399 research outputs found
Teaching Mental Health Discourse
In this article, we present an approach to teaching a course on Interpreting Mental Health Discourse, based on our experiences in developing and teaching this course at Gallaudet University. We report on how faculty from two departments, Interpreting and Counseling, worked together with the goal of providing students in the Interpreting program with knowledge and skill-building opportunities for interpreting mental health discourse. We include examples from the course content and format, and suggestions for using available resources, as well as a discussion of what worked well and what did not. The article is a valuable resource for interpreter educators who are considering developing a similar course, and also for interpreters who are interested in improving their understanding of interpreting mental health discourse
Economic resilience and crowdsourcing platforms
The increased interdependence and complexity of modern societies have increased the need to involve all members of a community into solving problems. In times of great uncertainty, when communities face threats of different kinds and magnitudes, the traditional top-down approach where government provides solely for community wellbeing is no longer plausible. Crowdsourcing has emerged as an effective means of empowering communities with the potential to engage individuals in innovation, self-organization activities, informal learning, mutual support, and political action that can all lead to resilience. However, there remains limited resource on the topic. In this paper, we outline the various forms of crowdsourcing, economic and community resilience, crowdsourcing and economic resilience, and a case study of the Nepal earthquake. his article presents an exploratory perspective on the link can be found between crowdsourcing and economic resilience. It introduces and describes a framework that can be used to study the impact of crowdsourcing initiatives for economic resilience by future research. An initial a set of indicators to be used to measure the change in the level of resilience is presented.info:eu-repo/semantics/publishedVersio
Soluble LAG-3 binding to cancer cells - influence of cell types, MHC class II and lipid rafts
Interaction of immunoinhibitory molecules, lymphocyte activating gene-3 (LAG-3) and programmed cell death protein-1 (PD-1) on tumor infiltrating lymphocytes with their respective ligands, contributes to an exhausted immune phenotype. However, soluble LAG-3 (sLAG-3) enhances immunity by inducing dendritic cell maturation by binding MHC-II associated with lipid rafts.
The first part of this thesis assessed the importance of MHC-II/lipid rafts versus peptide/MHC-II complexes (pMHC-II) as sLAG-3 ligands. Analysis of sLAG-3 binding to B-cell lines was done using flow cytometry. Results indicated stable pMHC-II play a larger role in sLAG-3 binding than incorporation of pMHC-II in lipid rafts.
sLAG-3 binding, MHC-II, CD59 and PD-L1 were assessed by flow cytometry on IFN-γ treated melanoma cell line (MDA-MB-435) and different breast cancer cell lines (BCCL). Lipid raft disruptor, methyl-B-cyclodextrin was used to treat cell lines to determine if LAG-3 binding was affected by lipid rafts. Cell lines were MHC-II⁺ and PD-L1⁺, but only MDA-MB-435 bound sLAG3. Deficient LAG-3 binding to BCCL could not be explained by HLA-DM or lipid raft deficiency. Lipid raft disruption increased sLAG-3 binding, this could not be explained by MHC-II or CD59. This suggests that lipid raft disruption may expose MHC-II and other ligands to promote sLAG-3 binding.
Altogether, results indicate LAG-3 binding is cell-context dependent and more complex than simply binding p/MHC-II complexes, preferentially located in lipid rafts
The Role Online Television Viewing has in the Future of Television and Audience Measurement
This study examines major issues facing the television industry, particularly those affecting audience measurements along with issues surrounding Nielsen. Most of this research was done online, through books and in conversation with various television executives. This information is constantly changing therefore most of the research relied heavily on things being published online and interviews with television executives from major broadcast television networks.M.S., Television Management -- Drexel University, 201
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Building Strong Systems of Support for Young Children's Mental Health: Key Strategies for States and a Planning Tool
Young children's mental health provides an essential foundation for early learning and development. In the early years, children's mental health can be seen in a wide range of behaviors that promote engagement in social relationships and learning. An infant who joyfully participates in "conversation" with parents is acquiring a capacity for strong social relationships while learning language and the patterns of communication. A toddler shows positive mental health by actively investigating her environment while gaining new cognitive and motor skills during play and exploration. A preschooler who helps his friend build a robot, shares his favorite markers, and rebuilds his block tower after it tumbles is learning social and problem-solving skills that will fuel learning in preschool and beyond. In sum, young children's "mental health" refers to emotional wellbeing and positive social development from birth through age 5. Young children with mental health problems miss out on developmental experiences that promote early learning. The behavior problems of some children result in actual expulsion from early care and education settings. For other children, mental health problems and challenging behavior may limit positive engagement in learning by contributing to conflictual relationships with teachers and classmates. Young children experiencing sadness or anxiety may find it hard to fully participate in growth-promoting play and learning activities. At home, young children with problem behaviors may be caught in a cycle of negative interactions with parents that disrupt a nurturing parent-child relationship and further limit support for the child's healthy development. Recent estimates suggest that between nine and 14 percent of children under age experience emotional and behavioral problems. The prevalence of mental health problems is markedly higher for children in families facing economic hardship and other stressful circumstances, such as maternal depression. In the absence of interventions, mental health conditions that emerge in the early years tend to persist and interfere with healthy development and learning. State leaders increasingly recognize the critical link between young children's mental health and later social adjustment and success in school. In recent years, states have begun to develop new policies and programs that help establish supports for young children's mental health across a wide range of settings, including pediatric offices and community clinics, early childhood and home-visiting programs, and child welfare agencies. These efforts focus on promoting positive mental health, preventing potential mental health problems, and treating identified delays or difficulties in social-emotional development. Many states' efforts include the use of evidence-based models and training experiences for service providers to increase their knowledge and skills. Part I of this report describes key strategies that should be part of a comprehensive system of supports for young children's mental health and examples from states that are developing and implementing them. These strategies are: promoting early childhood mental health (ECMH) in home visiting and parenting programs; enhancing supports for ECMH in early care and education programs; screening parents for depression; screening children for social-emotional problems; developing a better-trained workforce to address the social-emotional needs of young children; using evidence-based practices and evaluation to promote effective ECMH programs; and supporting the well-being of exceptionally vulnerable children. Part II of this report presents a simple tool that state planners can use for two purposes: 1) to assess the current status of the state's ECMH supports; and 2) to plan for specific enhancements in the state's current system, including expansion of certain ECMH strategies, such as child screening or training for early childhood teachers, and improvements in the quality of interventions. Since the creation of strong systems of ECMH supports requires collaboration among multiple agencies and programs, this tool may be especially useful for Early Childhood Advisory Councils, Early Childhood Comprehensive Systems initiatives, and similar state-level planning entities that bring together leaders from different sectors
Factors Associated With Delaying Medical Care: Cross-Sectional Study of Nebraska Adults
BACKGROUND: Delayed medical care may result in adverse health outcomes and increased cost. Our purpose was to identify factors associated with delayed medical care in a primarily rural state.
METHODS: Using a stratified random sample of 5,300 Nebraska households, we conducted a cross-sectional mailed survey with online response option (27 October 2020 to 8 March 2021) in English and Spanish. Multiple logistic regression models calculated adjusted odds ratios (aOR) and 95% confidence intervals.
RESULTS: The overall response rate was 20.8% (n = 1,101). Approximately 37.8% of Nebraskans ever delayed healthcare (cost-related 29.7%, transportation-related 3.7%), with 22.7% delaying care in the past year (10.1% cost-related). Cost-related ever delay was associated with younger age [\u3c 45 years aOR 6.17 (3.24-11.76); 45-64 years aOR 2.36 (1.29-4.32)], low- and middle-income [\u3c 50,000-50,000 [aOR 8.44 (2.18-32.63)]. Those who did not have a primary care provider were 80% less likely to have transportation delays [aOR 0.20 (0.05-0.80)].
CONCLUSIONS: Delayed care affects more than one-third of Nebraskans, primarily due to financial concerns, and impacting low- and middle-income families. Transportation-related delays are associated with more indicators of low socio-economic status. Policies targeting minorities and those with low- and middle-income, such as Medicaid expansion, would contribute to addressing disparities resulting from delayed care
Hydrography, nutrients, and carbon pools in the Pacific sector of the Southern Ocean: Implications for carbon flux
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We investigated the hydrography, nutrients, and dissolved and particulate carbon pools in the western Pacific sector of the Antarctic Circumpolar Current (ACC) during austral summer 1996 to assess the region\u27s role in the carbon cycle. Low f CO2 values along two transects indicated that much of the study area was a sink for atmospheric CO2. The f CO2 values were lowest near the Polar Front (PF) and the Subtropical Front (STF), concomitant with maxima of chlorophyll a and particulate and dissolved organic carbon. The largest biomass accumulations did not occur at fronts, which had high surface geostrophic velocities (20–51 cm s−1), but in relatively low velocity regions near fronts or in an eddy. Thus vertical motion and horizontal advection associated with fronts may have replenished nutrients in surface waters but also dispersed phytoplankton. Although surface waters north of the PF have been characterized as a “high nutrient‐low chlorophyll” region, low silicic acid (Si) concentrations (2–4 μM ) may limit production of large diatoms and therefore the potential carbon flux. Low concentrations (4–10 μM Si) at depths of winter mixing constrain the level of Si replenishment to surface waters. It has been suggested that an increase in aeolian iron north of the PF may increase primary productivity and carbon export. Our results, however, indicate that while diatom growth and carbon export may be enhanced, the extent ultimately would be limited by the vertical supply of Si. South of the PF, the primary mechanism by which carbon is exported to deep water appears to be through diatom flux. We suggest that north of the PF, particulate and dissolved carbon may be exported primarily to intermediate depths through subduction and diapycnal mixing associated with Subantarctic Mode Water and Antarctic Intermediate Water formation. These physical‐biological interactions and Si dynamics should be included in future biogeochemical models to provide a more accurate prediction of carbon flux
Contextual Challenges for Crisis Support in the Immediate Aftermath of Major Incidents in the UK
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