416 research outputs found

    Information and Particle Physics

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    Information measures for relativistic quantum spinors are constructed to satisfy various postulated properties such as normalisation invariance and positivity. Those measures are then used to motivate generalised Lagrangians meant to probe shorter distance physics within the maximum uncertainty framework. The modified evolution equations that follow are necessarily nonlinear and simultaneously violate Lorentz invariance, supporting previous heuristic arguments linking quantum nonlinearity with Lorentz violation. The nonlinear equations also break discrete symmetries. We discuss the implications of our results for physics in the neutrino sector and cosmology

    A late medieval warm period in the Southern Ocean as a delayed response to external forcing?

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    International audienceOn the basis of long simulations performed with a three‐dimensional climate model, we propose an interhemispheric climate lag mechanism, involving the long‐term memory of deepwater masses. Warm anomalies, formed in the North Atlantic when warm conditions prevail at surface, are transported by the deep ocean circulation towards the Southern Ocean. There, the heat is released because of large scale upwelling, maintaining warm conditions and inducing a lagged response of about 150 years compared to the Northern Hemisphere. Model results and observations covering the first half of the second millenium suggest a delay between the temperature evolution in the Northern Hemisphere and in the Southern Ocean. The mechanism described here provides a reasonable hypothesis to explain such an interhemipsheric lag

    Environmental and Oceanographic Conditions at the Continental Margin of the Central Basin, Northwestern Ross Sea (Antarctica) since the Last Glacial Maximum

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    The continental margin is a key area for studying the sedimentary processes related to the advance and retreat of the Ross Ice Shelf (Antarctica); nevertheless, much remains to be investigated. The aim of this study is to increase the knowledge of the last glacial/deglacial dynamics in the Central Basin slope–basin system using a multidisciplinary approach, including integrated sedimentological, micropaleontological and tephrochronological information. The analyses carried out on three box cores highlighted sedimentary sequences characterised by tree stratigraphic units. Collected sediments represent a time interval from 24 ka Before Present (BP) to the present time. Grain size clustering and data on the sortable silt component, together with diatom, silicoflagellate and foraminifera assemblages indicate the influence of the ice shelf calving zone (Unit 1, 24–17 ka BP), progressive receding due to Circumpolar Deep Water inflow (Unit 2, 17–10.2 ka BP) and (Unit 3, 10.2 ka BP–present) the establishment of seasonal sea ice with a strengthening of bottom currents. The dominant and persistent process is a sedimentation controlled by contour currents, which tend to modulate intensity in time and space. A primary volcanic ash layer dated back at around 22 ka BP is correlated with the explosive activity of Mount Rittmann

    Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia

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    Background: Plasmodium falciparum malaria is one of the most widespread parasitic infections in humans and remains a leading global health concern. Malaria elimination efforts are threatened by the emergence and spread of resistance to artemisinin-based combination therapy, the first-line treatment of malaria. Promising molecular markers and pathways associated with artemisinin drug resistance have been identified, but the underlying molecular mechanisms of resistance remains unknown. The genomic data from early period of emergence of artemisinin resistance (2008–2011) was evaluated, with aim to define k13 associated genetic background in Cambodia, the country identified as epicentre of anti-malarial drug resistance, through characterization of 167 parasite isolates using a panel of 21,257 SNPs. Results: Eight subpopulations were identified suggesting a process of acquisition of artemisinin resistance consistent with an emergence-selection-diffusion model, supported by the shifting balance theory. Identification of population specific mutations facilitated the characterization of a core set of 57 background genes associated with artemisinin resistance and associated pathways. The analysis indicates that the background of artemisinin resistance was not acquired after drug pressure, rather is the result of fixation followed by selection on the daughter subpopulations derived from the ancestral population. Conclusions: Functional analysis of artemisinin resistance subpopulations illustrates the strong interplay between ubiquitination and cell division or differentiation in artemisinin resistant parasites. The relationship of these pathways with the P. falciparum resistant subpopulation and presence of drug resistance markers in addition to k13, highlights the major role of admixed parasite population in the diffusion of artemisinin resistant background. The diffusion of resistant genes in the Cambodian admixed population after selection resulted from mating of gametocytes of sensitive and resistant parasite populations. (Résumé d'auteur

    Last Glacial Maximum to Holocene paleoceanography of the northwestern Ross Sea inferred from sediment core geochemistry and micropaleontology at Hallett Ridge

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    During the Late Pleistocene Holocene, the Ross Sea Ice Shelf exhibited strong spatial variability in relation to the atmospheric and oceanographic climatic variations. Despite being thoroughly investigated, the timing of the ice sheet retreat from the outer continental shelf since the Last Glacial Maximum (LGM) still remains controversial, mainly due to a lack of sediment cores with a robust chronostratigraphy. For this reason, the recent recovery of sediments containing a continuous occurrence of calcareous foraminifera provides the important opportunity to create a reliable age model and document the early deglacial phase in particular. Here we present a multiproxy study from a sediment core collected at the Hallett Ridge (1800 m of depth), where significant occurrences of calcareous planktonic and benthic foraminifera allow us to document the first evidence of the deglaciation after the LGM at about 20.2 ka. Our results suggest that the co-occurrence of large Neogloboquadrina pachyderma tests and abundant juvenile forms reflects the beginning of open-water conditions and coverage of seasonal sea ice. Our multiproxy approach based on diatoms, silicoflagellates, carbon and oxygen stable isotopes on N. pachyderma, sediment texture, and geochemistry indicates that abrupt warming occurred at approximately 17.8 ka, followed by a period of increasing biological productivity. During the Holocene, the exclusive dominance of agglutinated benthic foraminifera suggests that dissolution was the main controlling factor on calcareous test accumulation and preservation. Diatoms and silicoflagellates show that ocean conditions were variable during the middle Holocene and the beginning of the Neoglacial period at around 4 ka. In the Neoglacial, an increase in sand content testifies to a strengthening of bottom-water currents, supported by an increase in the abundance of the tycopelagic fossil diatom Paralia sulcata transported from the coastal regions, while an increase in ice-rafted debris suggests more glacial transport by icebergs

    Determination of the Upper Critical Field of a Single Crystal LiFeAs: The Magnetic Torque Study up to 35 Tesla

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    We report on the upper critical field B_c2 of a superconducting LiFeAs single crystal with T_c~16 K, determined from magnetic torque measurements in dc-magnetic fields up to 35 T and at temperatures down to 0.3 K. B_c2 at 0.3 K is obtained to be 26.4 T and 15.5 T for the applied field B_a||ab and B_a||c, respectively. The anisotropy parameter Γ\Gamma=Bc2ab/Bc2cB_c2^ab / B_c2^c is ~ 3 at T_c and decreases to 1.7 as T0T \rightarrow 0, showing rather isotropic superconductivity. While B_c2 is orbitally-limited for B_a||c, the spin-paramagnetic effect is evident in the temperature dependence of B_c2 for B_a||abComment: 4 pages, 4 figures, revised version to be published in J. Phys. Soc. Jpn. as a letter articl
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