Abordaje diagnóstico, terapéutico y seguimiento de las lesiones pre malignas de Cérvix en pacientes de los Municipios del Departamento de Boaco, atendidas en el Hospital José Nieborowski en período correspondiente de Enero 2016-Mayo 2017

El presente estudio es descriptivo, retrospectivo de corte transversal, que se realizó en el Hospital José Nieborowski, en donde se atendieron 305 mujeres con lesiones de bajo grado de cervical en todo el año 2016 , de la cual se extrajo una muestra significativa de 90 pacientes procedentes de diferentes munición del departamento de Boaco, con el objetivo de la aplicación del siguiente tema Abordaje diagnóstico, terapéutico y seguimiento de las lesiones pre malignas de cérvix en pacientes de los municipios del departamento de Boaco, atendidas en el hospital José Nieborowsk en periodo correspondiente de Enero 2016 Mayo 2017. Obteniendo siguientes resultados Las pacientes en estudio son mujeres que predominaron de mayor de 35 años, estos resultados se relacionan, con los diferentes estudios, en donde comienzan a parecer las alteraciones histológicas de cérvix, pero sin embargo no podemos obviar que se encontró lesiones en mujeres en edad reproductiva, amas de casa, con educación secundaria y primaria y de procedencia urbana. Entre los factores asociados de las pacientes estudiadas se encontró que el nivel de escolaridad baja, inicio de vida sexual a temprana edad más de un compañero sexual, el uso de anticonceptivos hormonales, la multiparidad, Como método de tamizaje se utilizó el PAP y de diagnóstico la biopsia cervical, encontrando que las lesiones más frecuentes son las de bajo grado como lo es el NIC1, seguidas por las de alto grado. Las lesiones de bajo grado VPH se les dio seguimiento citológico evolucionaron con regresión espontanea, las lesiones NIC I fueron tratadas con crioterapia, las lesiones de alto grado (NIC II y NIC III) el tratamiento de elección ASA Térmica, y en algunos casos se realizó histerectomía según criterios médico

Mean field theory of chaotic insect swarms

The harmonically confined Vicsek model displays qualitative and quantitative features observed in natural insect swarms. It exhibits a scale-free transition between single and multicluster chaotic phases. Finite-size scaling indicates that this unusual phase transition occurs at zero confinement [Phys. Rev. E 107, 014209 (2023)]. While the evidence of the scale-free-chaos phase transition comes from numerical simulations, here we present its mean-field theory. Analytically determined critical exponents are those of the Landau theory of equilibrium phase transitions plus dynamical critical exponent z = 1 and a new critical exponent φ = 0.5 for the largest Lyapunov exponent. The phase transition occurs at zero confinement and noise in the mean-field theory. The noise line of zero largest Lyapunov exponents informs observed behavior: (i) the qualitative shape of the swarm (on average, the center of mass rotates slowly at the rate marked by the winding number and its trajectory fills compactly the space, similarly to the observed condensed nucleus surrounded by vapor) and (ii) the critical exponents resemble those observed in natural swarms. Our predictions include power laws for the frequency of the maximal spectral amplitude and the winding number.This work has been supported by the FEDER/Ministerio de Ciencia, Innovación y Universidades-Agencia Estatal de Investigación Grants No. PID2020-112796RB-C21 ( R.G.-A.) and No. PID2020-112796RB-C22 (L.L.B.), by the Madrid Government (Comunidad de Madrid-Spain) under the Multiannual Agreement with UC3M in the line of Excellence of University Professors (EPUC3M23), and in the context of the V PRICIT (Regional Programme of Research and Technological Innovation). R.G.-A. acknowledges support from the Ministerio de Economía y Competitividad of Spain through the Formación de Doctores program Grant No. PRE2018-083807 cofinanced by the European Social Fund

Arquitectura defensiva en el Castro de Castromaior (Lugo). Análisis de las técnicas constructivas en el acceso al recinto central del poblado

The analysis of the building techniques of the pre-Roman fort of Castromaior (Lugo) is here presented. The archaeological methodology is employed from an analytical point of view by means of the systematic archaeological excavation and in order to obtain a hypothetical reconstruction of one of the access to the village. Stratigraphical analysis and excavation have together revealed enough results to identify different building phases. After a brief description of the site, the results are analysed archaeologically, focusing the attention on the architecture belonging to the demarcation structures. Once analysed the results, a reconstruction of the access area is proposed. This brief work offers a new vision of the pre-Roman forts in the northwestern area of the Iberian Peninsula based on the analysis of the architecture of demarcation.Se presenta un análisis de técnicas constructivas en el castro prerromano de Castromaior (Lugo), donde se utiliza la metodología arqueológica desde un punto de vista analítico, a través de la excavación sistemática, para llegar a una reconstrucción hipotética de uno de los accesos al poblado. La lectura estratigráfica y la excavación han proporcionado suficientes datos para poder diferenciar fases constructivas. Tras una breve presentación del yacimiento se analizarán los resultados a nivel arqueológico, centrando el estudio en la arquitectura de las estructuras de delimitación. Una vez analizados los resultados, se proyecta una reconstrucción de la zona de entrada. Este pequeño estudio presenta una nueva visión de la edilicia castreña en el noroeste peninsular enfocada desde el punto de vista de la arquitectura de delimitación

Aphasia with anatomical isolation of the language area: A reanalysis on the light of modern neuroimaging techniques

Introduction : Goldstein (1948) and Geschwind (1968), based in data derived from anatomical post-mortem studies, postulated that the disconnection of the perisylvian language areas (PSLA) from other cortical areas was responsible for impairments in spontaneous speech and language comprehension with preservation of verbal repetition and echolalia (isolation of speech area). Nevertheless, other mechanisms (right hemisphere or bilateral hypotheses) underlying echolalic repetition have been proposed. Herein, we examined the structure and function of the PSLAs in two cases of aphasia with echolalic repetition and isolation of the left PSLA. Methods : Two patients with chronic post-stroke aphasia associated to isolation of the left PSLA were studied. Both patients underwent cognitive-language assessment and multimodal imaging. In patient 1 (p1), structural MRI, diffusion tensor imaging (DTI), functional MRI (fMRI) during repetition of words and non-words, resting state fMRI (rsfMRI) were acquired, whereas only structural MRI was performed in patient 2 (p2). The Tractotron software was used to examine the severity of disconnection in each language-related white matter tract in both patients. We quantified the severity of the disconnection by measuring the proportion of each tract that was affected. 18FDG-PET was also acquired in both patients. Results : P1 had a mixed transcortical aphasia and p2 had a transcortical sensory/anomic aphasia. In both, the MRI showed separate left anterior and posterior lesions with relative preservation of the PSLA. In both, 18FDG-PET revealed significant decrements of metabolic activity in areas of the left PSLA, although some parts showed normal metabolic activity. In p1 the left arcuate fasciculus (AF) and the inferior fronto-occipital fasciculi (IFOF) could not be reconstructed. fMRI showed perilesional activity in the left hemisphere and increased activity in the right during word repetition. rsfMRI showed compensatory activity in both hemispheres (right greater than left). Analysis with the Tractotron software revealed disconnection of both the AF and the IFOF in the left hemisphere of both patients. Discussion : Although some parts of the left PSLA had preserved metabolic activity in both patients, our neuroimaging data revealed that preserved repetition ability did not rely exclusively on the residual activity of the left PSLA. In support, the connectivity between different components of the left PSLA was severely affected. This coupled with the increased metabolic activity of the right PSLA supports the bilateral hypothesis of residual repetition in transcortical aphasias. References : Goldstein, K. (1948). Language and Language Disturbances. Geschwind, et al. (1968). Neuropsychologia 6, 327–340.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

A methodology for the classification of gravel beaches

Beaches are highly flexible structures that can be deformed by several reasons, some natural as wind and swell and others not, as human actions. Gravel, considered as a component of the beach is not always separated from the rest of the materials. It is a part of the coastline sedimentary balance, usually with time and spatial scales much greater than those corresponding to the stretch of the coast under study. The conceptual and experimental difficulties of studying this kind of beach have meant that nowadays they are really unknown. In this paper, methodologies to classify and determinate the most important characteristics in gravel beaches are presented. The authors have studied 34 shingle beaches in the region of Alicante (Spain) from a database with their characteristics. Obtained data corresponds to the morphology of the beach, the materials that take part in its composition and the wave energy, considering its incidence, the wave height, the local period and its influence on the coastline. At the beginning, mathematical models are generated, allowing the expression of the relationships between the slope of berm and the rest of variables. To classify the beaches, a factor analysis has been used on the experimental data matrix, considering all the variables as predictive, obtaining in this way an index for beach classification with similar characteristics. Furthermore, to determine the predictive variables that allow characterizing the 34 beaches, a discriminant analysis has been applied over several sets of variables. In each case, a predictive model of cluster belonging is created, considering a discriminant function, and with the clustering function formed by different clusters. The methodologies developed in this paper will be applied later to other beaches as classification and variable selection methods

Link layer Connectivity as a Service for Ad-hoc Microservice Platforms

Microservice platforms have brought many advantages to support the deployment of light-weight applications at both near the edge and data centers. Still, their suitability to support telecommunication and vertical services beyond the network edge is far from being a reality. On one hand, their flat networking approach does not support the establishment of link-layer connectivity among the different components of telecommunication and vertical services (e.g., access points, routers, specific-purpose servers, etc.) due to their reliance on high-level APIs. On the other hand, their networking approach has not been designed to operate over ad hoc networks built by the resource-constrained devices that may be available beyond the network edge. This can lead to suboptimal behaviors for the delivery of data traffic between microservices. This article presents the results of a research collaboration between Universidad Carlos III of Madrid and Telefónica: L2S-M. Our solution provides a programmable data plane that enables the establishment of on-demand link layer connectivity between microservices on ad hoc networks. This solution has the flexibility to execute different algorithms to build traffic paths between microservices, as well as to react against temporary link breakdowns, which could be present in these types of networks. The article presents a proof of concept for a functional validation of L2S-M, using an aerial ad hoc network deployed at 5TONIC Laboratory in collaboration with Telefonica. The validation results showcase the proper operation of L2S-M as a networking service for microservice platforms in ad hoc networks, including its ability to reconfigure the programmable data plane when link disruptions occur.This article has been supported by the TRUE5G (PID2019-108713RB681) project funded by the Spanish National Research Agency (MCIN/AEI/10.13039/5011000110) and by the H2020 FISHY Project (Grant agreement ID: 952644)

Galerkin's formulation of the finite elements method to obtain the depth of closure

Coastal erosion and lack of sediment supply are a serious global problem. It is therefore necessary to determine the depth of closure (DoC) of a beach—key parameter in the calculation of the sand volume and the location of the beach protection elements—in a precise way. For this reason, this work generates a numerical model based on Galerkin's formulation of finite elements that provides sufficient precision for the determination of DoC with a minimum investment. Thus, after the generation of three models in which the difference was the dependent variables, the least complex has been chosen. It is composed of the variables: median sediment size, wave height and period associated with the mean flow, as well as the angle that the mean flow forms with respect to the studied profile in absolute value (α). The selected model has been compared with the most commonly used models currently in use, having an average absolute error of 0.36 m and an average MAPE of 70% over current models. In addition, it presents a high stability, since after the random disturbance of all the input variables (up to 5%), the model error remains stable, increasing the MAPE by a maximum of 7.4% and the average absolute error by 0.15 m. Therefore, it is possible to use the model to infer the DoC in other study areas where the values of the variables are similar to those studied here, although the selected method can be extrapolated to other parts of the world.This work was partially supported by the Universidad de Alicante through the project “Estudio sobre el perfil de equilibrio y la profundidad de cierre en playas de arena” (GRE15-02)

Treatment of temporomandibular myofascial pain with deep dry needling

Objectives: The present study was designed to evaluate the usefulness of deep dry needling in the treatment of temporomandibular myofascial pain. Study D esign: We selected 36 patients with myofascial pain located in the external pterygoid muscle (30 women/6 men, mean age=27 years with SD±6,5). We studied differences in pain with a visual analog scale and range of mandibular movements before and after intervention. Results: We found a statistically significant relationship (p<0,01) between therapeutic intervention and the improvement of pain and jaw movements, which continued up to 6 months after treatment. Pain reduction was greater the higher was the intensity of pain at baseline. Conclusions: Although further studies are needed, our findings suggest that deep dry needling in the trigger point in the external pterygoid muscle can be effective in the management of patients with myofascial pain located in that muscle

Co-manejo de una especie de alto valor con derechos de uso territorial para la pesca: un enfoque bioeconómico espacial con variabilidad ambiental

Abalone is a high-value resource that is an important export market fishery of Mexico that is managed through territorial use rights for fisheries allocated to a coastal community. A specific age-structured spatial bioeconomic model was applied to this fishery to undertake stock recovery to target levels. The model incorporates uncertainty in the parameter&nbsp;k&nbsp;of a von Bertalanffy growth function with environmental variability. The risk of falling below and exceeding the target and bioeconomic limit reference points of the population with alternative fisheries management strategies was studied using a Monte Carlo analysis. The management strategy evaluation showed that Emin&nbsp;(minimum effort) and EmaxNPV&nbsp;(resource rent maximization effort) generated higher biomass levels and higher present value of resource rent than Emsy&nbsp;(effort in maximum sustainable yield) at the end of the simulation period, regardless of the bioeconomic reference points and assuming a reduction in fishing effort. Emin&nbsp;and EmaxNPV&nbsp;increased and maximized the present value of resource rent generated by the species while avoiding its overexploitation. The social consequences of the management strategies were considered with the participation of fishers of this co-managed fishery.El abulón es un recurso de alto valor que constituye un importante mercado de exportación pesquera en México, gestionado a través de derechos de uso territorial para la pesca (TURF) asignados a una comunidad costera. Se aplicó un modelo bioeconómico espacial específico estructurado por edades a esta pesquería para llevar a cabo la recuperación de las poblaciones hasta niveles objetivos. El modelo incorpora la incertidumbre en el parámetro&nbsp;k&nbsp;de la Función de Crecimiento de von Bertalanffy con variabilidad ambiental. Se realizó un análisis de Monte Carlo para evaluar el riesgo de caer por debajo o superar los puntos de referencia bioeconómicos objetivo y límite de la población con estrategias alternativas de manejo pesquero. La evaluación de las estrategias de manejo mostró que Emin&nbsp;(esfuerzo mínimo) y EmaxNPV&nbsp;(maximización de la renta que genera el recurso) en comparación con Emsy&nbsp;(esfuerzo en el rendimiento máximo sostenible) son estrategias que generan niveles de biomasa más altos y un mayor valor presente de la renta que genera el recurso al final del período de simulación. Independientemente de los puntos de referencia bioeconómicos, las estrategias que presentaron las mejores condiciones fueron Emin&nbsp;y EmaxNPV, asumiendo una reducción en el esfuerzo pesquero, aumentando y maximizando el valor presente de la renta del recurso generado por la especie al evitar su sobreexplotación. Se consideraron las consecuencias sociales de las estrategias de manejo con la participación de los pescadores de esta pesquería co-gestionada

Identification of the water stress level in olive trees during pit hardening using the trunk growth rate indicator.

Water scarcity is generating an increasing interest in deficit irrigation scheduling. The trunk diameter fluctuations are daily cycles that have been suggested as tools for irrigation scheduling. The trunk growth rate (TGR) was suggested as the best indicator for olive trees during pit hardening. The aim of this work is to clarify how the TGR could be used to identify water stress levels. The experiment was performed during the 2017 season, in a commercial, super-high-density orchard in Carmona (Seville, Spain). Four different irrigation treatments were performed according to midday stem water potential values and TGR. The data obtained were very variable and both indicators presented a wide range of water status throughout the season. The maximum trunk diameter data clearly showed the pattern of the trees water status but the comparison between treatments and the identification of the water stress level was not possible. The average TGR was linked to the midday stem water potential, but with a minimum amount of data. Irrigation scheduling based on the average TGR was difficult because of the great increases in some daily TGR values. For clarity, the pool of data was grouped by midday stem water potential. These water stress levels were characterized using the weekly frequency of TGR values. The increase of water stress reduced the frequency of values between -0.1 and 0.3mm day-1 from 60% to less than 25%. Moderate water stress levels increased the percentage of values lower than -0.3mm day-1 from 7% to 37%. The most severe water stress conditions increased the TGR values between -0.3 and -0.1mm day-1 from 16% up to 22%.IRNASINSTITUTO DE LA GRASACSI