111 research outputs found

    Scenario analysis in the measurement of operational risk capital: A change of measure approach

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    Abstract At large financial institutions, operational risk is gaining the same importance as market and credit risk in the capital calculation. Although scenario analysis is an important tool for financial risk measurement, its use in the measurement of operational risk capital has been arbitrary and often inaccurate. We propose a method that combines scenario analysis with historical loss data. Using the Change of Measure approach, we evaluate the impact of each scenario on the total estimate of operational risk capital. The method can be used in stress-testing, what-if assessment for scenario analysis, and Loss Given Default estimates used in credit evaluations. Key Words: Scenario Analysis, Operational Risk Capital, Stress Testing, Change of Measure, Loss Data Modeling, Basel Capital Accord. JEL CODES: G10, G20, G21, D81 1 We are grateful to David Hoaglin for painstakingly helping us by editing the paper and making many valuable suggestions for improving the statistical content. We also thank Ravi Reddy for providing several valuable insights and for help with the methodological implementation, Ken Swenson for providing guidance from practical and implementation points of view at an early stage of this work, Karl Chernak for many useful suggestions on an earlier draft, and Dave Schramm for valuable help and support at various stages. We found the suggestions of Paul Embrechts, Marius Hofert, and Ilya Rosenfeld very useful in improving the style, content, and accuracy of the method. We also thank seminar participants at the Fields Institute, University of Toronto, American Bankers Association, Canadian Bankers Association, and anonymous referees for their valuable comments and their corrections of errors in earlier versions of paper. Any remaining errors are ours. Three referees from the Journal of Risk and Insurance provided thoughtful comments that led us to refine and extend our study, and we have incorporated their language into our presentation in several places. The methodology discussed in this paper, particularly in Section 3.1, in several paragraphs of Section 3.2, and in the Appendix, is freely available for use with proper citation. © 2010 by Kabir K. Dutta and David F. Babbel 2 Kabir Dutta is a Senior Consultant to Charles River Associates in Boston. [email protected] 1 Introduction Scenario analysis is an important tool in decision making. It has been used for several decades in various disciplines, including management, engineering, defense, medicine, finance and economics. 1. Evaluation of future possibilities (future states) with respect to a certain characteristic. 2. Present knowledge (current states) of that characteristic for the entity. Scenarios must pertain to a meaningful duration of time, for the passage of time will make the scenarios obsolete. Also, the current state of an entity and the environment in which it operates give rise to various possibilities in the future. In management of market risk, scenarios also play an important role. Many scenarios on the future state of an asset are actively traded in the market, and could be used for risk management. Derivatives such as call (or put) options on asset prices are linked to its possible future price. Suppose, for example, that Cisco (CSCO) is trading today at $23 in the spot (NASDAQ) market. In the option market we find many different prices available as future possibilities. Each of these is a scenario for the future state of CSCO. The price for each option reflects the probability that the market attaches to CSCO attaining more (or less) than a particular price on (or before) a certain date in the future. As the market obtains more information, prices of derivatives change, and our knowledge of the future state expands. In the language of asset pricing, more information on the future state is revealed. At one time, any risk for a financial institution that was not a market or credit risk was considered an operational risk. This definition of operational risk made data collection and measurement of operational risk intractable. To make it useful for measurement and management, Basel banking regulation narrowed the scope and definition of operational risk. Under this definition, operational risk is the risk of loss, whether direct or indirect, to which the Bank is exposed because of inadequate or failed internal processes or systems, human error, or external events. Operational risk includes legal and regulatory risk, business process and change risk, fiduciary or disclosure breaches, technology failure, financial crime, and environmental risk. It exists in some form in every business and function. Operational risk can cause not only financial loss, but also regulatory damage to the business' reputation, assets and shareholder value. One may argue that at the core of most of the financial risk one may be able to observe an operational risk. The Financial Crisis Inquiry Commission Report (2011) identifies many of the risks defined under operational risk as among the reasons for the recent financial meltdown. Therefore, it is an important financial risk to consider along with the market and credit risk. By measuring it properly an institution will be able to manage and mitigate the risk. Financial institutions safeguard against operational risk exposure by holding capital based on the measurement of operational risk. Sometimes a financial institution may not experience operational losses that its peer institutions have experienced. At other times, an institution may have been lucky. In spite of a gap in its risk it didn't experience a loss. In addition, an institution may also be exposed to some inherent operational risks that can result in a significant loss. All such risk exposures can be better measured and managed through a comprehensive scenario analysis. Therefore, scenario analysis should play an important role in the measurement of operational risk. Banking regulatory requirements stress the need to use scenario analysis 2 in the determination of operational risk capital. 4 Early on, many financial institutions subjected to banking regulatory requirements adopted scenario analysis as a prime component of their operational risk capital calculations. They allocated substantial time and resources to that effort. However, they soon encountered many roadblocks. Notable among them was the inability to use scenario data as a direct input in the internal data-driven model for operational risk capital. Expressing scenarios in quantitative form and combining their information with internal loss data poses several challenges. Many attempts in that direction failed miserably, as the combined effect produced unrealistic capital numbers (e.g., 1,000 times the total value of the firm). Such outcomes were typical. As a result, bank regulators relaxed some of the requirements for direct use of scenario data. Instead, they suggested using external loss data to replace scenario data as a direct input to the model. External loss events are historical losses that have occurred in other institutions. Such losses are often very different from the loss experience of the institution. In our opinion, that process reduced the importance of scenarios in measuring operational risk capital. Previously, as well as in current practice, external loss data were and are used in generating scenarios. We believe that the attempts to use scenario data directly in capital models have failed because of incorrect interpretation and implementation of such data. This work attempts to address and resolve such problems. Because scenarios have been used successfully in many other disciplines, we think that scenario data should be as important as any other data that an institution may consider for its risk assessments. Some may question, justifiably, the quality of scenario data and whether such data can be believable. We contend that every discipline faces such challenges. As we will show, the value in scenario data outweighs the inherent weaknesses it may have. Also, through systematic use we will be able to enhance the quality of the data. In this paper we propose a method that combines scenario analysis with historical loss data. Using the Change of Measure approach, we evaluate the impact of each scenario on the total estimate of operational risk capital. Our proposed methodology overcomes the aforementioned obstacles and offers considerable flexibility. The major contribution of this work, in our opinion, is in the meaningful interpretation of scenario data, consistent with the loss experience of an institution, with regard to both the frequency and severity of the loss. Using this interpretation, we show how one can effectively use scenario data, together with historical data, to measure operational risk exposure and, using the Change of Measure concept, evaluate each scenario's effect on operational risk. We believe ours is the first systematic study of the problem of using scenario data in operational risk measurement. In the next section we discuss why some of the earlier attempts at interpreting scenario data did not succeed and the weaknesses of current practices. We then discuss the nature and type of scenario data that we use in our models. Following that, we discuss our method of modeling scenario data and economic evaluation of a set of scenarios in operational risk measurement. We conclude with a discussion of some issues that may arise in implementing the method and of its use in other domains

    Isolation, identification, and antibiogram studies of Salmonella species and Escherichia coli from boiler meat in some selected areas of Bangladesh

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    Background: The present study was carried out for the isolation, identification of Salmonella and Escherichia coli from broiler meat samples (leg muscle, breast muscle and drumstick) which were collected from different upazilla markets of Mymensingh, Gazipur, and Sherpur districts during the period of January 2015 to May 2015.Methods: A total of 60 samples were subjected to bacterial isolation and identification by using cultural, biochemical, and polymerase chain reaction assays.Results: Using standard bacteriological techniques E. coli was isolated from 50 (83.33%) samples and Salmonella spp. from 18 (31.66%) samples. Furthermore, the isolates were subjected to antibiogram studies by disk diffusion method using eight commonly used antibiotics. Antibiogram studies revealed that gentamicin, ciprofloxacin, and norfloxacin were highly sensitive against all the isolated bacteria, whereas most of the isolates were resistant to amoxicillin, erythromycin, and tetracycline. Out of all the isolates, 5 isolates of E. coli and 3 isolates of Salmonella were found multidrug resistant.Conclusions: The study revealed the presence of multidrug resistant Salmonella and E. coli in broiler meat sold in live bird market of different upazilla

    Arsenic Exposure of Mothers and Low Birth Weight

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    Low birth weight (LBW) of the babies was found to be associated with arsenic exposure through consuming arsenic-contaminated water in Bangladesh. But the influences of maternal nutritional status and hemoglobin level remains to be dealt with. This study was conducted to assess the LBW of the babies in reference to arsenic exposure of mothers controlling the influences of the nutritional status (BMI) and hemoglobin level. This was a cross-sectional study carried out amongst the pregnant mothers who came to a district hospital for delivery. The mothers aged ≥18 years and had no complication were included in the study. A total of 101 mothers and their newborn babies were the study sample. Of the total 101 participant mothers, 41.5% were arsenic exposed. Comparatively, on an average, lower birth weight (2492± 477gr) was found among the babies born to arsenic exposed-mother. The exposed mother of LBW babies had significantly a higher urine arsenic concentration (381.38µg/L). The correlation analysis revealed that there was a negative relationship with the urine arsenic concentration (r=-.619; p=.000) and positive relationship with the hemoglobin level (r=.280; p=.092) and BMI (r=.204; p=195) of the exposed mother with the birth weight. After controlling the influence of hemoglobin level and BMI, an almost same association was found between LBW and urine arsenic. Mothers with arsenic exposure were at risk of giving birth to LBW babies, this could increase as evident by higher maternal urine arsenic concentration. And any positive effect of maternal nutritional status and hemoglobin level on birth weight of newborn could be offset by arsenic exposure

    The implementation of decentralised biogas plants in Assam, NE India: the impact and effectiveness of the National Biogas and Manure Management Programme

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    The Indian Government’s National Biogas and Manure Management Programme (NBMMP) aims to deliver renewable energy services to households across the country by incentivising the deployment of family-sized (<6m3) anaerobic (biogas) digesters. We investigated how NBMMP policy is implemented at three levels, from government and state nodal agency, via private contractors to households. We analysed the scheme across two districts in Assam, north-east India, interviewing stakeholders in rural households, state and non-state institutions. We found a top-down, supply-side approach which enables central government to set targets and require individual states to deploy the scheme. Participation in the NBMMP was found to deliver improved energy service outcomes to a majority of households that can afford to participate, although the level of knowledge and understanding of the technology amongst users was limited. Improved training of householders, and particularly women, is needed in relation to the maintenance of digesters, feedstock suitability and the environmental and potential livelihood benefits of digestate. A policy revision which highlights the contextual and demand-side issues around adopting the technology, may deliver monetary benefits from market competition and enable development of community-focused microfinance schemes to improve the affordability of biogas systems

    Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis

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    This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Medicinal Chemistry, Copyright © 2022 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jmedchem.2c00204.The perinucleolar compartment (PNC) is a dynamic subnuclear body found at the periphery of the nucleolus. The PNC is enriched with RNA transcripts and RNA-binding proteins, reflecting different states of genome organization. PNC prevalence positively correlates with cancer progression and metastatic capacity, making it a useful marker for metastatic cancer progression. A high-throughput, high-content assay was developed to identify novel small molecules that selectively reduce PNC prevalence in cancer cells. We identified and further optimized a pyrrolopyrimidine series able to reduce PNC prevalence in PC3M cancer cells at submicromolar concentrations without affecting cell viability. Structure–activity relationship exploration of the structural elements necessary for activity resulted in the discovery of several potent compounds. Analysis of in vitro drug-like properties led to the discovery of the bioavailable analogue, metarrestin, which has shown potent antimetastatic activity with improved survival in rodent models and is currently being evaluated in a first-in-human phase 1 clinical trial
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