Photometric Properties of Galaxy Population in the Cluster EIS 0048-2942 at z~0.64

~Deep photometric data in the V-, R-, I-, z- and K-bands for the cluster of galaxies EIS 0048-2942 are used to investigate the properties of the galaxy populations at z~0.64 in a field of 2.5x2.5 Mpc^2. The sample of candidate cluster members (N = 171) is selected by the photometric redshift technique and is complete up to I=22.5. Galaxies were classified as spheroids and disks according to the shape of the light profile in the I-band, as parametrized by the Sersic index. In both optical and NIR, spheroids define a sharp colour-magnitude sequence, whose slope and zero points are consistent with a high formation redshift (z_f > 2). The disk population occupies a different region in the colour-magnitude diagram, having bluer colours with respect to the red sequence. Interestingly, we find some level of mixing between the properties of the two classes: some disks lie on the colour-magnitude sequence or are redder, while some spheroids turn out to be bluer. The spatial distribution of cluster galaxies show a clumpy structure, with a main over-density of radius ~0.5 Mpc, and at least two other clumps distant ~1 Mpc from the center. The various sub-structures are mostly populated by the red galaxies, while the blue population has an almost uniform distribution. The fraction of blue galaxies in EIS 0048-2942 is f_B=0.11 +/-0.07. This is much lower than what expected on the basis of the Butcher-Oemler effect at lower redshifts.Comment: 22 pages, 12 figures. A&A in pres

Segregation Effects According to the Evolutionary Stage of Galaxy Groups

We study segregation phenomena in 57 groups selected from the 2PIGG catalog of galaxy groups. The sample corresponds to those systems located in areas of at least 80% redshift coverage out to 10 times the radius of the groups. The dynamical state of the galaxy systems was determined after studying their velocity distributions. We have used the Anderson-Darling test to distinguish relaxed and non-relaxed systems. This analysis indicates that 84% of groups have galaxy velocities consistent with the normal distribution, while 16% of them have more complex underlying distributions. Properties of the member galaxies are investigated taking into account this classification. Our results indicate that galaxies in Gaussian groups are significantly more evolved than galaxies in non-relaxed systems out to distances of about 4R200, presenting signficantly redder (B-R) color. We also find evidence that galaxies with M_R < -21.5 in Gaussian groups are closer to the condition of energy equipartition.Comment: 5 pages, 4 figures, accepted for publication in the MNRAS Letter

Consideraciones penales y criminológicas sobre el delito de feminicidio en el marco de la política criminal del estado peruano, periodo 2020 – 2021

Por lo cual el objetivo de la presente investigación buscará enumerar las consideraciones penales y criminológicas sobre el delito de feminicidio que se deben tener en cuenta en el marco de la política criminal del Estado peruano, periodo 2020- 2021. En cuanto al tipo de investigación que se empleó fue de tipo aplicada, porque el tesista buscará relacionar las variables de estudio en la actualidad y realidad problemática, la investigación es de diseño no experimental con nivel descriptivo- correlacional y enfoque cuantitativo. La población de estudio está conformada por 1500 personas y como muestra 60 abogados hábiles. De los resultados que se han dado se tiene que es cierto que el delito de feminicidio vulnera el principio de mínima proporcionalidad en el marco de la política criminal

Comparison of properties of biochar produced from different types of lignocellulosic biomass by slow pyrolysis at 600 °C

Production of biochar from corn cob and corn stalk has gained great interest for efficient waste management with benefits of improving soil properties, increasing crop productivity, and contributing to carbon sequestration. This study investigated slow pyrolysis of corn cob and corn stalk at 600 °C to characterize yields and properties of products, with focus on solid biochar. Spruce wood, a rather well studied woody biomass, was also included for comparison purposes. It was observed that yields of biochar and condensates from corn cob, corn stalk, and spruce wood were comparable. However, gas release profiles and yields from the three biomasses were quite different, which is mainly related to the different chemical compositions (i.e., hemicellulose, cellulose, lignin, and inorganic species) of the studied raw feedstocks. The produced biochars were analyzed for proximate analysis, CHNS-elemental analysis, specific surface area and specific pore volume for pores in the nm-range, inorganic composition, solid functional groups, and aromaticity. The corn cob and corn stalk biochar presented significantly higher concentration of inorganic elements, especially P and K, favoring soil application. The SEM analysis results showed that the spruce wood biochar has different microstructure than corn cob and corn stalk biochars. Condensates and light gases, as by-products from biochar production, contained over 50% of the energy and 40% of the total carbon of the initial biomass. Utilization of the condensates and light gases as valuable resources is therefore critical for improving environmental and energy benefits of the biochar production process.Comparison of properties of biochar produced from different types of lignocellulosic biomass by slow pyrolysis at 600 °CpublishedVersio

CARINA synthesis project: pH data scale unification and cruise adjustments

Data on carbon and carbon-relevant hydrographic and hydrochemical parameters from 188 previously non-publicly available cruise data sets in the Artic Mediterranean Seas (AMS), Atlantic Ocean and Southern Ocean have been retrieved and merged to a new database: CARINA (CARbon IN the Atlantic Ocean). These data have gone through rigorous quality control (QC) procedures to assure the highest possible quality and consistency. The data for most of the measured parameters in the CARINA database were objectively examined in order to quantify systematic differences in the reported values. Systematic biases found in the data have been corrected in the data products, three merged data files with measured, calculated and interpolated data for each of the three CARINA regions; AMS, Atlantic Ocean and Southern Ocean. Out of a total of 188 cruise entries in the CARINA database, 59 reported pH measured values. All reported pH data have been unified to the Sea-Water Scale (SWS) at 25 C. Here we present details of the secondary QC of pH in the CARINA database and the scale unification to SWS at 25 C. The pH scale has been converted for 36 cruises. Procedures of quality control, including crossover analysis between cruises and inversion analysis are described. Adjustments were applied to the pH values for 21 of the cruises in the CARINA dataset. With these adjustments the CARINA database is consistent both internally as well as with the GLODAP data, an oceanographic data set based on the World Hydrographic Program in the 1990s. Based on our analysis we estimate the internal consistency of the CARINA pH data to be 0.005 pH units. The CARINA data are now suitable for accurate assessments of, for example, oceanic carbon inventories and uptake rates, for ocean acidification assessment and for model validation

Using Social Media for Actionable Disease Surveillance and Outbreak Management: A Systematic Literature Review

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IMEP-23: The Eight WFD PAHs in Water in Presence of Humic Acid

IMEP-23 is linked to the Water Framework Directive (WFD). It studied the capability of control laboratories to measure the eight WFD PAHs in the presence of humic acid in a water matrix. Humic acid simulates natural colloidal organic matter and is known to adsorb PAHs. This gives rise to various issues that are of large importance for the control laboratories. Participants' results were benchmarked against the IMEP certified reference values. On average 80 % of the z scores was satisfactory. Zeta scores were calculated for those laboratories who provided an uncertainty estimate. These were less satisfactory and this shows that many laboratories encounter difficulties to provide a reasonable uncertainty estimate.JRC.D.4-Isotope measurement

Transcriptome Remodeling Contributes to Epidemic Disease Caused by the Human Pathogen Streptococcus pyogenes

UNLABELLED For over a century, a fundamental objective in infection biology research has been to understand the molecular processes contributing to the origin and perpetuation of epidemics. Divergent hypotheses have emerged concerning the extent to which environmental events or pathogen evolution dominates in these processes. Remarkably few studies bear on this important issue. Based on population pathogenomic analysis of 1,200 Streptococcus pyogenes type emm89 infection isolates, we report that a series of horizontal gene transfer events produced a new pathogenic genotype with increased ability to cause infection, leading to an epidemic wave of disease on at least two continents. In the aggregate, these and other genetic changes substantially remodeled the transcriptomes of the evolved progeny, causing extensive differential expression of virulence genes and altered pathogen-host interaction, including enhanced immune evasion. Our findings delineate the precise molecular genetic changes that occurred and enhance our understanding of the evolutionary processes that contribute to the emergence and persistence of epidemically successful pathogen clones. The data have significant implications for understanding bacterial epidemics and for translational research efforts to blunt their detrimental effects. IMPORTANCE The confluence of studies of molecular events underlying pathogen strain emergence, evolutionary genetic processes mediating altered virulence, and epidemics is in its infancy. Although understanding these events is necessary to develop new or improved strategies to protect health, surprisingly few studies have addressed this issue, in particular, at the comprehensive population genomic level. Herein we establish that substantial remodeling of the transcriptome of the human-specific pathogen Streptococcus pyogenes by horizontal gene flow and other evolutionary genetic changes is a central factor in precipitating and perpetuating epidemic disease. The data unambiguously show that the key outcome of these molecular events is evolution of a new, more virulent pathogenic genotype. Our findings provide new understanding of epidemic disease

Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression

Cholangiocarcinoma (CCA) has a poor prognosis due to widespread intrahepatic spread. Aspartate β-hydroxylase (ASPH) is a transmembrane protein and catalyzes the hydroxylation of aspartyl and asparaginyl residues in calcium binding epidermal growth factor (cbEGF)-like domains of various proteins, including Notch receptors and ligands. ASPH is highly overexpressed (\u3e95%) in human CCA tumors. We explored the molecular mechanisms by which ASPH mediated the CCA malignant phenotype and evaluated the potential of ASPH as a therapeutic target for CCA. The importance of expression and enzymatic activity of ASPH for CCA growth and progression was examined using shRNA “knockdown” and a mutant construct that reduced its catalytic activity. Second generation small molecule inhibitors (SMIs) of β-hydroxylase activity were developed and used to target ASPH in vitro and in vivo. Subcutaneous and intrahepatic xenograft rodent models were employed to determine anti-tumor effects on CCA growth and development. It was found that the enzymatic activity of ASPH was critical for mediating CCA progression, as well as inhibiting apoptosis. Mechanistically, ASPH overexpression promoted Notch activation and modulated CCA progression through a Notch1-dependent cyclin D1 pathway. Targeting ASPH with shRNAs or a SMI significantly suppressed CCA growth in vivo