10 research outputs found

    Propagation of Cylindrical Vector Laser Beams in Turbid Tissue-Like Scattering Media

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    We explore the propagation of the cylindrical vector beams (CVB) in turbid tissue-like scattering medium in comparison with the conventional Gaussian laser beam. The study of propagation of CVB and Gaussian laser beams in the medium is performed utilizing the unified electric field Monte Carlo model. The implemented Monte Carlo model is a part of a generalized on-line computational tool and utilizes parallel computing, executed on the NVIDIA Graphics Processing Units (GPUs) supporting Compute Unified Device Architecture (CUDA). Using extensive computational studies, we demonstrate that after propagation through the turbid tissue-like scattering medium, the degree of fringe contrast for CVB becomes at least twice higher in comparison to the conventional linearly polarized Gaussian beam. The results of simulations agree with the results of experimental studies. Both experimental and theoretical results suggest that there is a high potential of the application of CVB in the diagnosis of biological tissues

    Controlling the dynamics of colloidal particles by critical Casimir forces

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    Critical Casimir forces can play an important role for applications in nano-science and nano-technology, owing to their piconewton strength, nanometric action range, fine tunability as a function of temperature, and exquisite dependence on the surface properties of the involved objects. Here, we investigate the effects of critical Casimir forces on the free dynamics of a pair of colloidal particles dispersed in the bulk of a near-critical binary liquid solvent, using blinking optical tweezers. In particular, we measure the time evolution of the distance between the two colloids to determine their relative diffusion and drift velocity. Furthermore, we show how critical Casimir forces change the dynamic properties of this two-colloid system by studying the temperature dependence of the distribution of the so-called first-passage time, i. e., of the time necessary for the particles to reach for the first time a certain separation, starting from an initially assigned one. These data are in good agreement with theoretical results obtained from Monte Carlo simulations and Langevin dynamics

    Correction: Controlling the dynamics of colloidal particles by critical Casimir forces.

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    Correction for 'Controlling the dynamics of colloidal particles by critical Casimir forces' by Alessandro Magazzù et al., Soft Matter, 2019, 15, 2152–2162, DOI: 10.1039/C8SM01376D

    Effect of double or single bonding in C–H stretching signal propagation in organic molecules. A computational study

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    © 2018The objective of this study is to evaluate vibrational energy propagation of a C–H stretching signal on unsaturated organic molecules and the effect of saturation in a specific site of those molecules using ab-initio molecular dynamic relaxation simulations. The results show that the inclusion of saturation at a specific site at the double bonded organic chain blockade the protrusion of C–H stretching vibrational energy at this site. As the saturation involves the change from double to single bonding regime, the effect is possibly originated by the loss of electron resonance at this specific site

    Flickering of fetal erythrocytes membrane under gestational diabetes observed with dual time resolved membrane fluctuation spectroscopy

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    The membrane flickering of human fetal red blood cells (RBCs) affected by gestational diabetes mellitus (GDM) was studied with dual time resolved membrane fluctuation spectroscopy (D-TRMFS). This new technique is a modified version of the dual optical tweezers method that has been adapted to measure the mechanical properties of RBCs at two distant membrane points simultaneously. The micro-rheological parameters were obtained from direct membrane flickering measurements, followed by Fourier decomposition and cell membrane model adjustment. Our results show a significant decrease of 6.01 ± 1.19 nm in membrane fluctuations amplitude in healthy fetal, compared with healthy adult RBCs, meanwhile the amplitude in GDM cells increased 3.22 ± 1.10 nm compared with healthy fetal RBCs. Between GDM and healthy fetal RBCs, there are significant differences, especially in the bending modulus. Considering the mean of the two membrane points measured, the tension for GDM RBCs increased by 6.431 ± 3.57 (10−7 [N/m]) compared with healthy fetal RBCs, meanwhile, the bending was increased by 2.483 ± 0.58 (10−19 [J]) in GDM compared with healthy fetal RBCs. These results showed significant increment of 1.23 ± 0.07-fold and 3.29 ± 0.36-fold in tension and bending modulus in GDM, respectively. The strong impact of GDM on bending modulus could be associated with oxidative stress and lipid peroxidation, previously reported in fetal plasma of GDM cases

    Asymmetrical vibrational energy propagation through double or single bonds of small organic molecules. An ab-initio molecular dynamics study

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    The present study evaluates the vibrational energy propagation from an O[dbnd]C stretching through the double or single bonds of two small carboxamide molecules. The results show that double bonding facilitates vibrational energy flow while single bonding blockades energy protrusion. Similarly, the direct injection of vibrational energy at a single bond precludes the dissipation of vibrational energy to the rest of the molecular structure generating a vibrational trapping effect. Correlation between bond oscillations and molecular orbital energy fluctuation are analyzed. The presence or absence of those correlations seems to be determinant for vibrational energy flow at the molecular scale

    Hyperspectral Microscopy Technology to Detect Syrups Adulteration of Endemic Guindo Santo and Quillay Honey Using Machine-Learning Tools

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    Honey adulteration is a common practice that affects food quality and sale prices, and certifying the origin of the honey using non-destructive methods is critical. Guindo Santo and Quillay are fundamental for the honey production of Biobío and the Ñuble region in Chile. Furthermore, Guindo Santo only exists in this area of the world. Therefore, certifying honey of this species is crucial for beekeeper communities—mostly natives—to give them advantages and competitiveness in the global market. To solve this necessity, we present a system for detecting adulterated endemic honey that combines different artificial intelligence networks with a confocal optical microscope and a tunable optical filter for hyperspectral data acquisition. Honey samples artificially adulterated with syrups at concentrations undetectable to the naked eye were used for validating different artificial intelligence models. Comparing Linear discriminant analysis (LDA), Support vector machine (SVM), and Neural Network (NN), we reach the best average accuracy value with SVM of 93% for all classes in both kinds of honey. We hope these results will be the starting point of a method for honey certification in Chile in an automated way and with high precision
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