17 research outputs found
Facilitating Innovation in College Environments: The Innov8 Academy
In general, faculty technology adoption lags behind administration, research, and learning support. The Innov8 Academy was developed at Polk State College to increase faculty confidence and utilization in effectively integrating technology into instruction using the action research process. Innov8 Academy sought to build formal institutional support mechanisms that would encourage self-growth and the widespread implementation of technologies that would impact student learning and success. Program participants attended an intensive four-day summer institute and monthly community of practice sessions. At the conclusion of each cohort, participants shared their findings through a poster session with the entire academic community. Currently, three cohorts completed Innov8 Academy with the fourth cohort in progress. This session will share the implementation process and supporting strategies used to develop the culture of innovation
Praying Grounds: African American Faith Communities
More than a century after the publication of The Souls of Black Folk...the church remains at the center of African American social life. However, like other aspects of social history, much of the history of religious institutions is “disappearing beneath our feet,” because not enough is being done to collect and preserve the primary evidence of the work of the church and to make this archival information available to established and budding 21st-century scholars. Praying Grounds: African American Faith Communities promises to help address this problem through the collection and preservation of archival material related to the history of these institutions in Greater Cleveland... — Dr. Regennia N. Williamshttps://engagedscholarship.csuohio.edu/cmpex/1020/thumbnail.jp
Praying Grounds: African American Faith Communities
More than a century after the publication of The Souls of Black Folk...the church remains at the center of African American social life. However, like other aspects of social history, much of the history of religious institutions is “disappearing beneath our feet,” because not enough is being done to collect and preserve the primary evidence of the work of the church and to make this archival information available to established and budding 21st-century scholars. Praying Grounds: African American Faith Communities promises to help address this problem through the collection and preservation of archival material related to the history of these institutions in Greater Cleveland... — Dr. Regennia N. Williamshttps://engagedscholarship.csuohio.edu/cmpex/1020/thumbnail.jp
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Distinct genetic influences on cortical surface area and cortical thickness.
Neuroimaging studies examining the effects of aging and neuropsychiatric disorders on the cerebral cortex have largely been based on measures of cortical volume. Given that cortical volume is a product of thickness and surface area, it is plausible that measures of volume capture at least 2 distinct sets of genetic influences. The present study aims to examine the genetic relationships between measures of cortical surface area and thickness. Participants were men in the Vietnam Era Twin Study of Aging (110 monozygotic pairs and 92 dizygotic pairs). Mean age was 55.8 years (range: 51-59). Bivariate twin analyses were utilized in order to estimate the heritability of cortical surface area and thickness, as well as their degree of genetic overlap. Total cortical surface area and average cortical thickness were both highly heritable (0.89 and 0.81, respectively) but were essentially unrelated genetically (genetic correlation = 0.08). This pattern was similar at the lobar and regional levels of analysis. These results demonstrate that cortical volume measures combine at least 2 distinct sources of genetic influences. We conclude that using volume in a genetically informative study, or as an endophenotype for a disorder, may confound the underlying genetic architecture of brain structure
Distinct Genetic Influences on Cortical Surface Area and Cortical Thickness
Neuroimaging studies examining the effects of aging and neuropsychiatric disorders on the cerebral cortex have largely been based on measures of cortical volume. Given that cortical volume is a product of thickness and surface area, it is plausible that measures of volume capture at least 2 distinct sets of genetic influences. The present study aims to examine the genetic relationships between measures of cortical surface area and thickness. Participants were men in the Vietnam Era Twin Study of Aging (110 monozygotic pairs and 92 dizygotic pairs). Mean age was 55.8 years (range: 51–59). Bivariate twin analyses were utilized in order to estimate the heritability of cortical surface area and thickness, as well as their degree of genetic overlap. Total cortical surface area and average cortical thickness were both highly heritable (0.89 and 0.81, respectively) but were essentially unrelated genetically (genetic correlation = 0.08). This pattern was similar at the lobar and regional levels of analysis. These results demonstrate that cortical volume measures combine at least 2 distinct sources of genetic influences. We conclude that using volume in a genetically informative study, or as an endophenotype for a disorder, may confound the underlying genetic architecture of brain structure
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Salivary cortisol and prefrontal cortical thickness in middle-aged men: A twin study.
Although glucocorticoid receptors are highly expressed in the prefrontal cortex, the hippocampus remains the predominant focus in the literature examining relationships between cortisol and brain. We examined phenotypic and genetic associations of cortisol levels with the thickness of prefrontal and anterior cingulate cortex regions, and with hippocampal volume in a sample of 388 middle-aged male twins who were 51-59 years old. Small but significant negative phenotypic associations were found between cortisol levels and the thickness of left dorsolateral (superior frontal gyrus, left rostral middle frontal gyrus) and ventrolateral (pars opercularis, pars triangularis, pars orbitalis) prefrontal regions, and right dorsolateral (superior frontal gyrus) and medial orbital frontal cortex. Most of the associations remained significant after adjusting for general cognitive ability, cardiovascular risk factors, and depression. Bivariate genetic analyses suggested that some of the associations were primarily accounted for by shared genetic influences; that is, some of the genes that tend to result in increased cortisol levels also tend to result in reduced prefrontal cortical thickness. Aging has been associated with reduced efficiency of hypothalamic-pituitary-adrenal function, frontal lobe shrinkage, and increases in health problems, but our present data do not allow us to determine the direction of effects. Moreover, the degree or the direction of the observed associations and the extent of their shared genetic underpinnings may well change as these individuals age. Longitudinal assessments are underway to elucidate the direction of the associations and the genetic underpinnings of longitudinal phenotypes for changes in cortisol and brain morphology
Salivary cortisol and prefrontal cortical thickness in middle-aged men: A twin study.
Although glucocorticoid receptors are highly expressed in the prefrontal cortex, the hippocampus remains the predominant focus in the literature examining relationships between cortisol and brain. We examined phenotypic and genetic associations of cortisol levels with the thickness of prefrontal and anterior cingulate cortex regions, and with hippocampal volume in a sample of 388 middle-aged male twins who were 51-59 years old. Small but significant negative phenotypic associations were found between cortisol levels and the thickness of left dorsolateral (superior frontal gyrus, left rostral middle frontal gyrus) and ventrolateral (pars opercularis, pars triangularis, pars orbitalis) prefrontal regions, and right dorsolateral (superior frontal gyrus) and medial orbital frontal cortex. Most of the associations remained significant after adjusting for general cognitive ability, cardiovascular risk factors, and depression. Bivariate genetic analyses suggested that some of the associations were primarily accounted for by shared genetic influences; that is, some of the genes that tend to result in increased cortisol levels also tend to result in reduced prefrontal cortical thickness. Aging has been associated with reduced efficiency of hypothalamic-pituitary-adrenal function, frontal lobe shrinkage, and increases in health problems, but our present data do not allow us to determine the direction of effects. Moreover, the degree or the direction of the observed associations and the extent of their shared genetic underpinnings may well change as these individuals age. Longitudinal assessments are underway to elucidate the direction of the associations and the genetic underpinnings of longitudinal phenotypes for changes in cortisol and brain morphology