959 research outputs found

    Electronic Social Networks as Supporting Means of Educational Process in Higher Education Institutions

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    Given research describes experience of electronic social networks use in educational practices. It was determined that electronic social networks can be a powerful tool for support of educational process in higher education institutions, namely to support study of different disciplines. There are main advantages of electronic social networks use for education: universal accessibility and free of charge; possibility of instant messaging and multimedia data; user-friendly intuitive interface; ability to search data and information; availability of event scheduling, invitations, reminder settings; support for synchronous and asynchronous communication between network members; access from different devices. It is emphasized that one of the main advantages of electronic social networks is receipt of quick feedback and convenience of their tools and services. Nowadays, it is important to include network educational interaction in existing models of study organization. It is advisable to use electronic social networks to manage educational process in higher education institution. Efficiency of electronic social networks use depends on intensity and need for their use in educational system management for implementation of organizational, educational, psychological and pedagogical functions and ensuring universal communication with subjects of educational process. Expediency of electronic social networks use to carry out research work at university is described. Electronic social networks are convenient tool to conduct surveys and questionnaires, to create thematic groups for specific issue discussion. Also it is possible to interact with researchers from different countries, share experiences and disseminate research findings, invite those who wish to participate in various scientific activities using these networks

    Antioxidant system of oral cavity in children with inflammatory diseases oral mucosa and acute forms of leukemia under the treatment

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    Kovach I. V., Khotimskаy J. V. Antioxidant system of oral cavity in children with inflammatory diseases oral mucosa and acute forms of leukemia under the treatment. Journal of Education, Health and Sport. 2017;7(1):387-395. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.276515http://ojs.ukw.edu.pl/index.php/johs/article/view/4246    The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016).754 Journal of Education, Health and Sport eISSN 2391-8306 7© The Author (s) 2017;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 02.01.2017. Revised 16.01.2017. Accepted: 24.01.2017. ANTIOXIDANT SYSTEM OF ORAL CAVITY IN CHILDREN WITH INFLAMMATORY DISEASES ORAL MUCOSA AND ACUTE FORMS OF LEUKEMIA UNDER THE TREATMENT I. V. Kovach, J. V. Khotimskаy State Enterprise «Dnepropetrovsk Medical Academy under Ukrainian Ministry of Health»[email protected] Summary The children with inflammatory diseases of the oral mucosa on the background of acute leukemia develop antioxidant system pronounced changes, e.g. the level of its enzymatic and non-enzymatic components reduces. This increases oxidative homeostasis disorders and decreases catalase’s activity. We have developed  treatment-and-prophylactic complex containing quercetin mucosal gel and gel with a large number of polyphenols, flavonols, anthocyanins and catechins ("Vinaceous"), and dentilave "Lysomucoid", mixture of sanguinarine alkaloids disulfate and chelerythrine, anti-fungal and probiotic preparations. This complex has a pronounced stimulatory effect on the state of the antioxidant system, which largely determines the general condition of organs and tissues of the oral cavity. At the same time the developed therapeutic and preventive complex provides a consistently high level of functional activity of the antioxidant system in children with inflammatory diseases of the oral mucosa on the background of acute forms of leukemia in a year after treatment. The objective: to determine the activity of catalase in children with inflammatory diseases of the oral mucosa on the background of the acute form of leukemia in the dynamics of treatment. Materials and methods. 126 children aged 2-18 y.o. with acute lymphoblastic leukemia have been examined. All the children underwent clinical trials and then basic group and group of comparison was formed. In both groups the plaques were removed, full mouth debridement was made and systematically healthful procedures were done. Oral cavity hygiene was performed with the use of alcohol-free anti-inflammatory dentilave "Lysomucoid". The main group children additionally to oral hygiene used the developed therapeutic and prophylactic complexes. Results and Conclusions. The application of the developed therapeutic and prophylactic complexes, professional oral cavity hygiene and subsequent treatment applications had a pronounced  stimulating effect at the state of the antioxidant system, which depends greatly on the state of periodontal tissues and oral mucosa. The therapeutical method worked out provides high level of functional activity of the antioxidant system in all groups. This is especially important for acute leukemia children.Key words: leukemia, children, oral mucosa, antioxidant system, catalase

    Environmental Protection on the Example of Agricultural Lands

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    Agricultural land is the most valuable resource of today because the issue of food security in the world community now comes first. Unfortunately, the ecological condition of lands suitable for agricultural use in Ukraine and the situation in the field of their use is constantly deteriorating. The quality of land resources is declining and approaching catastrophic levels. In this regard, the purpose of the study is to explore the main aspects of legal and environmental regulation of fertile land protection and to suggest ways to improve the protection and preservation of agricultural land. The main research method is the method of analysis, thanks to which the world experience in the field of environmental protection in general and the protection of agricultural lands was comprehensively analysed. The normative-legal acts of Ukraine, which regulate the issues of land use, as well as protection and preservation of agricultural lands, were analysed. The proposed mechanisms of environmental protection on the example of agricultural lands can be used to form targeted government programs

    DEVELOPMENT OF MATHEMATICAL MEANS FOR ESTIMATION OF ECOLOGICAL AND ECONOMICAL LOSSES FROM POLLUTION OF ATMOSPHERIC AIR IN ZONES OF TECHNOGENIC OBJECTS IMPACT

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    The article describes the solution of one of the most important problems of rational use of natural resources. Modern mathematical tools for damage estimation, which are caused by atmospheric pollution to natural objects, and also methods for calculation of the cost for their renewal were developed. The solution of problem was divided into 3 stages. At the first stage it was defined basic anthropogenic sources of pollution, was illustrated conceptual behavior of pollutants in the atmosphere emitted by technological stationary point source. Choice of mathematical model that allows to determine the distribution of pollutants concentration in the air in zones of pollution by point stationary sources in the short-term discharges was proved. At the second stage it was developed mathematical tools to determine the level of objects damage, which were in the zone of pollution, depending on the intensity and duration of exposure of technogenic sources. At the third stage it was developed mathematical models to determine the recoverable amount of natural objects depending on their level of damage. Model example of developed means usage was described. Advantages of developed means over existed analogs were noticed

    Influence of tricalcium silicate on course of traumatic pulpitis

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    The use of Tricalcium Silicate (TS) as an odontotropic preparation makes it possible to create a hermetic crown restoration with a high degree of adhesion. However, the use of TS silicate by direct pulp capping remains disputable. The aim of this study was to determine the effects of TS on course of traumatic pulpitis by detection of morpho-functional peculiarities of changes in pulp tissue. We performed experimental investigation (on rabbits, males, aging three-month) for study of the morphofunctional changes of the pulp tissues with modeling of traumatic pulpitis and direct pulp capping with TS preparation (8 animals, investigated group) and calcium hydroxide (Calasept, NORDISKA DENTAL) preparation (8 animals, comparison group). After 2nd and 6th weeks tissues of tooth were fixed in 10% formalin with performing routine proceeding after decalcification and making histological slides which were investigated. Manifestations of protective adaptive mechanisms have been revealed in the form of inflammatory process two weeks after the injury in the pulp tissue with its resolution six weeks after performing of direct pulp capping with TS with replacement of necrotic area by connective tissue with their delimitation from viable pulp tissue against a background of intensive formation of capillaries. Morphometric study proved dynamical changes of vascular number cross-sections per 1 mm2 from 69.31±4.76 (2 weeks) to 47.38±4.12 (6 weeks) with 49.2±3.47 vascular density in intact group. Cellular density of odontoblasts as changed from 3.92±1.03 x103 per 1 mm2 (2 weeks) to 7.49±1.51 x103 per 1 mm2 (6 weeks) with 8.3±1.02 x103 per 1 mm2 cellular density in intact group. Thus it can be argued that the use of TS as a material for direct pulp capping promotes more active regeneration processes. Целью исследования явилось определение влияния трикальцийсиликата на течение травматического пульпита. Поставлен эксперимент на 3-месячных кроликахсамцах для изучения морфофункциональных изменений ткани пульпы с моделированием травматического пульпита и прямым покрытием пульпы трикальцийсиликатом (8 животных, исследуемая группа) и гидроксидом кальция (Calasept, NORDISKA DENTAL) (8 животных, группа сравнения). Спустя 2 и 6 недели ткани зуба фиксировали в 10% формалине и после декальцификации и рутинной проводки исследовали гистологические препараты. Спустя 2 недели после нанесения травмы в ткани пульпы обнаружены проявления защитно-приспособительных механизмов в виде воспалительного процесса с его разрешением, при котором наблюдается замещение зоны некроза соединительной тканью на фоне интенсивного новообразования капилляров, что характеризуется изменением плотности сосудов микроциркуляторного русла. Морфометрическое исследование показало динамические изменения количества сосудистых сечений с 69,31±4,76/мм2 (2 недели) до 47,38±4,12/мм2 (6 недель) при 49,2±3,47/мм2 в интактной группе. Плотность одонтобластов изменилась с 3,92±1,03×103/мм2 (2 недели) до 7,49±1,51×103/мм2 (6 недель) при 8,3±1,02×103/мм2 клеточной плотности в интактной группе. Таким образом, следует предположить, что использование трикальцийсиликата в качестве материала для прямого покрытия пульпы способствует более активным процессам регенерации

    Захист прав і основоположних свобод людини в межах Ради Європи

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    У статті автор розглядає проблему захисту прав і основоположних свобод в межах Ради Європи. Автор посилається на відповідні нормативно-правові акти, що регулюють дане питання й обґрунтовує необхідність врегулювання проблеми захисту прав і основоположних свобод

    Dynamics of findings of non-specific resistance in the mouth cavity in children with lesions of the mucous membrane epithelium of the mouth cavity against acute lymphoblastic leukemia in the treatment process.

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    There was con­ducted study of dynamics of findings of non-specific resistance in the mouth cavity in children with lesions of the mucous membrane epithelium of the mouth cavity against acute lymphoblastic leukemia  in the treatment process by authors-developed methods. It is known that in children with leukemia immunodeficiency states develop immunological disorders resulted from treatment with cytotoxic drugs. Moreover, not only general, but also the local immunity of the mouth cavity suffers, which is accompanied by development of infectious processes in the tissues that perform the barrier function, which include mucous membrane epithelium of the mouth cavity. A key role in the system of antimicrobial protection of the mouth cavity is performed by mucolytic enzyme lisocyme and α-defensins (HNP 1-3). 76 children with acute lymphoblastic leukemia  aged from 2 to 18 years suffering  from such dental diseases as generalized chronic catarrhal gingivitis, erosive-ulcerative and candidal stomatitis took part in the clinical study. All children under clinical study were divided into 2 groups - the main and comparison. Standard protocol treatment was used in the comparison group. Developed treatment-and-prophylactic complex was used in the main group. The children of the main group were prescribed developed treatment-and-prophylactic complex depending on the period of the disease: the first version of local treatment was used in the acute period and the relapse of the disease, the second - in the period of remission. The results of research have shown a stimulating effect of therapeutic and prophylactic measures on the natural antimicrobial system of mouth cavity protection, both in children of the main groups under study and in the comparison groups. Such a phenomenon should be considered as a positive process that contributes to the increase of resistance in periodontal tissues and mucous membrane epithelium of the mouth cavity
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