Analysis of the Change in Dominant Phytoplankton Species in Unstratified Lake Oshima-Ohnuma Estimated by a Bottle Incubation Experiment

1996年5?7月に、渡島大沼において、優占植物プランクトンの細胞密度を測定し、さらにボトル培養実験によりそれらの成長速度を見積り、春から夏への植物プランクトン優占種変化に関わる要因を明らかにすることを試みた。4、5月にAsterionella gracillimaが優占種となったが、その成長速度は5月には比較的低く、その後、細胞密度が低下し、この主な原因は栄養塩の不足であることが示唆された。6月後半からMelosira gramulataの成長速度が増加し、優占種となった。M.gramulataは水深6mでも成長速度が高いことから、深層で生存できることと、湖が成層を形成しないことで再懸濁により有光層に存在できる状況が同種の成長に適していることが考えられた

Real-world evidence of the impact of obesity on residual teeth in the Japanese population : A cross-sectional study

Background:Tooth loss is associated with nutritional status and significantly affects quality of life, particularly in older individuals. To date, several studies reveal that a high BMI is associated with tooth loss. However, there is a lack of large-scale studies that examined the impact of obesity on residual teeth with respect to age and tooth positions.Objective:We assessed the impact of obesity on the number and position of residual teeth by age groups using large scale of Japanese database.Methods:This was a cross-sectional study of 706150 subjects that were included in the database that combined the data from health insurance claims and health check-up, those lacking information about BMI, HbA1c level, smoking status, and the number of residual teeth were excluded. Thus, a total of 233517 aged 20-74 years were included. Subjects were classified into 4 categories based on BMI, and the number of teeth was compared between age-groups. The percentage of subjects with residual teeth in each position was compared between groups with obesity (BMI ≥25.0 kg/m2) and non-obesity. Logistic regression analysis was performed to clarify whether obesity predicts having <24 teeth.Results:Higher BMI was associated with fewer teeth over 40s (P for trend <0.0001 when <70s). Obesity was associated with the reduction of residual teeth in the maxillary; specifically, the molars were affected over the age 30. Smoking status further affected tooth loss at positions that were not affected by obesity alone. After adjusting for age, sex, smoking status, and HbA1c ≥6.5%, obesity remained an independent predictive factor for having <24 teeth (ORs: 1.35, 95% CIs: 1.30-1.40).Conclusions:We found that an increase in BMI was associated with a decrease in the number of residual teeth from younger ages independently of smoking status and diabetes in the large scale of Japanese database

Dual supermassive black holes at close separation revealed by the Hyper Suprime-Cam Subaru Strategic Program

The unique combination of superb spatial resolution, wide-area coverage, and deep depth of the optical imaging from the Hyper Suprime-Cam (HSC) Subaru Strategic Program is utilized to search for dual quasar candidates. Using an automated image analysis routine on 34,476 known SDSS quasars, we identify those with two (or more) distinct optical point sources in HSC images covering 796 deg^2. We find 421 candidates out to a redshift of 4.5 of which one hundred or so are more likely after filtering out contaminating stars. Angular separations of 0.6 - 4.0" correspond to projected separations of 3 - 30 kpc, a range relatively unexplored for population studies of luminous dual quasars. Using Keck-I/LRIS and Gemini-N/NIFS, we spectroscopically confirm three dual quasar systems at z < 1, two of which are previously unknown out of eight observed, based on the presence of characteristic broad emission lines in each component, while highlighting that the continuum of one object in one of the pairs is reddened. In all cases, the [OIII]5007 emission lines have mild velocity offsets, thus the joint [OIII] line profile is not double-peaked. We find a dual quasar fraction of 0.26+/-0.18% and no evidence for evolution. A comparison with the Horizon-AGN simulation seems to support the case of no evolution in the dual quasar fraction when broadly matching the quasar selection. These results may indicate a scenario in which the frequency of the simultaneous triggering of luminous quasars is not as sensitive as expected to the cosmic evolution of the merger rate or gas content of galaxies.Comment: 11 pages; 12 figures; Accepted for publication in The Astrophysical Journa

Second nationwide surveillance of bacterial pathogens in patients with acute uncomplicated cystitis conducted by Japanese Surveillance Committee from 2015 to 2016: antimicrobial susceptibility of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus saprophyticus

The Japanese Surveillance Committee conducted a second nationwide surveillance of antimicrobial susceptibility patterns of uropathogens responsible for acute uncomplicated cystitis (AUC) in premenopausal patients aged 16–40 years old at 31 hospitals throughout Japan from March 2015 to February 2016. In this study, the susceptibility of causative bacteria (Escherichia coli, Klebsiella pneumoniae, Staphylococcus saprophyticus) for various antimicrobial agents was investigated by isolation and culturing of organisms obtained from urine samples. In total, 324 strains were isolated from 361 patients, including E. coli (n = 220, 67.9%), S. saprophyticus (n = 36, 11.1%), and K. pneumoniae (n = 7, 2.2%). The minimum inhibitory concentrations (MICs) of 20 antibacterial agents for these strains were determined according to the Clinical and Laboratory Standards Institute (CLSI) manual. At least 93% of the E. coli isolates showed susceptibility to fluoroquinolones and cephalosporins, whereas 100% of the S. saprophyticus isolates showed susceptibility to fluoroquinolones and aminoglycosides. The proportions of fluoroquinolone-resistant and extended-spectrum β-lactamase (ESBL)-producing E. coli strains were 6.4% (13/220) and 4.1% (9/220), respectively. The antimicrobial susceptibility of K. pneumoniae was retained during the surveillance period, while no multidrug-resistant strains were identified. In summary, antimicrobial susceptibility results of our second nationwide surveillance did not differ significantly from those of the first surveillance. Especially the numbers of fluoroquinolone-resistant and ESBL-producing E. coli strains were not increased in premenopausal patients with AUC in Japan

The Hyper Suprime-Cam SSP survey: Overview and survey design

Hyper Suprime-Cam (HSC) is a wide-field imaging camera on the prime focus of the 8.2-m Subaru telescope on the summit of Mauna Kea in Hawaii. A team of scientists from Japan, Taiwan, and Princeton University is using HSC to carry out a 300-night multi-band imaging survey of the high-latitude sky. The survey includes three layers: the Wide layer will cover 1400 deg2 in five broad bands (grizy), with a 5 σ point-source depth of r ≈ 26. The Deep layer covers a total of 26 deg2 in four fields, going roughly a magnitude fainter, while the UltraDeep layer goes almost a magnitude fainter still in two pointings of HSC (a total of 3.5 deg2). Here we describe the instrument, the science goals of the survey, and the survey strategy and data processing. This paper serves as an introduction to a special issue of the Publications of the Astronomical Society of Japan, which includes a large number of technical and scientific papers describing results from the early phases of this survey

Optical Spectroscopy of Dual Quasar Candidates from the Subaru HSC-SSP program

Tang, S., et al.We report on a spectroscopic program to search for dual quasars using Subaru Hyper Suprime-Cam (HSC) images of SDSS quasars, which represent an important stage during galaxy mergers. Using Subaru/FOCAS and Gemini-N/GMOS, we identify three new physically associated quasar pairs having projected separations less than 20 kpc, out of 26 observed candidates. These include the discovery of the highest-redshift (z = 3.1) quasar pair with a separation <10 kpc. Based on the sample acquired to date, the success rate of identifying physically associated dual quasars is 19% when excluding stars based on their HSC colors. Using the full sample of six spectroscopically confirmed dual quasars, including three previously published, we find that the black holes in these systems have black hole masses (M BH ∼ 108-9 M o˙), bolometric luminosities (log L bol ∼ 44.5-47.5 erg s-1) and Eddington ratios (0.01-0.3) similar to single SDSS quasars. We measure the stellar mass of their host galaxies based on 2D image decomposition of the five-band (grizy) optical emission and assess the mass relation between supermassive black holes (SMBHs) and their hosts. Dual SMBHs appear to have elevated masses relative to their host galaxies. Thus, mergers may not necessarily align such systems onto the local mass relation, as suggested by the Horizon-AGN simulation. This study suggests that dual luminous quasars are triggered by mergers prior to the final coalescence of the two SMBHs, resulting in early mass growth of the black holes relative to their host galaxies.Funding was contributed by the FIRST program from the Japanese Cabinet Office, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), the Japan Society for the Promotion of Science (JSPS), Japan Science and Technology Agency (JST), the Toray Science Foundation, NAOJ, Kavli IPMU, KEK, ASIAA, and Princeton Universit

Dual Supermassive Black Holes at Close Separation Revealed by the Hyper Suprime-Cam Subaru Strategic Program

Full author list: John D. Silverman, Shenli Tang, Khee-Gan Lee, Tilman Hartwig, Andy Goulding, Michael A. Strauss, Malte Schramm, Xuheng Ding, Rogemar A. Riffel, Seiji Fujimoto, Chiaki Hikage, Masatoshi Imanishi, Kazushi Iwasawa, Knud Jahnke, Issha Kayo, Nobunari Kashikawa, Toshihiro Kawaguchi, Kotaro Kohno, Wentao Luo, Yoshiki Matsuoka, Yuichi Matsuda, Tohru Nagao, Masamune Oguri, Yoshiaki Ono, Masafusa Onoue, Masami Ouchi, Kazuhiro Shimasaku, Hyewon Suh, Nao Suzuki, Yoshiaki Taniguchi, Yoshiki Toba, Yoshihiro Ueda, and Naoki YasudaThe unique combination of superb spatial resolution, wide-area coverage, and deep depth of the optical imaging from the Hyper Suprime-Cam (HSC) Subaru Strategic Program is utilized to search for dual quasar candidates. Using an automated image analysis routine on 34,476 known Sloan Digital Sky Survey quasars, we identify those with two (or more) distinct optical point sources in HSC images covering 796 deg2. We find 421 candidates out to a redshift of 4.5 of which one hundred or so are more likely after filtering out contaminating stars. Angular separations of 0.″6-4.″0 correspond to projected separations of 3-30 kpc, a range relatively unexplored for population studies of luminous dual quasars. Using Keck I/Low Resolution Imaging Spectrometer and Gemini-N/Near-Infrared Integral Field Spectrometer, we spectroscopically confirm three dual quasar systems at z < 1, two of which are previously unknown out of eight observed, based on the presence of characteristic broad emission lines in each component, while highlighting that the continuum of one object in one of the pairs is reddened. In all cases, the [O iii]λ5007 emission lines have mild velocity offsets, thus the joint [O iii] line profile is not double-peaked. We find a dual quasar fraction of 0.26 ± 0.18% and no evidence for evolution. A comparison with the Horizon-AGN simulation seems to support the case of no evolution in the dual quasar fraction when broadly matching the quasar selection. These results may indicate a scenario in which the frequency of the simultaneous triggering of luminous quasars is not as sensitive as expected to the cosmic evolution of the merger rate or gas content of galaxies.R. Morgan thanks the LSSTC Data Science Fellowship Program, which is funded by LSSTC, NSF Cybertraining Grant #1829740, the Brinson Foundation, and the Moore Foundation; his participation in the program has benefited this work. F. O.E. acknowledges support from the FONDECYT grant No. 1201223. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship Program under grant No. 1744555. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation. Funding for the DES Projects has been provided by the U.S. Department of Energy, the U.S. National Science Foundation, the Ministry of Science and Education of Spain, the Science and Technology Facilities Council of the United Kingdom, the Higher Education Funding Council for England, the National Center for Supercomputing Applications at the University of Illinois at Urbana-Champaign, the Kavli Institute of Cosmological Physics at the University of Chicago, the Center for Cosmology and AstroParticle Physics at The Ohio State University, the Mitchell Institute for Fundamental Physics and Astronomy at Texas A&M University, Financiadora de Estudos e Projetos, Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro, Conselho Nacional de Desenvolvimento Científico e Tecnológico and the Ministério da Ciência, Tecnologia e Inovação, the Deutsche Forschungsgemeinschaft, and the Collaborating Institutions in the Dark Energy Survey. The Collaborating Institutions are Argonne National Laboratory, the University of California at Santa Cruz, the University of Cambridge, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas-Madrid, the University of Chicago, University College London, the DES-Brazil Consortium, the University of Edinburgh, the Eidgenössische Technische Hochschule (ETH) Zürich, Fermi National Accelerator Laboratory, the University of Illinois at UrbanaChampaign, the Institut de Ciències de l’Espai (IEEC/CSIC), the Institut de Física d’Altes Energies, Lawrence Berkeley National Laboratory, the Ludwig-Maximilians Universität München and the associated Excellence Cluster Universe, the University of Michigan, NFS’s NOIRLab, the University of Nottingham, The Ohio State University, the University of Pennsylvania, the University of Portsmouth, SLAC National Accelerator Laboratory, Stanford University, the University of Sussex, Texas A&M University, and the OzDES Membership Consortium. The UCSC team is supported in part by NASA grant NNG17PX03C, NSF grant AST-1815935, the Gordon & Betty Moore Foundation, the Heising-Simons Foundation, and by fellowships from the David and Lucile Packard Foundation to R.J.F. Based in part on observations at Cerro Tololo InterAmerican Observatory at NSFʼs NOIRLab (NOIRLab Prop. ID 2012B-0001; PI: J. Frieman), which is managed by the Association of Universities for Research in Astronomy (AURA) under a cooperative agreement with the National Science Foundation. Based on observations obtained at the Southern Astrophysical Research (SOAR) telescope, which is a joint project of the Ministério da Ciência, Tecnologia, Inovação e Comunicações (MCTIC) da República Federativa do Brasil, the U.S. NSF’s NOIRLab, the University of North Carolina at Chapel Hill (UNC), and Michigan State University (MSU). The DES data management system is supported by the National Science Foundation under grant Nos. AST-1138766 and AST-1536171. The DES participants from Spanish institutions are partially supported by MICINN under grants ESP2017-89838, PGC2018-094773, PGC2018-102021, SEV2016-0588, SEV-2016-0597, and MDM-2015-0509, some of which include ERDF funds from the European Union. IFAE is partially funded by the CERCA program of the Generalitat de Catalunya. Research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Program (FP7/2007- 2013), including ERC grant agreements 240672, 291329, and 306478. We acknowledge support from the Brazilian Instituto Nacional de Ciência e Tecnologia (INCT) e-Universe (CNPq grant 465376/2014-2). This paper has gone through internal review by the DES collaboration. This manuscript has been authored by the Fermi Research Alliance, LLC under Contract No. DE-AC02- 07CH11359 with the U.S. Department of Energy, Office of Science, Office of High Energy Physics

Cardiovascular Malformations in CHARGE Syndrome with DiGeorge Phenotype: Two Case Reports

Both CHARGE syndrome and DiGeorge anomaly are frequently accompanied by cardiovascular malformations. Some specific cardiovascular malformations such as interrupted aortic arch type B and truncus arteriosus are frequently associated with 22q11.2 deletion syndrome, while conotruncal defects and atrioventricular septal defects are overrepresented in patients with CHARGE syndrome. CHD7 gene mutation is identified in approximately two-thirds of patients with CHARGE syndrome, and chromosomal microdeletion at 22q11.2 is found in more than 95% of patients with 22q11.2 deletion syndrome. CHARGE syndrome is occasionally accompanied by DiGeorge phenotype. We report two patients with dysmorphic features of both CHARGE syndrome and 22q11.2 deletion syndrome. Although both of the two cases did not have 22q11.2 deletion, they had typical dysmorphic features of 22q11.2 deletion syndrome including cardiovascular malformations such as interrupted aortic arch type B. They also had characteristic features of CHARGE syndrome including ear malformation, genital hypoplasia, limb malformation, and endocrinological disorders. CHD7 gene mutation was confirmed in one of the two cases. When a patient with cardiovascular malformations frequently associated with 22q11.2 deletion syndrome does not have 22q11.2 deletion, we suggest that associated malformations characteristic of CHARGE syndrome should be searched for