Sustainable tourism strategies in the spanish cittaslow

El turismo tiene una enorme capacidad para generar crecimiento económico y dinamizar el mercado laboral, siendo uno de sus principales retos actuales, contribuir al desarrollo sostenible. El enfoque de la filosofía slow propugna el turismo slow como forma de vida y de consumo responsable y sostenible, y la red cittaslow española ha adoptado dicho planteamiento. El objetivo de esta investigación es analizar el avance en el cumplimiento de los principios del turismo slow en la red cittaslow en España. La metodología aplicada consiste en analizar comparativamente las actuaciones de oferta turística que divulgan las web oficiales de los ayuntamientos de las cittaslow españolas, a la luz de principios del turismo slow. Los hallazgos muestran que los 12 municipios que se han registrado en la red de cittaslow en España tienen relevancia en patrimonio histórico y recursos naturales, pero sólo un 30% aprovecha la singularidad de ser una cittaslow, para impulsar su turismo, de forma sistemática. La publicación de sus indicadores cittaslow podría acelerar los avances.Tourism has an enormous capacity to generate economic growth and boost the labor market, but contributing to sustainable development is one of the main challenges today. The slow philosophy approach advocates slow tourism as a responsible and sustainable way of life and consumption, and the Spanish Cittaslow network has adopted this approach. The objective of this research is to analyze progress in compliance with the principles of slow tourism in the Spanish Cittaslow network. The applied methodology consists of a comparative analysis of the tourism offerings communicated on the official websites of the Spanish Cittaslow municipalities, in light of slow tourism principles. The findings show that the 12 municipalities that have registered in the Citta Slow network in Spain are relevant in terms of historical heritage and natural resources, but only 30% take advantage of the uniqueness of being a Cittaslow to systematically promote their tourism. Publication of its Cittaslow indicators could accelerate progres

Low-Cost Materials for Do-It-Yourself (DIY) Installation of House Screening against <em>Aedes aegypti</em>

House-screening (HS) using fixed-aluminium frames to reduce the risk of indoor infestation with Aedes aegypti mosquitoes as well as the risk of Aedes-transmitted diseases in communities living in endemic areas. However, the success of this approach has been hindered by the elevated cost of the aluminium-based materials as well as their professional installation, which cannot be afforded by people living under vulnerable conditions. Cost-saving strategies such as the use of low-cost materials including wood, PVC, and Velcro are within the list of HS options available and offered by HS businesses and/or Do-it-yourself (DIY) packages verbi gratia ready-made and ready-to-install mosquito-screens. Here, we evaluated the efficacy of low-cost frames constructed with different materials to protect against Ae. aegypti indoor infestation using experimental huts. The efficacy of protection in preventing female mosquito passing inside the huts of any of the options of frames was high (>93%) compared to the control with no-screen. People’s perceptions on the different materials showed the most “popular” alternative was the frame made of wood (62%). All the prototype-frames of HS made of different materials were effective at blocking Ae. aegypti entering-mosquitoes particularly, low-cost options like magnets and Velcro

FSR 1716: A New Milky Way Globular Cluster Confirmed Using VVV RR Lyrae Stars

We use deep multi-epoch near-IR images of the VISTA Variables in the Vía Láctea (VVV) Survey to search for RR Lyrae stars toward the Southern Galactic plane. Here, we report the discovery of a group of RR Lyrae stars close together in VVV tile d025. Inspection of the VVV images and PSF photometry reveals that most of these stars are likely to belong to a globular cluster that matches the position of the previously known star cluster FSR 1716. The stellar density map of the field yields a >100? detection for this candidate globular cluster that is centered at equatorial coordinates R.A. J2000 = 16:10:30.0, decl. J2000 = ?53:44:56 and galactic coordinates l = 329.77812, b = ?1.59227. The color–magnitude diagram of this object reveals a well-populated red giant branch, with a prominent red clump at K s = 13.35 ± 0.05, and J ? K s = 1.30 ± 0.05. We present the cluster RR Lyrae positions, magnitudes, colors, periods, and amplitudes. The presence of RR Lyrae indicates an old globular cluster, with an age >10 Gyr. We classify this object as an Oosterhoff type I globular cluster, based on the mean period of its RR Lyrae type ab, $\langle P\rangle =0.540$ days, and argue that this is a relatively metal-poor cluster with [Fe/H] = ?1.5 ± 0.4 dex. The mean extinction and reddening for this cluster are ${A}_{{K}_{s}}=0.38\pm 0.02$ and E(J ? K s ) = 0.72 ± 0.02 mag, respectively, as measured from the RR Lyrae colors and the near-IR color–magnitude diagram. We also measure the cluster distance using the RR Lyrae type ab stars. The cluster mean distance modulus is (m ? M)0 = 14.38 ± 0.03 mag, implying a distance D = 7.5 ± 0.2 kpc and a Galactocentric distance R G = 4.3 kpc

Olbiogaster Osten Sacken (Diptera: Anisopodidae) from Mexico, with the description of three new species

Huerta, Heron, Dzul-Manzanilla, Felipe, Navarrete-Carballo, Juan C., Manrique-Saide, Pablo, Hancock, E. Geoffrey (2019): Olbiogaster Osten Sacken (Diptera: Anisopodidae) from Mexico, with the description of three new species. Zootaxa 4565 (4): 475-492, DOI: 10.11646/zootaxa.4565.4.

FIGURE 3 in Olbiogaster Osten Sacken (Diptera: Anisopodidae) from Mexico, with the description of three new species

FIGURE 3. Olbiogaster nuxco sp. nov. Male paratype, A. dorsal view; B. lateral view; C. Legs, top: hind leg, middle: midleg, lower: foreleg, lateral view; D. Abdomen and wing, dorsal view. Scale bar= 1.0 mm

Pharmacological management of antifungal agents in pulmonary aspergillosis: an updated review

Introduction: Aspergillus may cause different types of lung infections: invasive, chronic pulmonary or allergic bronchopulmonary aspergillosis. Pharmacological management with antifungals poses as a challenge. Patients diagnosed with pulmonary aspergillosis are complex, as well as the problems associated with antifungal agents. Areas covered: This article reviews the pharmacology of antifungal agents in development and currently used to treat pulmonary aspergillosis, including the mechanisms of action, pharmacokinetics, pharmacodynamics, dosing, therapeutic drug monitoring and safety. Recommendations to manage situations that arise in daily clinical practice are provided. A literature search of PubMed was conducted on November 15th, 2020 and updated on March 30th, 2021. Expert opinion: Recent and relevant developments in the treatment of pulmonary aspergillosis have taken place. Novel antifungals with new mechanisms of action that extend antifungal spectrum and improve pharmacokinetic-related aspects, drug-drug interactions and safety are under current study. For those antifungals already marketed, new data related to pharmacokinetics, pharmacodynamics, dose adjustments in special situations, therapeutic drug monitoring and safety are available. To maximize efficacy and reduce the risk of associated toxicities, it is essential to choose the most appropriate antifungal; optimize its dose, interval, route of administration and length of treatment; and prevent side effects

Tratamientos Psicológicos Empíricamente Apoyados Para la Infancia y Adolescencia: : Estado de la Cuestión

Background: The empirical evidence accumulated on the effi cacy, effectiveness, and effi ciency of psychotherapeutic treatments in children and adolescents calls for an update. The main goal of this paper objective was to carry out a selective review of empirically supported psychological treatments for a variety of common psychological disorders and problems in childhood and adolescence. Method: A review was carried out of the psychological treatments for different psychological disorders and problems in socialemotional or behavioral adjustment in the child-adolescent population according to the Spanish National Health System (Clinical Practice Guidelines) levels of evidence and degrees of recommendation. Results: The fi ndings suggest that psychological treatments have empirical support for addressing a wide range of psychological problems in these developmental stages. The degree of empirical support ranges from low to high depending on the phenomenon analyzed. The review suggests unequal progress in the different fi elds of intervention. Conclusions: From this update, psychologists will be able to make informed decisions when implementing those empirically supported treatments to address the problems that occur in childhood and adolescence.Antecedentes: la evidencia empírica acumulada en los últimos años sobre la efi cacia, efectividad y efi ciencia de los tratamientos psicológicos en la infancia y adolescencia reclama una actualización. El principal objetivo de este artículo es el de llevar a cabo una revisión de los tratamientos psicológicos empíricamente apoyados para una diversidad de problemas psicológicos habituales en la infancia y la adolescencia. Método: se revisan los tratamientos psicológicos para diferentes trastornos psicológicos y problemas en el ajuste socioemocional o conductual en población infanto-juvenil en función de los niveles de evidencia y grados de recomendación del Sistema Nacional de Salud de España (Guías de Práctica Clínica). Resultados: los hallazgos sugieren que los tratamientos psicológicos específi camente dirigidos a niños, niñas y adolescentes disponen de apoyo empírico para el abordaje de un amplio elenco de problemas psicológicos. Este grado de apoyo empírico oscila de bajo a alto en función del problema analizado. La revisión muestra un avance desigual en los diferentes campos de intervención. Conclusiones: a partir de esta actualización, los profesionales de la psicología podrán tomar decisiones informadas a la hora de implementar aquellas intervenciones psicológicas con apoyo empírico para el abordaje de los problemas en la infancia y la adolescenci

Primer consenso interinstitucional de neoplasias mieloproliferativas crónicas

Objetivo: El objetivo del consenso es poner a disposición de los profesionales de las diferentes instituciones de salud pública en nuestro país, quienes se encuentran a cargo de estas enfermedades, la información más relevante y actualizada acerca de su diagnóstico y tratamiento en la práctica clínica. Con este consenso interinstitucional esperamos contribuir a mejorar la calidad de la atención de los pacientes con neoplasias mieloproliferativas crónicas a todo lo ancho y largo de la República Mexicana, con el fin de unificar criterios tanto en diagnóstico como en tratamiento de las diferentes enfermedades mieloproliferativas

Riesgo en los procedimientos invasivos

Los pacientes con neoplasias mieloproliferativas tienen un riesgo incrementado de trombosis y sangrado. Se debe identificar dicho riesgo, así como individualizar la estrategia terapéutica previo a los procedimientos invasivos; una adecuada citorreducción disminuye el riesgo de complicaciones

Trasplante de progenitores hematopoyéticos en la mielofibrosis

El objetivo de este trabajo es generar recomendaciones sobre el manejo del trasplante alogénico de células madre (alo-SCT) en la mielofibrosis primaria (MFP). Se utilizó una revisión sistemática integral de artículos publicados entre 1999 y 2015 (enero) como fuente de evidencia científica. Las recomendaciones se produjeron mediante un proceso Delphi en el que participó un panel de 23 expertos designados por la European LeukemiaNet y el European Blood and Marrow Transplantation Group. Las preguntas clave incluyeron la selección de pacientes, la selección de donantes, el manejo previo al trasplante, el régimen de acondicionamiento, el manejo posterior al trasplante, la prevención y el manejo de la recaída después del trasplante. Los pacientes con enfermedad de riesgo intermedio 2 o alto y edad 2%, o citogenética adversa. La esplenectomía previa al trasplante debe decidirse caso por caso. Los pacientes con enfermedad de riesgo intermedio 2 o alto que carecen de un hermano compatible con el antígeno leucocitario humano (HLA) o de un donante no emparentado deben inscribirse en un protocolo que utilice donantes no idénticos de HLA. PB se consideró la fuente más apropiada de células madre hematopoyéticas para trasplantes de hermanos y donantes no emparentados compatibles con HLA. La intensidad óptima del régimen de acondicionamiento aún debe definirse. Se consideraron adecuadas estrategias como la suspensión de los fármacos inmunosupresores, la infusión de linfocitos del donante o ambas para evitar la recaída clínica. En conclusión, proporcionamos recomendaciones basadas en consenso destinadas a optimizar el alo-SCT en MFP. Se destacaron las necesidades clínicas insatisfechas