Power quality in high-tech campus: an exemplary case study

This paper presents preliminary results from a power quality audit conducted at a high-tech campus over last year. Voltage and current were measured at various R&D buildings. The paper examines the causes and effects of power disturbances that affect computer or any other microprocessor based equipment and analyses the auto-protection capabilities of modern power supplies. The convenience of “enhanced power supply” or “low-cost customer-side” protection solutions is also discussed. Finally it is addressed the role of the Standards on the protection of electronic equipment and the implications for the final costume

Collaborative explicit plasticity framework: a conceptual scheme for the generation of plastic and group-aware user interfaces

The advent of new advances in mobile computing has changed the manner we do our daily work, even enabling us to perform collaborative activities. However, current groupware approaches do not offer an integrating and efficient solution that jointly tackles the flexibility and heterogeneity inherent to mobility as well as the awareness aspects intrinsic to collaborative environments. Issues related to the diversity of contexts of use are collected under the term plasticity. A great amount of tools have emerged offering a solution to some of these issues, although always focused on individual scenarios. We are working on reusing and specializing some already existing plasticity tools to the groupware design. The aim is to offer the benefits from plasticity and awareness jointly, trying to reach a real collaboration and a deeper understanding of multi-environment groupware scenarios. In particular, this paper presents a conceptual framework aimed at being a reference for the generation of plastic User Interfaces for collaborative environments in a systematic and comprehensive way. Starting from a previous conceptual framework for individual environments, inspired on the model-based approach, we introduce specific components and considerations related to groupware

Perinatal exposure to pesticides alters synaptic plasticity signaling and induces behavioral deficits associated with neurodevelopmental disorders.

Increasing evidence from animal and epidemiological studies indicates that perinatal exposure to pesticides cause developmental neurotoxicity and may increase the risk for psychiatric disorders such as autism and intellectual disability. However, the underlying pathogenic mechanisms remain largely elusive. This work was aimed at testing the hypothesis that developmental exposure to different classes of pesticides hijacks intracellular neuronal signaling contributing to synaptic and behavioral alterations associated with neurodevelopmental disorders (NDD). Low concentrations of organochlorine (dieldrin, endosulfan, and chlordane) and organophosphate (chlorpyrifos and its oxon metabolite) pesticides were chronically dosed ex vivo (organotypic rat hippocampal slices) or in vivo (perinatal exposure in rats), and then biochemical, electrophysiological, behavioral, and proteomic studies were performed. All the pesticides tested caused prolonged activation of MAPK/ERK pathway in a concentration-dependent manner. Additionally, some of them impaired metabotropic glutamate receptor-dependent long-term depression (mGluR-LTD). In the case of the pesticide chlordane, the effect was attributed to chronic modulation of MAPK/ERK signaling. These synaptic alterations were reproduced following developmental in vivo exposure to chlordane and chlorpyrifos-oxon, and were also associated with prototypical behavioral phenotypes of NDD, including impaired motor development, increased anxiety, and social and memory deficits. Lastly, proteomic analysis revealed that these pesticides differentially regulate the expression of proteins in the hippocampus with pivotal roles in brain development and synaptic signaling, some of which are associated with NDD. Based on these results, we propose a novel mechanism of synaptic dysfunction, involving chronic overactivation of MAPK and impaired mGluR-LTD, shared by different pesticides which may have important implications for NDD.Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This work was supported by the Intertalentum Postdoctoral Program (Marie Curie cofund UAM-UE, EU project 713366) for V.B. and by grants from the Spanish Ministry of Science and Innovation (SAF2017-86983-R, PID2020-117651RB) and from the Spanish Ministry of Economy and Competitiveness (PCIN-2016– 095) for J.A.E.. V.B. was also recipient of the 2019 Eduardo Gallego postdoctoral fellowship from Fundación Francisco Cobos. M.I.C. was recipient of a postdoctoral fellowship from the Spanish Ministry of Economy (IJCI-2015–25507). E.LM. was recipient of a predoctoral fellowship from the Spanish Ministry of Science and Innovation (FPU18/02838).S

Investigation of the long effective conjugation length in defect-free insulated molecular wires

Due to the “insulation” of the π-conjugated backbones, insulated molecular wires (IMWs) are expected to be applied to various optoelectronic applications and nanotechnology.[1] Recently, Kazunori et al have succeeded in the synthesis of a self-threading polythiophene with a polyrotaxane-like 3D architecture (PSTB, see Figure 1), for which an intrawire hole mobility of 0.9 cm2 V−1 s−1 has been measured.[2] Here, we aim to evaluate the extent of π-conjugation along polythiophene backbones sheathed within defect-free “insulating” layers. A comparison between the experimental Raman spectra of the self-threading oligomers (i.e. 2STB-5STB) and the corresponding PSTB polymer indicates that: (i) the ratio of relative intensities of the two most intense Raman bands (I1375/1445) increases with the elongation of the size chain but does not saturate up to the pentamer, and (ii) π-conjugation spreads over 17–18 thiophene units in the polymer. Whether the effective conjugation length of the polymer is better described by using the long oligomer extrapolation approach[3] or periodic DFT calculations of the polymer is discussed in detailed by exploiting the very recent potentialities of state-of-the-art quantum chemical simulations of vibrational properties for crystalline solids.[Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Stabilization of high-order solutions of the cubic Nonlinear Schrodinger Equation

In this paper we consider the stabilization of non-fundamental unstable stationary solutions of the cubic nonlinear Schrodinger equation. Specifically we study the stabilization of radially symmetric solutions with nodes and asymmetric complex stationary solutions. For the first ones we find partial stabilization similar to that recently found for vortex solutions while for the later ones stabilization does not seem possible

Born too early and too small: higher order cognitive function and brain at risk at ages 8–16

Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear. We conducted a longitudinal study to first identify clinical predictors of ultrasound brain abnormalities in 196 children born very preterm (VP; gestational age 32 weeks) and with very low birth weight (VLBW; birth weight 1500 g). At ages 8–16, the subset of VP-VLBW children without neurological findings (124) were invited for a neuropsychological assessment and an MRI scan (41 accepted). Of these, 29 met a rigorous criterion for MRI quality and an age, and gender-matched control group (n = 14) was included in this study. The key findings in the VP-VLBW neonates were: (a) 37% of the VP-VLBW neonates had ultrasound brain abnormalities; (b) gestational age and birth weight collectively with hospital course (i.e., days in hospital, neonatal intensive care, mechanical ventilation and with oxygen therapy, surgeries, and retinopathy of prematurity) predicted ultrasound brain abnormalities. At ages 8–16, VP-VLBW children showed: a) lower intelligent quotient (IQ) and executive function; b) decreased gray and white matter (WM) integrity; (c) IQ correlated negatively with cortical thickness in higher order processing cortical areas. In conclusion, our data indicate that facets of executive function and IQ are the most affected in VP-VLBW children likely due to altered higher order cortical areas and underlying WMThis study was supported by the Spanish Government Institute Carlos III (FIS Pl11/02860), Spanish Ministry of Health to MM-L, and the University of Castilla-La Mancha mobility Grant VA1381500149

Estudio y Conservación del Patrimonio Cultural - Actas

Libro de Actas publicado por la organización del Congreso Nacional: Estudio y Conservación del Patrimonio Cultural - 2015Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Porosity-based models for estimating the mechanical properties of self-compacting concrete with coarse and fine recycled concrete aggregate

Predicting the mechanical properties of Self-Compacting Concrete (SCC) containing Recycled Concrete Aggregate (RCA) generally depends, in great part, on the RCA fraction in use. In this study, predictive equations for estimating SCC mechanical properties are developed through SCC porosity indices, so they are applicable to any RCA fraction and amount that may be used. A total of ten SCC mixes were prepared, nine of which containing different proportions of coarse and/or fine RCA (0%, 50% or 100% for both fractions), and the tenth mixed with 100% coarse and fine RCA, and RCA powder 0–1 mm. The following properties were evaluated: compressive strength, modulus of elasticity, splitting tensile strength, flexural strength, and effective porosity as measured with the capillary-water-absorption test. Negative effects on the above properties were recorded for increasing contents of both RCA fractions. The application of simple regression models yielded porosity-based estimations of the mechanical properties of the SCC with an accuracy margin of ±20%, regardless of the RCA fraction and amount. The results of the multiple regression models with compressive strength as a secondary predictive variable presented even greater robustness with accuracy margins of ±10% and almost no significant effect of accidental porosity variations on prediction accuracy. Furthermore, porosity predictions using the 24-h effective water also yielded accurate estimations of all the above mechanical properties. Finally, comparisons with the results of other studies validated the reliability of the models and their accuracy, especially the minimum expected values at a 95% confidence level, at all times lower than the experimental results.Spanish Ministry of Universities within the framework of the State Program for the Promotion of Talent and its Employability in R + D + i, State Mobility Subprogram, of the State Plan for Scientific and Technical Research and Innovation 2017–2020 [PRX21/00007]; the Spanish Ministry MCI, AEI, EU and ERDF [grant numbers PID2020-113837RB-I00; 10.13039/501100011033; FPU17/03374]; the Junta de Castilla y León (Regional Government) and ERDF [grant numbers UIC-231; BU119P17]; Youth Employment Initiative (JCyL) and ESF [grant number UBU05B_1274]; and finally, the University of Burgos [grant numbers SUCONS, Y135.GI] and the University of Padova