Chiral Scrambling and Independent Crystallization of D_4, L_4, and D_2L_2 Isomers of an Au^I_4Co^III_2 Hexanuclear Complex with Mixed Penicillaminate and Bis(diphenylphosphino)ethane

This document is the Accepted Manuscript version of a Published Work that appeared in final form in Inorganic Chemistry, © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acs.inorgchem.5b0154

Improvement of Badminton-Player Tracking Applying Image Pixel Compensation

Motion analysis of athletes often provides important information to improve training and strategy meetings. Visual player-tracking techniques are being developed that do not need devices. In this paper, we focus on racket sports, since they suffer from technical issues for visual tracking such as small observation size (low resolution) and large variation of player appearances. Moreover, racket sports video is usually captured by a monocular camera at a set position so that each player is observed at a top and a bottom region of the video across a net on the court. As a result, tracking accuracy is damaged by the net that often occludes players on the far side. As a solution, this paper proposes a method to improve the player-tracking accuracy in badminton video by applying an image pixel compensation technique, such as Image Inpainting. We confirm the effectiveness of our method using videos of badminton singles games

Low-Dose Intravenous Alteplase in Wake-Up Stroke

Background and Purpose—We assessed whether lower-dose alteplase at 0.6 mg/kg is efficacious and safe for acute fluid-attenuated inversion recovery-negative stroke with unknown time of onset. Methods—This was an investigator-initiated, multicenter, randomized, open-label, blinded-end point trial. Patients met the standard indication criteria for intravenous thrombolysis other than a time last-known-well >4.5 hours (eg, wake-up stroke). Patients were randomly assigned (1:1) to receive alteplase at 0.6 mg/kg or standard medical treatment if magnetic resonance imaging showed acute ischemic lesion on diffusion-weighted imaging and no marked corresponding hyperintensity on fluid-attenuated inversion recovery. The primary outcome was a favorable outcome (90-day modified Rankin Scale score of 0–1). Results—Following the early stop and positive results of the WAKE-UP trial (Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke), this trial was prematurely terminated with 131 of the anticipated 300 patients (55 women; mean age, 74.4±12.2 years). Favorable outcome was comparable between the alteplase group (32/68, 47.1%) and the control group (28/58, 48.3%; relative risk [RR], 0.97 [95% CI, 0.68–1.41]; P=0.892). Symptomatic intracranial hemorrhage within 22 to 36 hours occurred in 1/71 and 0/60 (RR, infinity [95% CI, 0.06 to infinity]; P>0.999), respectively. Death at 90 days occurred in 2/71 and 2/60 (RR, 0.85 [95% CI, 0.06–12.58]; P>0.999), respectively. Conclusions—No difference in favorable outcome was seen between alteplase and control groups among patients with ischemic stroke with unknown time of onset. The safety of alteplase at 0.6 mg/kg was comparable to that of standard treatment. Early study termination precludes any definitive conclusions

Chiral Scrambling and Independent Crystallization of d₄, l₄, and d₂l₂ Isomers of an Au^I₄Co^III₂ Hexanuclear Complex with Mixed Penicillaminate and Bis(diphenylphosphino)ethane

The 1:1 mixing of a pair of enantiomers of a cyclic Au^I₄Co^III₂ hexanuclear complex having penicillaminate (pen) and 1,2-bis­(diphenylphosphino)­ethane (dppe), [Au₄Co₂(dppe)₂(d-pen)₄]²⁺ (d₄-[<b>1</b>]²⁺) and [Au₄Co₂(dppe)₂(l-pen)₄]²⁺ (l₄-[<b>1</b>]²⁺), in solution produced an additional stereoisomer, [Au₄Co₂(dppe)₂(d-pen)₂(l-pen)₂]²⁺ (d₂l₂-[<b>1</b>]²⁺), because of the scrambling of [Co­(d-pen)₂]⁻ and [Co­(l-pen)₂]⁻ units between d₄-[<b>1</b>]²⁺ and l₄-[<b>1</b>]²⁺. Upon crystallization with NO₃^–, the three stereoisomers were independently crystallized to form three different kinds of crystals, homochiral crystals of d₄-[<b>1</b>]­(NO₃)₂, homochiral crystals of l₄-[<b>1</b>]­(NO₃)₂, and heterochiral crystals of d₂l₂-[<b>1</b>]­(NO₃)₂, showing a unique example of the self-recognition and organization of three stereoisomers upon crystallization