Adaptive neural reward processing during anticipation and receipt of monetary rewards in mindfulness meditators

Reward seeking is ubiquitous and adaptive in humans. But excessive reward seeking behavior, such as chasing monetary rewards, may lead to diminished subjective well-being. This study examined whether individuals trained in mindfulness meditation show neural evidence of lower susceptibility to monetary rewards. Seventy-eight participants (34 meditators, 44 matched controls) completed the monetary incentive delay task while undergoing functional magnetic resonance imaging. The groups performed equally on the task, but meditators showed lower neural activations in the caudate nucleus during reward anticipation, and elevated bilateral posterior insula activation during reward anticipation. Meditators also evidenced reduced activations in the ventromedial prefrontal cortex during reward receipt compared with controls. Connectivity parameters between the right caudate and bilateral anterior insula were attenuated in meditators during incentive anticipation. In summary, brain regions involved in reward processingboth during reward anticipation and receipt of rewardresponded differently in mindfulness meditators than in nonmeditators, indicating that the former are less susceptible to monetary incentives

Cognitive framing modulates emotional processing through dorsolateral prefrontal cortex and ventrolateral prefrontal cortex networks: A functional magnetic resonance imaging study

Introduction: In this study, we show new evidence for the role of ventrolateral prefrontal cortex-dorsolateral prefrontal cortex (VLPFC-DLPFC) networks in the cognitive framing of emotional processing. Method: We displayed neutral and aversive images described as having been sourced from artistic material to one cohort of subjects (i.e., the art-frame group; n = 19), while identical images, this time identified as having been sourced from documentary material (i.e., the doc-frame group; n = 20) were shown to a separate cohort. Results: Using functional magnetic resonance imaging (fMRI), we employed a linear parametric model showing that relative to the doc-frame group the art-frame group exhibited a modulation of amygdala activity in response to aversive images. The attenuated amygdala activity in the art-frame group supported our hypothesis that reduced amygdala activity was driven by top-down DLPFC inhibition of limbic responses. A psychophysiological interaction (PPI) analysis demonstrated that VLPFC activity correlated with amygdala activity in the art-frame group, but not in the docframe group for the contrast [Aversive > Neutral]. Conclusion: The role of the VLPFC in cognitive control suggests the hypothesis that it alongside DLPFC insulates against embodied emotional responses by inhibiting automatic affective responses

Progress in understanding Blazars from BeppoSAX observations

Results obtained with BeppoSAX observations of blazars within various collaborative programs are presented. The spectral similarity "paradigm", whereby the spectral energy distributions of blazars follow a sequence, leading to a unified view of the whole population, is briefly illustrated. We concentrate on recent observations of flares and associated spectral variability for three objects at the "blue" end of the spectral sequence, namely PKS 2155-304, Mkn 421 and Mkn 501. The results are discussed in terms of a general analytic synchrotron self-Compton interpretation of the overall spectrum. The physical parameters of the quasi-stationary emission region can be derived with some confidence, while the variability mechanism(s) must be complex.Comment: 10 pages, 8 figures, to be published in the Proceedings of the 32nd COSPAR Meeting, Nagoya, 12-19 July 199

Observing the gas temperature drop in the high-density nucleus of L 1544

Abridged: The thermal structure of a starless core is crucial for our understanding of the physics in these objects and hence for our understanding of star formation. Theory predicts a gas temperature drop in the inner 5000 AU of these objects, but there has been little observational proof of this. We performed VLA observations of the NH3 (1,1) and (2,2) transitions towards the pre-stellar core L 1544 in order to measure the temperature gradient between the high density core nucleus and the surrounding core envelope. Our VLA observation for the first time provide measurements of gas temperature in a core with a resolution smaller than 1000 AU. We have also obtained high resolution Plateau de Bure observations of the 110 GHz 111-101 para-NH2D line in order to further constrain the physical parameters of the high density nucleus. We have estimated the temperature gradient using a model of the source to fit our data in the u,v plane. We find that indeed the temperature decreases toward the core nucleus from 12 K down to 5.5 K resulting in an increase of a factor of 50% in the estimated density of the core from the dust continuum if compared with the estimates done with constant temperature of 8.75 K. We also found a remarkably high abundance of deuterated ammonia with respect to the ammonia abundance (50%+-20%), which proves the persistence of nitrogen bearing molecules at very high densities (2e6 cm-3) and shows that high-resolution observations yield higher deuteration values than single-dish observations. Our analysis of the NH3 and NH2D kinematic fields shows a decrease of specific angular momentum from the large scales to the small scales.Comment: 12 pages, 6 figures. Accepted for publication by A&

Synchrotron and inverse-Compton emission from blazar jets I: a uniform conical jet model

In the first of a series of papers investigating emission from blazar jets from radio to high-energy {\gamma}-rays, we revisit the class of models where the jet has a uniform conical ballistic structure. We argue that by using simple developments of these models, in the context of new multi-frequency data extending to gamma-ray energies, valuable insights may be obtained into the properties that fully realistic models must ultimately have. In this paper we consider the synchrotron and synchrotron-self-Compton emission from the jet, modelling the recent simultaneous multi-wavelength observations of BL Lac. This is the first time these components have been fitted simultaneously for a blazar using a conical jet model. In the model we evolve the electron population dynamically along the jet taking into account the synchrotron and inverse-Compton losses. The inverse-Compton emission is calculated using the Klein-Nishina cross section and a relativistic transformation into the jet frame, and we explicitly show the seed photon population. We integrate synchrotron opacity along the line of sight through the jet plasma, taking into account the emission and opacity of each section of the jet. In agreement with previous studies of radio emission, we find that a conical jet model which conserves magnetic energy produces the characteristic blazar flat radio spectrum, however, we do not require any fine-tuning of the model to achieve this. Of particular note, in our model fit to BL Lac--which at ~10^37W is a relatively low jet-power source--we find no requirement for significant re-acceleration within the jet to explain the observed spectrum.Comment: 11 pages, 6 figures, accepted for publication in MNRA

Tetraphenyl­arsonium cis-bis­[1,2-bis­(tri­fluoro­meth­yl)ethene-1,2-dithiol­ato]platinate(II)

In the title compound, (C24H20As)[Pt(C4F6S2)2], the cation lies on a twofold rotation axis while the anion has crystallographic inversion symmetry. The PtII ion is in a slightly distorted square-planar coordination environment. The F atoms of both unique –CF3 groups are disordered over two sets of sites, the ratios of refined occupancies being 0.677 (15):0.323 (15) and 0.640 (16):0.360 (16). The crystal structure is the first to date of a monoanionic [Pt(tfd)2]− species [tfd is 1,2-bis­(trifluoro­meth­yl)ethene-1,2-dithiol­ate] with a non-redox-active cation

Research and Education in Computational Science and Engineering

Over the past two decades the field of computational science and engineering (CSE) has penetrated both basic and applied research in academia, industry, and laboratories to advance discovery, optimize systems, support decision-makers, and educate the scientific and engineering workforce. Informed by centuries of theory and experiment, CSE performs computational experiments to answer questions that neither theory nor experiment alone is equipped to answer. CSE provides scientists and engineers of all persuasions with algorithmic inventions and software systems that transcend disciplines and scales. Carried on a wave of digital technology, CSE brings the power of parallelism to bear on troves of data. Mathematics-based advanced computing has become a prevalent means of discovery and innovation in essentially all areas of science, engineering, technology, and society; and the CSE community is at the core of this transformation. However, a combination of disruptive developments---including the architectural complexity of extreme-scale computing, the data revolution that engulfs the planet, and the specialization required to follow the applications to new frontiers---is redefining the scope and reach of the CSE endeavor. This report describes the rapid expansion of CSE and the challenges to sustaining its bold advances. The report also presents strategies and directions for CSE research and education for the next decade.Comment: Major revision, to appear in SIAM Revie

Clastic Polygonal Networks Around Lyot Crater, Mars: Possible Formation Mechanisms From Morphometric Analysis

Polygonal networks of patterned ground are a common feature in cold-climate environments. They can form through the thermal contraction of ice-cemented sediment (i.e. formed from fractures), or the freezing and thawing of ground ice (i.e. formed by patterns of clasts, or ground deformation). The characteristics of these landforms provide information about environmental conditions. Analogous polygonal forms have been observed on Mars leading to inferences about environmental conditions. We have identified clastic polygonal features located around Lyot crater, Mars (50°N, 30°E). These polygons are unusually large (> 100 m diameter) compared to terrestrial clastic polygons, and contain very large clasts, some of which are up to 15 metres in diameter. The polygons are distributed in a wide arc around the eastern side of Lyot crater, at a consistent distance from the crater rim. Using high-resolution imaging data, we digitised these features to extract morphological information. These data are compared to existing terrestrial and Martian polygon data to look for similarities and differences and to inform hypotheses concerning possible formation mechanisms. Our results show the clastic polygons do not have any morphometric features that indicate they are similar to terrestrial sorted, clastic polygons formed by freeze-thaw processes. They are too large, do not show the expected variation in form with slope, and have clasts that do not scale in size with polygon diameter. However, the clastic networks are similar in network morphology to thermal contraction cracks, and there is a potential direct Martian analogue in a sub-type of thermal contraction polygons located in Utopia Planitia. Based upon our observations, we reject the hypothesis that polygons located around Lyot formed as freeze-thaw polygons and instead an alternative mechanism is put forward: they result from the infilling of earlier thermal contraction cracks by wind-blown material, which then became compressed and/or cemented resulting in a resistant fill. Erosion then leads to preservation of these polygons in positive relief, while later weathering results in the fracturing of the fill material to form angular clasts. These results suggest that there was an extensive area of ice-rich terrain, the extent of which is linked to ejecta from Lyot crater