Striving to Become a Better Teacher: Linking Teacher Emotions With Informal Teacher Learning Across the Teaching Career

The importance of informal teacher learning (ITL) to teaching effectiveness and student achievement has been repeatedly demonstrated, but there is limited research into the personal antecedents of ITL. We analyzed the relationships between teacher emotions and participation in five different kinds of ITL activities (learning through media, colleague interaction, stakeholder interaction, student interaction, and individual reflection) among 2,880 primary teachers (85.49% female) with a large range of teaching experience. Regression analysis and structural equation modeling revealed a positive association between enjoyment and engagement in all five ITL activities. Anxiety was found to be negatively related to colleague interaction and self-reflection, and anger was found to be negatively associated with student interaction. Furthermore, anxiety and anger were negatively related to teaching experience, whereas enjoyment was independent from teaching experience. Most ITL activities were positively related to teaching experience, except for stakeholder interaction. Implications for teacher training and intervention programs for in-service teachers are discussed

Eddy-resolving simulation of plankton ecosystem dynamics in the California Current System

Author Posting. © Elsevier B.V., 2006. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Deep Sea Research Part I: Oceanographic Research Papers 53 (2006): 1483-1516, doi:10.1016/j.dsr.2006.06.005.We study the dynamics of the planktonic ecosystem in the coastal upwelling zone within the California Current System using a three-dimensional, eddy-resolving circulation model coupled to an ecosystem/biogeochemistry model. The physical model is based on the Regional Oceanic Modeling System (ROMS), configured at a resolution of 15 km for a domain covering the entire U.S. West Coast, with an embedded child grid covering the central California upwelling region at a resolution of 5 km. The model is forced with monthly mean boundary conditions at the open lateral boundaries as well as at the surface. The ecological/biogeochemical model is nitrogen based, includes single classes for phytoplankton and zooplankton, and considers two detrital pools with different sinking speeds. The model also explicitly simulates a variable chlorophyll-to-carbon ratio. Comparisons of model results with either remote sensing observations (AVHRR, SeaWiFS) or in situ measurements from the CalCOFI program indicate that our model is capable of replicating many of the large-scale, time averaged features of the coastal upwelling system. An exception is the underestimation of the chlorophyll levels in the northern part of the domain, perhaps because of the lack of short-term variations in the forcing from the atmosphere. Another shortcoming is that the modeled thermocline is too diffuse, and that the upward slope of the isolines toward the coast is too small. Detailed time-series comparisons with observations from Monterey Bay reveal similar agreements and discrepancies. We attribute the good agreement between the modeled and observed ecological properties in large part to the accuracy of the physical fields. In turn, many of the discrepancies can be traced back to our use of monthly mean forcing. Analysis of the ecosystem structure and dynamics reveal that the magnitude and pattern of phytoplankton biomass in the nearshore region are determined largely by the balance of growth and zooplankton grazing, while in the offshore region, growth is balanced by mortality. The latter appears to be inconsistent with in situ observations and is a result of our consideration of only one zooplankton size class (mesozooplankton), neglecting the importance of microzooplankton grazing in the offshore region. A comparison of the allocation of nitrogen into the different pools of the ecosystem in the 3-D results with those obtained from a box model configuration of the same ecosystem model reveals that only a few components of the ecosystem reach a local steady-state, i.e. where biological sources and sinks balance each other. The balances for the majority of the components are achieved by local biological source and sink terms balancing the net physical divergence, confirming the importance of the 3-D nature of circulation and mixing in a coastal upwelling system.Most of this work has been made possible by two grants from NASA. Additional support is acknowledged from NSF’s ITR program

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study

Background Early mobilisation (EM) is an intervention that may improve the outcome of critically ill patients. There is limited data on EM in COVID-19 patients and its use during the first pandemic wave. Methods This is a pre-planned subanalysis of the ESICM UNITE-COVID, an international multicenter observational study involving critically ill COVID-19 patients in the ICU between February 15th and May 15th, 2020. We analysed variables associated with the initiation of EM (within 72 h of ICU admission) and explored the impact of EM on mortality, ICU and hospital length of stay, as well as discharge location. Statistical analyses were done using (generalised) linear mixed-effect models and ANOVAs. Results Mobilisation data from 4190 patients from 280 ICUs in 45 countries were analysed. 1114 (26.6%) of these patients received mobilisation within 72 h after ICU admission; 3076 (73.4%) did not. In our analysis of factors associated with EM, mechanical ventilation at admission (OR 0.29; 95% CI 0.25, 0.35; p = 0.001), higher age (OR 0.99; 95% CI 0.98, 1.00; p ≤ 0.001), pre-existing asthma (OR 0.84; 95% CI 0.73, 0.98; p = 0.028), and pre-existing kidney disease (OR 0.84; 95% CI 0.71, 0.99; p = 0.036) were negatively associated with the initiation of EM. EM was associated with a higher chance of being discharged home (OR 1.31; 95% CI 1.08, 1.58; p = 0.007) but was not associated with length of stay in ICU (adj. difference 0.91 days; 95% CI − 0.47, 1.37, p = 0.34) and hospital (adj. difference 1.4 days; 95% CI − 0.62, 2.35, p = 0.24) or mortality (OR 0.88; 95% CI 0.7, 1.09, p = 0.24) when adjusted for covariates. Conclusions Our findings demonstrate that a quarter of COVID-19 patients received EM. There was no association found between EM in COVID-19 patients' ICU and hospital length of stay or mortality. However, EM in COVID-19 patients was associated with increased odds of being discharged home rather than to a care facility. Trial registration ClinicalTrials.gov: NCT04836065 (retrospectively registered April 8th 2021)

DETECTION AND IDENTIFICATION OF MOLECULAR WATER POLLUTANTS BY LASER RAMAN SPECTROSCOPY

Work supported in part by the Office of Water Resources Research, Department of Interior, under the provisions of Public Law 88-379 as Project No. A-015-KY.""Author Institution: Department of Electrical Engineering, University of Kentucky LexingtonThe Raman spectra of the potassium salt of 2,4-dichlorophenoxyacetic acid (24DK) in distilled water was determined from $180 cm^{-1}$ to $1600 cm^{-1}$, A 50 mW He-Ne gas laser (6328 {\AA}) with a multipass 2.5 ml Raman cell and Jarrell-Ash Model 25--300 laser Raman Spectrometer was used to detect the right-angle scattering. Four bands centered at approximately $400 cm^{-1}$, $800 cm^{-1}$, $1100 cm^{-1}$ and $1600 cm^{-1}$ are detectable at 500 ppm. The bands at $400 cm^{-1}$, $800 cm^{-1}$, $1100 cm^{-1}$ have small depolarization rates while the band at $1600 cm^{-1}$, which partly overlaps with the $1650 cm^{-1}$ Raman water band, has a relatively large depolarization ratio. The knowledge of these four bands and their depolarization ratios may serve as a means of detecting 24DK in water

The palaeogeographies of Ephesos (Turkey), its harbours, and the Artemision - a geoarchaeological reconstruction for the timespan 1500-300 BC

This geoarchaeological study deals with the coastline evolution around Ephesos (Western Turkey), as well as the related settlements and harbours from 1500 until 300 BC. It focuses on the vicinity of the Artemision (sanctuary of Artemis) site, with special regard to the sacred precinct (temenos) of the main sanctuary of the city. The results give new insights into (i) the farthest inland extension of the Holocene marine transgression, (ii) the sedimentation rates during the Holocene, and (iii) potential harbour sites adjacent to the Artemision. Vibracores up to a depth of 17 m were analyzed using geochemical and sedimentological as well as micro- and macrofaunal methods. In the area of the (later) Artemision the maximum marine transgression dates to the beginning of the 5th millennium BC. At that time, the sea had transgressed at least 18 km inland up to Belevi. The sedimentation rate was very low (0.4 mm/yr) until the lst millennium BC; by the end of the millennium AD it had accelerated, at times by up to a factor often. This was due to human impact, mainly deforestation, and resulted in a delta advance of the Derbent and Selinus rivers. The first temple of Artemis was built in the 7th century BC with a much smaller size and simpler ground plan than the subsequent large marble temples, the construction of which started in the 6th and 4th centuries BC, respectively. By then, the area of the Artemision had silted up, and the coastline had shifted to the north and west of the temple. Ancient authors mention two harbours at Ephesos in pre-Hellenistic times: the Koressian harbour and the 'sacred harbour'. The latter was most probably located in a small embayment between the Artemision and Ayasoluk hill 150 m to the north of the 6th century BC temple of Artemis. It silted up during the following two centuries and had completely disappeared by around 300 BC. We therefore presume that during the 5th to 4th centuries BC the Koressian harbour, located in a marine embayment on the northern side of Panayirdag, gradually took over the function of the main harbour of Ephesos

Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia

Abstract Dysregulated microRNA (miRNA) expression contributes to the pathogenesis of hematopoietic malignancies, including chronic lymphocytic leukemia (CLL). However, an understanding of the mechanisms that cause aberrant miRNA transcriptional control is lacking. In this study, we comprehensively investigated the role and extent of miRNA epigenetic regulation in CLL. Genome-wide profiling conducted on 24 CLL and 10 healthy B cell samples revealed global DNA methylation patterns upstream of miRNA sequences that distinguished malignant from healthy cells and identified putative miRNA promoters. Integration of DNA methylation and miRNA promoter data led to the identification of 128 recurrent miRNA targets for aberrant promoter DNA methylation. DNA hypomethylation accounted for more than 60% of all aberrant promoter-associated DNA methylation in CLL, and promoter DNA hypomethylation was restricted to well-defined regions. Individual hyper- and hypomethylated promoters allowed discrimination of CLL samples from healthy controls. Promoter DNA methylation patterns were confirmed in an independent patient cohort, with 11 miRNAs consistently showing an inverse correlation between DNA methylation status and expression level. Together, our findings characterize the role of epigenetic changes in the regulation of miRNA transcription and create a repository of disease-specific promoter regions that may provide additional insights into the pathogenesis of CLL. Cancer Res; 72(15); 3775–85. ©2012 AACR.</jats:p