The early definitive internal fixation of Complex Pelvic Fracture and its outcome: our experience in level 1 trauma care centre.

Background: Complex pelvic fractures have high mortality and morbidity hence required urgent resuscitation, haemodynamic stabilization and fracture fixation. Keeping in mind the various schools of thought regarding definitive management, there is need to study the outcomes of complex pelvic fractures after internal fixation surgery.Methods: Twenty patients with complex pelvic fractures treated with internal fixation surgery in between 1st June 2018-31st December 2019 with at least 12 months follow-up were included. Clinical and functional outcome of these patients was studied and evaluated using Majeed and Hannover scoring systems.Results: Of 20 patients, 19 had closed while 1 had open pelvic fracture while 11 had tile type B and 9 had tile type C fracture. After 12 months of follow up, 72% patients of tile B fractures and 55.6% in tile C had excellent Majeed score with rest having good score. Hannover score was very good in 36.4% tile B cases and 22.2% tile C cases and good in 63.6% tile B cases and 77.8% tile C cases. Type of fracture (type B or type C) had a statistically significant co-relation with chronic pain (p=0.016). It was also found that urogenital injury and sexual dysfunction (p=0.007) had a significant co-relation.Conclusions: Early definitive internal fixation in patients with complex pelvic fracture had very good clinical and functional outcome. Most common associated injuries in complex pelvic fractures are urogenital injuries due to close proximity. In the outcomes chronic pain and sexual dysfunction are major issues. The sexual dysfunction patients usually associated fracture of pubic rami or pubic diastasis

Advanced EEG Signal Based Min to Mean Algorithm Approach For Human Emotion Taxonomy And Mental State Analysis

With electroencephalography (EEG) brain waves alone, it is full-scale phenomena in the field of computer-brain interface DNN, CNN, and SVM have improved detection and prediction accuracy in a number of researches during the last several years. But when it comes to recognizing global reliance, both deep learning and SVM have obvious limits. Pre-processing, extraction capabilities, and network design are the most common techniques used in deep learning models today, yet they are still unable to produce reliable results in noisy and sparse datasets. Any dataset, no matter how little or large, may suffer from poor SVM performance due to overlapping target instructions and boundaries. There are many different sorts of emotions that may be classified using the particular approach employed in this research. In order to get a whole picture of a person's mental state, it is best to use a "Min of mean” proposed technique. After comparison to the referential mean, a feeling is divided into one of four emotional quadrants. The MIN Max range is used to further split the emotion into 12 subcategories based on the amount of arousal. The proposed set of rules performed better than existing methods. Research on multi-class emotion reputation has shown that, compared to more recent studies, the proposed technique may be rather strong. It is possible to analyze a person's mental health by using the emotional spectrum, which has an accuracy rate of above 90%

Applications Sharing using Binding Server for Distributed Environment

Abstract Today's environment is a fast growing environment and data is distributed for the expansion of computation. Distributed computing has a major issue such as how to share a data, how to locate the services and how to make it scalable. When a limited number of nodes are available and load of running application is more as well as overhead are also major then sharing of applications among the node will definitely improve the performance of system. Locating the registered nodes to the binding server is located by making remote procedure call. Using appropriate load balancing technique threshold value will be calculated and sharing of the application on node are performed and utilization of processor as well as resources can be balanced accordingly

Proposed design for circular antenna and half ring antenna for UWB Application

In this paper, Ultra wideband planar circular patch and half circular ring patch antennas are proposed. These newly simulated structures are proposed for fabrication. The antennas are suitable for operating frequency of 7.5 GHz. It is shown that return loss of the both the antennas at 7.5 GHz is better than -10 dB. The VSWR obtained is less than 2. The half ring patch antenna is found to have the compact size and more bandwidth as that of circular patch antenna. HFSS11 is used for the simulation. From HFSS11 simulations, dimensions of antennas are chosen for better performance. Details of the proposed antenna design and measured results are presented in this pape

A randomized, placebo-controlled double-blinded comparative clinical study of five over-the-counter non-pharmacological topical analgesics for myofascial pain: single session findings

<p>Abstract</p> <p>Objectives</p> <p>To investigate the effects of topical agents for the treatment of Myofascial Pain Syndrome (MPS) and Myofascial Trigger Point (MTRP).</p> <p>Methods</p> <p>Subjects with an identifiable trigger point in the trapezius muscle, age 18-80 were recruited for a single-session randomized, placebo-blinded clinical study. Baseline measurements of trapezius muscle pressure pain threshold (PPT: by pressure algometer) along with right and left cervical lateral flexion (rangiometer) were obtained by a blinded examiner. An assessor blinded to the outcomes assessments applied one of 6 topical formulations which had been placed in identical plastic containers. Five of these topicals were proposed active formulations; the control group was given a non-active formulation (PLA). Five minutes after the application of the formula the outcome measures were re-tested. Data were analyzed with a 5-way ANOVA and Holms-adjusted t-tests with an alpha level of 0.05.</p> <p>Results</p> <p>120 subjects were entered into the study (63 females; ages 16-82); 20 subjects randomly allocated into each group. The pre- and post-treatment results for pressure threshold did show significant intra-group increases for the Ben-Gay Ultra Strength Muscle Pain Ointment (BG), the Professional Therapy MuscleCare Roll-on (PTMC roll-on) and Motion Medicine Cream (MM) with an increased threshold of 0.5 kg/cm²(+/-0.15), 0.72 kg/cm^{<b>2 </b>}(+/-0.17) and 0.47 Kg/cm^{<b>2 </b>}(+/-0.19) respectively. With respect to the inter-group comparisons, PTMC roll-on showed significant increases in pressure threshold compared with Placebo (PLA) (p = 0.002) and Icy Hot Extra Strength Cream (IH) (p = 0.006). In addition, BG demonstrated significant increases in pressure threshold compared with PLA (p = 0.0003).</p> <p>Conclusions</p> <p>With regards to pressure threshold, PTMC roll-on, BG and MM showed significant increases in pain threshold tolerance after a short-term application on a trigger points located in the trapezius muscle. PTMC roll-on and BG were both shown to be superior vs placebo while PTMC was also shown to be superior to IH in patients with trigger points located in the trapezius muscle on a single application.</p> <p>CMCC Research Ethics Board Approval # 1012X01, 2011</p

Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study

Introduction: Acne is a multifactorial and common skin disease which can significantly affect the quality of life of sufferers. In this study, a topical herbal preparation traditionally used in Ayurvedic medicine was evaluated as a treatment for individuals with acne on their shoulders and backs. Methods: Study participants were randomly assigned either to treatment (Eladi Keram) or vehicle control (coconut oil) groups under double blind conditions and instructed on its daily home application. Standardised lesion counting and acne grading were conducted in accordance with US Food and Drug Administration guidelines and with reference to the Leeds Acne Grading Technique. Participants were assessed for severity of the condition at commencement and on day 28 of treatment. Results: The treatment group showed improvements of 42% (p < 0.005) on the Investigators Global Assessment scale, a 60% (p < 0.05) reduction in inflammatory lesions, a 59% (p < 0.05) reduction in non-inflammatory lesions, and a 59% (p < 0.005) reduction in combined lesion count. The control group showed no statistically significant changes for these criteria. Conclusion: This study is the first reported clinical evaluation of Eladi Keram as a treatment for acne and findings suggest that it could be effective in reducing inflammatory and non-inflammatory lesions, warranting further investigation by means of a larger scale clinical trial

Acetyl-11-keto-β-boswellic acid (AKBA); targeting oral cavity pathogens

<p>Abstract</p> <p>Background</p> <p>Boswellic acids mixture of triterpenic acids obtained from the oleo gum resin of <it>Boswellia serrata </it>and known for its effectiveness in the treatment of chronic inflammatory disease including peritumor edema. Boswellic acids have been extensively studied for a number of activities including anti inflammatory, antitumor, immunomodulatory, and inflammatory bowel diseases. The present study describes the antimicrobial activities of boswellic acid molecules against oral cavity pathogens. Acetyl-11-keto-β-boswellic acid (AKBA), which exhibited the most potent antibacterial activity, was further evaluated in time kill studies, mutation prevention frequency, postantibiotic effect (PAE) and biofilm susceptibility assay against oral cavity pathogens.</p> <p>Findings</p> <p>AKBA exhibited an inhibitory effect on all the oral cavity pathogens tested (MIC of 2-4 μg/ml). It exhibited concentration dependent killing of S<it>treptococcus mutans </it>ATCC 25175 up to 8 × MIC and also prevented the emergence of mutants of <it>S.mutans </it>ATCC 25175 at 8× MIC. AKBA demonstrated postantibiotic effect (PAE) of 5.7 ± 0.1 h at 2 × MIC. Furthermore, AKBA inhibited the formation of biofilms generated by <it>S.mutans </it>and <it>Actinomyces viscosus </it>and also reduced the preformed biofilms by these bacteria.</p> <p>Conclusions</p> <p>AKBA can be useful compound for the development of antibacterial agent against oral pathogens and it has great potential for use in mouthwash for preventing and treating oral infections.</p

Evidence of effectiveness of herbal medicinal products in the treatment of arthritis

Herbal medicinal products (HMPs) that interact with the mediators of inflammation are used in the treatment of rheumatoid arthritis (RA). The aim of this study was to update a previous systematic review published in 2000. We searched electronic databases (MEDLINE, EMBASE, CISCOM, AMED, CINAHL, Cochrane registers) to June 2007, unrestricted by date or language, and included randomized controlled trials that compared HMPs with inert (placebo) or active controls in patients with rheumatoid arthritis. Five reviewers contributed to data extraction. Disagreements were discussed and resolved by consensus with reference to Cochrane guidelines and advice from the Cochrane Collaboration. Twenty studies (10 identified for this review update, and 10 of the 11 studies of the original review) investigating 14 HMPs were included. Meta-analysis was restricted to data from previous seven studies with oils from borage, blackcurrant and evening primrose containing gamma linolenic acid (GLA). GLA doses equal or higher than 1400 mg/day showed benefit in the alleviation of rheumatic complaints whereas lower doses (∼500 mg) were ineffective. Three studies compared products from Tripterygium wilfordii (thunder god vine) to placebos and returned favorable results but data could not be pooled because the interventions and measures differed. Serious adverse effects occurred in one study. In a follow-up study all side effects were mild to moderate and resolved after the intervention ceased, but time to resolution was variable. Two studies comparing Phytodolor N R to placebo were of limited use because some measures were poorly defined. The remaining studies, each considering differing HMPs, were assessed individually. For most HMPs used in the treatment of RA, the evidence of effectiveness was insufficient to either recommend or discourage their use. Interventions with HMPs containing GLA or Tripterygium wilfordii extract appear to produce therapeutic effects but further investigations are warranted to prove their effectiveness and safety. Copyright © 2009 John Wiley & Sons, Ltd.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/64567/1/3006_ftp.pd

Novel Approach for Emotion Detection and Stabilizing Mental State by Using Machine Learning Techniques

The aim of this research study is to detect emotional state by processing electroencephalography (EEG) signals and test effect of meditation music therapy to stabilize mental state. This study is useful to identify 12 subtle emotions angry (annoying, angry, nervous), calm (calm, peaceful, relaxed), happy (excited, happy, pleased), sad (sleepy, bored, sad). A total 120 emotion signals were collected by using Emotive 14 channel EEG headset. Emotions are elicited by using three types of stimulus thoughts, audio and video. The system is trained by using captured database of emotion signals which include 30 signals of each emotion class. A total of 24 features were extracted by performing Chirplet transform. Band power is ranked as the prominent feature. The multimodel approach of classifier is used to classify emotions. Classification accuracy is tested for K-nearest neighbor (KNN), convolutional neural network (CNN), recurrent neural network (RNN) and deep neural network (DNN) classifiers. The system is tested to detect emotions of intellectually disable people. Meditation music therapy is used to stable mental state. It is found that it changed emotions of both intellectually disabled and normal participants from the annoying state to the relaxed state. A 75% positive transformation of mental state is obtained in the participants by using music therapy. This research study presents a novel approach for detailed analysis of brain EEG signals for emotion detection and stabilize mental state