An ultraluminous supersoft source with a 4 hour modulation in NGC 4631

Context. Supersoft X-ray sources (SSSs) are characterised by very low temperatures (< 100 eV). Classical SSSs have bolometric luminosities in the range of 10^36-10^38 erg/s and are modelled with steady nuclear burning of hydrogen on the surfaces of white dwarfs. However, several SSSs have been discovered with much higher luminosities. Their nature is still unclear. Aims. We report the discovery of a 4h modulation for an ultraluminous SSS in the nearby edge-on spiral galaxy NGC 4631, observed with XMM-Newton in 2002 June. Temporal and spectral analysis of the source is performed. Methods. We use a Lomb-Scargle periodogram analysis for the period search and evaluate the confidence level using Monte-Carlo simulations. We measure the source temperature, flux and luminosity through spectral fitting. Results. A modulation of 4.2+-0.4 h (3 sigma error) was found for the SSS with a confidence level >99%. Besides dips observed in the light curve, the flux decreased by a factor of 3 within ~10h. The spectrum can be described with an absorbed blackbody model with kT~67eV. The absorbed luminosity in the 0.2-2 kev energy band was 2.7x10^38 erg/sec while the bolometric luminosity was a hundred time higher (3.2x10^40 erg/s), making the source one of the most luminous of its class, assuming the best fit model is correct. Conclusions. This source is another very luminous SSS for which the standard white dwarf interpretation cannot be applied, unless a strong beaming factor is considered. A stellar-mass black hole accreting at a super Eddington rate is a more likely interpretation, where the excess of accreted matter is ejected through a strong optically-thick outflow. The 4 h modulation could either be an eclipse from the companion star or the consequence of a warped accretion disk.Comment: 4 pages, 4 figures, accepted as a Letter in Astronomy & Astrophysic

Neutrophil gelatinase-associated lipocalin: its response to hypoxia and association with acute mountain sickness.

Acute Mountain Sickness (AMS) is a common clinical challenge at high altitude (HA). A point-of-care biochemical marker for AMS could have widespread utility. Neutrophil gelatinase-associated lipocalin (NGAL) rises in response to renal injury, inflammation and oxidative stress. We investigated whether NGAL rises with HA and if this rise was related to AMS, hypoxia or exercise. NGAL was assayed in a cohort (n = 22) undertaking 6 hours exercise at near sea-level (SL); a cohort (n = 14) during 3 hours of normobaric hypoxia (FiO2 11.6%) and on two trekking expeditions (n = 52) to over 5000 m. NGAL did not change with exercise at SL or following normobaric hypoxia. During the trekking expeditions NGAL levels (ng/ml, mean ± sd, range) rose significantly (P < 0.001) from 68 ± 14 (60-102) at 1300 m to 183 ± 107 (65-519); 143 ± 66 (60-315) and 150 ± 71 (60-357) at 3400 m, 4270 m and 5150 m respectively. At 5150 m there was a significant difference in NGAL between those with severe AMS (n = 7), mild AMS (n = 16) or no AMS (n = 23): 201 ± 34 versus 171 ± 19 versus 124 ± 12 respectively (P = 0.009 for severe versus no AMS; P = 0.026 for mild versus no AMS). In summary, NGAL rises in response to prolonged hypobaric hypoxia and demonstrates a relationship to the presence and severity of AMS

Analysis of a rapid sea ice retreat event in the Bellingshausen Sea

The winter advance of the sea ice edge in the Bellingshausen Sea is frequently interrupted by periods of rapid retreat lasting a few days. The frequency and duration of such events strongly controls the location of the late winter sea ice edge in this sector of the Antarctic. We examine the dynamics and thermodynamics of a retreat event that occurred in May 2001 using data from a drifting buoy array together with diagnostics from a kinematic/thermodynamic ice growth model and a high-resolution (11 km) regional coupled ocean-ice model. During the retreat event, the ice edge retreated by 250 km over 13 days in response to strong and persistent northerly winds associated with a quasi-stationary low-pressure system. Ice motion in the outer part of the pack was convergent and correlated strongly with local wind forcing. By contrast, in the region closer to the coast, ice motion was less well correlated with wind forcing. Model diagnostics indicate that ice thickening resulting from convergence in the outer pack was largely balanced by basal melting. In the outer pack, ice was in a state close to free drift while, closer to the coast, internal ice stresses became significant. The ocean-ice model simulated the characteristics of the retreat event realistically, giving us confidence in the ability of such models to reproduce ice conditions in this sector

A framework for automated anomaly detection in high frequency water-quality data from in situ sensors

River water-quality monitoring is increasingly conducted using automated in situ sensors, enabling timelier identification of unexpected values. However, anomalies caused by technical issues confound these data, while the volume and velocity of data prevent manual detection. We present a framework for automated anomaly detection in high-frequency water-quality data from in situ sensors, using turbidity, conductivity and river level data. After identifying end-user needs and defining anomalies, we ranked their importance and selected suitable detection methods. High priority anomalies included sudden isolated spikes and level shifts, most of which were classified correctly by regression-based methods such as autoregressive integrated moving average models. However, using other water-quality variables as covariates reduced performance due to complex relationships among variables. Classification of drift and periods of anomalously low or high variability improved when we applied replaced anomalous measurements with forecasts, but this inflated false positive rates. Feature-based methods also performed well on high priority anomalies, but were also less proficient at detecting lower priority anomalies, resulting in high false negative rates. Unlike regression-based methods, all feature-based methods produced low false positive rates, but did not and require training or optimization. Rule-based methods successfully detected impossible values and missing observations. Thus, we recommend using a combination of methods to improve anomaly detection performance, whilst minimizing false detection rates. Furthermore, our framework emphasizes the importance of communication between end-users and analysts for optimal outcomes with respect to both detection performance and end-user needs. Our framework is applicable to other types of high frequency time-series data and anomaly detection applications

A high velocity ionised outflow and XUV photosphere in the narrow emission line quasar PG1211+143

We report on the analysis of a ~60 ksec XMM observation of the bright, narrow emission line quasar PG 1211+143. Absorption lines are seen in both EPIC and RGS spectra corresponding to H- and He-like ions of Fe, S, Mg, Ne, O, N and C. The observed line energies indicate an ionised outflow velocity of ~24000 km s^-1. The highest energy lines require a column density of N_H ~ 5 x 10^23 cm^-2, at an ionisation parameter of log(xi) ~ 3.4. If the origin of this high velocity outflow lies in matter being driven from the inner disc, then the flow is likely to be optically thick within a radius ~130 Schwarzschild radii, providing a natural explanation for the Big Blue Bump (and strong soft X-ray) emission in PG 1211+143.Comment: Accepted by MNRAS; Table 1 correcte

The Identification of Genetic Synteny Between \u3ci\u3eLolium Perenne\u3c/i\u3e Chromosome 7 and Rice Chromosome 6 Genomic Regions that have Major Effects on Heading-Date

Comparative genetic mapping between plant species has established that there has been a conservation of genomic organisation which reflects evolutionary relationships. The genetic mapping of L. perenne has identified such syntenic relationships with both the Triticeae and rice. The recent publication of the complete sequence of the rice genome has allowed these relationships to be analysed more closely and has raised the possibility of using the rice genome as a template for chromosome landing-based gene identification in related non-model species. The aim of the present work was to map particular markers and genes associated with heading-date in rice in L. perenne in order to test this comparative genomics approach

A new luminous supersoft X-ray source in NGC 300

Context. We report the discovery of a new luminous supersoft source, XMMU J005455.0−374117, in the nearby spiral galaxy GC 300, in XMM-Newton observations performed on 2005 May 22 and on 2005 November 25. The source is not present in ROSAT data nor in the previous XMM-Newton observations of 2000 December/2001 January. The unique luminous supersoft source,XMMU J005510.7−373855, detected in the 1992 May/June ROSAT data and in the 2000/2001 XMM-Newton data, fell below detectability. This source already appeared highly variable in ROSAT observations. Aims. We report on the temporal and spectral analysis of this new supersoft source (SSS) and compare its properties with the previous known SSS. Methods. We present the light curves of the SSS, model its spectrum and estimate the corresponding flux and luminosities. Results. The light curve of XMMU J005455.0−374117 does not show large fluctuations in any of the observations and its spectrum can be modelled with an absorbed blackbody with kT ∼ 60 eV. The corresponding bolometric luminosity is 8.1+1.4 −4.5 × 1038 erg s−1 in the first observation and drops to 2.2+0.5 −1.4 × 1038 erg s−1 six months later. No optical source brighter than mV ∼ 21.7 mag is found coincident with its position. Conclusions. The luminosity of these two SSSs is higher than what has been found for “classical” SSSs. Their nature could be explained by beamed emission from steady nuclear burning of hydrogen onto white dwarfs, or accretion onto stellar-mass black hole with matter outflow or observed at high inclination angle. The presence of an intermediate-mass black hole seems unlikely in our case

The variable X-ray spectrum of Markarian 766 - I. Principal components analysis

Aims: We analyse a long XMM-Newton spectrum of the narrow-line Seyfert 1 galaxy Mrk 766, using the marked spectral variability on timescales >20ks to separate components in the X-ray spectrum. Methods: Principal components analysis is used to identify distinct emission components in the X-ray spectrum, possible alternative physical models for those components are then compared statistically. Results: The source spectral variability is well-explained by additive variations, with smaller extra contributions most likely arising from variable absorption. The principal varying component, eigenvector one, is found to have a steep (photon index 2.4) power-law shape, affected by a low column of ionised absorption that leads to the appearance of a soft excess. Eigenvector one varies by a factor 10 in amplitude on time-scales of days and appears to have broad ionised Fe K-alpha emission associated with it: the width of the ionised line is consistent with an origin at about 100 gravitational radii. There is also a strong component of near-constant emission that dominates in the low state, whose spectrum is extremely hard above 1 keV, with a soft excess at lower energies, and with a strong edge at Fe K but remarkably little Fe K-alpha emission. Although this component may be explained as relativistically-blurred reflection from the inner accretion disc, we suggest that its spectrum and lack of variability may alternatively be explained as either (i) ionised reflection from an extended region, possibly a disc wind, or (ii) a signature of absorption by a disc wind with a variable covering fraction. Absorption features in the low state may indicate the presence of an outflow.Comment: 14 pages, accepted for publication in Astronomy & Astrophysic

Acceptance and commitment therapy for adults with advanced cancer (CanACT): study protocol for a feasibility randomised controlled trial

BACKGROUND: One-third of people with cancer experience psychological distress and may suppress distressing thoughts, emotions, and concerns, leading to further problems. Conventional psychological treatments reduce distress by problem solving, but in advanced cancer, when ill health is progressive and death may be approaching, physical and psychological difficulties are complex and have no simple solutions. Acceptance and Commitment Therapy encourages acknowledgement and acceptance of mental experiences, increasing people's ability to work with problems that cannot be solved. Previous pilot work in advanced cancer confirms that distress can be associated with an avoidance of experiencing uncomfortable thoughts and emotions. METHODS/DESIGN: This feasibility randomised controlled trial of Acceptance Commitment Therapy aims to establish parameters for a larger trial. Fifty-four participants with advanced cancer will be randomly allocated to up to eight sessions (each 1 hour) of Acceptance Commitment Therapy or a talking control. Participants will be recruited from those attending outpatient services and hospice day care at three specialist palliative care units in North and East London, United Kingdom. The primary outcome is a measure of functioning in four areas of life (physical, social/family, emotional, and general activity) using the Functional Assessment of Cancer Therapies - General questionnaire at 3 months after randomisation. Secondary outcomes are (i) acceptance using the Acceptance and Action Questionnaire; (ii) psychological distress using the Kessler Psychological Distress Scale; (iii) physical functioning using a timed walk and sit-to-stand test; and (iv) quality of life measures including the Euroqol-5 Dimensions and ICECAP Supportive Care measures. Qualitative data will be collected at 3 months to explore the participants' experiences of the trial and therapy. Data will be collected on the costs of care. DISCUSSION: Data generated on the recruitment, retention, and experience of the interventions and the usefulness of the outcome measures will inform the adaptations required and whether changes in function are consistent with existing data when planning for a sufficiently powered randomised controlled trial. TRIAL REGISTRATION: ISRCTN13841211 (registered 22 July 2015)

An XMM-Newton view of the `bare' nucleus of Fairall 9

We present the spectral results from a 130 ks observation, obtained from the X-ray Multi-Mirror Mission-Newton (XMM-Newton) observatory, of the type I Seyfert galaxy Fairall 9. An X-ray hardness-ratio analysis of the light-curves, reveals a `softer-when-brighter' behaviour which is typical for radio-quiet type I Seyfert galaxies. Moreover, we analyse the high spectral-resolution data of the reflection grating spectrometer and we did not find any significant evidence supporting the presence of warm-absorber in the low X-ray energy part of the source's spectrum. This means that the central nucleus of Fairall 9 is `clean' and thus its X-ray spectral properties probe directly the physical conditions of the central engine. The overall X-ray spectrum in the 0.5-10 keV energy-range, derived from the EPIC data, can be modelled by a relativistically blurred disc-reflection model. This spectral model yields for Fairall 9 an intermediate black-hole best-fit spin parameter of $\alpha=0.39^{+0.48}_{-0.30}$.Comment: Accepted for publication in MNRAS. The paper contains 11 figures and 1 tabl