Enhance wine production potential by using fresh and dried red grape and blueberry mixtures with different yeast strains for fermentation

Red grapes and blueberries are known for their high content of bioactive compounds and antioxidant properties. In Mediterranean winemaking, traditional sun-drying can be replaced by controlled-airflow-chamber-drying, which provides better quality, higher phenolic content, and increased antioxidants. This study aimed to increase the sugar content and phenolic compounds of the must by drying the fruits to fifty per cent of their original moisture content. Two musts were prepared: the first one was prepared by combining fresh red grapes and dried blueberries (M1), while the other was created using dried red grapes and fresh blueberries (M2), followed by fermentation at 25 °C with M05 Mead and X5 yeast strains. The M2 must showed the highest levels of phenolic compounds, red color (A520), total anthocyanins, and antioxidant activity. During fermentation, the anthocyanin content increased mainly in the dried blueberry macerates, where it increased between 4- to 5.5-fold. More bioactive compounds were extracted from the wines produced using yeast inoculation despite the shorter maceration times. A sensory analysis demonstrated consumers’ acceptance of the wines in terms of color, flavor, and aroma. In conclusion, the use of red grapes in the production of blueberry red wine proved to be effective, providing higher sugar and must yields, while the dried fruits improved the fermentable sugar content obtaining wines with an alcoholic content between 10 and 11% (v/v). The higher levels of bioactive compounds increased the antioxidant capacity of the resulting red fruit wines

Identificación de competencias y características deseables en el profesorado de ciencias de EGB

This article offers the vision held by some groups of teachers on various qualities taken as important for a Science Teacher of Primary Education, as well as the opinion on to what extend those qualities are found in this type of teachers

Esters of Cinnamic Acid as Green Plasticizers for Polylactide Formulations with Improved Ductility

[EN] This study demonstrates the potential of different cinnamate esters, namely methyl trans-cinnamate (MC), isobutyl cinnamate (IBC), allyl cinnamate (AC), and ethyl cinnamate (EC), as environmentally friendly plasticizers for polylactide (PLA). Plasticized PLA formulations with a constant nominal wt% of 20 of each plasticizer are compounded in a twin-screw co-rotating extruder and subsequently processed by injection molding. The results show exceptional plasticization efficiency of AC with an increase in elongation at break from 3.9% (neat PLA), up to 339.4% and a remarkable increase in impact strength, thus showing great potential to overcome the main drawback related to PLA intrinsic brittleness. The incorporation of cinnamates in a PLA matrix leads to a decrease in Tg from 61.7 °C down to 36.1 °C for the plasticized PLA formulation containing 20 wt% AC. Thermogravimetry analysis reveals that a slight plasticizer loss occurs during processing, as it happens with other monomeric plasticizers, but this phenomenon does not limit their plasticization efficiency. Therefore, the results obtained in this study confirm the suitability of a new family of organic compounds derived from the esterification of cinnamic acid as green plasticizers for PLA with improved toughness, with comparable, or even superior, ductile properties of typical plasticizers for PLA.This research is a part of the grant PID2020-116496RB-C22, funded by MCIN/AEI/10.13039/501100011033 and the grant TED2021-131762A-I00, funded by MCIN/AEI/10.13039/501100011033 and by the European Union "NextGenerationEU"/PRTR. Authors also thank Generalitat Valenciana-GVA for funding this research through the grant numbers AICO/2021/025 and CIGE/2021/094. Funding for open access charge: Universitat Politecnica de Valencia. Funded with Aid for First Research Projects (PAID-06-22), Vice-rectorate for Research of the Universitat Politecnica de Valencia (UPV). JaumeGomez-Caturla wants to thank Generalitat Valenciana-GVA, for his FPI grant(ACIF/2021/185) and grant FPU20/01732 funded by MCIN/AEI/10.13039/501100011033 and by ESF Investing in your future. Juan Ivorra-Martinez wants to thank FPU19/01759 grant funded by MCIN/AEI/10.13039/501100011033 and by ESF Investing in your future. Virginia Moreno wants to thank Generalitat Valenciana-GVA for funding a postdoc position through the APOSTD program co-funded by ESF Investing in your future, grant number CIAPOS/2021/67. D. Lascano acknowledge the Margarita Salas postdoctoral grant from the Ministerio de Universidades, Spain, funded by the European Union-Next Generation EU. Microscopy Services at UPV are also acknowledged by their help in collecting and analyzing images. Open access funding provided by Universitat Politecnica de Valencia within the CRUE/UNIRIS gold Agreement.Barandiaran, A.; Gómez-Caturla, J.; Ivorra-Martinez, J.; Lascano-Aimacaña, DS.; Sellés, M.; Moreno-García, V.; Fenollar, O. (2023). Esters of Cinnamic Acid as Green Plasticizers for Polylactide Formulations with Improved Ductility. Macromolecular Materials and Engineering. 308(8). https://doi.org/10.1002/mame.202300022308

Electrodes based on nafion and epoxy-graphene composites for improving the performance and durability of open cathode fuel cells, prepared by electrospray deposition

Fabrication of electrodes for polymer electrolyte fuel cells is a intriguing process in which a balance between gas transport, electrical conductivity, proton transport and water managing must be optimized. In this work four different electrodes prepared by electrospray deposition have been studied using different catalytic inks, in which Nafion and epoxy doped with Graphene-Nanoplatelets were used as binders. After studying the behavior of those electrodes in a single open cathode fuel cell proton electrolyte membrane, it is clear that the addition of epoxy as binder doped with graphene, improves the performance of the fuel cell and increase the mechanical stability of the electrode avoiding the loose of catalyst during the electrode manipulation in the fuel cell assembly process and the durability of the fuel cell. To explain this behavior, an ex-situ study was carried out, in which properties such as its surface morphology, hydrophobicity and electrical and thermal conductivity of those electrodes were studied. From the results of this study, such improvement in the performance of the fuel cell was justified on the basis of the increase in the electrical conductivity, a diminution in its thermal conductivity and an enhancement of hydrophobicity (surface morphology) of the deposited catalyst layer, when an optimum quantity of epoxy is added to the catalytic ink that makes to improve the mechanical properties of those electrodesAJN and MAG are actually working on this project with a contract funded by the Comunidad Atonoma de la Región de Murcia, Conserjería de Desarrollo Económico, Turismo y Empleo, and the European Union, through the program RIS3- MUR, grant number 2I20SAE00079. This work has also been funded by the Spanish Ministry of Science and Innovation (AEI, Spain,PID2020-112744GB-I00/AEI/10.13039/501100011033 and RTI2018-095844-B-I00), Fundacion Seneca (Región de Murcia, Spain), grant number: 20985/PI/18 and Agencia estatal española de Investigación, grant number PID2019-104272RBC55/AEI/10.13039/501100011033. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

Rotura del tendón distal del bíceps braquial

Objetivo: presentar nuestra experiencia en el tratamiento de las roturas del tendón del bíceps braquial en trabajadores manuales. Material y métodos: Hemos intervenido a 9 pacientes con una edad media de 47 años, realizando en 8 ocasiones una reinserción transósea del tendón en la tuberosidad bicipital del radio por medio de una doble vía de abordaje. El seguimiento medio ha sido de 13 meses. Resultados: fueron excelentes, recuperando en todos los casos la fuerza muscular previa y una movilidad media final completa para la flexión y extensión, 85º de supinación y 86º de pronación. Todos se han reincorporado a su puesto de trabajo en un período entre los 3 y 4 meses. Conclusiones: Esta técnica se ha mostrado muy eficaz en el tratamiento de este tipo de patología, recomendándose siempre la cirugía en pacientes activos.Objective: to present our experience in the treatment of ruptures of the distal biceps braquialis tendon in hand workers. Methods: 9 patients, middle age 47, went under surgery, 8 of them with a transoseus reinsertion of the tendon in the bicipital tuberosity of the radius with a double surgical approach. The average follow-up was 13 months. Results: excellent results were achieved in all of the 9 patients, recovering previous muscle strength, with full range of flexion-extension, 85º of supination and 86º of pronation. All 9 patients return to work in a period of 3 to 4 months. Conclusion: this technique is effective in the treatment of this injury, and it is recommended in active patients

Estrategias de aprendizaje basadas en la modelización matemática en Educación Secundaria Obligatoria

En este trabajo presentamos una experiencia llevada a cabo en el Instituto de Educación Secundaria de la Población de Moixent durante el curso 2009-2010. En el trabajo se presentan una serie de herramientas diseñadas para la implantación de la modelización matemática en el aula como una herramienta didáctica más que ayude a la consecución de los objetivos de la etapa y la adquisición de competencias. Se analiza en detalle la adecuación del material diseñado y se establecen unas conclusiones generales que nos permitirán en este curso la realización de la experiencia de forma más ampliaPeer ReviewedPostprint (published version

Use of metalloproteomics to access environmental stress in the free-living mice mus spretus

Comunicaciones a congreso

D-Fagomine lowers postprandial blood glucose and modulates bacterial adhesion

d-Fagomine is an iminosugar originally isolated from seeds of buckwheat (Fagopyrum sculentum Moench), present in the human diet and now available as a pure crystalline product. We tested d-fagomine for activities connected to a reduction in the risk of developing insulin resistance, becoming overweight and suffering from an excess of potentially pathogenic bacteria. The activities were: intestinal sucrase inhibition in vitro (rat mucosa and everted intestine sleeves), modulation of postprandial blood glucose in rats, bacterial agglutination and bacterial adhesion to pig intestinal mucosa. When ingested together with sucrose or starch, d-fagomine lowered blood glucose in a dose-dependent manner without stimulating insulin secretion. d-Fagomine reduced the area under the curve (0-120 min) by 20 % (P < 0•01) and shifted the time to maximum blood glucose concentration (T max) by 15 min at doses of 1-2 mg/kg body weight when administered together with 1 g sucrose/kg body weight. Moreover, d-fagomine (0•14 mm) agglutinated 60 % of Enterobacteriaceae (Escherichia coli, Salmonella enterica serovar Typhimurium) populations (P < 0•01), while it did not show this effect on Bifidobacterium spp. or Lactobacillus spp. At the same concentration, d-fagomine significantly (P < 0•001) inhibited the adhesion of Enterobacteriaceae (95-99 % cells in the supernatant) and promoted the adhesion of Lactobacillus acidophilus (56 % cells in the supernatant) to intestinal mucosa. d-Fagomine did not show any effect on bacterial cell viability. Based on all this evidence, d-fagomine may be used as a dietary ingredient or functional food component to reduce the health risks associated with an excessive intake of fast-digestible carbohydrates, or an excess of potentially pathogenic bacteria. © 2011 The Authors

Preanalytical issues related to routine and diagnostic glucose tests: Results from a survey in Spain

Introduction: Diabetes mellitus (DM) is one of the most prevalent diseases worldwide. The objective of this study was to find out under what preanalytical conditions routine and diagnostic glucose tests are performed across Spanish laboratories; and also what criteria are used for DM diagnosis. Materials and methods: An online survey was performed by the Commission on Quality Assurance in the Extra-Analytical Phase of the Spanish Society of Laboratory Medicine (SEQC-ML). Access to the questionnaire was available on the home page of the SEQC-ML website during the period April-July 2018. Data analysis was conducted with the IBM SPSS© Statistics (version 20.0) program. Results: A total of 96 valid surveys were obtained. Most laboratories were in public ownership, serving hospital and primary care patients, with high and medium workloads, and a predominance of mixed routine-urgent glucose testing. Serum tubes were the most used for routine glucose analysis (92%) and DM diagnosis (54%); followed by lithium-heparin plasma tubes (62%), intended primarily for urgent glucose testing; point-ofcare testing devices were used by 37%; and plasma tubes with a glycolysis inhibitor, mainly sodium fluoride, by 19%. Laboratories used the cut-off values and criteria recognized worldwide for DM diagnosis in adults and glucose-impaired tolerance, but diverged in terms of fasting plasma glucose and gestational DM criteria. Conclusion: Preanalytical processing of routine and DM diagnostic glucose testing in Spain does not allow a significant, non-quantified influence of glycolysis on the results to be ruled out. Possible adverse consequences include a delay in diagnosis and possible under-treatmen

Tratado de derechos reales. Tomo II Propiedad y posesión

La presente investigación está referida al análisis de los dos principales derechos reales: la posesión y la propiedad, y es la continuación de la investigación concluida denominada Tratado de derechos reales, tomo I, teoría de los bienes y los derechos reales. Esta parte de la investigación corresponde al desarrollo de dos de sus principales instituciones. Así, se comienza con el análisis sociojurídico de la posesión (poder hecho) como derecho transitorio (temporal y momentáneo), para luego entrar al desarrollo de la propiedad (poder de derecho) como derecho definitivo (permanente y total), ambas instituciones reconocidas como situaciones jurídicas de gran trascendencia en las relaciones jurídicas patrimoniales, protegidas por la ley a través de mecanismos de defensa