Observation of Weyl and Dirac fermions at smooth topological Volkov-Pankratov heterojunctions

Weyl and Dirac relativistic fermions are ubiquitous in topological matter. Their relativistic character enables high energy physics phenomena like the chiral anomaly to occur in solid state, which allows to experimentally probe and explore fundamental relativistic theories. Here we show that on smooth interfaces between a trivial and a topological material, massless Weyl and massive Dirac fermions intrinsically coexist. The emergence of the latter, known as Volkov-Pankratov states, is directly revealed by magneto-optical spectroscopy, evidencing that their energy spectrum is perfectly controlled by the smoothness of topological interface. Simultaneously, we reveal the optical absorption of the zero-energy chiral Weyl state, whose wavefunction is drastically transformed when the topological interface is smooth. Artificial engineering of the topology profile thus provides a novel textbook system to explore the rich relativistic energy spectra in condensed matter heterostructures.Comment: 21 pages 10 figure

Avoided level crossing at the magnetic field induced topological phase transition due to spin-orbital mixing

In 3D topological insulators, an effective closure of the bulk energy gap with increasing magnetic field expected at a critical point can yield a band crossing at a gapless Dirac node. Using high-field magnetooptical Landau level spectroscopy on the topological crystalline insulator Pb1-xSnxSe, we demonstrate that such a gap closure does not occur, and an avoided crossing is observed as the magnetic field is swept through the critical field. We attribute this anticrossing to orbital parity and spin mixing of the N=0 levels. Concurrently, we observe no gap closure at the topological phase transition versus temperature suggesting that the anticrossing is a generic property of topological phase transitions.Comment: submitte

Liquid Tissue: Proteomic Profiling of Formalin-Fixed Tissues

Identification and quantitation of candidate biomarker proteins in large numbers of individual tissues is required to validate specific proteins, or panels of proteins, for clinical use as diagnostic, prognostic, toxicological, or therapeutic markers. Mass spectrometry (MS) provides an exciting analytical methodology for this purpose. Liquid Tissue MS protein preparation allows researchers to utilize the vast, already existing, collections offormalin-fixed paraffin-embedded (FFPE) tissues for the procurement of peptides and the analysis across a variety of MS platforms

Multi-year interlaboratory exercises for the analysis of illicit drugs and metabolites in wastewater:development of a quality control system

Thirty-seven laboratories from 25 countries present the development of an inter-laboratory testing scheme for the analysis of seven illicit drug residues in standard solutions, tap- and wastewater. Almost 10 000 concentration values were evaluated: triplicates of up to five samples and 26 laboratories per year. The setup was substantially improved with experiences gained across the six repetitions (e.g. matrix type, sample conditions, spiking levels). From this, (pre-)analytical issues (e.g. pH adjustment, filtration) were revealed for specific analytes which resulted in formulation of best-practice protocols for inter-laboratory setup and analytical procedures. The results illustrate the effectiveness of the inter-laboratory setup to assess laboratory performance in the framework of wastewater-based epidemiology. The exercise proved that measurements of laboratories were of high quality (>80% satisfactory results for six out of seven analytes) and that analytical follow-up is important to assist laboratories in improving robustness of wastewater-based epidemiology results

Neural correlates of indicators of sound change in Cantonese: evidence from cortical and subcortical processes

Across time, languages undergo changes in phonetic, syntactic and semantic dimensions. Social, cognitive and cultural factors contribute to sound change, a phenomenon in which the phonetics of a language undergo changes over time. Individuals who misperceive and produce speech in a slightly divergent manner (called innovators) contribute to variability in the society, eventually leading to sound change. However, the cause of variability in these individuals is still unknown. In this study, we examined whether such misperceptions are represented in neural processes of the auditory system. We investigated behavioral, subcortical (via FFR), and cortical (via P300) manifestations of sound change processing in Cantonese, a Chinese language in which several lexical tones are merging. Across the merging categories, we observed a similar gradation of speech perception abilities in both behavior and the brain (subcortical and cortical processes). Further, we also found that behavioral evidence of tone merging correlated with subjects’ encoding at the subcortical and cortical levels. These findings indicate that tone-merger categories, that are indicators of sound change in Cantonese, are represented neurophysiologically with high fidelity. Using our results, we speculate that innovators encode speech in a slightly deviant neurophysiological manner, and thus produce speech divergently that eventually spreads across the community and contributes to sound change