165 research outputs found
Synthesising, using, and correcting for telluric features in high-resolution astronomical spectra
We present a technique to synthesise telluric absorption and emission
features both for in-situ wavelength calibration and for their removal from
astronomical spectra. While the presented technique is applicable for a wide
variety of optical and infrared spectra, we concentrate in this paper on
selected high-resolution near-infrared spectra obtained with the CRIRES
spectrograph to demonstrate its performance and limitation. We find that
synthetic spectra reproduce telluric absorption features to about 2%, even
close to saturated line cores. Thus, synthetic telluric spectra could be used
to replace the observation of telluric standard stars, saving valuable
observing time. This technique also provides a precise in-situ wavelength
calibration, especially useful for high-resolution near-infrared spectra in the
absence of other calibration sources.Comment: 11 pages, 11 figures, accepted for publication in A&A (updated
version
Post-traumatic stress disorder following childbirth: an update of current issues and recommendations for future research
Objective:
This paper aimed to report the current status of research in the field of post-traumatic stress disorder following childbirth (PTSD FC), and to update the findings of an earlier 2008 paper.
Background:
A group of international researchers, clinicians and service users met in 2006 to establish the state of clinical and academic knowledge relating to PTSD FC. A paper identified four key areas of research knowledge at that time.
Methods:
Fourteen clinicians and researchers met in Oxford, UK to update the previously published paper relating to PTSD FC. The first part of the meeting focused on updating the four key areas identified previously, and the second part on discussing new and emerging areas of research within the field.
Results:
A number of advances have been made in research within the area of PTSD FC. Prevalence is well established within mothers, several intervention studies have been published, and there is growing interest in new areas: staff and pathways; prevention and early intervention; impact on families and children; special populations; and post-traumatic growth.
Conclusion:
Despite progress, significant gaps remain within the PTSD FC knowledge base. Further research continues to be needed across all areas identified in 2006, and five areas were identified which can be seen as ‘new and emerging’. All of these new areas require further extensive research. Relatively little is still known about PTSD FC
The Landscape Archaeology of Knettishall Heath, Suffolk and its Implications
This paper briefly describes the results of archaeological fieldwork carried out in an area of heathland, currently managed as a nature reserve, in East Anglia. Although the earthworks recorded are for the most part unremarkable, they demonstrate the variety and intensity of human exploitation which shaped this ‘traditionally managed’ habitat. They also serve to emphasise the extent to which modern conservation management can radically change the long-term character of individual places
Altered Intrinsic Functional Brain Architecture in Children at Familial Risk of Major Depression
Background Neuroimaging studies of patients with major depression have revealed abnormal intrinsic functional connectivity measured during the resting state in multiple distributed networks. However, it is unclear whether these findings reflect the state of major depression or reflect trait neurobiological underpinnings of risk for major depression. Methods We compared resting-state functional connectivity, measured with functional magnetic resonance imaging, between unaffected children of parents who had documented histories of major depression (at-risk, n = 27; 8–14 years of age) and age-matched children of parents with no lifetime history of depression (control subjects, n = 16). Results At-risk children exhibited hyperconnectivity between the default mode network and subgenual anterior cingulate cortex/orbital frontal cortex, and the magnitude of connectivity positively correlated with individual symptom scores. At-risk children also exhibited 1) hypoconnectivity within the cognitive control network, which also lacked the typical anticorrelation with the default mode network; 2) hypoconnectivity between left dorsolateral prefrontal cortex and subgenual anterior cingulate cortex; and 3) hyperconnectivity between the right amygdala and right inferior frontal gyrus, a key region for top-down modulation of emotion. Classification between at-risk children and control subjects based on resting-state connectivity yielded high accuracy with high sensitivity and specificity that was superior to clinical rating scales. Conclusions Children at familial risk for depression exhibited atypical functional connectivity in the default mode, cognitive control, and affective networks. Such task-independent functional brain measures of risk for depression in children could be used to promote early intervention to reduce the likelihood of developing depression
Exoplanet Characterization and the Search for Life
Over 300 extrasolar planets (exoplanets) have been detected orbiting nearby
stars. We now hope to conduct a census of all planets around nearby stars and
to characterize their atmospheres and surfaces with spectroscopy. Rocky planets
within their star's habitable zones have the highest priority, as these have
the potential to harbor life. Our science goal is to find and characterize all
nearby exoplanets; this requires that we measure the mass, orbit, and
spectroscopic signature of each one at visible and infrared wavelengths. The
techniques for doing this are at hand today. Within the decade we could answer
long-standing questions about the evolution and nature of other planetary
systems, and we could search for clues as to whether life exists elsewhere in
our galactic neighborhood.Comment: 7 pages, 2 figures, submitted to Astro2010 Decadal Revie
Modern optical astronomy: technology and impact of interferometry
The present `state of the art' and the path to future progress in high
spatial resolution imaging interferometry is reviewed. The review begins with a
treatment of the fundamentals of stellar optical interferometry, the origin,
properties, optical effects of turbulence in the Earth's atmosphere, the
passive methods that are applied on a single telescope to overcome atmospheric
image degradation such as speckle interferometry, and various other techniques.
These topics include differential speckle interferometry, speckle spectroscopy
and polarimetry, phase diversity, wavefront shearing interferometry,
phase-closure methods, dark speckle imaging, as well as the limitations imposed
by the detectors on the performance of speckle imaging. A brief account is
given of the technological innovation of adaptive-optics (AO) to compensate
such atmospheric effects on the image in real time. A major advancement
involves the transition from single-aperture to the dilute-aperture
interferometry using multiple telescopes. Therefore, the review deals with
recent developments involving ground-based, and space-based optical arrays.
Emphasis is placed on the problems specific to delay-lines, beam recombination,
polarization, dispersion, fringe-tracking, bootstrapping, coherencing and
cophasing, and recovery of the visibility functions. The role of AO in
enhancing visibilities is also discussed. The applications of interferometry,
such as imaging, astrometry, and nulling are described. The mathematical
intricacies of the various `post-detection' image-processing techniques are
examined critically. The review concludes with a discussion of the
astrophysical importance and the perspectives of interferometry.Comment: 65 pages LaTeX file including 23 figures. Reviews of Modern Physics,
2002, to appear in April issu
Spatial Commuting Patterns of German Regional Labour Markets: A Sustainability Perspective
Advancing the Selection of Neurodevelopmental Measures in Epidemiological Studies of Environmental Chemical Exposure and Health Effects
With research suggesting increasing incidence of pediatric neurodevelopmental disorders, questions regarding etiology continue to be raised. Neurodevelopmental function tests have been used in epidemiology studies to evaluate relationships between environmental chemical exposures and neurodevelopmental deficits. Limitations of currently used tests and difficulties with their interpretation have been described, but a comprehensive critical examination of tests commonly used in studies of environmental chemicals and pediatric neurodevelopmental disorders has not been conducted. We provide here a listing and critical evaluation of commonly used neurodevelopmental tests in studies exploring effects from chemical exposures and recommend measures that are not often used, but should be considered. We also discuss important considerations in selecting appropriate tests and provide a case study by reviewing the literature on polychlorinated biphenyls
A Fluorescent Glycolipid-Binding Peptide Probe Traces Cholesterol Dependent Microdomain-Derived Trafficking Pathways
10.1371/journal.pone.0002933PLoS ONE38
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