10 research outputs found
Interaction Effect of Social Isolation and High Dose Corticosteroid on Neurogenesis and Emotional Behavior
- Author
- Publication venue
- 'Frontiers Media SA'
- Publication date
- 01/01/2017
- Field of study
Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations.
- Author
- Aaronson Neil K
- Adank Muriel A
- Amor David
- Andrews Lesley
- Anjum Uruj
- Aprikian Armen
- Araujo Luis
- Ardern-Jones Audrey
- Arun Banu
- Ausems Margreet GEM
- Awatagiri Kasturi
- Balmana Judith
- Bambury Richard
- Bancroft Elizabeth
- Bancroft Elizabeth K
- Bangma Chris
- Bartlett Marion
- Barwell Julian
- Basevitch Alon
- Bealin Lisa
- Ben-Yehoshua Sagi Josefsberg
- Bermingham Nicola
- Birt Angela
- Bojeson Anders
- Boon Melanie
- Boshari Talia
- Bowman Michelle
- Brady Angela
- Brennhovd Bjorn
- Brewer Carole
- Brice Glen
- Bulman Barbara
- Burgess Lucy
- Burke Jo
- Buys Saundra
- Buys Saundra S
- Caanen BAH
- Capella Gabriel
- Carlsson Stefan
- Castro Elena
- Catto James
- Chamberlain Anthony
- Chapman Cyril
- Chen-Shtoyerman Rakefet
- Chong Michael
- Clowes Virginia
- Cogley Lyn
- Cole Trevor
- Compton Cecilia
- Conner Tom
- Cook Jackie
- Cooney Kathy
- Copakova Lucia
- Cornford Philip
- Costello Philandra
- Cruger Dorthe
- Cummings Carole
- Cybulski Cezary
- D'Mello Lucia
- Davidson Rosemarie
- Davis John W
- Dearing Audrey
- Dearnaley David
- Dechet Christopher
- Devlin Gemma
- Dias Alex
- Dineen Amy
- Domchek Susan
- Donaldson Alan
- Dorkins Huw
- Douglas Fiona
- Duffy Jessica
- Duncan Alexis
- Eccles Diana
- Eccles Diana M
- Eeles Rosalind
- Eeles Rosalind A
- Ekdahl Karl-Johan
- Ellery Natalie
- Esquena Salvador
- Evans D Gareth
- Evans David Gareth
- Evans Gareth
- Everest Sarah
- Eyfjord Jorunn
- Falconer Alison
- Farrell Michael
- Fisas David
- Fleming-Brown D
- Foster Christopher
- Foulkes William
- Friedman Eitan
- Frydenberg Mark
- Gadea Neus
- Gallagher David
- Gallagher Fergal
- Garcia Lynda
- Gay Simona
- George Angela
- Gerdes Anne-Marie
- Ghonge Sujata
- Giri Veda
- Gleeson Margaret
- Glover Wayne
- Goldgar David
- Goncalves Nuno
- Goodman Selina
- Gott Hannah
- Greenhalgh Lynn
- Griebsch C
- Griffiths Julie
- Grindedal Eli Marie
- Gronberg Henrik
- Gross Laura
- Gurasashvili Jana
- Halliday Dorothy
- Hamdy Freddie C
- Hammond Carrie
- Hanslien Eldbjorg
- Hanson Helen
- Harris Marion
- Hart Rachel
- Heaton Tricia
- Helderman-van den Enden A Paula TJM
- Helfand Brian T
- Henderson Alex
- Henrique Rui
- Hill Kathryn
- Hjalm-Eriksson Marie
- Hodgson Shirley
- Hoffman Jonathan
- Homfray Tessa
- Hook Nicole
- Howell Alice
- Howson Joanne
- Huber Camilla
- Hulick Peter
- Hunt Clare
- Ingram Stuart
- Islam Farah
- Jacobs Chris
- James Paul
- Jensen Thomas
- Jobson Irene
- Johannsson Oskar
- Johannsson Oskar Thor
- Kaemba Beckie
- Kast K
- Kaul Karen
- Kemp Zoe
- Khoo Vincent
- Kiemeney Bart
- Kiernan Ingrid
- Kiesel Vicki
- Kirk Judy
- Kockelbergh Roger
- Kohut Kelly
- Kosicka-Slawinska Monika
- Kote-Jarai Zsofia
- Kowtal Pradnya
- Krajc Mateja
- Kulkarni Anju
- Kumar Pardeep
- Lam Jimmy
- Langman Caroline
- Leibovici Dan
- Lilja Hans
- Liljegren Annelie
- Lindeman Geoffrey
- Longmuir Mark
- Lubinski Jan
- Maehle Lovise
- Magnani Tiziana
- Maia Sofia
- Male Alison
- Mascarenhas Lyon
- McBride Donna
- McGaughran Julie
- McGuire Michael
- McKinley Joanne
- Medvik Heidi
- Melville Athalie
- Melzer Ehud
- Mencias Mark
- Mercer Catherine
- Mikropoulos Christos
- Millard Richard
- Miller Cathy
- Millner Alan
- Mitchell Gillian
- Mitra Anita
- Moller Pal
- Mom Jaswant
- Mora Josefina
- Morote Juan
- Morton Catherine
- Moss Cathryn
- Moynihan Clare
- Mulgund Gouri
- Murphy Declan
- Murphy Morgan
- Murthy Vedang
- Myhill Kathryn
- Mzazi Shumikazi
- Nadolski Maria
- Nevitt Louise
- Newcombe Barbara
- Newlin Anna
- Nicholls Cassandra
- Nicolai Nicola
- Nogueira Pedro
- O'Connell Shona
- Obeid Elias
- Offman Judith
- Ogden Chris
- Okoth Linda
- Oldenburg Rogier A
- Oliveira Jorge
- Ong Kai-Ren
- Oosterwijk Jan C
- Osther Palle
- Pachter Nicholas
- Paez Edgar
- Page Elizabeth
- Page Elizabeth C
- Patel Manish
- Patel Nafisa
- Paterson Joan
- Patterson Briony
- Pearce Allison
- Peixoto Ana
- Petelin Lara
- Pichert Gabriella
- Pope Jennifer
- Pope Jenny
- Poplawski Nicola
- Potter Alison
- Poultney Una
- Powers Jacquelyn
- Radice Paolo
- Ramon y Cajal Teresa
- Randhawa Kashmir
- Rees Katie
- Reinholtz Cherylin
- Rennert Gad
- Renton Caroline
- Rhiem Kerstin
- Richardson Kate
- Ringleberg Janneke
- Rosario Derek
- Rosario Derek J
- Rose Sarah
- Rothwell Jeanette
- Rubinstein Wendy S
- Ruijs Marielle WG
- Rustgi Neil
- Salinas Monica
- Sarin Rajiv
- Sattar Ayisha
- Saya Sibel
- Schmutzler Rita
- Schofield Lyn
- Scott Rodney
- Searle Anne
- Seixas Manuela
- Selkirk Christina Hutten
- Shackleton Kylie
- Shanley Sue
- Shaw Adam
- Shevrin Daniel
- Sidat Zahirah
- Side Lucy
- Siguake Kas
- Simon Kate
- Skytte Anne-Bine
- Smyth Courtney
- Snape Katie
- Souto Joao Paulo
- Spigelman Allan
- Stapleton Alan
- Stayner Barbara
- Stefansdottir Vigdis
- Stephenson Robert
- Stoffel Elena
- Stricker Phillip
- Strom Sara
- Suri Mohnish
- Susman Rachel
- Suthers Graeme
- Sutton Vivienne
- Swindle Peter
- Tan Hui Meng
- Taylor Amy
- Taylor Louise
- Taylor Natalie
- Teixeira Manuel
- Teo Soo Hwang
- Thomas Sarah
- Thompson Alan
- Thong Meow Keong
- Tidey Lizzie
- Tischkowitz Marc
- Tomkins Sue
- Tondering Majbritt Kure
- Torokwa Audrey
- Townshend Sharron
- Treherne Katy
- Tricker Karen
- Tripathi Vishakha
- Tucker Katherine
- Umez-Eronini Nkem
- Valdagni Riccardo
- Van As Nicholas
- van Asperen Christi
- van der Luijt Rob B
- van Os Theo
- van Zelst-Stams Wendy
- Vasen Hans
- Venne Vickie
- Vogel Kristen
- Vrecar Alenka
- Walker Lisa
- Ward Robyn
- Watson Michelle
- Watt Cathy
- Weiss Shelly
- Weissman Scott
- Wiggins Jennifer
- Wihler Petra
- Williams Rachel
- Wise Gillian
- Wokolorczyk Dominika
- Woodhouse Christopher
- Yamamura Yuko
- Yesildag Pembe
- Yoon Sook-Yee
- Zgajnar Janez
- Publication venue
- BJU Int
- Publication date
- 26/05/2018
- Field of study
OBJECTIVES: To report the baseline results of a longitudinal psychosocial study that forms part of the IMPACT study, a multi-national investigation of targeted prostate cancer (PCa) screening among men with a known pathogenic germline mutation in the BRCA1 or BRCA2 genes. PARTICPANTS AND METHODS: Men enrolled in the IMPACT study were invited to complete a questionnaire at collaborating sites prior to each annual screening visit. The questionnaire included sociodemographic characteristics and the following measures: the Hospital Anxiety and Depression Scale (HADS), Impact of Event Scale (IES), 36-item short-form health survey (SF-36), Memorial Anxiety Scale for Prostate Cancer, Cancer Worry Scale-Revised, risk perception and knowledge. The results of the baseline questionnaire are presented. RESULTS: A total of 432 men completed questionnaires: 98 and 160 had mutations in BRCA1 and BRCA2 genes, respectively, and 174 were controls (familial mutation negative). Participants' perception of PCa risk was influenced by genetic status. Knowledge levels were high and unrelated to genetic status. Mean scores for the HADS and SF-36 were within reported general population norms and mean IES scores were within normal range. IES mean intrusion and avoidance scores were significantly higher in BRCA1/BRCA2 carriers than in controls and were higher in men with increased PCa risk perception. At the multivariate level, risk perception contributed more significantly to variance in IES scores than genetic status. CONCLUSION: This is the first study to report the psychosocial profile of men with BRCA1/BRCA2 mutations undergoing PCa screening. No clinically concerning levels of general or cancer-specific distress or poor quality of life were detected in the cohort as a whole. A small subset of participants reported higher levels of distress, suggesting the need for healthcare professionals offering PCa screening to identify these risk factors and offer additional information and support to men seeking PCa screening
WHO global research priorities for antimicrobial resistance in human health
- Author
- Aanensen David
- Al-Hasan Majdi
- Al-Maani Amal Saif
- Al-Salman Jameela
- Alanio Alexandre
- Alastruey-Izquierdo Ana
- Alemayehu Tinsae
- Allegaert Karel
- Allegranzi Benedetta
- Alshukairi Abeer Nizar
- Amir Afreenish
- Applegate Tanya
- Araj George F
- Ashiru-Oredope Diane
- Ashley Elizabeth A
- Babin François-Xavier
- Bachmann Laura H
- Bachmann Till
- Baker Kate Susan
- Balasegaram Manica
- Balkhy Hanan H
- Bamford Colleen
- Baquero Fernando
- Barcelona Laura Isabel
- Bassat Quique
- Bassetti Matteo
- Basu Sulagna
- Beardsley Justin
- Berkley James A
- Bertagnolio Silvia
- Bhatnagar Anuj K
- Bielicki Julia
- Bines Julie
- Bongomin Felix
- Bonomo Robert A
- Bradley John S
- Bradshaw Catriona
- Brett Ana
- Brink Adrian
- Brown Colin
- Brown Jeremy
- Buising Kirsty
- Burzo Stefano
- Carson Carolee
- Carvalho Anna Cristina
- Cassini Alessandro
- Castagnola Elio
- Cavaleri Marco
- Cecchini Michele
- Centner Chad M
- Chabala Chishala
- Chaillon Antoine
- Chaisson Richard E
- Chakrabarti Arunaloke
- Chandler Clare
- Chandy Sujith John
- Charani Esmita
- Chen Lisa
- Chiara Francesca
- Chowdhary Anuradha
- Chua Arlene
- Chuki Pem
- Chun Doo Ryeon
- Churchyard Gavin
- Cirillo Daniela
- Clack Lauren
- Coffin Susan E
- Cohn Jennifer
- Cole Michelle
- Conly John
- Cooper Ben
- Corso Alejandra
- Cosgrove Sara E
- Cox Helen
- Daley Charles L
- Darboe Saffiatou
- Darton Tom
- Davies Gerry
- de Egea Viviana
- Dedeić-Ljubović Amela
- Deeves Miranda
- Denkinger Claudia
- Dillon Jo-Anne R
- Dobreva Zlatina
- Donà Daniele
- Dramowski Angela
- Eley Brian
- Essack Sabiha Y
- Farida Helmia
- Farooqi Joveria
- Feasey Nicholas
- Ferreyra Cecilia
- Fifer Helen
- Finlayson Heather
- Frick Mike
- Gales Ana Cristina
- Galli Luisa
- Gandra Sumanth
- Gebreselassie Nebiat
- Gerber Jeffrey S
- Giske Christian
- Gordon Bruce
- Govender Nelesh
- Guessennd Nathalie
- Guindo Ibrehima
- Gurbanova Elmira
- Gwee Amanda
- Hagen Ferry
- Hamers Raph L
- Harbarth Stephan
- Hasso-Agopsowicz Mateusz
- Haze John
- Heim Jutta
- Hendriksen Rene
- Heyderman Robert Simon
- Holt Kathryn Elizabeth
- Hook Edward W
- Hope William
- Hopkins Heidi
- Hughes Gwenda
- Huttner Benedikt D
- Hönigl Martin
- Ismail Ghada
- Issack Mohammad Iqbal
- Ivanovska Verica
- Jacobs Jan
- Jasovský Dušan
- Jehan Fyeza
- Jones Makoto
- Joshi Mohan P
- Kapil Arti
- Kariuki Samuel
- Karkey Abhilasha
- Kearns Gregory L
- Keddy Karen Helena
- Khanna Nina
- Kitamura Akiko
- Kolho Kaija-Leena
- Kontoyiannis Dimitrios P
- Kothari Kavita U
- Kotwani Anita
- Kozlov Roman S
- Kranzer Katharina
- Kularatne Ranmini
- Lahra Monica M
- Langford Bradley J
- Laniado-Laborin Rafael
- Larsson Joakim
- Lass-Flörl Cornelia
- Le Doare Kirsty
- Lee Hyukmin
- Lessa Fernanda
- Levin Anna S
- Limmathurotsakul Direk
- Lincopan Nilton
- Lo Vecchio Andrea
- Lodha Rakesh
- Loeb Mark
- Longtin Yves
- Lye David Chien
- Lyra Tavares De Melo Flávio Augusto
- Mahmud Asif Mujtaba
- Manaia Célia
- Manderson Lenore
- Mareković Ivana
- Marimuthu Kalisvar
- Martin Irene
- Mashe Tapfumanei
- Mei Zeng
- Meis Jacques F
- Mendelson Marc
- Miranda Angelica Espinosa
- Moore David
- Morel Chantal
- Moremi Nyambura
- Moro Maria Luisa
- Moscoso Martin Yagui
- Moussy Francis
- Mshana Stephen
- Mueller Arno
- Ndow Francis J
- Nicol Mark
- Nunn Andrew
- Obaro Stephen
- Obiero Christina W
- Okeke Iruka N
- Okomo Uduak
- Okwor Tochi J
- Oladele Rita
- Olaru Ioana Diana
- Omar Shaheed Vally
- Omulo Sylvia
- Ondoa Pascale
- Ortellado de Canese Juana Medarda
- Ostrosky-Zeichner Luis
- Padoveze Maria Clara
- Pai Madhukar
- Park Benjamin
- Parkhill Julian
- Parry Christopher M
- Pearson Antonieta Jimenez
- Peeling Rosanna
- Perovic Olga
- Pettigrew Melinda M
- Principi Nicola
- Pulcini Céline
- Puspandari Nelly
- Rawson Timothy
- Reddy Denasha Lavanya
- Reddy Kessendri
- Redner Paulo
- Roberta Esposito Susanna Maria
- Rodríguez Tudela Juan Luis
- Rodríguez-Baño Jesús
- Roilides Emmanuel
- Rollier Christine
- Rollock Leslie
- Ronat Jean-Baptiste
- Ruppe Etienne
- Sadarangani Manish
- Salisbury David
- Salou Mounerou
- Samison Luc Hervé
- Sanguinetti Maurizio
- Sartelli Massimo
- Sati Hatim
- Schellack Natalie
- Schouten Jeroen
- Schwaber Mitchell J
- Seni Jeremiah
- Senok Abiola
- Shafer William M
- Shakoor Sadia
- Sheppard Donald
- Shin Jong-Hee
- Sia Sonia
- Sievert Dawn
- Singh Ishwar
- Singla Rupak
- Skov Robert Leo
- Sobreira Vieira Peixe Luísa Maria
- Soge Olusegun O
- Sprute Rosanne
- Srinivasan Arjun
- Srinivasan Subasree
- Sundsfjord Arnfinn
- Tacconelli Evelina
- Tahseen Sabira
- Tangcharoensathien Viroj
- Thursky Karin
- Thwaites Guy
- Tigulini de Souza Peral Renata
- Tong Deborah
- Tootla Hafsah Deepa
- Tsioutis Constantinos
- Turner Katy M
- Turner Paul
- Tängdén Thomas
- van de Sande Wendy WJ
- van den Hof Susan
- van Doorn Rogier
- Van Katwyk Susan Rogers
- Veeraraghavan Balaji
- Verweij Paul
- Villalobos Marlen Arce
- Vásquez Grey Benoit
- Wahyuningsih Retno
- Wang Hui
- Warris Adilia
- Weezenbeek Kitty Van
- Weinstock Hillard
- Wesangula Evelyn
- Whiley David
- White Peter J
- Wi Teodora
- Williams Phoebe
- Xiao Yonghong
- Yang Hsu Li
- Yoshida Sachiyo
- Yu Yunsong
- Zignol Matteo
- Årdal Christine
- Żabicka Dorota
- Publication venue
- Elsevier BV
- Publication date
- 12/08/2024
- Field of study
The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, and treatment of antimicrobial-resistant infections, in addition to addressing the overarching knowledge gaps in AMR epidemiology, burden and drivers, policies and regulations, and awareness and education. The research priorities were identified through a multistage process, starting with a comprehensive scoping review of knowledge gaps, with expert inputs gathered through a survey and open call. The priority setting involved a rigorous modified Child Health and Nutrition Research Initiative approach, ensuring global representation and applicability of the findings. The ultimate goal of this research agenda is to encourage research and investment in the generation of evidence to better understand AMR dynamics and facilitate policy translation for reducing the burden and consequences of AMR
Boredom begets boredom: An experience sampling study on the impact of teacher boredom on student boredom and motivation
- Author
- Publication venue
- 'Wiley'
- Publication date
- 01/06/2020
- Field of study
Interaction Effect of Social Isolation and High Dose Corticosteroid on Neurogenesis and Emotional Behavior
- Author
- Abramets
- Alan H. L. Chan
- Axelson
- Beery
- Benson W.-M. Lau
- Brown
- Brummelte
- Castro
- Cheung
- Cinini
- Dalinda I. Sánchez-Vidaña
- Djordjevic
- Drew
- Famitafreshi
- Fenton
- File
- Fone
- Gould
- Heidbreder
- Imayoshi
- Jackie N.-M. Chan
- Jada C.-D. Lee
- Katy K. Y. Hui
- Lau
- Lavergne
- Leuner
- Lieberwirth
- Lieberwirth
- Liu
- Lukkes
- Marks
- O’Connor
- Petrik
- Po
- Porsolt
- Powell
- Revest
- Riise
- Ruan
- Ruscio
- Sahay
- Santarelli
- Sarah
- Sharp
- Shirley P.-C. Ngai
- Shoji
- Skórzewska
- Smith
- Snyder
- Surget
- Sylvia S. P. Lee
- Tabachnick
- Tanaś
- Taylor
- Timothy K.-H. Fung
- Wang
- Publication venue
- 'Frontiers Media SA'
- Publication date
- Field of study
Henkilöstön vaihtuvuus ja siihen liittyvät tekijät telemarkkinointialalla : case: Gainer Oy
- Author
- Aaronson Neil
- Adank Muriel A.
- Amor David J.
- Andrews Lesley
- Appelman Zvi
- Aprikian Armen
- Araujo Luis
- Ardern-Jones Audrey
- Arun Banu
- Assel Melissa
- Ausems Margreet G.
- Awatagiri Kasturi
- Axcrona Karol
- Axcrona Ulrika
- Bacic Sonya
- Balmana Judith
- Bambury Richard
- Bancroft Elizabeth K.
- Bangma Chris
- Bartlett Marion
- Barwell Julian
- Ben-Yehoshua Sagi Josefsberg
- Birt Angela
- Blanco Ignacio
- Bojesen Anders
- Bojeson Anders
- Boon Melanie
- Borley Nigel
- Bowman Michelle
- Brady Angela F.
- Brendler Charles
- Brennhovd Bjorn
- Brewer Carole
- Brice Glen
- Bulman Barbara
- Burgess Lucy
- Burke Jo
- Buys Saundra
- Capella Gabriel
- Carlsson Stefan
- Castro Elena
- Catto James
- Chapman Cyril
- Chen-Shtoyerman Rakefet
- Chong Michael
- Cleeve Laurence
- Clowes Virginia E.
- Cogley Lyn
- Cole Trevor
- Compton Cecilia
- Conner Tom
- Cook Jackie
- Copakova Lucia
- Cornford Philip
- Costello Philandra
- Cremers Ruben
- Cruger Dorthe
- Cummings Carole
- Cybulski Cezary
- Davidson Rosemarie
- Davis John W.
- Dearnaley David
- Dechet Christopher
- Devlin Gemma
- Doherty Rebecca
- Domchek Susan
- Donaldson Alan
- Dorkins Huw
- Douglas Fiona
- Drew Kate
- Duffy Jessica
- Duncan Alexis
- Eccles Diana
- Eeles Rosalind A.
- Ekdahl Karl-Johan
- Ellery Natalie
- Evans D. Gareth
- Everest Sarah
- Eyfjord Jorunn
- Falconer Alison
- Farrell Michael
- Fiddike Kerstin
- Fisas David
- Fleming-Brown D.
- Foster Christopher S.
- Foulkes William D.
- Friedman Eitan
- Frydenberg Mark
- Gadea Neus
- Gallagher David
- Gallagher Fergal
- Garcia Lynda
- Gerdes Anne-Marie
- Ghonge Sujata
- Giri Veda N.
- Gleeson Margaret
- Goh Chee
- Goldgar David
- Goncalves Nuno
- Goodman Selina
- Greenhalgh Lynn
- Griffiths Julie
- Gronberg Henrik
- Gross Laura
- Halliday Dorothy
- Hamdy Freddie C.
- Hammond Carrie
- Hanslien Eldbjorg
- Hanson Helen
- Harris Marion
- Heaton Tricia
- Helderman-van den Enden Apollonia T.
- Helfand Brian
- Henderson Alex
- Henrique Rui
- Hill Kathryn
- Hjalm-Eriksson Marie
- Hodgson Shirley
- Hoffman Jonathan
- Homfray Tessa
- Howson Joanne
- Hulick Peter J.
- Hunt Clare
- Ingram Stuart
- Izatt Louise
- Jacobs Chris
- Jobson Irene
- Johannsson Oskar
- Kaemba Beckie
- Kaul Karen
- Keating Diana
- Khoo Vincent
- Kiemeney Bart
- Kiemeney Lambertus A.
- Kiesel Vicki
- Killick Emma
- Kirk Judy
- Kockelbergh Roger
- Kohut Kelly
- Kosicka-Slawinska Monika
- Kote-Jarai Zsofia
- Kowtal Pradnya
- Krajc Mateja
- Kumar Pardeep
- Lam Jimmy
- Langman Caroline
- Lilja Hans
- Liljegren Annelie
- Lindeman Geoffrey J.
- Longmuir Mark
- Lubinski Jan
- Luedtke-Heckenkamp Kerstin
- Maehle Lovise
- Magnani Tiziana
- Maia Sofia
- Male Alison
- Martin Sue
- McBride Donna
- McGaughran Julie
- McGrath John
- McGuire Michael
- McKinley Joanne
- Medvik Heidi
- Melia Jane
- Melville Athalie
- Meng Tan Hui
- Mercer Catherine
- Millard Richard
- Miller Cathy
- Mitchell Gillian
- Mitra Anita V.
- Moller Pal
- Mom Jaswant
- Moriel Evyatar
- Morote Juan
- Moss Sue
- Moynihan Clare
- Mulgund Gouri
- Murphy Declan
- Murphy Morgan
- Murthy Vedang
- Nadolski Maria
- Nevitt Louise
- Newcombe Barbara
- Newlin Anna
- Nicolai Nicola
- Nissani Rachel
- Nogueira Pedro
- O'Connell Shona
- Ochsendorf Nicole
- Ogden Chris
- Oldenburg Rogier
- Oliveira Jorge
- Ong Kai-ren
- Oosterwijk Jan C.
- Osther Palle
- Pachter Nicholas
- Paez Edgar
- Page Elizabeth C.
- Patcher Nicholas
- Patel Manish
- Patel Nafisa
- Paterson Joan
- Patterson Briony
- Peixoto Ana
- Petelin Lara
- Pichert Gabriella
- Pope Jenny
- Potter Alison
- Poultney Una
- Powers Jacquelyn
- Pratt Sarah
- Radice Paolo
- Ramon y Cajal Teresa
- Randhawa Kashmir
- Rees Katie
- Rennert Gad
- Renton Caroline
- Rhiem Kerstin
- Ringelberg Janneke
- Roberts Gillian
- Rosario Derek J.
- Rothwell Jeanette
- Rubinstein Wendy
- Ruijs Marielle
- Salinas Monica
- Sarin Rajiv
- Sattar Ayisha
- Saya Sibel
- Schmutzler Rita
- Schofield Lyn
- Scott Rodney
- Searle Anne
- Seixas Manuela
- Selkirk Christina
- Shackleton Kylie
- Shanley Susan
- Shevrin Daniel
- Sidat Zahirah
- Side Lucy
- Siguake Kas
- Simon Kate
- Sjoberg Daniel
- Skytte Anne-Bine
- Smyth Courtney
- Souto Joao Paulo
- Spigelman Allan
- Stapleton Alan
- Stayner Barbara
- Stefansdottir Vigdis
- Stephenson Robert
- Stricker Phillip
- Strom Sara
- Suri Mohnish
- Susman Rachel
- Suthers Graeme
- Sutton Vivienne
- Swindle Peter
- Taherian Nassim
- Taylor Amy
- Taylor Louise
- Taylor Natalie
- Teixeira Manuel R.
- Teo Soo-Hwang
- Thompson Alan
- Thong Meow Keong
- Tidey Lizzie
- Tischkowitz Marc
- Tomkins Sue
- Townshend Sharron
- Treherne Katy
- Tucker Katherine
- Tucker Kathy
- Umez-Eronini Nkem
- Valdagni Riccardo
- Van As Nicholas
- van Asperen Christi
- Van der Luijt Rob B.
- van Os Theo
- van Zelst-Stams Wendy A.
- Vasen Hans
- Venne Vickie
- Verhaegh Gerald
- Vickers Andrew
- Vogel Kristen
- Vrecar Alenka
- Walker Lisa
- Ward Robyn
- Watt Cathy
- Weiss Shelly
- Weissman Scott
- Weston Michelle
- Wiggins Jennifer
- Williams Rachel
- Wilson Penny
- Wokolorczyk Dominika
- Woodhouse Christopher
- Woodward Anthony
- Yamamura Yuko
- Yoon Sook-Yee
- Zgajnar Janez
- Publication venue
- Lahden ammattikorkeakoulu
- Publication date
- 01/01/2014
- Field of study
Tämä opinnäytetyö toteutettiin toimeksiantosopimuksena Gainer Oy:lle, joka on toiminut telemarkkinoinnin alalla jo vuodesta 1984. Opinnäytetyön tutkimusstrategiaksi valittiin case study eli tapaustutkimus. Käytimme tutkimusmenetelmänä kvalitatiivista eli laadullista tutkimusta.
Tavoitteenamme oli tutkia ja selvittää henkilöstön vaihtuvuutta ja siihen liittyviä tekijöitä alalla, jossa henkilöstön vaihtuvuus koetaan ongelmaksi.
Teoriaosuudessa käsittelemme teoreettisen viitekehyksen liittyen työnantajan keinoihin vaikuttaa työntekijän sitouttamiseen. Tämä on jaettu kahteen osa-alueeseen, jotka ovat rekrytointi sekä työhyvinvointi ja osaamisen kehittäminen.
Empiirisessä osiossa päädyimme käyttämään puolistrukturoitua teemahaastattelua, joka toteutettiin suurimmaksi osaksi puhelimitse sekä muutama haastattelu tehtiin kasvotusten. Teemahaastattelu valikoitui parhaimmaksi menetelmäksi johtuen aiheen moniulotteisuudesta. Avoimella haastattelulla emme olisi välttämättä saaneet merkittävää tietoa samassa mittakaavassa kuin puolistrukturoidulla mallilla.
Opinnäytetyön tuloksena päädyimme esittämään toimeksiantajalle muutamia kehitysehdotuksia. Haastatteluista johdetuilla päätelmillä saatettaisiin parantaa rekrytoinnin onnistumista, joka osaltaan parantaa kannattavuutta niin tuloksellisesti, kuin henkilöstön resurssejakin säästäen. Kehitysehdotuksia muodostui myös muihin osa-alueisiin liittyen. Näillä on myös vaikutusta henkilöstön yleiseen työhyvinvointiin ja työssä jaksamiseen.This thesis was carried out as a commission agreement for Gainer Oy, which has operated in the field of telemarketing since 1984. Our study was carried out as a case study using qualitative approach as our research method. Our objective was to study personnel turnover and matters relating to it in a field where personnel turnover is seen as a problem.
In the theoretical section of the study we deal with the theoretical frame of reference related to the employer's means to influence employee engagement. This is divided into two sections that are recruiting, and occupational health and development of skills.
In the empirical part of our study, we ended up using half-structured theme interviews, which were mainly carried out by telephone. A few interviews were carried out face-to-face. Theme interview was selected to be the best method because of the multidimensionality of the subject. By using open interviews, we would not necessarily have received as much significant information as by using the half-structured model.
As a result of our study, we presented a few development proposals for our client/commissioner. The conclusions drawn from the interviews may lead to more successful recruiting, which in turn improves viability both in terms of productivity and by saving the resources of the personnel. There were also other development proposals concerning other areas. The results of the study may also help to improve the general well-being at work and coping with one’s workload
Recommended from our members
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, MD, USA. 9-13 November 2016
- Author
- Aarts Craig
- Abdallah Rehab
- Abdul-Alim Siddiq
- Abolhalaj Milad
- Abtin Fereidoun
- Acheson Anupama
- Acquavella Nicolas
- Adams Gregory P.
- Adams Katherine
- Adams Sharon
- Adamus Tomasz
- Adekandi Madhukara
- Adurthi Sreenivas
- Adusumilli Prasad S.
- Aeffner Famke
- Afentoulis Michael
- Ager Casey
- Aggouraki Despoina
- Agrawal Rajendra
- Agrawal Sudhir
- Agrawal Swati
- Ahlers Christoph Matthias
- Ahmed Nabil
- Ahn Myung Ju
- Ahr Katya
- Ai Midan
- Aiba Rachida-Siham Bel
- Aisner Joseph
- Albertini Mark R.
- Albiges Laurence
- Albright Andrew
- Algazi Alain
- Ali Siraj
- Alicea Candido
- Allen Natalie
- Allersdorfer Andrea
- Alva Ajjai
- Amado Rafael
- Amaria Rodabe
- Ameratunga Malaka
- Amin Asim
- Amor Amira Ben
- Amrhein John
- Anagnostou Valsamo
- Andersen Rikke
- André Thierry
- Andtbacka Robert H. I.
- Angela Omilian
- Angell Helen K.
- Annels Nicola
- Annunziata Christina M.
- Ansa-Addo Ephraim A
- Ansari Tameem
- Antilla Marjukka
- Antonarakis Emmanuel S.
- Aoki Rhonda
- Armand Philippe
- Armstrong Adam
- Arora Kshitij
- Arreaza Gladys
- Ascierto Paolo A.
- Ashworth-Sharpe Julia
- Askmyr David
- Asmellash Senait
- Assadipour Yasmine
- Assenmacher Mario
- Athelogou Maria
- Atkins Michael B.
- Attaf Meriem
- Au Gough
- Au-Young Janice
- Avery Kendra N.
- Ayers Mark
- Azimi Vahid
- Aznar M. Angela
- Backert Linus
- Backes Floor J.
- Bagg Eleanor A. L.
- Bahjat Keith
- Bajorin Dean
- Bakker Lex
- Balakumaran Arun
- Ballesteros-Merino Carmen
- Bander Neil
- Bang Yung-Jue
- Bannerji Rajat
- Baratelli Felicita E.
- Barbee Susannah D.
- Barlesi Fabrice
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- Bauer Todd M.
- Bauer Todd W.
- Baughman Jan E.
- Bayle J. Henri
- Baylin Stephen
- Beechem Joseph
- Beeson Craig
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- Bellovin David I.
- Beltran Nancy
- Bendell Johanna
- Bender James
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- Bennett Mark K.
- Bergamaschi Cristina
- Berger Frank
- Berger Sven
- Bergeron Derek
- Berglund Anders
- Berglund Sofia
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- Bernett Matthew J.
- Bernstein Donna
- Bessell Catherine A.
- Betts Gareth
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- Bhardwaj Rukmini
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- Bhaumik Srabani
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- Bielamowicz Kevin
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- Billingsley James M.
- Binder-Scholl Gwendolyn
- Binnig Gerd
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- Borges Luis
- Borkar Rohan N.
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- Bosch Marnix
- Bose Nandita
- Bossen Bolette
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- Boussiotis Vassiliki A.
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- Brevard Julie
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- Cao Alexander
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- Caux Christophe
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- Celis Esteban
- Cerkovnik Logan
- Cervera-Carrascón Víctor
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- Chagin Karen
- Chakraborty Paramita
- Champagne Monique
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- Chaudhri Apoorvi
- Cheever Martin
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- Chen Lawrence
- Chen Lieping
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- Chen Xiufen
- Cheng Jonathan
- Cheng Zhi-jie Jey
- Chikina Maria
- Chin Renee
- Chinnasamy Harshini
- Chlosta Sabine
- Choi Minsig
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- Christian Beth
- Chu Liz
- Chu Seung
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- Clark Joseph I.
- Clayburgh Daniel R.
- Clement Amanda
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- Cohen Zvi
- Colevas A Dimitrios
- Collins Jennifer
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- Conrad Valerie
- Conroy Jeff
- Copeland Larry
- Copploa Domenico
- Cordes Lisa
- Cornfeld Mark
- Cortina Luis
- Coussens Lisa M.
- Couto Joseph
- Coveler Andrew L.
- Crabill George
- Cristescu Razvan
- Crocker Andrea
- Cui Weiguo
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- Cumberbatch Kerwin
- Curran Michael
- Curti Brendan
- Dadey Rebekah
- Daenthanasanmak Anusara
- Dai Zhimin
- Damare Sherri
- Dammassa Ernesta
- Danaher Patrick
- Danforth David
- Daud Adil
- Davar Diwakar
- Davenport Anna
- David Larry
- Davies Bronwyn
- Davies Michael A.
- Davis Tom
- De Bono Johann
- De Macedo Mariana Petaccia
- de Oliveira Moacyr Ribeiro
- De Santis Maria
- de Wit Ronald
- Deacon Donna H.
- Deeds Michael
- Del Pilar Estevez Diz Maria
- Delcommenne Marc
- Delgoffe Greg M.
- Delismon Judy
- Denisova Galina
- Dennis Lucas
- Deol Abhinav
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- Deshpande Vikram
- Desjarlais John
- Deveraux Quinn
- DeVito Anna Marie
- Devlin Sean
- Dey Chaitali
- Dhudashia Amit
- di Pietro Alessandra
- Diab Adi
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- Dietz Allan B.
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- Dobson Jason R.
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- Donda Alena
- Donia Marco
- Donovan Michael Joseph
- doo Chang Young
- Doody Jacqueline
- Dotti Gianpietro
- Dougherty Janna
- Downing Sean
- Dragnev Konstanin
- Drake Charles G.
- Dranoff Glenn
- Draper Lindsey M.
- Drechsel Katharina
- Dreicer Robert
- Dubay Christopher
- Dubey Aparajita
- Dubinett Steven M.
- Dubois Sigrid
- Duhen Rebekka
- Duhen Thomas
- Dummer Reinhard
- Dunaway Dwayne
- Duncan Brynn
- Dundr Pavel
- Duong MyLinh
- Dutour Aurélie
- Dyson Gregory
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- El Rassi Edward
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- Enblad Gunilla
- Erdag Gulsun
- Ernstoff Marc S.
- Essand Magnus
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- Evans Kathy
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- Fakhrejahani Farhad
- Falchook Gerald
- Fan Aaron
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- Fang Victoria
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- Fardis Maria
- Faries Mark
- Faroudi Mustapha
- Farrell Michael
- Fast Loren
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- Feldman Steven A.
- Feng Dai
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- Fraser Kathryn
- Frayssinet Véronique
- Freeman Gordon J.
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- Gangadhar Tara C.
- Gangxiong Huang
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- Geib James
- Geiss Gary
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- Georgoulias V.
- Gerken Claudia
- Gerry Andrew
- Gershan Jill
- Gershenson Zack
- Ghaffari Mahsa
- Ghori Razi
- Gianani Roberto
- Gilden Julia
- Gill Saar
- Gillies Stephen D.
- Giralt Sergio
- Giri Rajanish
- Gitlitz Barbara
- Giver Cynthia R.
- Glenn Sean
- Glitza Isabella
- Glod John
- Gnad-Vogt Ulrike
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- Gojo Ivana
- Gokuldass Aishwarya
- Goldinger Simone
- Goldman Jonathan W.
- Goldschmidt Hartmut
- Goldstein Joel
- Gonzalez Denise
- Gonzalez Iliana
- Gonzalez Ricardo
- Gorden Keith
- Gormley Michael
- Gottschalk Stephen
- Govindappa Nagaraja
- Gowda Nagaraj
- Gowda Nagesh
- Graff Jeremy
- Grailer Jamison
- Graziano Robert F.
- Green Daniel S.
- Gregory Gareth
- Greiff Lennart
- Grilley-Olson Juneko E.
- Grimaldi Antonio
- Grose Mark
- Gross Matt
- Grossenbacher Steven
- Grossenbacher Steven K.
- Grupp Stephan
- Gschwendt Juergen
- Gu Xuemin
- Guan Wei
- Guindani Michele
- Gulley James
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- Gunset Gertrude
- Gustafson Michael P.
- Guyre Cheryl A.
- Haanen John B.
- Habensus Iva
- Hackl Hubert
- Hacohen Nir
- Hadrup Sine Reker
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- Hahn Noah M.
- Halaban Ruth
- Hall MacLean
- Halmos Balazs
- Hamadani Mehdi
- Hamid Omid
- Hamieh Mohamad
- Hamilton Garth
- Hammill Joanne
- Hamzaoui Kamel
- Handy John
- Hank Jacquelyn A.
- Hanks Brent
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- Hanson Jodi
- Harada Yui
- Harder Nathalie
- Hare Thomas W.
- Harrington Kevin
- Hartig Greg
- Hartmann Arndt
- Hartnett Jim
- Harvey Christopher
- Hastings William D.
- Hata Chelsie Y.
- Hatz Rudolf
- Haussler David
- Havel Jonathan
- Havunen Riikka
- Haydu Lauren E.
- Haymaker Cara
- He Li-Zhen
- He Ming-Xiao
- Heath Elisabeth
- Hedvat Michael
- Heery Christopher
- Heery Christopher R.
- Hegde Meenakshi
- Helman Sarah R.
- Helsen Christopher
- Helwig Christoph
- Hembrough Todd
- Hemminki Akseli
- Hendricks Kyle
- Henningsohn Lars
- Henry MaryBeth
- Hermitte Fabienne
- Herzog Thomas
- Hessel Harald
- Hinner Marlon J.
- Hinrichs Christian S.
- Hirsch Brooke
- Hirsch Heather A.
- Hirshfield Kim M.
- Hodge James W.
- Hodgson Darren R.
- Hodkinson Brendan P.
- Hoerr Ingmar
- Holdich Tom
- Holtzhausen Alisha
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- Hong Henoch S.
- Hong Ruey-Long
- Horne William
- Horton Brendan
- Houot Roch
- Hovgaard Dorrit
- Howe Karen
- Howells-Ferreira Ana
- Hoyt Clifford
- Hsiao Chin-Fu
- Hsu Jennifer
- Hu Xintao
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- Huber Rudolf M.
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- Hulett Tyler
- Huss Ralf
- Hutnick Natalie A.
- Hutson Thomas
- Hwang Jimmy
- Hwu Patrick
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- Hyland Fiona
- Hylander Bonnie
- Höglund Martin
- Ignacio Eduardo
- Iida Shinsuke
- Jagannath Sundar
- Jaiswal Ashvin
- Jakobsen Bent
- Jallas Anne-Catherine
- James Marihella
- Jandus Camilla
- Jaquin Thomas
- Jayant Kumar
- Jennewein Lukas
- Jenq Robert
- Jensen Shawn
- Jeyakumar Ghayathri
- Ji He
- Jiang Aimin
- Jin Benjamin
- Jing Junping
- Jing Weiqing
- Jochems Caroline
- Joe Andrew
- Johnson Bryon D.
- Johnson Donald
- Johnson Lisa
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- Joseph Sujith
- Joshi Bharat H.
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- Joy Mary
- Juhler-Nøttrup Trine
- June Carl H.
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- Jurisica Igor
- Jäger Dirk
- Kaiser Andrew
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- Kallergi G.
- Kalra Mamta
- Kamat Ashish
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- Kamenyeva Olena
- Kammula Udai
- Kane Michael
- Kang S Peter
- Kang S. Peter
- Kangas Takashi O.
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- Karlsson Hannah
- Karp Judith E.
- Karpathy Roberta
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- Kim Dae Won
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- Kim Joseph W.
- Kim Kyoung-Mee
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- Kjeldsen Julie Westerlin
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- Kolrep Ulrike
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- Krarup-Hansen Anders
- Krenciute Giedre
- Kriley Isaac
- Krishnan Suba
- Krogsgaard Michelle
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- Ku Yuan-Chieh
- Kudchadkar Ragini
- Kulesz-Martin Molly F.
- Kulkarni Anupriya
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- Kuruvilla John
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- Levitsky Victor
- Levy Ronald
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- Nguyen Khue
- Nguyen Phuong
- Nguyen Sang
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- Nishimura Michael
- Noffsinger Lori
- Norris Christie
- Nosrati Adi
- Nunez-Cruz Selene
- Oaknin Ana
- Obeid Joseph M.
- Ocio Enrique
- Odunsi Kunle
- Ogden Julia
- Oh William
- Ohanian Arpy
- Olencki Thomas
- Omilian Angela R.
- Opat Stephen
- Orford Keith W.
- Osman Iman
- Ott Patrick A.
- Ott Sascha
- Ottoson Nadine
- Overacre Abigail
- Overwijk Willem W.
- O’Connor Alison
- O’Neil Bert
- O’Neill Thomas
- Padda Sukhmani K.
- Page David
- Pagès Franck
- Pal Sumanta
- Pamer Eric
- Pan Fan
- Panda Anshuman
- Pandha Hardev
- Pandite Lini
- Pankov Alex
- Papadopoulos Kyriakos P.
- Pardoll Drew
- Paria Biman
- Parihar Robin
- Park Emily
- Park Jiwon
- Park Johanna
- Parney Ian F.
- Parviainen Suvi
- Pasetto Anna
- Patel Sapna P.
- Patnaik Amita
- Patsoukis Nikolaos
- Patterson James W.
- Paulos Chrystal
- Pavlakis George
- Pavlick Anna C.
- Payabyab Eden
- Pedersen Magnus
- Pegram Mark D.
- Peled Jonathan
- Pelletier Sandy
- Perales Miguel
- Perez-Garcia Arianne
- Perini Rodolfo
- Periyasamy Sankar
- Perlewitz Kelly
- Pestic-Dragovich Lidija
- Petersen Christopher
- Petersen Michael Mørk
- Peterson Tim
- Petroni Gina
- Petruzelka Lubos
- Pfeil Jacob
- Pham Hung
- Piha-Paul Sarina A.
- Pilon-Thomas Shari
- Pinzon-Ortiz Maria
- Piperdi Bilal
- Plimack Elizabeth
- Poehlein Christian
- Poggionovo Cécile
- Polaske Nathan
- Polesso Fanny
- Poplin Elizabeth
- Poplonski Tomasz
- Postow Michael
- Powderly John
- Powell Daniel J.
- Powles Thomas
- Pratte Luke
- Prickett Todd D.
- Pritchard Theresa
- Puhlmann Markus
- Puri Raj K.
- Qi Jingjing
- Qiao Guanxi
- Qin Haiying
- Qin Yong
- Qin Zhen
- Quattrini Adriano
- Quinn David
- Rabinovich Brian
- Racolta Adriana
- Rafelson William
- Rahma Osama E.
- Raje Noopur
- Rajurkar Mihir
- Ramachandra Murali
- Ramachandra Raghuveer
- Ramachandran Indu
- Ramakrishna Venky
- Ramakrishnan Rupal
- Ranheim Erik A.
- Rao Arjun A.
- Rashid Rumana
- Rattray Rogan
- Ravindranathan Sruthi
- Razai Amir S.
- Reagan John L.
- Reckamp Karen
- Reddy Ashok
- Reddy Praveen
- Reeves Jason
- Repasky Elizabeth
- Restifo Nicholas P.
- Reu Simone
- Reuben Alex
- Ribas Antoni
- Ribrag Vincent
- Ricca Jacob
- Richards Allison
- Richards Jon
- Richman Sarah A.
- Rickel Erika
- Riddell Stanley
- Riedlinger Greg
- Riemer Joanne
- Rifkin Robert
- Rimm David
- Rina Hui
- Rini Brian I.
- Rittase William
- Rivas Charlotte
- Rivera Miguel
- Robbins Paul F.
- Robida Mark
- Robinson Matthew K.
- Rocafiguera Albert Oriol
- Roder Heinrich
- Roder Joanna
- Rodriguez Kori Porosnicu
- Rodriguez Luis Paz-Ares
- Rodriguez-Garcia Alba
- Rodriguez-Rodriguez Lorna
- Rodríguez-Otero Paula
- Roen Diana
- Roman Kristin
- Romero Pedro
- Rong Xianhui
- Rooney Cliona M.
- Rosen Frances
- Rosenberg Steven
- Rosenberg Steven A.
- Rosenblum Michael
- Rosner Gary
- Ross Ashley
- Ross Jeffrey
- Rossi John M.
- Rothe Christine
- Royster Erica
- Rubinstein Mark
- Ruella Marco
- Rufer Nathalie
- Rush Elizabeth
- Ruzich Janet
- Rådestad Emelie
- Sabado Rachel
- Sabesan Arvind
- Sachsenmeier Eliot
- Sacris Erlinda
- Sadelain Michel
- Saenger Yvonne
- Saini Manoj
- Salama Sofie
- Salazar Andres M.
- Salazar Rachel
- Salles Gilles
- Samiulla Dodheri
- San-Miguel Jesus
- Sanborn Rachel E.
- Sanchez Katherine
- Sander Cindy
- Sanderson Joseph P.
- Sandhu Shahneen
- Sandoval Juan
- Sankin Alexander
- Santiago Laurelis
- Santos João
- Sanz Laia Masvidal
- Saraf Sanatan
- Sarnaik Amod
- Sasikumar Pottayil
- Sathyanaryanan Sriram
- Saunders Tracie
- Savoldo Barbara
- Schadendorf Dirk
- Schaffer Michael E.
- Schalper Kurt
- Scharping Nicole
- Schauder David
- Schaue Dorthe
- Scheel Birgit
- Schiller Annemarie
- Schjesvold Fredrik
- Schlom Jeffrey
- Schloss Charles
- Schlosser Corinna
- Schmidinger Manuela
- Schmidt Guenter
- Schneck Jonathan
- Schoenberg Mark
- Schoenmeyer Ralf
- Scholler John
- Schreiber Taylor H.
- Schult Silke
- Schvartsman Gustavo
- Schwartz Sarit
- Schüler Julia
- Segal Neil H.
- Seiwert Tanguy
- Sellappan Shankar
- Sethuraman Jyothi
- Sewell Andrew Kelvin
- Sgourakis Nikolaos
- Sha Huizi
- Shafren Darren
- Shah Jatin
- Shah Sumit A.
- Shamsili Setareh
- Shane Olwill A.
- Shankaran Veena
- Sharfman William
- Sharma Prannda
- Sharma Sherven
- Sharon Elad
- Sharpe Alan D.
- Shaw Pamela
- Shayan Gulidanna
- Shekarian Tala
- Shen Yueh-wei
- Sher Xinwei
- Sherman Marika
- Sherry Richard
- Shestova Olga
- Shields Anthony
- Shinners Nicholas
- Shinwari Nabeegha
- Shipp Margaret
- Shortt Jake
- Shree Ankita
- Shu Jenny
- Shukla Sachet A.
- Sidhom John-William
- Siefker-Radtke Arlene
- Sievers Eric
- Signoretti Sabina
- Sikic Branimir I.
- Silk Ann
- Silk Jonathan D.
- Silski Cynthia
- Simard François
- Simpson Guy
- Sirard Cynthia
- Siurala Mikko
- Skalova Helena
- Slawin Kevin
- Slingluff Craig L.
- Small William
- Smith David C.
- Smith Sean G.
- Smolkin Mark E.
- Snzol Mario
- Sodre Andressa
- Sokol Levi
- Somerville Robert
- Sondel Paul M.
- Song James
- Song Yang
- Sonpavde Guru
- Soon-Shiong Patrick
- Sosman Jeffrey
- Spacek Jan
- Speiser Daniel E.
- Spencer Christine
- Spencer David M.
- Spires Vanessa M.
- Sprague Isaac
- Spranger Stefani
- Spreafico Anna
- Srinivasa Sreesha P.
- Srivastava Abhishek
- Staffas Anna
- Stagg John
- Stecha Pete
- Stein Mark
- Steinbach Joachim P.
- Steingrimsson Arni
- Steinmetz Sue
- Stern Joshua
- Stevanovic Sanja
- Stewart John
- Stief Christian
- Storey James
- Stramer Amanda
- Stump Julia
- Sturgill Ian
- Su Nan
- Su Paul
- Su Shu
- Subbiah Vivek
- Sudarshan Naremaddepalli
- Suh Robert
- Suisham Stacey
- Sullivan Ryan J.
- Sun Cheng
- Sun Yongming
- Sundarapandiyan Karuna
- Sundararaman Srividya
- Sundberg Berit
- Supan Dana
- Suryawanshi Satyendra
- Suzuki Akiko
- Svane Inge Marie
- Swaby Ramona F.
- Swann Suzanne
- Swanson Ryan
- Swiderski Piotr
- Szomolay Barbara
- Takimoto Chris H.
- Tan Xuemei
- Tang Lei
- Tang Shande
- Tannir Nizar M.
- Tarhini Ahmad A.
- Taur Ying
- Tawbi Hussein
- Taylor Katrina A.
- Tewari Krishnansu S.
- Teyssier Noam
- Thakur Archana
- Theiss Noah
- Thibault Guillaume
- Thomas Lawrence J.
- Thompson John
- Thompson Lucas
- Thompson Seth
- Throsby Mark
- Thyparambil Sheeno
- Tian Zhigang
- Tilman Rau T.
- Timmer John C.
- Ting David
- To Ka Fai
- Tom Warren
- Tonn Torsten
- Topalian Suzanne
- Toth Kyle
- Tran Ben
- Trebska-McGowan Kasia
- Trehu Elizabeth
- Tribble Nicholas
- Trimble Cornelia L.
- Tsai Katy
- Tsang Kwong
- Tsao Tsu-Shuen
- Tsourkas Andrew
- Tsujikawa Takahiro
- Tufman Amanda
- Tumeh Paul
- Tumeh Paul C.
- Turcotte Simon
- Tykodi Scott
- Uemura Marc
- Uger Robert
- Uhlik Mark
- Uhlin Michael
- Urba Walter
- Uribe Diana
- Vaishampayan Ulka
- Valsesia-Wittmann Sandrine
- van den Brink Marcel R. M.
- Van den Eynde Marc
- van Hoef Vincent
- van Loo Pieter Fokko
- Vandeven Natalie
- Varadarajan Navin
- Varadhachary Gauri R.
- Vasaturo Angela
- Vaske Charles
- Vasselli James
- Veerapathran Anandaraman
- Velcheti Vamsidhar
- Veninga Henrike
- Vetsika E-K
- Vignali Dario
- Villabona Lisa
- Villalobos Victor M.
- Villarroel Patricio Pérez
- Viller Natasja Nielsen
- Vitale Laura A.
- Vocka Michal
- Volkmer Jens-Peter
- Voss Martin
- Vuyyuru Raja
- Wagner Joel P.
- Wakefield Jessica
- Wakelee Heather A.
- Waldmann Anja
- Waldmann Thomas
- Wallace William D.
- Waller Edmund K.
- Walser Tonya C.
- Walsh William
- Wan Ee
- Wang Chichung
- Wang Chun-Wei
- Wang Daqing
- Wang Gerald
- Wang Hao
- Wang Judy S.
- Wang Lai
- Wang Ziming
- Wardell Seth
- Wargo Jennifer
- Warren Sarah
- Wassman Karl
- Watkins Simon
- Webb Tonya J.
- Weber James
- Weber Jeffrey
- Weber Sharon
- Webster Philippa
- Wei Ziewn
- Weidlick Jeffrey
- Weigel Tracey
- Weinberg Andrew
- Weissbrich Bianca
- Weissman Irving L.
- Wels Winfried S.
- Wennerberg Erik
- Wenthe Jessica
- Westergaard Marie Christine Wulff
- Whetstone Ryan
- White Andrew M.
- White Eileen
- Whiting Sam
- Widger Jenifer
- Wiedenmann Alexander
- Wiedermann Guy
- Wiegand Volker
- Wiener Doris
- Wigginton Jon
- William Loging
- Williams Jason B.
- Williams LaTerrica C.
- Winter Hauke
- Withers Sita
- Witjes J. Alfred
- Witt Kristina
- Wolchok Jedd D.
- Wolfson Martin
- Wondyfraw Nebiyu
- Wong Philip
- Wong Ryan
- Woodman Scott
- Woods David
- Workman Creg
- Wu Catherine J.
- Wu Haiyan
- Wu Jennifer
- Wunderlich John
- Wydro Mateusz
- Xiao Christine
- Xiao Weihua
- Xin Gang
- Xu Hui
- Xue Allen
- Yamamoto Tori
- Yanagawa Jane
- Yang James
- Yang Jason
- Yang Richard
- Yearley Jennifer
- Yee Andrew J.
- Yee Cassian
- Yehuda Dina Ben
- Yigitsoy Mehmet
- Yimer Habte
- Yonemitsu Yoshikazu
- Yoshino Takayuki
- Yu Evan Y.
- Yu Wendy
- Yu Xuezhong
- Yu Zhiya
- Yusko Erik
- Zacharakis Nikolaos
- Zaharoff David
- Zamarin Dmitriy
- Zang Xingxing
- Zanhow Cynthia
- Zappasodi Roberta
- Zarour Hassane
- Zavadova Eva
- Zehn Dietmar
- Zeng Gang
- Zeng Xue
- Zha Yuanyuan
- Zhang Bingqing
- Zhang Congcong
- Zhang Hongjun
- Zhang Hua
- Zhang Hui
- Zhang Jian
- Zhang Jinyu
- Zhang Liping
- Zhang Maggie
- Zhang Wenjun
- Zhang Xiaonan
- Zhang Yayan
- Zhao Fei
- Zhao Xingli
- Zhao Zeguo
- Zhong Shi
- Zhu Baogong
- Zhu Cheng
- Zhu Yifei
- Zi Tong
- Zimarino Carlo
- Zinzani Pier Luigi
- Zoon Kathryn C.
- Zuleger Cindy
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 03/01/2017
- Field of study
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one
- Author
- Aarts Craig
- Abdallah Rehab
- Abdul-Alim Siddiq
- Abolhalaj Milad
- Abtin Fereidoun
- Acheson Anupama
- Acquavella Nicolas
- Adams Gregory P
- Adams Katherine
- Adams Sharon
- Adamus Tomasz
- Adekandi Madhukara
- Adurthi Sreenivas
- Adusumilli Prasad S
- Aeffner Famke
- Afentoulis Michael
- Ager Casey
- Aggouraki Despoina
- Agrawal Rajendra
- Agrawal Sudhir
- Agrawal Swati
- Ahlers Christoph M
- Ahmed Nabil
- Ahn Myung J
- Ahr Katya
- Ai Midan
- Aiba Rachida-Siham B
- Aisner Joseph
- Albertini Mark R
- Albertini Mark R
- Albiges Laurence
- Albright Andrew
- Albright Andrew
- Algazi Alain
- Ali Siraj
- Alicea Candido
- Allen Natalie
- Allersdorfer Andrea
- Alva Ajjai
- Amado Rafael
- Amaria Rodabe
- Ameratunga Malaka
- Amin Asim
- Amor Amira B
- Amrhein John
- Anagnostou Valsamo
- Andersen Rikke
- Andersen Rikke
- André Thierry
- Andtbacka Robert H I
- Angela Omilian
- Angell Helen K
- Annels Nicola
- Annunziata Christina M
- Ansa-Addo Ephraim A
- Ansari Tameem
- Antilla Marjukka
- Antonarakis Emmanuel S
- Antonarakis Emmanuel S
- Aoki Rhonda
- Armand Philippe
- Armand Philippe
- Armstrong Adam
- Arora Kshitij
- Arreaza Gladys
- Ascierto Paolo A
- Ashworth-Sharpe Julia
- Askmyr David
- Asmellash Senait
- Assadipour Yasmine
- Assenmacher Mario
- Athelogou Maria
- Atkins Michael B
- Atkins Michael B
- Atkins Michael B
- Attaf Meriem
- Au Gough
- Au-Young Janice
- Avery Kendra N
- Avery Kendra N
- Ayers Mark
- Ayers Mark
- Ayers Mark
- Azimi Vahid
- Aznar M. A
- Backert Linus
- Backes Floor J
- Bagg Eleanor A L
- Bahjat Keith
- Bajorin Dean
- Bakker Lex
- Balakumaran Arun
- Balakumaran Arun
- Balakumaran Arun
- Ballesteros-Merino Carmen
- Ballesteros-Merino Carmen
- Ballesteros-Merino Carmen
- Bander Neil
- Bang Yung-Jue
- Bannerji Rajat
- Baratelli Felicita E
- Barbee Susannah D
- Barlesi Fabrice
- Barrett Carl
- Barrett David
- Barth Carola
- Bartkowiak Todd
- Bartlett Nancy
- Basher Fahmin
- Bassett Roland
- Bassett Roland
- Basu Samik
- Bath Natalie
- Batista Luciana
- Bauer Todd
- Bauer Todd M
- Bauer Todd W
- Baughman Jan E
- Bayle J. H
- Baylin Stephen
- Beechem Joseph
- Beechem Joseph
- Beechem Joseph
- Beeson Craig
- Bellmunt Joaquim
- Bellmunt Joaquim
- Bellovin David I
- Beltran Nancy
- Bendell Johanna
- Bender James
- Bender James
- Bender James
- Bennett Alan D
- Bennett Mark K
- Bergamaschi Cristina
- Berger Frank
- Berger Sven
- Bergeron Derek
- Berglund Anders
- Berglund Sofia
- Bernatchez Chantale
- Bernett Matthew J
- Bernett Matthew J
- Bernstein Donna
- Bessell Catherine A
- Betts Gareth
- Beyer Sophie
- Bhanot Gyan
- Bhardwaj Nina
- Bhardwaj Nina
- Bhardwaj Nina
- Bhardwaj Rukmini
- Bhatia Shailender
- Bhatia Shailender
- Bhaumik Srabani
- Bianchi Valentina
- Bielamowicz Kevin
- Bieniarz Christopher
- Bifulco Carlo
- Bifulco Carlo
- Bifulco Carlo
- Bifulco Carlo
- Billingsley James M
- Binder-Scholl Gwendolyn
- Binder-Scholl Gwendolyn
- Binnig Gerd
- Birditt Brian
- Bivalacqua Trinity J
- Black Joshua C
- Black Joshua C
- Black Mary
- Blacklock Hilary
- Blackmon Shauna
- Blackmon Shauna
- Blaskovich Michelle A
- Blaskovich Michelle A
- Blaskovich Michelle A
- Blazar Bruce R
- Blitzer Grace
- Bonzon Christine
- Bonzon Christine
- Borch Troels H
- Borch Troels H
- Borges Luis
- Borkar Rohan N
- Bornschlegl Svetlana
- Bornschlegl Svetlana
- Bosch Marnix
- Bose Nandita
- Bossen Bolette
- Bot Adrian
- Botti Gerardo
- Boudadi Karim
- Boussiotis Vassiliki A
- Brahmer Julie
- Bramson Jonathan
- Bramson Jonathan
- Brenner Malcolm K
- Brett Sara
- Brevard Julie
- Brewer Joanna
- Brieu Nicolas
- Brisson Ryan
- Brody Joshua
- Brunazzi Erin
- Bruno Tullia C
- Bryant Bonita
- Bshara Wiam
- Bu Xia
- Buchner Alexander
- Bucsek Mark
- Budhani Pratha
- Bullock Timothy N
- Bullock Timothy N
- Burger Michael C
- Burgess Melissa
- Burgher Blake
- Burgher Blake
- Burk Chad
- Butterfield Lisa H
- Byrd David
- Byrd John
- Byrd Tiara
- Callahan Margaret K
- Campbell Mary
- Campbell Tracy
- Canter Robert J
- Canter Robert J
- Cao Alexander
- Carmichael Lakeesha
- Caron Christine
- Carpentier Sabrina
- Carpio Cecilia
- Carretero-Iglesia Laura
- Carvajal-Hausdorf Daniel
- Caspell Richard
- Caux Christophe
- Cecchi Fabiola
- Celis Esteban
- Cerkovnik Logan
- Cervera-Carrascón Víctor
- Chacon Jessica
- Chagin Karen
- Chakraborty Paramita
- Champagne Monique
- Chan Anthony T C
- Chan Nancy
- Chan Timothy A
- Chandran Smita
- Chandrasekhar Talapaneni
- Chang Peter
- Chang Serena
- Chao Mark
- Chatterjee Shilpak
- Chaudhri Apoorvi
- Cheever Martin
- Chen Amanda
- Chen Hui
- Chen Jie Q
- Chen Lawrence
- Chen Lieping
- Chen Mei
- Chen Mingyi
- Chen Shuming
- Chen Xiufen
- Cheng Jonathan
- Cheng Jonathan
- Cheng Zhi-jie J
- Chikina Maria
- Chin Renee
- Chinnasamy Harshini
- Chlosta Sabine
- Chlosta Sabine
- Choi Minsig
- Choueiri Toni K
- Choueiri Toni K
- Christian Beth
- Chu Liz
- Chu Seung
- Chu Seung
- Chunduru Srinivas
- Clark Joseph I
- Clayburgh Daniel R
- Clement Amanda
- Clements Erin
- Cohen Lewis
- Cohen Zvi
- Colevas A D
- Collins Jennifer
- Colyer Duncan
- Cong Mei
- Conlin Alison
- Conlon Kevin
- Conrad Valerie
- Conroy Jeff
- Conroy Jeff
- Copeland Larry
- Copploa Domenico
- Cordes Lisa
- Cornfeld Mark
- Cortina Luis
- Coussens Lisa M
- Couto Joseph
- Coveler Andrew L
- Crabill George
- Cristescu Razvan
- Cristescu Razvan
- Crocker Andrea
- Cui Weiguo
- Culp William
- Cumberbatch Kerwin
- Curran Michael
- Curti Brendan
- Curti Brendan
- Curti Brendan
- Curti Brendan
- Dadey Rebekah
- Daenthanasanmak Anusara
- Dai Zhimin
- Damare Sherri
- Dammassa Ernesta
- Danaher Patrick
- Danaher Patrick
- Danforth David
- Daud Adil
- Davar Diwakar
- Davenport Anna
- David Larry
- Davies Bronwyn
- Davies Michael A
- Davies Michael A
- Davis Tom
- De Bono Johann
- De Macedo Mariana P
- de Oliveira Moacyr R
- De Santis Maria
- de Wit Ronald
- Deacon Donna H
- Deacon Donna H
- Deeds Michael
- Del Pilar Estevez Diz Maria
- Delcommenne Marc
- Delgoffe Greg M
- Delgoffe Greg M
- Delgoffe Greg M
- Delismon Judy
- Denisova Galina
- Dennis Lucas
- Dennis Lucas
- Deol Abhinav
- Derakhshandeh Roshanak
- DeRenzo Christopher
- Desai Jayesh
- Desai Niyati
- Deshpande Amit
- Deshpande Amit
- Deshpande Vikram
- Desjarlais John
- Desjarlais John
- Deveraux Quinn
- DeVito Anna M
- Devlin Sean
- Dey Chaitali
- Dhudashia Amit
- di Pietro Alessandra
- Diab Adi
- Diaz Luis A
- Diaz-Lagares Angel
- Dietz Allan B
- Dietz Allan B
- Ding Naiqing
- Ding Wei
- Disis Mary L
- Dobson Jason R
- Docta Roslin
- Dolstra Harry
- Dolton Garry
- Donda Alena
- Donia Marco
- Donia Marco
- Donia Marco
- Donovan Michael J
- doo Chang Young
- Doody Jacqueline
- Dotti Gianpietro
- Dougherty Janna
- Downing Sean
- Dragnev Konstanin
- Drake Charles G
- Drake Charles G
- Dranoff Glenn
- Draper Lindsey M
- Drechsel Katharina
- Dreicer Robert
- Dubay Christopher
- Dubay Christopher
- Dubey Aparajita
- Dubinett Steven M
- Dubois Sigrid
- Duhen Rebekka
- Duhen Thomas
- Dummer Reinhard
- Dunaway Dwayne
- Dunaway Dwayne
- Duncan Brynn
- Dundr Pavel
- Duong MyLinh
- Dutour Aurélie
- Dyson Gregory
- D’Amico Leonard
- Eagan Maribeth A
- Early Brandon
- Eckelman Brendan P
- Egevad Lars
- Ehrmann Jon M
- El Rassi Edward
- Elashoff David A
- Elliott Nathan
- Emens Leisha
- Enblad Gunilla
- Erdag Gulsun
- Erdag Gulsun
- Ernstoff Marc S
- Ernstoff Marc S
- Essand Magnus
- Esteller Manel
- Evans Kathy
- Evans Lawrence
- Eyquem Justin
- Fakhrejahani Farhad
- Falchook Gerald
- Fan Aaron
- Fan Frank
- Fang Victoria
- Fantini Massimo
- Fardis Maria
- Fardis Maria
- Faries Mark
- Faroudi Mustapha
- Farrell Michael
- Fast Loren
- Felber Barbara
- Feldman Steven A
- Feng Dai
- Fernando Ingrid
- Ferris Robert
- Ferris Robert L
- Ferris Robert L
- Fieschi Jacques
- Fisher George A
- Fling Steven
- Fling Steven
- Flint Paul W
- Forrest-Hay Alex
- Fosco Dominick
- Foster Aaron E
- Fotin-Mleczek Mariola
- Fousek Kristen
- Fox Bernard
- Fox Bernard
- Fox Bernard
- Fox Bernard
- Fox Bernard
- Fox Maxine
- Francis Nicole
- Frank Ian
- Frank Ian
- Frankel Melissa
- Fraser Kathryn
- Frayssinet Véronique
- Freeman Gordon J
- Freese Katharina
- Frey Alan
- Friedlander Michael L
- Friedlander Philip
- Friedlander Philip
- Friedlander Philip
- Fritsch Edward
- Fry Terry
- Fu Siqing
- Fujii Rika
- Fulton Ross B
- Gajewski Thomas F
- Gajewski Thomas F
- Gajewski Thomas F
- Galon Jérôme
- Gan Hui
- Gan Jacek
- Ganesan Shridar
- Gangadhar Tara C
- Gangxiong Huang
- Gao Qian
- Gardai Shyra J
- Gardner Mark
- Garon Edward B
- Garon Edward B
- Garrabrant Thomas
- Garrett-Mayer Elizabeth
- Gartner Jared J
- Gartner Jared J
- Gartrell Benjamin
- Garvin Denise
- Gastineau Dennis A
- Gastineau Dennis A
- Gastman Brian
- Gause Christine
- Geib James
- Geiss Gary
- Geller Melissa
- Georgoulias V.
- Gerken Claudia
- Gerry Andrew
- Gerry Andrew
- Gershan Jill
- Gershenson Zack
- Ghaffari Mahsa
- Ghori Razi
- Gianani Roberto
- Gianani Roberto
- Gilden Julia
- Gill Saar
- Gillies Stephen D
- Giralt Sergio
- Giri Rajanish
- Gitlitz Barbara
- Giver Cynthia R
- Glenn Sean
- Glenn Sean
- Glitza Isabella
- Glitza Isabella
- Glod John
- Gnad-Vogt Ulrike
- Goel Sanjay
- Goff Stephanie
- Goff Stephanie L
- Goff Stephanie L
- Gojo Ivana
- Gokuldass Aishwarya
- Gokuldass Aishwarya
- Goldinger Simone
- Goldman Jonathan W
- Goldschmidt Hartmut
- Goldstein Joel
- Gonzalez Denise
- Gonzalez Iliana
- Gonzalez Ricardo
- Gorden Keith
- Gormley Michael
- Gottschalk Stephen
- Gottschalk Stephen
- Gottschalk Stephen
- Govindappa Nagaraja
- Gowda Nagaraj
- Gowda Nagesh
- Graff Jeremy
- Grailer Jamison
- Graziano Robert F
- Green Daniel S
- Gregory Gareth
- Greiff Lennart
- Grilley-Olson Juneko E
- Grimaldi Antonio
- Grose Mark
- Grose Mark
- Gross Matt
- Grossenbacher Steven
- Grossenbacher Steven K
- Grupp Stephan
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- Wydro Mateusz
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- Publication venue
- Publication date
- 27/03/2018
- Field of study
Recommended from our members
Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial
- Author
- Aagaard Bitten
- Accardi Evan
- ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group
- Adam Stacey J
- Adams Amy
- Agarwal Trisha
- Aggarwal Neil R
- Akbari Freshta
- Albert Sara
- Alexander Elizabeth
- Almasri Eyad
- Alvarez Michael S
- Ames DeAnna
- Amos Laura
- Amosu Omowunmi
- Andreassen Helle Frost
- Applegate Darrin
- Armbruster Brent P
- Arribas Jose R
- Ashktorab Kimia
- Ashok Kiran
- Aston Valerie T
- Audette Matthew
- Babiker Abdel G
- Badhwar Vinay
- Badrock Jonathan
- Baduashvili Amiran
- Bagiella Emilia
- Baio Kim T
- Baker Jason V
- Baker Rebecca
- Bakowska Elizieta
- Balde Abby
- Banner-Goodspeed Valerie
- Bansal Aditya
- Baracco Gio
- Baracz Michelle
- Barkauskas Christina E
- Barrett Kevin
- Barros Andrew
- Bartolo Elizabeth Berry
- Baseler Beth
- Baumgarten Katherine
- Bayoumi Emad
- Beakes Caroline
- Becker Nancy
- Bednarska Agnieszka
- Bedoya Gabriela
- Bender William
- Bergsøe Christina Marisa
- Berhe Mezgebe
- Bettacchi Christopher
- Beutler Rebecca
- Bielica Mona
- Bienstock Karen
- Billouin-Frazier Shere
- Bissel Brittany
- Biswas Kousick
- Bjork Lauren
- Bledsoe Joseph
- Bojesen Ane
- Bokhart Gordon
- Bouffler Andrew
- Bowdish Michael E
- Boyle Katherine L
- Brait Kelsey
- Brar Indira
- Braun Dominique L
- Broussard Shane
- Brower Roy G
- Brown Craig
- Brown Samuel
- Brown Samuel M
- Bruun Tina
- Buck Theresa
- Bunner Robin
- Burgos Joaquin
- Burris Sarah
- Buterbaugh Sabrina
- Cabrera Gesalit
- Caccia Taylor
- Cahill Kelly
- Cao Huyen
- Carey Catherine
- Carlsen Amy
- Carter Anita
- Casey Jonathan D
- Cash Jennifer
- Cassity Evan P
- Caudill Antonina
- Chang Christina C
- Chang Steven Y
- Chauhan Lakshmi
- Chen Peter
- Chi Andrew
- Chia Po Ying
- Chiu Charlene
- Chiu Joseph
- Choe June
- Choudhary Jay
- Clapham Gregg J
- Clariday Laura
- Clausen Clara Lundetoft
- Co Ivan N
- Coleman Tanquinisha
- Cook Sharri
- Cothran Elizabeth
- Crew Page
- Crovetto Nicolle
- Currier Judy
- Davey Victoria J
- Davis Allyson
- Davis Bionca
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- Denning Eileen
- Der Tatyana
- Deshmukh Rupali
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- Dhar Sanjay
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- Ding Xiao
- Dinh Huan
- Diong Shiau Hui
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- Dixon Mary
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- Douglas Ivor
- Douin David J
- Dreyer Grace R
- DuChateau Nadine
- DuChene Alain
- Duggal Abhijit
- Duhaime Erin
- Duque Krizia
- Eichinger Mareile L
- Eichman Sharon M
- Enfield Kyle B
- Engen Nicole
- Escobar Jose
- Esmann Frederik V.L
- Estrada Vicente
- Evans Raquel
- Exposito Maria
- Eyler Carolyn
- Fabricius Thilde
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- Fernández-Cruz Eduardo
- Fielding Michele
- Filbin Michael R
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- Gardner Edward M
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- Gelijns Annetine C
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- Gerstoft Jan
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- Gibbs Keven W
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- Gillinov Marc A
- Ginde Adit A
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- More Harshada
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- Wiese Lothar
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- Woldbye Frederik
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- Yan Li
- Yee Kimberly J
- Yeo Tsin Wen
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- Zheng Yiling
- Zhong Amy
- Zhu Qing
- Zhuo Hanjing
- Zink Veronika
- Zuckerman Judith
- Zuckerman Richard A
- Østergaard Lars
- Publication venue
- Elsevier Ltd
- Publication date
- 01/05/2022
- Field of study
We aimed to assess the efficacy and safety of two neutralising monoclonal antibody therapies (sotrovimab [Vir Biotechnology and GlaxoSmithKline] and BRII-196 plus BRII-198 [Brii Biosciences]) for adults admitted to hospital for COVID-19 (hereafter referred to as hospitalised) with COVID-19.
In this multinational, double-blind, randomised, placebo-controlled, clinical trial (Therapeutics for Inpatients with COVID-19 [TICO]), adults (aged ≥18 years) hospitalised with COVID-19 at 43 hospitals in the USA, Denmark, Switzerland, and Poland were recruited. Patients were eligible if they had laboratory-confirmed SARS-CoV-2 infection and COVID-19 symptoms for up to 12 days. Using a web-based application, participants were randomly assigned (2:1:2:1), stratified by trial site pharmacy, to sotrovimab 500 mg, matching placebo for sotrovimab, BRII-196 1000 mg plus BRII-198 1000 mg, or matching placebo for BRII-196 plus BRII-198, in addition to standard of care. Each study product was administered as a single dose given intravenously over 60 min. The concurrent placebo groups were pooled for analyses. The primary outcome was time to sustained clinical recovery, defined as discharge from the hospital to home and remaining at home for 14 consecutive days, up to day 90 after randomisation. Interim futility analyses were based on two seven-category ordinal outcome scales on day 5 that measured pulmonary status and extrapulmonary complications of COVID-19. The safety outcome was a composite of death, serious adverse events, incident organ failure, and serious coinfection up to day 90 after randomisation. Efficacy and safety outcomes were assessed in the modified intention-to-treat population, defined as all patients randomly assigned to treatment who started the study infusion. This study is registered with ClinicalTrials.gov, NCT04501978.
Between Dec 16, 2020, and March 1, 2021, 546 patients were enrolled and randomly assigned to sotrovimab (n=184), BRII-196 plus BRII-198 (n=183), or placebo (n=179), of whom 536 received part or all of their assigned study drug (sotrovimab n=182, BRII-196 plus BRII-198 n=176, or placebo n=178; median age of 60 years [IQR 50–72], 228 [43%] patients were female and 308 [57%] were male). At this point, enrolment was halted on the basis of the interim futility analysis. At day 5, neither the sotrovimab group nor the BRII-196 plus BRII-198 group had significantly higher odds of more favourable outcomes than the placebo group on either the pulmonary scale (adjusted odds ratio sotrovimab 1·07 [95% CI 0·74–1·56]; BRII-196 plus BRII-198 0·98 [95% CI 0·67–1·43]) or the pulmonary-plus complications scale (sotrovimab 1·08 [0·74–1·58]; BRII-196 plus BRII-198 1·00 [0·68–1·46]). By day 90, sustained clinical recovery was seen in 151 (85%) patients in the placebo group compared with 160 (88%) in the sotrovimab group (adjusted rate ratio 1·12 [95% CI 0·91–1·37]) and 155 (88%) in the BRII-196 plus BRII-198 group (1·08 [0·88–1·32]). The composite safety outcome up to day 90 was met by 48 (27%) patients in the placebo group, 42 (23%) in the sotrovimab group, and 45 (26%) in the BRII-196 plus BRII-198 group. 13 (7%) patients in the placebo group, 14 (8%) in the sotrovimab group, and 15 (9%) in the BRII-196 plus BRII-198 group died up to day 90.
Neither sotrovimab nor BRII-196 plus BRII-198 showed efficacy for improving clinical outcomes among adults hospitalised with COVID-19.
US National Institutes of Health and Operation Warp Spee