13 research outputs found
Movement and residency patterns of reef manta rays Mobula alfredi in the Amirante Islands, Seychelles
- Publication venue
- 'Inter-Research Science Center'
- Publication date
- Field of study
Platelet and Granulocyte Transfusions in Cancer Patients
- Author
- A Katz
- A Katz
- AEG Borne von dem
- AJ Roy
- AM Prince
- AS Ungerleider
- B Kotelba-Witkowska
- B Swerdlow
- BK Kim
- BW Dana
- C Vallejos
- CA Jongh De
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CA Schiffer
- CD Buckner
- CG Zaroulis
- CG Zaroulis
- CR Rinaldo Jr
- CR Valeri
- D Cohen
- D Green
- D Klatzman
- DB Cines
- DC Dale
- DD Karp
- DE Hogge
- DE Hogge
- DG Wright
- DH Buchholz
- DJ Filip
- DJ Higby
- DJ Higby
- DJ Winston
- DJ Winston
- DJ Winston
- DJ Winston
- DM Meyer
- DR Boggs
- DR Boggs
- DW Huestis
- DW Schoendorfer
- ED Thomas
- EF Winton
- EJ Freireich
- EJ Freireich
- EL Snyder
- EL Snyder
- EORTC International Antimicrobial Therapy Project Group
- F Tejada
- FHJ Claas
- FWA Verheugt
- G Dayian
- GA Rock
- GE Cartwright
- GT Archer
- H Alter
- H Braine
- H-P Lohrmann
- HJ Eyre
- HK Gralnick
- HM Lazarus
- HS Chow
- IM Goldstein
- IO Szymanski
- J Aisner
- J Dausset
- J Hersman
- J Klastersky
- J McCullough
- J McCullough
- J McCullough
- JB Alavi
- JC Wade
- JD Meyers
- JE Howard
- JG Eernisse
- JL Gomez-Villagran
- JM Ford
- JM Heal
- JP Dutcher
- JP Dutcher
- JP Dutcher
- JP Dutcher
- JP Dutcher
- JP Dutcher
- JP Dutcher
- JP Dutcher
- JP Hester
- JP Hester
- JR Bove
- JW Athens
- JW Curran
- K Sintnicolaas
- KB McCredie
- KK Mittal
- KK Wu
- LA Boxer
- LA Gaydos
- LA Harker
- LJ Love
- LJ Love
- MA Westrick
- MJ Keating
- ML Thakur
- ML Thakur
- MR O’Donnell
- MT Osterholm
- N Blumberg
- ND Kalinin
- NL Ascher
- NR Shulman
- P Herve
- P Lalezari
- P Mannoni
- PA Daly
- PA Daly
- PA Daly
- PA Daly
- PL Weiden
- PM Feorino
- RA Clift
- RA Kahn
- RA Yankee
- RB Epstein
- RC Gallo
- RD Aach
- RD Diamond
- RE Dinsmore
- RF Applebaum
- RF Reiss
- RG Graw
- RG Graw
- RG Strauss
- RH Herzig
- RH Herzig
- RJ Duquesnoy
- RJ Duquesnoy
- RJ Duquesnoy
- RM Lowenthal
- RT Silver
- S Holme
- S Murphy
- S Murphy
- S Murphy
- S Murphy
- S Murphy
- SJ Slichter
- SJ Slichter
- ST Sandler
- T Han
- T Hasegawa
- T Nagasawa
- TL Simon
- TS Kickler
- TV Holohan
- V Flieder von
- WL Bayer
- WR Vogler
- WW Duke
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1986
- Field of study
Physician Risk Assessment Knowledge Regarding BRCA Genetics Testing
- Author
- Bhuma Krishnamachari
- Brian Harper
- Brookshield Laurent
- CA Bellcross
- CF Prochniak
- David Tegay
- HD Nelson
- HS Vig
- IS Fentiman
- Jason Cohn
- KR Blazer
- L Wideroff
- M Epplein
- M Kriege
- MB Daly
- MC King
- MF Myers
- Min-Kyung Jung
- NL Keating
- OI Olopade
- R Kliztman
- R Siegel
- SG Gabram
- Sharon Koehler
- ST Vadaparampil
- SU Dhar
- T Pal
- TR Rebbeck
- VA Moyer
- Vivian Chan
- William Blazey
- YC Tai
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Worse Breast Cancer Outcomes for Southern Nevadans, Filipina and Black Women
- Author
- A Bleyer
- A Dehal
- AA Onitilo
- American Cancer Society
- B Daly
- BE Hillner
- CA Clarke
- Carmen P. Ponce
- DS Chan
- Erin N. Kobetz
- F Wang
- I Corazziari
- J Iqbal
- JH Silber
- JP Berz
- KA Skinner
- Karen E. Callahan
- M McCracken
- MJ Lund
- N Hébert-Croteau
- NA Chatterjee
- Nevena Cvijetic
- NL Keating
- NT Van Ravesteyn
- Paulo S. Pinheiro
- PS Pinheiro
- PS Pinheiro
- R Chaudhry
- R Flanagan
- R Smith-Bindman
- Rachel E. Kelly
- RL Siegel
- SL Kwong
- SS Gorin
- SS Lin
- SY Ryu
- T Griswold
- XC Wu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2017
- Field of study
BACKGROUND: Breast cancer is the second deadliest cancer for women in the demographically unique mountainous west state of Nevada. This study aims to accurately characterize breast cancer survival among the diverse women of the flourishing Silver State. METHODS: Nevada Central Cancer Registry data was linked with the National Death Index and the Social Security Administration Masterfile. Overall five-year cause-specific survival, survival stratified by race/ethnicity, and stage-specific survival stratified by region of Nevada were calculated. Adjusted hazard ratios were computed with Cox proportional hazards regression. RESULTS: 11,111 cases of breast cancer were diagnosed from 2003–2010. Overall 5-year breast cancer survival in Nevada was 84.4%, significantly lower than the US, at 89.2%. Black and Filipina women had a higher risk of death than white women. DISCUSSION: Poor survival in the racially and ethnically diverse Las Vegas metropolitan area, with a large foreign-born population, drives Nevada’s low overall survival. System-wide changes are recommended to reduce the racial/ethnic disparities seen for black and Filipina women and improve outcomes for all
Reply to: Shark mortality cannot be assessed by fishery overlap alone
- Author
- Abascal FJ
- Abercrombie DL
- Abrantes K
- Acuña-Marrero D
- Afonso AS
- Afonso P
- Anders D
- Araujo G
- Arauz R
- Bach P
- Barnett A
- Bernal D
- Berumen ML
- Bezerra NPA
- Blaison AV
- Block BA
- Bond ME
- Bonfil R
- Bradford RW
- Braun CD
- Brooks A
- Brooks EJ
- Brown J
- Bruce BD
- Byrne ME
- Campana SE
- Carlisle AB
- Chapman DD
- Chapple TK
- Chisholm J
- Clarke CR
- Clua EG
- Cochran JEM
- Cortés DD
- Couto A
- Crochelet EC
- da Costa I
- Dagorn L
- Daly R
- Doyle TK
- Drew M
- Duffy CAJ
- Erikson T
- Espinoza E
- Ferreira LC
- Ferretti F
- Filmalter JD
- Fischer GC
- Fitzpatrick R
- Fontes J
- Forget F
- Fowler M
- Francis MP
- Gallagher AJ
- Gennari E
- Goldsworthy SD
- Gollock MJ
- Green JR
- Gustafson JA
- Guttridge TL
- Guzman HM
- Hammerschlag N
- Harman L
- Hazin FHV
- Heard M
- Hearn AR
- Holdsworth JC
- Holmes BJ
- Howey LA
- Hoyos M
- Hueter RE
- Humphries NE
- Hussey NE
- Huveneers C
- Irion DT
- Jacoby DMP
- Jewell OJD
- Johnson R
- Jordan LKB
- Joyce W
- Keating Daly CA
- Ketchum JT
- Klimley AP
- Kock AA
- Koen P
- Ladino F
- Lana FO
- Lea JSE
- Lion SB
- Llewellyn F
- Lyon WS
- MacDonnell A
- Macena BCL
- Marshall H
- McAllister JD
- Mucientes G
- Queiroz N
- Santos AM
- Sequeira AMM
- Vedor M
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 08/07/2021
- Field of study
Global spatial risk assessment of sharks under the footprint of fisheries
- Author
- Abascal FJ
- Abercrombie DL
- Abrantes K
- Acuna-Marrero D
- Afonso AS
- Afonso P
- Anders D
- Araujo G
- Arauz R
- Bach P
- Barnett A
- Bernal D
- Berumen ML
- Bessudo Lion S
- Bezzera NPA
- Blaison AV
- Block BA
- Bond ME
- Bonfil R
- Bradford RW
- Braun CD
- Brooks A
- Brooks EJ
- Brown J
- Bruce BD
- Byrne ME
- Campana SE
- Carlisle AB
- Chapman DD
- Chapple TK
- Chisholm J
- Clarke CR
- Clua EG
- Cochran JEM
- Couto A
- Crochelet EC
- da Costa I
- Dagorn L
- Daly R
- Devia Cortes D
- Doyle TK
- Drew M
- Duarte CM
- Duffy CAJ
- Eguiluz VM
- Erikson T
- Espinoza E
- Ferreira LC
- Ferretti F
- Fischer GC
- Fitzpatrick R
- Fontes J
- Forget F
- Fowler M
- Francis MP
- Gallagher AJ
- Gennari E
- Goldsworthy SD
- Gollock MJ
- Green JR
- Gustafson JA
- Guttridge TL
- Guzman HR
- Hammerschlag N
- Harcourt R
- Harman L
- Hays GC
- Hazin FHV
- Heard M
- Hearn AR
- Holdsworth JC
- Holmes BJ
- Howey LA
- Hoyos M
- Hueter RE
- Humphries NE
- Hussey NE
- Huveneers C
- Irigoien X
- Irion DT
- Jacoby DMP
- Jewell OJD
- Johnson R
- Jordan LKB
- Jorgensen SJ
- Joyce W
- Keating Daly CA
- Ketchum JT
- Klimley AP
- Kock AA
- Koen P
- Ladino F
- Lana FO
- Lea JSE
- Llewellyn F
- Lyon WS
- MacDonnell A
- Macena BCL
- Marshall H
- McAllister JD
- McAuley R
- Meekan MG
- Meyer MA
- Morris JJ
- Mucientes G
- Nelson ER
- Papastamatiou YP
- Patterson TA
- Penaherrera-Palma C
- Pepperell JG
- Pierce SJ
- Poisson F
- Queiroz N
- Quintero LM
- Richardson AJ
- Rogers PJ
- Rohner CA
- Rowat DRL
- Samoilys M
- Santos AM
- Semmens JM
- Sequeira AMM
- Sheaves M
- Shillinger G
- Shivji M
- Simpson SJ
- Sims DW
- Singh Sarika
- Skomal GB
- Smale MJ
- Snyders LB
- Soler G
- Soria M
- Sousa LL
- Southall EJ
- Stehfest KM
- Stevens JD
- Thorrold SR
- Thums M
- Tolotti MT
- Towner A
- Travassos P
- Tyminski JP
- Vandeperre F
- Vaudo Jj
- Vedor M
- Watanabe YY
- Weber SB
- Wetherbee BM
- White TD
- Williams S
- Zarate PM
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Effective ocean management and the conservation of highly migratory species depend on resolving the overlap between animal movements and distributions, and fishing effort. However, this information is lacking at a global scale. Here we show, using a big-data approach that combines satellite-tracked movements of pelagic sharks and global fishing fleets, that 24% of the mean monthly space used by sharks falls under the footprint of pelagic longline fisheries. Space-use hotspots of commercially valuable sharks and of internationally protected species had the highest overlap with longlines (up to 76% and 64%, respectively), and were also associated with significant increases in fishing effort. We conclude that pelagic sharks have limited spatial refuge from current levels of fishing effort in marine areas beyond national jurisdictions (the high seas). Our results demonstrate an urgent need for conservation and management measures at high-seas hotspots of shark space use, and highlight the potential of simultaneous satellite surveillance of megafauna and fishers as a tool for near-real-time, dynamic management
Dynamic genome-scale metabolic modeling of the yeast Pichia pastoris
- Author
- A Graf
- A Maccani
- A Varma
- B Gasser
- B Petersen
- B Tolner
- BCC Research
- BJ Bornstein
- BJ Sánchez
- BJ Sánchez
- BKS Chung
- BO Palsson
- C Landi
- C Rebnegger
- CA Thompson
- D Mattanovich
- D Porro
- D Riesenberg
- D Segrè
- DW Raiford
- E Balsa-Canto
- E Boles
- E Postma
- E Čiplys
- EB Verney
- Eduardo Agosin
- EM Landaw
- F Vargas
- Francisco Saitua
- G Walsh
- GM Stephanopoulos
- H Cheng
- H Kitano
- H Marx
- H Urk van
- HG Holzhütter
- I Thiele
- J Egea
- J Heyland
- J Heyland
- J Nocon
- J Sacher
- J Villadsen
- J Villadsen
- J-R Wang
- JH Park
- JL Cereghino
- JL Corchero
- José Ricardo Pérez-Correa
- K Baumann
- K Baumann
- K Höffner
- K Jaqaman
- K Sriram
- L Caspeta
- M a Asadollahi
- M Cárcamo
- M Delic
- M Delic
- M Dragosits
- M Hasslacher
- M Maurer
- M Tomàs-Gamisans
- MA Stephens
- Markets and Markets
- MG West
- N Ferrer-Miralles
- ND Price
- P Çalık
- Paulina Torres
- R Daly
- R Mahadevan
- R Pereira
- R Prielhofer
- R Schuetz
- R Schuetz
- S Becker
- SB Sohn
- SM Keating
- T Masuda
- TW Overton
- V Ciofalo
- V Looser
- X Feng
- Y Morales
- Y Wang
- ZA Irani
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Temporal changes in the gut microbiota in farmed Atlantic cod (Gadus morhua) outweigh the response to diet supplementation with macroalgae
- Author
- A Amaretti
- A Daly
- A Dimitroglou
- A McKenna
- A Mukherjee
- A Soler-Vila
- AA Adeoye
- AA Smith
- AB Walker
- AB Walker
- AHL Wan
- AHL Wan
- AHL Wan
- AJ Verster
- AK Ray
- AO Kasumyan
- AP Masella
- AR Desai
- B Björnsson
- B Raskovic
- C Drieschner
- C Gauchotte-Lindsay
- C Keating
- C Quast
- CA Schneider
- CFC Lanes
- D Pauly
- DAJ Stone
- DC Watson
- DM Klurfeld
- E Hernández-Garibay
- E Nikouli
- EA Wassef
- EP Ames
- F Rohart
- FAO
- G Baeverfjord
- GJ Edgar
- GM King
- H Liu
- H Zhang
- HC Ingerslev
- HJ Flint
- I Diler
- I Kushkevych
- ICES
- ICES
- ICES
- ICES
- IM Friberg
- J Fleurence
- J Jalanka-Tuovinen
- J Oksanen
- J-B Xiong
- JG Caporaso
- JG Caporaso
- JH Xia
- JL Darcy
- JL Waters
- JS Johnson
- K Gajardo
- K Katoh
- KT Tran-Ngoc
- LMP Valente
- LMP Valente
- M Bolton-Warberg
- M Booman
- M Ghanbari
- M Jaffa
- M Sakthivel
- M Sandri
- M Seppola
- M Soltani
- M Springmann
- MI Love
- ML Palomares
- MS Azaza
- MS Llewellyn
- MT Alou
- NL Garneau
- OS Kjesbu
- PJ McMurdie
- PJ Wright
- R Harvey
- R Pereira
- RC Edgar
- RC Edgar
- RH Thurstan
- RI Griffiths
- RM Cook
- S Egerton
- S Egerton
- S Gupta
- S Kautz
- S Kong
- S Moutinho
- S Razin
- SA Shetty
- SBM Kraak
- SK Goffredi
- T Li
- TR Core
- V Lecomte
- W Meyerhof
- WB Perry
- WE Holben
- X-Q Li
- Y Hassanzadeh
- Y Yamazaki
- Y Yone
- ZSL Foster
- Å Krogdahl
- Ö Yıldırım
- ØJ Korsøen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Purinergic signalling in the urinary tract in health and disease
- Author
- A Ahluwalia
- A Albino-Teixeira
- A Apostolidis
- A Apostolidis
- A Atala
- A Athanasopoulos
- A Charrua
- A Charrua
- A Chaudhry
- A Coelho
- A Dagnino-Acosto
- A Garcia-Pascual
- A Johns
- A Johns
- A Kageyama
- A Labadia
- A Lundin
- A Mattiasson
- A Munoz
- A Munoz
- A Munoz
- A Munoz
- A Nergårdh
- A Shafik
- A Yoshida
- AA Hawranko
- AB MacDermott
- AC Buck
- AC Fabiyi
- AD Brown
- AD Hoyes
- AD Hoyes
- AD Michel
- AE Canda
- AE Canda
- AF Brading
- AF Brading
- AG Santoso
- AK Batra
- AK Batra
- AM Ryhammer
- AP Ford
- AP Ford
- AR Mastri
- AU Ziganshin
- AU Ziganshin
- AU Ziganshin
- AU Ziganshin
- B Boland
- B Chopra
- B Chopra
- B Conte
- B Eika
- B Koley
- B Sperlágh
- B Uvelius
- B Uvelius
- BA O'Reilly
- BA O'Reilly
- BE Crack
- BF King
- BM Dunning-Davies
- BM Girard
- BP Kropp
- BP Kropp
- BS Pittam
- C Bolego
- C Bolego
- C Boselli
- C Boselli
- C Brown
- C Frimodt-Moller
- C Göcmen
- C Li
- C McDermott
- C Mohlin
- C Morgan
- C Moro
- C Pinna
- C Pinna
- C Pinna
- C Pinna
- C Pinna
- C Pinna
- C Pinna
- C Pinna
- C Roza
- C Sjögren
- C Sjögren
- C Sjögren
- C Sjögren
- C Turan
- C Velasco
- C Vial
- C Wu
- C Wu
- C Wu
- C Wu
- CA Buffington
- CA Maggi
- CA Maggi
- CA Maggi
- CA Maggi
- CA Maggi
- CA Maggi
- CA Maggi
- CA Maggi
- CA Walsh
- CG Acevedo
- CG Acevedo
- CG Acevedo
- CG Acevedo
- CGA Persson
- CH Fry
- CH Fry
- CH Fry
- CH Fry
- CH Hoyle
- CH Hoyle
- CH Jiang
- CH Yeh
- CHV Hoyle
- CHV Hoyle
- CHV Hoyle
- CHV Hoyle
- CHV Hoyle
- CHV Hoyle
- CJ Fowler
- CJ Fowler
- CJ Fowler
- CJ Fowler
- CJ Gilpin
- CJ McCarthy
- CJ Nile
- CM Brady
- CM Brown
- CP Smith
- CP Smith
- CP Smith
- CS Iosif
- D Daly
- D Ferguson
- D Giglio
- D Giglio
- D Hudman
- DA Cockayne
- DA Cockayne
- DB Clemow
- DC Kuo
- DC Kuo
- DE Artim
- DE Rapp
- DE Rapp
- DF Weetman
- DIB Kerr
- DJ Smith
- DM Daly
- DM Daly
- DM Dean
- DM Dean
- DM Nance
- DP Müller
- DP Westfall
- DR Ferguson
- DR Tomlinson
- DY Kim
- E Bradley
- E Bradley
- E Meng
- E Meng
- E Meng
- E Messori
- E Senba
- EC Wang
- EJ McGuire
- EM Kudlacz
- EM Kudlacz
- EM Silinsky
- F Buchthal
- F Cervero
- F Daneshgari
- F Grandadam
- F Liu
- FA Kullmann
- FA Kullmann
- FA Kullmann
- FA Stewart
- FG Carpenter
- FH Mumtaz
- FJ Ehlert
- FJ Ehlert
- FV Udoh
- G Apodaca
- G Apodaca
- G Bratslavsky
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G Burnstock
- G D'Agostino
- G Jancsó
- G Ji
- G Karsenty
- G Lambrecht
- G Liu
- G Liu
- G Luheshi
- G McMurray
- GB Chesher
- GE Knight
- GE Knight
- Geoffrey Burnstock
- GF Anderson
- GK Hogaboom
- GM Blackburn
- GM Ghoniem
- GN Luheshi
- GN Luheshi
- GN Luheshi
- GNA Sibley
- GP Sui
- GP Sui
- GW Friedland
- GW Lawrence
- H Akino
- H Atiemo
- H Fuder
- H Fuder
- H Hashitani
- H Hashitani
- H Hashitani
- H Hotta
- H Huddart
- H Ishihama
- H Kura
- H Liu
- H Miller
- H Nakagomi
- H Nakagomi
- H Noto
- H Sann
- H Sann
- H Sann
- H Suzuki
- H Xiao
- H Zimmermann
- H Zimmermann
- H-I Chen
- H-Y Lee
- HD Flood
- HE Moss
- HE Moss
- HE Moss
- HE Webb
- HH Lai
- HJ Piechota
- HS Gill
- HS Moon
- HS Prakasam
- HV Tempest
- I Araki
- I Faerman
- I Kügelgen von
- I Kügelgen von
- I Mackenzie
- I Mackenzie
- I Milicic
- I Rocha
- I Tanaka
- J Dasgupta
- J Dasgupta
- J Ekström
- J Ekström
- J Ekström
- J Ekström
- J Gever
- J Gu
- J Hills
- J Imagawa
- J Lincoln
- J Lincoln
- J Lincoln
- J Mey De
- J Neuhaus
- J Nicholls
- J Nicholls
- J Nicholls
- J Nishiguchi
- J Nishiguchi
- J Pannek
- J Silva
- J Zoubek
- JA Belis
- JA King
- JA Koziol
- JA Ribeiro
- JA Vale
- JD Vaught
- JG Blaivas
- JG Blaivas
- JG Lee
- JG Ouslander
- JH Li
- JJ Wyndaele
- JL Dutton
- JL Morris
- JM Beckel
- JM Laird
- JM Latini
- JM Spitsbergen
- JP Lavelle
- JP Martins
- JR Hindmarsh
- JR Keast
- JR Keast
- JS Peterson
- JS Walczak
- JS Young
- JS Young
- JT Andersen
- JW Downie
- JW Iacovou
- K Dang
- K Dang
- K Erickson
- K Fujii
- K Fujii
- K Fujii
- K Hammer
- K Juszczak
- K Kihara
- K Kishii
- K Mansfield
- K Matsumoto-Miyai
- K Matsumoto-Miyai
- K Obara
- K Persson
- K Shinozuka
- K Sterling
- K Sugaya
- K Sugaya
- K-E Andersson
- K-E Andersson
- K-E Andersson
- K-E Andersson
- K-E Andersson
- KA Hutton
- KD Cotton
- KD McCloskey
- KD McCloskey
- KD Thornbury
- KE Andersson
- KE Andersson
- KE Andersson
- KE Creed
- KE Creed
- KE Creed
- KE Creed
- KE Creed
- KH Moore
- KH Moore
- KN Langley
- KS Thorneloe
- L Barkai
- L Birder
- L Birder
- L Grundy
- L Jörgensen
- L Kasakov
- L Ma
- L Nassauw Van
- L Risholm
- L Rockenbach
- LA Birder
- LA Birder
- LA Birder
- LA Birder
- LA Birder
- LA Birder
- LA Birder
- LA Birder
- LA Meldrum
- LA Welford
- LK Choo
- LK Choo
- LN Kasakov
- LT Breen
- LV Tran
- M Alkondon
- M Barras
- M Bayliss
- M Corsi
- M Dunn
- M Ekman
- M Ellenberg
- M Hashimoto
- M Hernández
- M Hernández
- M Holm-Bentzen
- M Khera
- M Lantéri-Minet
- M Lazzeri
- M Liu
- M Marti-Cabrera
- M Naramatsu
- M Oike
- M Paro
- M Paro
- M Paro
- M Partanen
- M Probst
- M Prosdocimi
- M Saito
- M Saito
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- S Säve
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- Field of study
Mapping the human genetic architecture of COVID-19
- Author
- Abdelrazik M
- Abdullah T
- Abe R
- Abe S
- Abecasis GR
- Abel L
- Abernathy C
- Abraheem A
- Abul-Husn NS
- Acosta-Herrera M
- Acquilini D
- Acquilini D
- Adachi T
- Adachi Y
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- Adeleye O
- Adeniji K
- Adra D
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- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agranoff D
- Agrawal S
- Aguirre LA
- Agwuh K
- Ahmad HF
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- Ail D
- Akeroyd L
- Akhtar MN
- Akhtar S
- Akinkugbe O
- Aksentijevich A
- Al Thani A
- Al-Muftah W
- Al-Sarraj Y
- Alarcon C
- Alarcon-Riquelme ME
- Alasdair F
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- Algera AG
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- Altmueller J
- Alvaro A
- Amar D
- Amin V
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- Ampuero J
- Anan R
- Anania S
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- Anderson J
- Anderson M
- Anderson P
- Anderson S
- Anderson S
- Anderson T
- Ando A
- Andolfo I
- Andrade V
- Andretta F
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- Andreucci E
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- van der Poll T
- van der Valk M
- van Heel D
- van Heel DA
- van Heel DA
- van Koutrik L
- van Mourik N
- Van Singer M
- van Tonder L
- van Uffelen KWJ
- van Vugt M
- Vandernoot I
- Varghese M
- Vari MS
- Varnai R
- Vecchia M
- Vedage D
- Veelo D
- Veerapen K
- Veerapen K
- Veerapen K
- Vehreschild MJGT
- Velho M
- Venkatesh H
- Venturelli S
- Verdugo RA
- Vergori A
- Verlander M
- Verma A
- Verma SS
- Vertue M
- Vertue M
- Verula J
- Verzuri A
- Viala B
- Vigurs C
- Vincent R
- Vincent-Smith L
- Vincenti A
- Viollet RM
- Visuvanathan S
- Vitart V
- Vizcaychipi MP
- Vlaar APJ
- Vochin A
- Voide C
- Voide C
- Volland S
- Vollenweider P
- Vollenweider P
- Von Frenckell C
- von Hohenstaufen K
- von Mering C
- Vonk JM
- Voza A
- Vulesevic B
- Vuylsteke A
- Vuylsteke A
- Wacker EM
- Wackett T
- Wadams B
- Waddington N
- Waddy S
- Wagstaff V
- Waite AAC
- Wakabayashi A
- Wakahara K
- Wake R
- Wakefield P
- Wakinshaw F
- Walden A
- Waldron J
- Walker D
- Walker R
- Walker S
- Walker S
- Walker S
- Wall A
- Walsh T
- Walter J
- Walters RK
- Walton O
- Wang B
- Wang C
- Wang H
- Wang J
- Wang Q
- Wang X
- Wang X
- Ward G
- Ward K
- Ward L
- Ward M
- Warden S
- Warmerdam R
- Warren D
- Washington NL
- Wassall H
- Wasson C
- Watanabe H
- Watanabe K
- Watson E
- Watson G
- Watson J
- Watson N
- Watters M
- Waugh V
- Weaver J
- Webster A
- Webster D
- Webster K
- Wei S
- Weiss ST
- Weldon CH
- Wells C
- Welters I
- Welters ID
- Wendorff M
- Wendt FR
- Wery M
- Wesse T
- West J
- Weston H
- Wham M
- Wheeler M
- Whileman A
- Whitbread J
- White D
- White I
- White K
- White M
- White N
- White S
- Whitehouse T
- Whiteley S
- Whiteside J
- Whittaker P
- Whittington A
- Whittle H
- Whitton C
- Whyte C
- Wicks SJ
- Wienbrandt L
- Wiersinga WJ
- Wijesinghe M
- Wilby E
- Wilcock E
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- Wilcox R
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- Wilding L
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- Wilfling S
- Wilkin F
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- Williams G
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- Williams M
- Williams M
- Williams P
- Williams S
- Williams T
- Willis H
- Wills M
- Willson J
- Wilson A
- Wilson DJ
- Wilson J
- Wilson JF
- Wilson L
- Winchester S
- Winnard S
- Winter-Goodwin B
- Wiselka M
- Wittig M
- Witzke O
- Wolf-Roberts R
- Wolford B
- Wolford B
- Wolterman RA
- Wolverson A
- Wong J
- Wood D
- Wood H-L
- Wood S
- Wood T
- Woodford C
- Woodruff M
- Woods L
- Woodyatt W
- Woolley AE
- Wooton DG
- Working UCLAHATLASDM
- Workman A
- Worner R
- Worsley L
- Wouters D
- Wozniak H
- Wray G
- Wren L
- Wright D
- Wright J
- Wright J
- Wright M
- Wrobel N
- Wrobel N
- Wu Y
- Wulandari R
- Wyllie DH
- Wynter I
- Xavier K
- Xue X
- Yadav A
- Yagi K
- Yamada M
- Yamada Y
- Yamagata K
- Yamasaki M
- Yang G
- Yang J
- Yang Z
- Yaspan B
- Yasui Y
- Yates B
- Yates B
- Yatomi M
- Ye C
- Yengo L
- Yermakovich D
- Yi X
- Yonekawa A
- Yoon H
- Yoon KJ
- Yoshida K
- Yoshida S
- Yoshida S
- Yoshida T
- Yoshihara T
- Yoshiya K
- Yoshiyama T
- Youlton N
- Younes SE
- Young P
- Yun N
- Zak A
- Zaki A
- Zambon M
- Zamikula J
- Zanella A
- Zanella I
- Zanelli G
- Zara F
- Zara F
- Zarate R
- Zarate R
- Zborowski AC
- Zeberg H
- Zechner M
- Zechner M
- Zguro K
- Zhai R
- Zhang JE
- Zhang M
- Zhao JH
- Zhen J
- Zheng C
- Zheng T
- Zhou W
- Zhou W
- Zhu W
- Zitter L
- Zlatopolsky M
- Zoller H
- Zollner S
- Zongo O
- zu Bentrup FM
- Zucchi P
- Zwinderman AHK
- Zyndorf M
- Publication venue
- Publication date
- 01/01/2021
- Field of study
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3,4,5,6,7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease