126 research outputs found

    Regional Design Stepping into the Sea

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    Exploring land-sea interactions: Insights for shaping territorial space

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    The interactions between land and sea are fundamental to human wellbeing. Within Europe, the 2014 Directive establishing a framework for maritime spatial planning (MSP Directive), which requires EU coastal member states to have marine spatial plans in place by 2021, also requires that MSP authorities should explicitly take into account land-sea interactions. This has stimulated a new phase of investigation into land-sea interactions in Europe. This paper aims to contribute to marine and coastal planning debates by reflecting on one of these investigations, the Maritime Spatial Planning and Land Sea Interactions (MSP-LSI) project. The paper starts by providing a historical overview of the growing attention being paid to LSI within the context of European policy making. This sets the context for the MSP-LSI project and the approach to exploring land-sea interactions it developed is outlined. The paper then uses examples from the project’s case study investigations to highlight and illustrate some of the wider insights the project revealed, both in relation to the extensive spatial footprint associated with selected maritime sectors and how marine space is being shaped by, and contributing to landward activity and governance agendas. It concludes by presenting a case not only for adopting a ‘one space’ perspective in MSP, but in territorial spatial planning and management regimes more generally.</jats:p

    Diversity Issues in Literacy Teacher Education

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    In this study, the researchers examine how diversity and knowledge about diversity were viewed and integrated into higher education literacy programs. Using online focus groups, we collected information about diversity in literacy at the program and course levels. Literacy teacher educators reported complexities in the preparation of current and future teachers regarding working with diverse learners. The three themes of perspectives and dispositions, curriculum issues and decisions, and outside influences emerged. The researchers recommend that teacher educators find innovative ways to increase teacher education program effectiveness to enhance the dispositions and practices of the teachers whom they prepare where diversity is concerned

    Discovery of <i>Aspergillus frankstonensis</i> sp nov during environmental sampling for animal and human fungal pathogens

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    Invasive fungal infections (IFI) due to species in Aspergillus section Fumigati (ASF), including the Aspergillus viridinutans species complex (AVSC), are increasingly reported in humans and cats. The risk of exposure to these medically important fungi in Australia is unknown. Air and soil was sampled from the domiciles of pet cats diagnosed with these IFI and from a nature reserve in Frankston, Victoria, where Aspergillus viridinutans sensu stricto was discovered in 1954. Of 104 ASF species isolated, 61% were A. fumigatus sensu stricto, 9% were AVSC (A. felis-clade and A. frankstonensis sp. nov.) and 30% were other species (30%). Seven pathogenic ASF species known to cause disease in humans and animals (A. felis-clade, A. fischeri, A. thermomutatus, A. lentulus, A. laciniosus A. fumisynnematus, A. hiratsukae) comprised 25% of isolates overall. AVSC species were only isolated from Frankston soil where they were abundant, suggesting a particular ecological niche. Phylogenetic, morphological and metabolomic analyses of these isolates identified a new species, A. frankstonensis that is phylogenetically distinct from other AVSC species, heterothallic and produces a unique array of extrolites, including the UV spectrum characterized compounds DOLD, RAIMO and CALBO. Shared morphological and physiological characteristics with other AVSC species include slow sporulation, optimal growth at 37°C, no growth at 50°C, and viriditoxin production. Overall, the risk of environmental exposure to pathogenic species in ASF in Australia appears to be high, but there was no evidence of direct environmental exposure to AVSC species in areas where humans and cats cohabitate

    ‘How people from Chinese backgrounds make sense of and respond to experiences of mental distress: Thematic analysis

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    This is the peer reviewed version of the following article: E. Y. W. Yeung, F. Irvine, and K. M. S. Tsang, ‘How people from Chinese backgrounds make sense of and respond to the experiences of mental distress: Thematic analysis’, Journal of Psychiatric and Mental Health Nursing, Vol. 24 (8): 589-599, October 2017, which has been published in final form at https://doi.org/10.1111/jpm.12406. Under embargo. Embargo end date: 3 August 2018. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.Introduction: Late presentation and low utilisation of mental health services are common among Chinese populations. An understanding of their journey towards mental health care helps to identify timely and appropriate intervention. Aim: We aimed to examine how Chinese populations make sense of the experiences of mental distress, and how this understanding influences their pathways to mental health care. Method: We undertook in-depth interviews with fourteen people with mental health problems and sixteen family members. Thematic analysis was used to analyse data. Results / Discussions: Different conceptualisation of mental distress and the stigma attached to mental health problems explained why most participants accessed services at crisis points. Because of mental illness stigma, they were reluctant to seek help outside of the family. Participants used a pragmatic pluralistic approach to incorporate ritual healing and western interventions to manage mental distress as they travelled further on the pathway journey. Families play a key role in the journey and are prepared to visit different parts of the world to seek traditional healers. Implications for practice: Mental health nurses need to adopt a transcultural working approach to address mental health issues so that family will get the support needed to continue their caring role.Peer reviewe

    Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent

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    Prostate cancer (CaP) is the leading cancer among men of African descent in the USA, Caribbean, and Sub-Saharan Africa (SSA). The estimated number of CaP deaths in SSA during 2008 was more than five times that among African Americans and is expected to double in Africa by 2030. We summarize publicly available CaP data and collected data from the men of African descent and Carcinoma of the Prostate (MADCaP) Consortium and the African Caribbean Cancer Consortium (AC3) to evaluate CaP incidence and mortality in men of African descent worldwide. CaP incidence and mortality are highest in men of African descent in the USA and the Caribbean. Tumor stage and grade were highest in SSA. We report a higher proportion of T1 stage prostate tumors in countries with greater percent gross domestic product spent on health care and physicians per 100,000 persons. We also observed that regions with a higher proportion of advanced tumors reported lower mortality rates. This finding suggests that CaP is underdiagnosed and/or underreported in SSA men. Nonetheless, CaP incidence and mortality represent a significant public health problem in men of African descent around the world

    You haven't seen their faces: eugenic national housekeeping and documentary photography in 1930s America

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    This essay explores the relationship between welfare, eugenics and documentary photography during the New Deal in order to explain how a set of government photographs taken by Arthur Rothstein in the Shenandoah became entwined in the rhetorical structure of eugenic ideology. The photographs discussed portray victims of forced sterilization before their incarceration, yet there is no evidence to show that the photographer was aware of, or complicit with, this fact. This essay responds to the questions this raises about the images: what historical and social contingencies were behind their production? What is the relationship between the photographer, the photographs, the New Deal and the subjects depicted? How did efforts to help America's poorest lead to their incarceration and sterilization? Why is the full picture impossible to see? And how do we read and understand them today

    A systematic review of the effectiveness of self-management interventions in people with multiple sclerosis at improving depression, anxiety and quality of life.

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    BACKGROUND: Self-management interventions have become increasingly popular in the management of long-term health conditions; however, little is known about their impact on psychological well-being in people with Multiple Sclerosis (MS). PURPOSE: To examine the effectiveness of self-management interventions on improving depression, anxiety and health related quality of life in people with MS. METHOD: A structured literature search was conducted for the years 2000 to 2016. The review process followed the PRISMA guidelines, and is registered with PROSPERO (no. CRD42016033925). RESULTS: The review identified 10 RCT trials that fulfilled selection criteria and quality appraisal. Self-management interventions improved health-related quality of life in 6 out of 7 studies, with some evidence of improvement in depression and anxiety symptoms. CONCLUSION: Although the results are promising more robust evaluation is required in order to determine the effectiveness of self-management interventions on depression, anxiety and quality of life in people with MS. Evaluation of the data was impeded by a number of methodological issues including incomplete content and delivery information for the intervention and the exclusion of participants representing the disease spectrum. Recommendations are made for service development and research quality improvement

    Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination

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    Genome rearrangements often result from non-allelic homologous recombination (NAHR) between repetitive DNA elements dispersed throughout the genome. Here we systematically analyze NAHR between Ty retrotransposons using a genome-wide approach that exploits unique features of Saccharomyces cerevisiae purebred and Saccharomyces cerevisiae/Saccharomyces bayanus hybrid diploids. We find that DNA double-strand breaks (DSBs) induce NAHR–dependent rearrangements using Ty elements located 12 to 48 kilobases distal to the break site. This break-distal recombination (BDR) occurs frequently, even when allelic recombination can repair the break using the homolog. Robust BDR–dependent NAHR demonstrates that sequences very distal to DSBs can effectively compete with proximal sequences for repair of the break. In addition, our analysis of NAHR partner choice between Ty repeats shows that intrachromosomal Ty partners are preferred despite the abundance of potential interchromosomal Ty partners that share higher sequence identity. This competitive advantage of intrachromosomal Tys results from the relative efficiencies of different NAHR repair pathways. Finally, NAHR generates deleterious rearrangements more frequently when DSBs occur outside rather than within a Ty repeat. These findings yield insights into mechanisms of repeat-mediated genome rearrangements associated with evolution and cancer
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