Seismic velocity determination in gravel and sands using piezocrystals

The exact determination of seismic waves' propagation velocities has great importance in the geotechnics due to from that it is possible to determine, among other parameters, the dynamic ones: Elasticity E, Rigidity G, Poisson !, compressibility B; as well as to reach a knowledge on the stress-strain behavior for the studied soil samples. The seismic waves transmission considered in tests at laboratory scale carried out in the present work is a phenomenon that produces very small deformation, and so doesn't disturb the material. This allowsto apply the results in a more general scale to study the behavior of soils in situ and to predict their answer to stress.With the purpose to study the response of particulate material subjected to seismic excitements at small scale, samples of gravels and sands were successively introduced in an odometric cell, exciting them with impulsive signals and registering the corresponding seismograms through general purpose piezoelectric transducers embedded in ends of the cell.The distance source-receiver was interval increased, which enabled, from the corresponding regression straight lines, to calculate in precise form the propagation velocities (for P waves).The tests were carried out in samples of dry alluvial soil with three different grain sizes. The respective frequency spectra of the signals were determined for two packing modes: loose and compact, what added information on the medium characteristics

Dossier. Estudios de códices mesoamericanos en Europa

Sin resume

Normal-Fat vs. High-Fat Diets and Olive Oil vs. CLA-Rich Dairy Fat: A Comparative Study of Their Effects on Atherosclerosis in Male Golden Syrian Hamsters

The relationship between milk fat intake (because of its high saturated fatty acid content) and the risk of suffering from cardiovascular diseases remains controversial. Thus, Golden Syrian hamsters were fed two types of fat—sheep milk fat that was rich in rumenic (cis9,trans11-18:2) and vaccenic (trans11-18:1) acids and olive oil—and two doses (a high- or normal-fat diet) for 14 weeks, and markers of lipid metabolism and atherosclerosis evolution were analyzed. The results revealed that the type and percentage of fat affected most plasma biochemical parameters related to lipid metabolism, while only the expression of five (CD36, SR-B1, ACAT, LDLR, and HMG-CoAR) of the studied lipid-metabolism-related genes was affected by these factors. According to aortic histology, when ingested in excess, both fats caused a similar increase in the thickness of fatty streaks, but the high-milk-fat-based diet caused a more atherogenic plasma profile. The compositions of the fats that were used, the results that were obtained, and the scientific literature indicated that the rumenic acid present in milk fat would regulate the expression of genes involved in ROS generation and, thus, protect against LDL oxidation, causing an effect similar to that of olive oil.This research was funded by the Basque Government (Grant to Research Groups IT944-16). A.B. and G.S.-G. received a research grant from the University of the Basque Country (calls 2009 and 2019, respectively)

Borderline personality traits mediate the relationship between low perceived social support and non-suicidal self-injury in a clinical sample of adolescents

Altres ajuts: Acord transformatiu CRUE-CSICNon-suicidal self-injury (NSSI) is a serious public health concern among adolescents, especially in clinical settings. Social support plays a critical role in the onset and maintenance of NSSI in adolescence. NSSI is closely associated with borderline personality disorder (BPD), yet no previous work has analyzed the mediating role of borderline traits in the relationship between perceived social support (PSS) and NSSI. This study aimed to address this gap

Measurement of forward Z → e+e− production s√s=8 TeV

A measurement of the cross-section for Z-boson production in the forward region of pp collisions at 8 TeV centre-of-mass energy is presented. The measurement is based on a sample of Z → e+e− decays reconstructed using the LHCb detector, corresponding to an integrated luminosity of 2.0 fb−1. The acceptance is defined by the requirements 2.0 20 GeV for the pseudorapidities and transverse momenta of the leptons. Their invariant mass is required to lie in the range 60-120 GeV. The cross-section is determined to beS

Measurement of indirect CP asymmetries in D0 → K−K+ and D0 → π−π+ decays using semileptonic B decays

Time-dependent CP asymmetries in the decay rates of the singly Cabibbo-suppressed decays D0 → K−K+ and D0 → π−π+ are measured in pp collision data corresponding to an integrated luminosity of 3.0 fb−1 collected by the LHCb experiment. The D0 mesons are produced in semileptonic b-hadron decays, where the charge of the accompanying muon is used to determine the initial state as D0 or D¯0. The asymmetries in effective lifetimes between D0 and D¯0 decays, which are sensitive to indirect CP violation, are determined to be AΓ(K−K+)=(−0.134±0.077−0.026−0.034)%,AΓ(π−π+)=(−0.092±0.145−0.025−0.033)%, where the first uncertainties are statistical and the second systematic. This result is in agreement with previous measurements and with the hypothesis of no indirect CP violation in D0 decays.S

Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

BACKGROUND: Early life is a period of drastic epigenetic remodeling in which the epigenome is especially sensitive to extrinsic and intrinsic influence. However, the epigenome-wide dynamics of the DNA methylation changes that occur during this period have not been sufficiently characterized in longitudinal studies. METHODS: To this end, we studied the DNA methylation status of more than 750,000 CpG sites using Illumina MethylationEPIC arrays on 33 paired blood samples from 11 subjects at birth and at 5 and 10 years of age, then characterized the chromatin context associated with these loci by integrating our data with histone, chromatin-state and enhancer-element external datasets, and, finally, validated our results through bisulfite pyrosequencing in two independent longitudinal cohorts of 18 additional subjects. RESULTS: We found abundant DNA methylation changes (110,726 CpG sites) during the first lustrum of life, while far fewer alterations were observed in the subsequent 5 years (460 CpG sites). However, our analysis revealed persistent DNA methylation changes at 240 CpG sites, indicating that there are genomic locations of considerable epigenetic change beyond immediate birth. The chromatin context of hypermethylation changes was associated with repressive genomic locations and genes with developmental and cell signaling functions, while hypomethylation changes were linked to enhancer regions and genes with immunological and mRNA and protein metabolism functions. Significantly, our results show that genes that suffer simultaneous hyper- and hypomethylation are functionally distinct from exclusively hyper- or hypomethylated genes, and that enhancer-associated methylation is different in hyper- and hypomethylation scenarios, with hypomethylation being more associated to epigenetic changes at blood tissue-specific enhancer elements. CONCLUSIONS: These data show that epigenetic remodeling is dramatically reduced after the first 5 years of life. However, there are certain loci which continue to manifest DNA methylation changes, pointing towards a possible functionality beyond early development. Furthermore, our results deepen the understanding of the genomic context associated to hyper- or hypomethylation alterations during time, suggesting that hypomethylation of blood tissue-specific enhancer elements could be of importance in the establishment of functional states in blood tissue during early-life

Precise measurements of the properties of the B1(5721)0,+ and B *2(5747)0,+ states and observation of B+,0π−,+ mass structures

Invariant mass distributions of B+π− and B0π+ combinations are investigated in order to study excited B mesons. The analysis is based on a data sample corresponding to 3.0 fb−1 of pp collision data, recorded by the LHCb detector at centre-of-mass energies of 7 and 8 TeV. Precise measurements of the masses and widths of the B1(5721)0,+ and B2(5747)0,+ states are reported. Clear enhancements, particularly prominent at high pion transverse momentum, are seen over background in the mass range 5850-6000 MeV in both B+π− and B0π+ combinations. The structures are consistent with the presence of four excited B mesons, labelled B J (5840)0,+ and B J (5960)0,+, whose masses and widths are obtained under different hypotheses for their quantum numbersS

Measurement of CP asymmetries and polarisation fractions in B0s→K∗0K¯∗0 decays

An angular analysis of the decay B0s→K∗0K¯∗0 is performed using pp collisions corresponding to an integrated luminosity of 1.0 fb−1 collected by the LHCb experiment at a centre-of-mass energy s√=7 TeV. A combined angular and mass analysis separates six helicity amplitudes and allows the measurement of the longitudinal polarisation fraction f L = 0.201 ± 0.057 (stat.) ± 0.040 (syst.) for the B0s→K∗(892)0K¯∗(892)0 decay. A large scalar contribution from the K ∗0(1430) and K ∗0(800) resonances is found, allowing the determination of additional CP asymmetries. Triple product and direct CP asymmetries are determined to be compatible with the Standard Model expectations. The branching fraction B(Bs→K∗(892)0K¯∗(892)0) is measured to be (10.8 ± 2.1 (stat.) ± 1.4 (syst.) ± 0.6 (f d /f s )) × 10−6.S