Acid-induced aggregation and gelation of heat-treated chia proteins

This work studied for the first time the acid-induced aggregation and gelation of heat-treated chia protein isolates obtained by extraction at pH 10 or 12 (CPI10 and CPI12, respectively). The aggregation state of proteins was modified during acidification. The size of the aggregates was reduced for both samples when the pH decreased but below pH 4.5 further protein aggregation took place for CPI12. Gelation of CPI12 was completed after about 30 min of acidification with glucone-δ-lactone. By contrast, this period was not enough to reach a constant value in G′ for CPI10. When gelation was ensured, confocal laser scanning micrographs from those gels revealed a coarse and irregular structure with large pores (median size of diameters: 30 μm). Instead, micrographs from CPI12 cold gels showed a more regular and interconnected network, with smaller pores (median size of diameters: 9 μm). These differences are consistent with a higher elastic behaviour ((Formula presented.) = 13.6 ± 0.1 Pa).Fil: López, Débora Natalia. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química y Física. Área Fisicoquímica; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Facultad de Química e Ingeniería-Rosario; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; ArgentinaFil: Ingrassia, Romina. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química y Física. Área Fisicoquímica; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; ArgentinaFil: Busti, Pablo Andres. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química y Física. Área Fisicoquímica; ArgentinaFil: Wagner, Jorge Ricardo. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Boeris, Valeria. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química y Física. Área Fisicoquímica; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Facultad de Química e Ingeniería-Rosario; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; ArgentinaFil: Spelzini, Darío. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Departamento de Química y Física. Área Fisicoquímica; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Facultad de Química e Ingeniería-Rosario; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; Argentin

Liver segmentation in MRI: a fully automatic method based on stochastic partitions

There are few fully automated methods for liver segmentation in magnetic resonance images (MRI) despite the benefits of this type of acquisition in comparison to other radiology techniques such as computed tomography (CT). Motivated by medical requirements, liver segmentation in MRI has been carried out. For this purpose, we present a new method for liver segmentation based on the watershed transform and stochastic partitions. The classical watershed over-segmentation is reduced using a marker-controlled algorithm. To improve accuracy of selected contours, the gradient of the original image is successfully enhanced by applying a new variant of stochastic watershed. Moreover, a final classifier is performed in order to obtain the final liver mask. Optimal parameters of the method are tuned using a training dataset and then they are applied to the rest of studies (17 datasets). The obtained results (a Jaccard coefficient of 0.91 +/- 0.02) in comparison to other methods demonstrate that the new variant of stochastic watershed is a robust tool for automatic segmentation of the liver in MRI. (C) 2014 Elsevier Ireland Ltd. All rights reserved.This work has been supported by the MITYC under the project NaRALap (ref. TSI-020100-2009-189), partially by the CDTI under the project ONCOTIC (IDI-20101153), by Ministerio de Educacion y Ciencia Spain, Project Game Teen (TIN2010-20187) projects Consolider-C (SEJ2006-14301/PSIC), "CIBER of Physiopathology of Obesity and Nutrition, an initiative of ISCIII" and Excellence Research Program PROMETEO (Generalitat Valenciana. Conselleria de Educacion, 2008-157). We would like to express our gratitude to the Hospital Clinica Benidorm, for providing the MR datasets and to the radiologist team of Inscanner for the manual segmentation of the MR images.López-Mir, F.; Naranjo Ornedo, V.; Angulo, J.; Alcañiz Raya, ML.; Luna, L. (2014). Liver segmentation in MRI: a fully automatic method based on stochastic partitions. Computer Methods and Programs in Biomedicine. 114(1):11-28. https://doi.org/10.1016/j.cmpb.2013.12.022S1128114

Engineering the microstructure and magnetism of La2_2CoMnO6_6 thin films by tailoring oxygen stoichiometry

We report on the magnetic and structural properties of ferromagnetic-insulating La$_2$CoMnO$_6$ thin films grown on top of (001) STO substrates by means of RF sputtering technique. Careful structural analysis, by using synchrotron X-ray diffraction, allows identifying two different crystallographic orientations that are closely related to oxygen stoichiometry and to the features (coercive fields and remanence) of the hysteresis loops. Both Curie temperature and magnetic hysteresis turn out to be dependent on the oxygen stoichiometry. In situ annealing conditions allow tailoring the oxygen content of the films, therefore controlling their microstructure and magnetic properties

La Oficina de Farmacia: una herramienta para conocer el grado de adherencia a la dieta mediterránea de la población

Objetivos: Evaluar el grado de adherencia a la dieta mediterránea y el IMC de individuos mayores de 40 años a través de las Oficinas de Farmacia y ver la influencia que tienen la edad, status socioeconómico y estado civil sobre el mismo. Métodos: 291 personas (130 hombres y 161 mujeres) distribuidos por intervalo de edad, en tres etapas de transición madura: 40-50 años (inicial), 50-60 años (media) y 60- 70 años (avanzada). Los datos fueron recolectados en unas oficinas de farmacia por medio de tres encuestas: aspectos sociodemograficos, variables antropométricas y valoración de la adherencia. Resultados: De acuerdo al IMC, el 62,4% de las personas encuestadas se clasificaron en situación de sobrepeso y el 37,6% en situación de normopeso. Las personas entre 40-50 años presentaban un valor medio de adherencia al patrón de dieta mediterránea de 7,8 (IC95%:7,7-7,9); los de 50-60 años de 8,3 (IC95%: 8,1-8,5) y los de 60-70 años de 11,4 (IC95%: 11,7-11,1). Conclusiones: No existen diferencias estadísticas significativas entre las condiciones socioeconómicas y estado civil en cuanto al IMC y grado de adherencia al patrón de dieta mediterránea. No sucede lo mismo en cuanto a la edad, entre 40-60 años no alcanzan las recomendaciones de consumo de la mayoría de los alimentos que constituyen la base de la alimentación mediterránea. El mayor grado de adherencia está en la población entre 60-70 años. El farmacéutico mediante unas sencillas encuestas puede detectar estas desviaciones y dar los consejos nutricionales adecuados para restablecer el patrón mediterráneo.Aim: To assess Mediterranean diet adherence and BMI in people over 40 years of age using a community pharmacy, and the influences of age, socioeconomic status and marital status. Methods: 291 people (130 men and 161 women) distributed in three age group: 40-50 years, 50-60 years and 60-70 years. The data were collected in several community pharmacies through three questionnaires about sociodemographic factors, anthropometric measurements and adherence to Mediterranean diet. Results: According to BMI, 62.4% of people were overweight and 37.6% normal weight. The mean Mediterranean diet adherence levels were 7.8 (95% CI :7,7-7,9) in the 40-50 year range, 8.3 (95% CI : 8,1-8,5) in the 50-60 year range and 11,4 (95% CI : 11,7-11,1) in the 60-70 year range. Conclusions: There are no statistically significant differences between socioeconomic status and marital status regarding BMI or Mediterranean diet adherence. However, this is not the case when the age variable is taken into account, as people in the 40-60 year range do not follow the recommendations of food consumption for the Mediterranean diet. The highest level of adherence is in people aged 60-70 years. Using simple questionnaires community pharmacists could reveal this low adherence and give adequate nutritional advice to reinforce Mediterranean diet adherence.El estudio se ha realizado con los medios habituales de que dispone el Departamento de Nutrición y Bromatología y a través de los recursos aportados por el Máster Universitario en Atención Farmacéutica (EuropharmNES) de la Universidad de Granada

Revisión bibliográfica de implantología bucofacial del año 2009. 2ª parte

Debido al amplio número de publicaciones que existen sobre Implantología Bucofacial, resulta difícil para el odontólogo seleccionar y leer de forma crítica una cantidad suficiente de artículos que puedan aportarle una información útil para su praxis diaria. En este artículo pretendemos sintetizar la información más relevante que se encuentra en las revistas indexadas de la especialidad publicadas el año 2009

Revisión bibliográfica de implantología bucofacial del año 2009. 2ª parte

Debido al amplio número de publicaciones que existen sobre Implantología Bucofacial, resulta difícil para el odontólogo seleccionar y leer de forma crítica una cantidad suficiente de artículos que puedan aportarle una información útil para su praxis diaria. En este artículo pretendemos sintetizar la información más relevante que se encuentra en las revistas indexadas de la especialidad publicadas el año 2009

Revisión bibliográfica de implantología bucofacial del año 2009. 1ª parte

Debido al amplio número de publicaciones que existen sobre Implantología Bucofacial, resultadifícil para el odontólogo seleccionar y leer de forma crítica una cantidad suficiente de artículos que puedan aportarle una información útil para su praxis diaria. En este artículo se pretende sintetizar la información más relevante que se encuentra en las revistas indexadas de la especialidad publicadas durante el año 2009

MAGIC observations of MWC 656, the only known Be/BH system

Context: MWC 656 has recently been established as the first observationally detected high-mass X-ray binary system containing a Be star and a black hole (BH). The system has been associated with a gamma-ray flaring event detected by the AGILE satellite in July 2010. Aims: Our aim is to evaluate if the MWC 656 gamma-ray emission extends to very high energy (VHE > 100 GeV) gamma rays. Methods. We have observed MWC 656 with the MAGIC telescopes for $\sim$23 hours during two observation periods: between May and June 2012 and June 2013. During the last period, observations were performed contemporaneously with X-ray (XMM-Newton) and optical (STELLA) instruments. Results: We have not detected the MWC 656 binary system at TeV energies with the MAGIC Telescopes in either of the two campaigns carried out. Upper limits (ULs) to the integral flux above 300 GeV have been set, as well as differential ULs at a level of $\sim$5% of the Crab Nebula flux. The results obtained from the MAGIC observations do not support persistent emission of very high energy gamma rays from this system at a level of 2.4% the Crab flux.Comment: Accepted for publication in A&A. 5 pages, 2 figures, 2 table

Present and Future of Parkinson’s Disease in Spain: PARKINSON-2030 Delphi Project

Parkinson's disease (PD) is a chronic progressive and irreversible disease and the second most common neurodegenerative disease worldwide. In Spain, it affects around 120.000-150.000 individuals, and its prevalence is estimated to increase in the future. PD has a great impact on patients' and caregivers' lives and also entails a substantial socioeconomic burden. The aim of the present study was to examine the current situation and the 10-year PD forecast for Spain in order to optimize and design future management strategies. This study was performed using the modified Delphi method to try to obtain a consensus among a panel of movement disorders experts. According to the panel, future PD management will improve diagnostic capacity and follow-up, it will include multidisciplinary teams, and innovative treatments will be developed. The expansion of new technologies and studies on biomarkers will have an impact on future PD management, leading to more accurate diagnoses, prognoses, and individualized therapies. However, the socio-economic impact of the disease will continue to be significant by 2030, especially for patients in advanced stages. This study highlighted the unmet needs in diagnosis and treatment and how crucial it is to establish recommendations for future diagnostic and therapeutic management of PD