11 research outputs found
Determination of the illicit drug gamma-hydroxybutyrate (GHB) in human saliva and beverages by 1
GHB measurement by GC-MS in blood, urine and gastric contents, following an acute intoxication in Belgium
Determination of Gamma-Hydroxybutyrate (GHB) and Gamma-Butyrolactone (GBL) by HPLC/UV-VIS Spectrophotometry and HPLC/Thermospray Mass Spectrometry
Determination of amphetamine and methamphetamine in umbilical cord using liquid chromatography–tandem mass spectrometry
Fast determination of cocaine and some common adulterants in seized cocaine samples by capillary electrophoresis with capacitively coupled contactless conductivity detection
GHB Free Acid: I. Solution Formation Studies and Spectroscopic Characterization by 1HNMR and FT-IR
Product ion mass spectra of amphetamine-type substances, designer analogues, and ketamine using ultra-performance liquid chromatography/tandem mass spectrometry
This paper describes the application of ultra-performance liquid chromatography/tandem mass spectrometry (UPLC/MS/MS) technology to separate and identify amphetamine-type substances (amphetamine, methamphetamine), common and novel designer analogues (MDA, MDMA, PMA,4-MTA,MBDB), and ketamine using Acquity UPLC/Micromass Quattro Micro API mass spectrometer instrumentation (Waters Corporation, USA). From injection of drug reference standards, it was demonstrated that these compounds can be identified by product ion mass spectra in less than 4 min total analysis time, indicating that the technological advancements associated with UPLC/MS/MS allow it to serve as a powerful analytical tool for high-throughput testing. In addition to demonstrating the separation and response of these drug compounds under the stated UPLC/MS/MS conditions, we believe the acquired product ion spectra will be a beneficial reference to laboratories interested in incorporating the use of this technology in the routine analysis of drugs of abuse