1,735 research outputs found

    Denying What Workers Believe Are Unethical Workplace Requests: Do Workers Use Moral, Operational, or Policy Justifications Publicly?

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    This message-production experiment demonstrates workers’ tendency to use organizational policy justifications when publicly denying what they privately believe are unethical requests. Working adults (N = 234) responded to an unethical request from a supervisor, coworker, or subordinate. Participants avoided using explicitly moralized justifications for their noncompliance publicly and thus engaged in issue crafting. Specifically, content and statistical analyses revealed that (a) most participants invoked policy justifications to deny requests and (b) differences in hierarchical relationships were not significantly associated with policy justification frequency. These dynamics afford important face-saving functions but hold implications for the moral learning capacity of organizations. The essay concludes with implications for crafting organizational ethics policy.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

    The good, the bad and the implicit: a comprehensive approach to annotating explicit and implicit sentiment

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    We present a fine-grained scheme for the annotation of polar sentiment in text, that accounts for explicit sentiment (so-called private states), as well as implicit expressions of sentiment (polar facts). Polar expressions are annotated below sentence level and classified according to their subjectivity status. Additionally, they are linked to one or more targets with a specific polar orientation and intensity. Other components of the annotation scheme include source attribution and the identification and classification of expressions that modify polarity. In previous research, little attention has been given to implicit sentiment, which represents a substantial amount of the polar expressions encountered in our data. An English and Dutch corpus of financial newswire, consisting of over 45,000 words each, was annotated using our scheme. A subset of this corpus was used to conduct an inter-annotator agreement study, which demonstrated that the proposed scheme can be used to reliably annotate explicit and implicit sentiment in real-world textual data, making the created corpora a useful resource for sentiment analysis

    Clients’ experiences of the Boston Psychiatric Rehabilitation Approach: A qualitative study

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    The Boston Psychiatric Rehabilitation Approach (BPR) is person-centered and characterized by being based entirely on the individual's unique needs and preferences in the areas of working, learning, social contacts, and living environment. Nevertheless, the person-centered approach is lacking firm evidence regarding outcomes, and empirical studies regarding clients’ experiences of this particular model are needed. A qualitative content analysis of 10 transcribed semistructured individual interviews was used to describe and explore clients’ experiences of the BPR during an implementation project in Sweden. The findings from the interviews could be summarized in “A sense of being in communion with self and others” theme, consisting of three categories: increased self-understanding, getting new perspectives, and being in a trusting relationship. The results showed that clients do not always recognize nor are able to verbalize their goals before they have been given the possibility to reflect their thoughts in collaboration with a trusted person. The guidelines of the approach are intended to support the clients’ ability to participate in decision making regarding their own care. More research about efficacy of different rehabilitation approaches and exploration of fidelity to guidelines of rehabilitation programs are required

    Post-Disaster Housing Reconstruction in Sri Lanka: What Methodology?

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    Research methodology is the procedural framework within which the research is conducted. This includes the overall approach to a problem that could be put into practice in a research process, from the theoretical underpinning to the collection and analysis of data. Choice of methodology depends on the primary drivers: topic to be researched and the specific research questions. Hence, methodological perspectives of managing stakeholder expectations of PDHR context are composed of research philosophies, research strategy, research design, and research techniques. This research belonged to social constructivism or interpretivism within a philosophical continuum. The nature of the study was more toward subjectivism where human behavior favored voluntary stance. Ontological, methodological, epistemological, and axiological positioning carried the characteristics of idealism, ideographic, anti-positivism, and value laden, respectively. Data collection comprises two phases, preliminary and secondary. Exploratory interviews with construction experts in the United Kingdom and Sri Lanka were carried out to refine the interview questions and identify the case studies. Case study interviews during the secondary phase took place in Sri Lanka. Data collected at the preliminary stage were used to assess the attributes of power, legitimacy/proximity, and urgency of stakeholders to the project using Stakeholder Circle™ software. Moreover, the data collected at secondary phase via case studies will be analyzed with NVivo 8. This article aims to discuss these methodological underpinnings in detail applied in a post-disaster housing reconstruction context in Sri Lanka

    Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer.

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    Capecitabine (CAP) is a 5-FU pro-drug approved for the treatment of several cancers and it is used in combination with gemcitabine (GEM) in the treatment of patients with pancreatic adenocarcinoma (PDAC). However, limited pre-clinical data of the effects of CAP in PDAC are available to support the use of the GEMCAP combination in clinic. Therefore, we investigated the pharmacokinetics and the efficacy of CAP as a single agent first and then in combination with GEM to assess the utility of the GEMCAP therapy in clinic. Using a model of spontaneous PDAC occurring in Kras(G12D); p53(R172H); Pdx1-Cre (KPC) mice and subcutaneous allografts of a KPC PDAC-derived cell line (K8484), we showed that CAP achieved tumour concentrations (∼25 µM) of 5-FU in both models, as a single agent, and induced survival similar to GEM in KPC mice, suggesting similar efficacy. In vitro studies performed in K8484 cells as well as in human pancreatic cell lines showed an additive effect of the GEMCAP combination however, it increased toxicity in vivo and no benefit of a tolerable GEMCAP combination was identified in the allograft model when compared to GEM alone. Our work provides pre-clinical evidence of 5-FU delivery to tumours and anti-tumour efficacy following oral CAP administration that was similar to effects of GEM. Nevertheless, the GEMCAP combination does not improve the therapeutic index compared to GEM alone. These data suggest that CAP could be considered as an alternative to GEM in future, rationally designed, combination treatment strategies for advanced pancreatic cancer
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