Composition chimique, dégradabilité in sacco et produits de fermentation in vitro de la fétuque élevée (Festuca arundinacea

Objectifs : En vue d’une sélection pour une utilisation comme aliment pour bétail, vingt quatre écotypes de fétuque élevée (Festuca arundinacea) provenant du milieu naturel du nord de la Belgique ont été étudiés afin d’en déterminer la valeur nutritionnelle.Méthodologie et Résultats : La composition chimique, la dégradabilité in sacco et les incubations in vitro ont été réalisés. Un mouton adulte fistulé au niveau du rumen a été utilisé pour la détermination de la dégradabilité in sacco des écotypes et les incubations in vitro. La teneur moyenne en MAT (8,0% MS) des 24 écotypes étudiés est faible. Les écotypes de Festuca arundinacea présentent en moyenne une meilleure dégradabilité potentielle (a + b) (82,7%) que les fourrages tropicaux Pennisetum purpureum (64,9%) et Tripsacum laxum (66,8%) mais moindre que les fourrages tempérés (Lolium perenne : 90,5%). Festuca arundinacea a présenté une production élevée de propionate (234.7 Gmol/mmol AGV totaux).Conclusion : Les meilleurs de la collection de 24 écotypes de F. arundinacea ont été identifiés pour une utilisation comme aliment pour bétail. Les teneurs en MAT trouvées pour la fétuque élevée sont comparables à celles des fourrages tropicaux qui sont généralement plus pauvres en protéine que les fourrages tempérés ; ce qui représente un handicap pour leur ingestion volontaire. Ces résultats impliquent d’une part qu’il faut une supplémentation en azote pour les pâturages de Festuca arundinacea et d’autre part l’exploitation des pâturages à la fétuque élevée au stade avant frutification. Par ailleurs, la culture en association de fétuque élevée et légumineuses est également une solution envisageable. Une variabilité a été notée entre les écotypes de Festuca arundinacea qui en moyenne présentent une meilleure dégradabilité que les fourrages tropicaux, mais moindres que les fourrages tempérés. Cet avantage de la fétuque élevée sur les fourrages tropicaux se consolide par une production élevée d’acide propionique et faible d’acide acétique comparables à celles des fourrages tempérés ; ce qui est très intéressant car le propionate peut générer du glucose, un des facteurs limitant pour la production laitière.Mots clés: Festuca arundinacea, écotype, azote ammoniacal, dégradabilité in sacco, méthane, acides gras volatile

Checking the Polarity of Superconducting Multipole LHC Magnets

This paper describes the design and operation of the âﾜPolarity Checkerâ, a scanning probe designed to check multipole field order, type and polarity of superconducting LHC magnets. First we introduce the measurement method, based on the harmonic analysis of the radial field component picked up by a rotating Hall sensor at different current levels. Then we describe the hardware and the software of the system, which features automatic powering, data acquisition and treatment, discussing the achieved sensitivity and performance. Finally we provide a summary of the test results on the first 505 cryoassemblies, showing how the system was usefully employed to detect some potentially harmful connection errors

Plant viruses.

Clover viruses, 82ES38, 82AL47, 82MA19, 82BR19, 82BY29; 82BU5, 82HA9. Lupin virus, diseases. Barley yellow dwarf virus, 82AL46, 82AL51, 82B10, 82BA33, 82BR16, 82BR18, 82C29, 82E27, 82ES37, 82ES40, 82JE19, 82JE20, 82KA33, 82KA34, 82ABI3, 82MA18, 82MN22, 82MT34, 82NA32, 82WH28,82B8, 82MN17, 82E24, 82MT30, 82E25, 82MN18, 82MT31, 82B9, 82ABI2, 82BA31, 82C26, 82JE17, 82WH27, 82AL45, 82BR17, 82ES39, 82MA1, 82MA117, 82MT33

Crop Updates 2000 Cereals - part 3

This session covers eighteen papers from different authors: BARLEY AND OAT AGRONOMY 1. Unicorn barley must meet malting specifications to be a viable option, Roslyn Jettnerand Blakely Paynter, Agriculture Western Australia 2. Optimum oat seed rates, Glenn McDonald, Agriculture Western Australia 3. Production and Quality of export Oaten Hay (1998 and 1989), Pierre Fievez, Pierre Fievez and Associates FROST 4. Climatology of Frost in Southern Western Australia, Ian Foster, Agriculture Western Australia 5. Flowering calculator, David Tennant, Agriculture Western Australia 6. Some options for managing the risk of frost damage, Wal Anderson, Agriculture Western Australia PASTURE 7. TIMERITE® Control of redlegged earth mite in south western Australia with a spring spray to pastures, James Ridsdill-Smith and Celia Pavri, CSIRO Entomology, University of Western Australia 8. The pattern of seed softening in subterranean clover in relation to presicted false break risk, Ross Chapman and Senthold Asseng, CSIRO Plant Industry, Centre for Mediterranean Agricultural Research 9. Charano serradella – a viable option for 1:1 cropping, Steve Carr and Brad Nutt IAMA Agri-Services Western Australia and Centre for Legumes in Mediterranean Agriculture, University of Western Australia 10. Alfalfa mosaic virus in alternative annual pasture and forage legumes, Lindrea Latham and Roger Jones, Crop Improvement Institute, Agriculture Western Australia and Centre for Legumes in Mediterranean Agriculture, University of Western Australia 11. Pasture mixture performs better than single-species-based pasture – 1999, Anyou Liu, Clinton Revell and David Ferris, Centre for Cropping Systems, Agriculture Western Australia 12. Better pasture management improves performance of following crops – 1999, Anyou Liu, Clinton Revell and David Ferris, Centre for Cropping Systems, Agriculture Western Australia 13. Lucerne Benefits Crop Production, Roy Latta1, Lisa-Jane Blacklow2, Chris Matthews1 1Agriculture Western Australia 2University of Western Australia 14. Does size count? Determining optimum release number of red apion for biocontrol of doublegee, Tim Woodburn and Paul Yeoh, CSIRO Entomology/CRC Weed Management Systems, Perth 15. Herbicide tolerance of some new cultivars of annual pasture legumes, Clinton Revell and Ian Rose, Centre for Cropping Systems, Agriculture Western Australia 16. Lucerne – crop rotations in the Esperance region, Anita Lyons, Roy Latta and Chris Matthews,Agriculture Western Australia PRECISION AGRICULTURE 17. Assessing the results of on-farm experiments using yield monitors, Simon Cook and Matthew Adams, CSIRO Land and Water 18. Achiever: A GIS based achievable yield and fertiliser recommendation system for precision agriculture, Robert J. Corner, Matthew L. Adams, Precision Agriculture Research Group CSIRO Land and Wate

Synthetic Nanoparticles for Vaccines and Immunotherapy

The immune system plays a critical role in our health. No other component of human physiology plays a decisive role in as diverse an array of maladies, from deadly diseases with which we are all familiar to equally terrible esoteric conditions: HIV, malaria, pneumococcal and influenza infections; cancer; atherosclerosis; autoimmune diseases such as lupus, diabetes, and multiple sclerosis. The importance of understanding the function of the immune system and learning how to modulate immunity to protect against or treat disease thus cannot be overstated. Fortunately, we are entering an exciting era where the science of immunology is defining pathways for the rational manipulation of the immune system at the cellular and molecular level, and this understanding is leading to dramatic advances in the clinic that are transforming the future of medicine.1,2 These initial advances are being made primarily through biologic drugs– recombinant proteins (especially antibodies) or patient-derived cell therapies– but exciting data from preclinical studies suggest that a marriage of approaches based in biotechnology with the materials science and chemistry of nanomaterials, especially nanoparticles, could enable more effective and safer immune engineering strategies. This review will examine these nanoparticle-based strategies to immune modulation in detail, and discuss the promise and outstanding challenges facing the field of immune engineering from a chemical biology/materials engineering perspectiveNational Institutes of Health (U.S.) (Grants AI111860, CA174795, CA172164, AI091693, and AI095109)United States. Department of Defense (W911NF-13-D-0001 and Awards W911NF-07-D-0004

Computational Identification of Transcriptional Regulators in Human Endotoxemia

One of the great challenges in the post-genomic era is to decipher the underlying principles governing the dynamics of biological responses. As modulating gene expression levels is among the key regulatory responses of an organism to changes in its environment, identifying biologically relevant transcriptional regulators and their putative regulatory interactions with target genes is an essential step towards studying the complex dynamics of transcriptional regulation. We present an analysis that integrates various computational and biological aspects to explore the transcriptional regulation of systemic inflammatory responses through a human endotoxemia model. Given a high-dimensional transcriptional profiling dataset from human blood leukocytes, an elementary set of temporal dynamic responses which capture the essence of a pro-inflammatory phase, a counter-regulatory response and a dysregulation in leukocyte bioenergetics has been extracted. Upon identification of these expression patterns, fourteen inflammation-specific gene batteries that represent groups of hypothetically ‘coregulated’ genes are proposed. Subsequently, statistically significant cis-regulatory modules (CRMs) are identified and decomposed into a list of critical transcription factors (34) that are validated largely on primary literature. Finally, our analysis further allows for the construction of a dynamic representation of the temporal transcriptional regulatory program across the host, deciphering possible combinatorial interactions among factors under which they might be active. Although much remains to be explored, this study has computationally identified key transcription factors and proposed a putative time-dependent transcriptional regulatory program associated with critical transcriptional inflammatory responses. These results provide a solid foundation for future investigations to elucidate the underlying transcriptional regulatory mechanisms under the host inflammatory response. Also, the assumption that coexpressed genes that are functionally relevant are more likely to share some common transcriptional regulatory mechanism seems to be promising, making the proposed framework become essential in unravelling context-specific transcriptional regulatory interactions underlying diverse mammalian biological processes