26 research outputs found
Reducing the Risk of Birds Colliding into Windows: A Practical Guide for Homes and Businesses
This fact sheet explains the problem of birds colliding into windows, why they fly into windows, windows that pose the greatest threat, what you can do to reduce the risk, and what to do if you find an injured bird
Women's Parties: A New Party Family
Womenâs parties have a unique and important role to play in the representation of women and womenâs issues and interests. They are neither a new nor a rare phenomenon and have emerged in a variety of contexts across time and space. And yet we know relatively little about them. This article argues that womenâs parties matter and that the study of womenâs parties matters. We contend that womenâs parties constitute a discrete party family; while there is a diverse range of womenâs parties, they can be viewed as a coherent group with similar origins, ideology, and naming patterns. This article offers the first research framework for the comparative study of womenâs parties. Building our knowledge of womenâs parties, we argue, is important for those interested in gender and politics, particularly those concerned with the representation of womenâs issues and interests
A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting
BACKGROUND: Humans vary in their susceptibility to acquiring Staphylococcus aureus infection, and research suggests that there is a genetic basis for this variability. Several recent genome-wide association studies (GWAS) have identified variants that may affect susceptibility to infectious diseases, demonstrating the potential value of GWAS in this arena. METHODS: We conducted a GWAS to identify common variants associated with acquisition of S. aureus bacteremia (SAB) resulting from healthcare contact. We performed a logistic regression analysis to compare patients with healthcare contact who developed SAB (361 cases) to patients with healthcare contact in the same hospital who did not develop SAB (699 controls), testing 542,410 SNPs and adjusting for age (by decade), sex, and 6 significant principal components from our EIGENSTRAT analysis. Additionally, we evaluated the joint effect of the host and pathogen genomes in association with severity of SAB infection via logistic regression, including an interaction of host SNP with bacterial genotype, and adjusting for age (by decade), sex, the 6 significant principal components, and dialysis status. Bonferroni corrections were applied in both analyses to control for multiple comparisons. RESULTS: Ours is the first study that has attempted to evaluate the entire human genome for variants potentially involved in the acquisition or severity of SAB. Although this study identified no common variant of large effect size to have genome-wide significance for association with either the risk of acquiring SAB or severity of SAB, the variant (rs2043436) most significantly associated with severity of infection is located in a biologically plausible candidate gene (CDON, a member of the immunoglobulin family) and may warrant further study. CONCLUSIONS: The genetic architecture underlying SAB is likely to be complex. Future investigations using larger samples, narrowed phenotypes, and advances in both genotyping and analytical methodologies will be important tools for identifying causative variants for this common and serious cause of healthcare-associated infection