Classification of newborn EEG maturity with Bayesian averaging over decision trees

EEG experts can assess a newborn’s brain maturity by visual analysis of age-related patterns in sleep EEG. It is highly desirable to make the results of assessment most accurate and reliable. However, the expert analysis is limited in capability to provide the estimate of uncertainty in assessments. Bayesian inference has been shown providing the most accurate estimates of uncertainty by using Markov Chain Monte Carlo (MCMC) integration over the posterior distribution. The use of MCMC enables to approximate the desired distribution by sampling the areas of interests in which the density of distribution is high. In practice, the posterior distribution can be multimodal, and so that the existing MCMC techniques cannot provide the proportional sampling from the areas of interest. The lack of prior information makes MCMC integration more difficult when a model parameter space is large and cannot be explored in detail within a reasonable time. In particular, the lack of information about EEG feature importance can affect the results of Bayesian assessment of EEG maturity. In this paper we explore how the posterior information about EEG feature importance can be used to reduce a negative influence of disproportional sampling on the results of Bayesian assessment. We found that the MCMC integration tends to oversample the areas in which a model parameter space includes one or more features, the importance of which counted in terms of their posterior use is low. Using this finding, we proposed to cure the results of MCMC integration and then described the results of testing the proposed method on a set of sleep EEG recordings

Low speed aerodynamic characteristics of an 0.075-scale F-15 airplane model at high angles of attack and sideslip

An 0.075 scale model representative of the F-15 airplane was tested in the Ames 12 foot pressure wind tunnel at a Mach number of 0.16 to determine static longitudinal and lateral directional characteristics at spin attitudes for Reynolds numbers from 1.48 to 16.4 million per meter (0.45 to 5.0 million per foot). Angles of attack ranged from 0 to +90 deg and from -40 deg to -80 deg while angles of sideslip were varied from -20 deg to +30 deg. Data were obtained for nacelle inlet ramp angles of 0 to 11 deg with the left and right stabilators deflected 0, -25 deg, and differentially 5 deg and -5 deg. The normal pointed nose and two alternate nose shapes were also tested along with several configurations of external stores. Analysis of the results indicate that at higher Reynolds numbers there is a slightly greater tendency to spin inverted than at lower Reynolds numbers. Use of a hemispherical nose in place of the normal pointed nose provided an over correction in simulating yawing moment effects at high Reynolds numbers

Prayer and subjective well-being: An examination of six different types of prayer

Participants (N = 430) were recruited online and completed a measure of six prayer types (adoration, confession, thanksgiving, supplication, reception, and obligatory prayer). Measures of subjective well-being (self-esteem, optimism, meaning in life, satisfaction with life) were also administered. Three forms of prayer (adoration, thanksgiving, reception) had consistently positive relations with well-being measures, whereas the other three forms of prayer had negative or null relations with the well-being measures. The prayer types having positive effects appear to be less ego-focused, and more focused on God, whereas the negative types have an opposite nature. These results highlight the role of psychological meaning as a part of the process whereby prayer impacts psychological well-being

Prayer and subjective well-being: An examination of six different types of prayer

Participants (N = 430) were recruited online and completed a measure of six prayer types (adoration, confession, thanksgiving, supplication, reception, and obligatory prayer). Measures of subjective well-being (self-esteem, optimism, meaning in life, satisfaction with life) were also administered. Three forms of prayer (adoration, thanksgiving, reception) had consistently positive relations with well-being measures, whereas the other three forms of prayer had negative or null relations with the well-being measures. The prayer types having positive effects appear to be less ego-focused, and more focused on God, whereas the negative types have an opposite nature. These results highlight the role of psychological meaning as a part of the process whereby prayer impacts psychological well-being

Prayer and subjective well-being: An examination of six different types of prayer

Participants (N = 430) were recruited online and completed a measure of six prayer types (adoration, confession, thanksgiving, supplication, reception, and obligatory prayer). Measures of subjective well-being (self-esteem, optimism, meaning in life, satisfaction with life) were also administered. Three forms of prayer (adoration, thanksgiving, reception) had consistently positive relations with well-being measures, whereas the other three forms of prayer had negative or null relations with the well-being measures. The prayer types having positive effects appear to be less ego-focused, and more focused on God, whereas the negative types have an opposite nature. These results highlight the role of psychological meaning as a part of the process whereby prayer impacts psychological well-being

Spin-Tunnel Investigation of a 1/20-Scale Model of the Northrop F-5E Airplane

An investigation has been conducted in the Langley spin tunnel to determine the spin and recovery characteristics of a 1/20-scale model of the Northrop F-5E airplane. The investigation included erect and inverted spins, a range of center-of- gravity locations and moments of inertia, symmetric and asymmetric store loadings, and a determination of the parachute size required for emergency spin recovery. The effects of increased elevator trailing-edge-up deflections, of leading-edge and trailing-edge flap deflections, and of simulating the geometry of large external stores were also determined

B_K from quenched overlap QCD

We present an exploratory calculation of the standard model Delta S=2 matrix element relevant for indirect CP violation in K -> pi pi decays. The computation is performed with overlap fermions in the quenched approximation at beta=6.0 on a 16^3x32 lattice. The resulting bare matrix element is renormalized non-perturbatively. Our preliminary result is B_K^{NDR}(2 GeV)=0.61(7), where the error does not yet include an estimate of systematic uncertainties.Comment: 3 pages, 2 figures, Lattice2002(matrixel). Parallel session talk by L. Lellouch at the 20th International Symposium on Lattice Field Theory (Lattice 2002), Boston, Massachusetts, 24-29 June 200

Long-Tailed Trapping Times and Levy Flights in a Self-Organized Critical Granular System

We present a continuous time random walk model for the scale-invariant transport found in a self-organized critical rice pile [Christensen et al., Phys. Rev. Lett. 77, 107 (1996)]. From our analytical results it is shown that the dynamics of the experiment can be explained in terms of L\'evy flights for the grains and a long-tailed distribution of trapping times. Scaling relations for the exponents of these distributions are obtained. The predicted microscopic behavior is confirmed by means of a cellular automaton model.Comment: 4 pages, RevTex, includes 3 PostScript figures, submitted to Phys. Rev. Let

Combined Hepatocellular Carcinoma and Neuroendocrine Carcinoma Presenting with Hypercalcemia

Background: Malignancy-associated hypercalcemia (MAHC) occurs in 20-30% of cancer patients and is a common cause of hypercalcemia among hospitalized patients. Its pathophysiology is generally based on bone metastases or the production of parathyroid hormone-related peptide (PTHrP) by tumor cells. The secreted PTHrP causes hypercalcemia via increased calcium absorption at the kidney and increased bone resorption. Here, we present a rare case of combined hepatocellular carcinoma (HCC) and neuroendocrine carcinoma (NEC) presenting with hypercalcemia. Case History: A 67-year-old male with a past medical history of alcohol abuse and previously treated Hepatitis C infection in 2012 with ledipasvir/sobosbuvir, was referred to our hospital for evaluation of hypercalcemia. Patient was in his usual state of health until 3 weeks ago when he started having fatigue, nausea, and anorexia. This was also associated with impaired memory and confusion. He was seen at an outside hospital and was found to have a calcium of 16.1 mg/dL (normal range 8.5-10.2 mg/dL), so he was given IV fluids, zoledronic acid and calcitonin with improvement in calcium to 10.8 mg/dL. Computerized tomography (CT) scan of chest/abdomen/pelvis showed a cirrhotic liver and a 6.5 cm hypodense mass within the left hepatic lobe. CT thoracolumbar spine was negative for lytic or blastic lesions with no acute fracture or dislocation. Patient was stabilized and transferred to our hospital for escalation of care. His parathyroid hormone (PTH) was low at 8 pg/ml (15-65 pg/ml) and PTHrP was high at 105 pg/ml (14-27 pg/ml). Repeat imaging with MRI showed a 17 x 8 cm area of signal abnormality with 2 more focal anomalies within, suspicious for malignancy which may be infiltrative. MRI thoracolumbar was negative for any metastasis, fractures or lytic lesions. Skeletal series was also negative for lytic lesions. Microscopic evaluation of the CT-guided liver biopsy showed two distinct patterns. A typical moderately differentiated HCC and a second malignant focus composed of hyperchromatic small to intermediate sized cells with apoptosis, atypical mitoses, vaguely palisading tumor cells around foci of necrosis. This second focus stained positively with CD56 and CAM 5.2 was suggestive of neuroendocrine differentiation and epithelial lineage. Background hepatic parenchyma showed early cirrhosis likely secondary to long standing hepatitis C or due to alcohol abuse. Tumor markers including alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA 19-9) were all negative. His workup was negative for another primary malignancy. His disease course was complicated by altered mental status and Klebsiella pneumoniae bacteremia. His PTHrP increased to 335 pg/ml. He received supportive care and expired 3 weeks from initial presentation. Conclusion: Primary HCC and NEC generally tend to have a poorer prognosis than conventional HCC. To our knowledge, this case is the second report of primary mixed HCC and NEC associated with MAHC caused by the production of PTHrP.https://scholarlycommons.henryford.com/merf2020caserpt/1054/thumbnail.jp