or more). We use a Bayesian cumulative threshold model with non-linear functions of continuous variables and a random effect for spatial heterogeneity. For both the non-linear functions and the spatial random effect we use Bayesian versions of P-splines as priors. Our method is novel in that it deals with several non-standard data requirements: the ordinal response variable (the categorized version of needle loss), non-linear effects of covariates, spatial heterogeneity and prediction with missing covariates. The model is a special case of models with a geoadditive or more generally structured additive predictor. Inference can be based on Markov chain Monte Carlo techniques or mixed model technology

    National and regional variations in timely adherence to recommended measles vaccination scheme in 2-years old in Switzerland, 2005–2019

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    BACKGROUND Although monitoring of vaccination program performance is usually evaluated by measurement of vaccine coverage, timely uptake is rarely part of this assessment. This study aims to examine the timeliness of the administration of a measles-containing-vaccine (MCV) for 2-year-old children between 2005 and 2019. METHODS We used data from the Swiss National Vaccination Coverage Survey 2005-2019 for the study. We defined timely vaccinated as a vaccination administered within the recommended age specified in the Swiss National Vaccination Schedule, with an added tolerance period of 30.4 days for both MCV 1 and 2 doses. The median delay time was estimated by Kaplan-Meier survival curve and examined using log-rank test. A Cox hazard ratio was used to identify factors associated with delay. RESULTS 81% (95% CI:79-82%) of toddlers were timely vaccinated for MCV1 and 82% (95% CI:81-83%) for MCV2 in survey period 2017-2019. Between 2005 and 2019, the median age of vaccinated children ranged between 12.2 and 12.5 and 18.3-22.0 months for MCV1 and MCV2 with median delay of 44 and 38 days, respectively, at the national level. Children in the French-, Italian- and German-speaking regions were vaccinated earlier between 2005 and 2019 for MCV1 (vaccination coverage range before 10 months of age: 1.7-45.9%, 1.2-35.3% and 1.4-15.0%, respectively). Nationality, linguistic regions, and survey periods were the strongest predictive factors related to prolonged delay time. CONCLUSION Overall adherence to recommendations has improved over time, as MCV coverage has significantly increased over the years with differences across linguistic regions. Vaccinations were administered earlier and with shorter delay time

    Predicting Commercial Pilot Training Performance: A Validation Study

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    Accepted manuscript version, licensed CC BY-NC-ND 4.0. The main purpose of this study was to examine the predictive validity of the system used for ab initio selection of candidates to a bachelor program in aviation. The selection includes paper-and-pencil tests, computer-based tests, and an interview. A total of 188 candidates participated in the validation study. The total test score predicted the results of three exams in aviation theory (r = .27–.38) and extra flying hours needed (−.22), but not mean university grade. The regression analyses indicated that all predictors (tests and interview ratings) explained 25% of the variance in aviation theory, 19% in extra flying hours needed, and 7% in mean university grade. The overall findings confirmed the predictive validity of selection tests, especially the computer-based tests

    Up-regulation of amino acid transporter SLC6A19 activity and surface protein abundance by PKB/Akt and PIKfyve

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    Background: The amino acid transporter B0AT1 (SLC6A19) accomplishes concentrative cellular uptake of neutral amino acids. SLC6A19 is stimulated by serum- & glucocorticoid-inducible kinase (SGK) isoforms. SGKs are related to PKB/Akt isoforms, which also stimulate several amino acid transporters. PKB/Akt modulates glucose transport in part by phosphorylating and thus activating phosphatidylinositol-3-phosphate-5-kinase (PIKfyve), which fosters carrier protein insertion into the cell membrane. The present study explored whether PKB/Akt and/or PIKfyve stimulate SLC6A19. Methods: SLC6A19 was expressed in Xenopus oocytes with or without wild-type PKB/Akt or inactive T308A/S473APKB/Akt without or with additional expression of wild-type PIKfyve or PKB/Akt-resistant S318APIKfyve. Electrogenic amino acid transport was determined by dual electrode voltage clamping. Results: In SLC6A19-expressing oocytes but not in water-injected oocytes, the addition of the neutral amino acid L-leucine (2 mM) to the bath generated a current (Ile), which was significantly increased following coexpression of PKB/Akt, but not by coexpression of T308A/S473APKB/Akt. The effect of PKB/Akt was augmented by additional coexpression of PIKfyve but not of S318APIKfyve. Coexpression of PKB/Akt enhanced the maximal transport rate without significantly modifying the affinity of the carrier. The decline of Ile following inhibition of carrier insertion by brefeldin A (5 µM) was similar in the absence and presence of PKB/Akt indicating that PKB/Akt stimulated carrier insertion into rather than inhibiting carrier retrieval from the cell membrane. Conclusion: PKB/Akt up-regulates SLC6A19 activity, which may foster amino acid uptake into PKB/Akt-expressing epithelial and tumor cells

    Regulation of CLC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases

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    Regulation of ClC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases.BackgroundClC-Ka and ClC-Kb, chloride channels participating in renal tubular Cl− transport, require the coexpression of barttin to become functional. Mutations of the barttin gene lead to the Bartter's syndrome variant BSND, characterized by congenital deafness and severe renal salt wasting. Barttin bears a proline-tyrosine motif, a target structure for the ubiquitin ligase Nedd4-2, which mediates the clearance of channel proteins from the cell membrane. Nedd4-2 is, in turn, a target of the serum- and glucocorticoid-inducible kinase SGK1, which phosphorylates and, thus, inactivates the ubiquitin ligase. ClC-Ka also possesses a SGK1 consensus site in its sequence. We hypothesized that ClC-Ka/barttin is stimulated by SGK1, and down-regulated by Nedd4-2, an effect that may be reversed by SGK1 and its isoforms, SGK2 or SGK3.MethodsTo test this hypothesis, ClC-Ka/barttin was heterologously expressed in Xenopus oocytes with or without the additional expression of Nedd4-2, SGK1, SGK2, SGK3, constitutively active S422DSGK1, or inactive K127NSGK1.ResultsExpression of ClC-Ka/barttin induced a slightly inwardly rectifying current that was significantly decreased upon coexpression of Nedd4-2, but not the catalytically inactive mutant C938SNedd4-2. The coexpression of S422DSGK1, SGK1, or SGK3, but not SGK2 or K127NSGK1 significantly stimulated the current. Moreover, S422DSGK1, SGK1, and SGK3 also phosphorylated Nedd4-2 and thereby inhibited Nedd4-2 binding to its target. The down-regulation of ClC-Ka/barttin by Nedd4-2 was abolished by elimination of the PY motif in barttin.ConclusionClC-Ka/barttin channels are regulated by SGK1 and SGK3, which may thus participate in the regulation of transport in kidney and inner ear

    Low-frequency gravitational-wave science with eLISA/NGO

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    We review the expected science performance of the New Gravitational-Wave Observatory (NGO, a.k.a. eLISA), a mission under study by the European Space Agency for launch in the early 2020s. eLISA will survey the low-frequency gravitational-wave sky (from 0.1 mHz to 1 Hz), detecting and characterizing a broad variety of systems and events throughout the Universe, including the coalescences of massive black holes brought together by galaxy mergers; the inspirals of stellar-mass black holes and compact stars into central galactic black holes; several millions of ultracompact binaries, both detached and mass transferring, in the Galaxy; and possibly unforeseen sources such as the relic gravitational-wave radiation from the early Universe. eLISA's high signal-to-noise measurements will provide new insight into the structure and history of the Universe, and they will test general relativity in its strong-field dynamical regime.Comment: 20 pages, 8 figures, proceedings of the 9th Amaldi Conference on Gravitational Waves. Final journal version. For a longer exposition of the eLISA science case, see http://arxiv.org/abs/1201.362
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