1,817 research outputs found
Snapshot of macroalgae and fish assemblages in temperate reefs in the Southern European Atlantic Ecoregion
Most of the biodiversity studies in the South European Atlantic Shelf ecoregion are limited to shallow subtidal or intertidal habitats, while deeper reef habitats, also of relevant ecological importance, are particularly understudied. Macroalgal communities, associated fauna, and sea surface temperature were studied in deep reefs (25-30 m) at two locations in this ecoregion: Parcel, North of Portugal (41 degrees N), and Tarifa, Southern Spain (35 degrees N). Specifically, algal assemblages were assessed using biomass collection and associated ichthyofauna was assessed using visual census techniques using scuba. Seawater surface temperature was higher (>3 degrees C) in the southern region-Tarifa, compared to the northern region-Parcel. Our survey revealed 18 fish species and 23 algae species. The highest abundance of cold-water species (both macroalgae and fish species) was recorded in Parcel and warm-water species were dominant in Tarifa. In light of climate global trends, both regions might experience biodiversity shifts towards tropicalization. Current knowledge on their biodiversity is imperative to further evaluate potential shifts.info:eu-repo/semantics/publishedVersio
Translocating the blood-brain barrier using electrostatics
Copyright © 2012 Ribeiro,Domingues,
Freire,Santos and Castanho. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.Mammalian cell membranes regulate homeostasis, protein activity, and cell signaling. The charge at the membrane surface has been correlated with these key events. Although mammalian cells are known to be slightly anionic, quantitative information on the membrane charge and the importance of electrostatic interactions in pharmacokinetics and pharmacodynamics remain elusive. Recently, we reported for the first time that brain endothelial cells (EC) are more negatively charged than human umbilical cord cells, using zeta-potential measurements by dynamic light scattering. Here, we hypothesize that anionicity is a key feature of the blood-brain barrier (BBB) and contributes to select which compounds cross into the brain. For the sake of comparison, we also studied the membrane surface charge of blood components—red blood cells (RBC), platelets, and peripheral blood mononuclear cells (PBMC).To further quantitatively correlate the negative zeta-potential values with membrane charge density, model membranes with different percentages of anionic lipids were also evaluated. From all the cells tested, brain cell membranes are the most anionic and those having their lipids mostly exposed, which explains why lipophilic cationic compounds are more prone to cross the blood-brain barrier.Fundação para a Ciência e Tecnologia — Ministério da Educação e Ciência (FCT-MEC, Portugal) is acknowledged for funding (including fellowships SFRH/BD/42158/2007 to Marta M.B. Ribeiro, SFRH/BD/41750/2007 to Marco M. Domingues and SFRH/BD/70423/2010 to João M. Freire) and project PTDC/QUI-BIQ/119509/2010. Marie Curie Industry-Academia Partnerships and Pathways (European Commission) is also acknowledged for funding (FP7-PEOPLE-2007-3-1-IAPP, Project 230654)
Magnetic Properties of the Metamagnet Ising Model in a three-dimensional Lattice in a Random and Uniform Field
By employing the Monte Carlo technique we study the behavior of Metamagnet
Ising Model in a random field. The phase diagram is obtained by using the
algorithm of Glaubr in a cubic lattice of linear size with values ranging
from 16 to 42 and with periodic boundary conditions.Comment: 4 pages, 6 figure
Electronic doping of graphene by deposited transition metal atoms
We perform a phenomenological analysis of the problem of the electronic
doping of a graphene sheet by deposited transition metal atoms, which aggregate
in clusters. The sample is placed in a capacitor device such that the
electronic doping of graphene can be varied by the application of a gate
voltage and such that transport measurements can be performed via the
application of a (much smaller) voltage along the graphene sample, as reported
in the work of Pi et al. [Phys. Rev. B 80, 075406 (2009)]. The analysis allows
us to explain the thermodynamic properties of the device, such as the level of
doping of graphene and the ionisation potential of the metal clusters in terms
of the chemical interaction between graphene and the clusters. We are also
able, by modelling the metallic clusters as perfect conducting spheres, to
determine the scattering potential due to these clusters on the electronic
carriers of graphene and hence the contribution of these clusters to the
resistivity of the sample. The model presented is able to explain the
measurements performed by Pi et al. on Pt-covered graphene samples at the
lowest metallic coverages measured and we also present a theoretical argument
based on the above model that explains why significant deviations from such a
theory are observed at higher levels of coverage.Comment: 16 pages, 10 figure
Mass-degenerate Higgs bosons at 125 GeV in the Two-Higgs-Doublet Model
The analysis of the Higgs boson data by the ATLAS and CMS Collaborations
appears to exhibit an excess of h --> gamma\gamma events above the Standard
Model (SM) expectations; whereas no significant excess is observed in h --> ZZ*
--> {four lepton} events, albeit with large statistical uncertainty due to the
small data sample. These results (assuming they persist with further data)
could be explained by a pair of nearly mass-degenerate scalars, one of which is
a SM-like Higgs boson and the other is a scalar with suppressed couplings to
W+W- and ZZ. In the two Higgs doublet model, the observed \gamma\gamma and ZZ*
--> {four lepton} data can be reproduced by an approximately degenerate CP-even
(h) and CP-odd (A) Higgs boson for values of \sin(\beta-\alpha) near unity and
0.7 < \tan\beta < 1. An enhanced \gamma\gamma signal can also arise in cases
where m_h ~ m_H, m_H ~ m_A, or m_h ~ m_H ~ m_A. Since the ZZ* --> {four lepton}
signal derives primarily from a SM-like Higgs boson whereas the \gamma\gamma
signal receives contributions from two (or more) nearly mass-degenerate states,
one would expect a slightly different invariant mass peak in the ZZ* --> {four
lepton} and \gamma\gamma channels. The phenomenological consequences of such
models can be tested with additional Higgs data that will be collected at the
LHC in the near future.Comment: 18 pages, 19 pdf figures, v2: references added, v3&v4: added refs and
explanation
Thermal environment as a management tool in high-rise building
The construction industry is a growing sector in countries that are prosperous in economic development, leading to the new studies that drive this sector. Thus, it appears that the buildings have a great relationship with thermal environment, due to their constant exposure to those factors. This can influence the productivity of workers, compromising the execution of construction. This paper aims at investigating the influence of the thermal environment in building at elevated heights, establishing a relationship with productivity. For that, was done a systematic bibliographic research in more than 30 electronic sites of scientific papers with international scope, seeking to establish the stat of the art starting from the papers published in the last ten years. The definition of portals to search was based on the list included in the Metalib for Exlibris. It appears that there is a relationship between the subjects studied, although most of the survey does not include all the issues, which shows that future works to be performed in this area tend to bring great contribution in the academic community
Open Cluster Characterization via Cross-Correlation with Spectral Library
We present a characterization method based on spectral cross-correlation to
obtain the physical parameters of the controversial stellar aggregate
ESO442-SC04. The data used was obtained with GMOS at Gemini-South telescope
including 17 stars in the central region of the ob ject and 6 standard-stars.
FXCOR was used in an iterative process to obtain self-consistent radial
velocities for the standard-stars and averaged radial velocities for the
science spectra. Spectral types, effective temperature, suface gravity and
metallicities parameters were determined using FXCOR to correlate cluster
spectra with ELODIE spectral library and selecting the best correlation matches
using the Tonry and Davis Ratio (TDR). Analysis of the results suggests that
the stars in ESO442-SC04 are not bound and therefore they do not constitute a
physical system.Comment: 4-page paper from IAU symposium 266. Contains 3 eps figures and IAU
document class file 'iau.cls
A Review of Orbital Friction Stir Welding
Funding Information: The authors acknowledge the Portuguese Agência Nacional de Inovação (ANI), trough the project SI I&DT (PROJETOS MOBILIZADORES), Nº 024534-“INFANTE-Microssatélite para Vigilância Marítima, Observação da Terra e IoT no contexto de constelações”, co-financed by PORTUGAL2020, through Fundo Europeu de Desenvolvimento Regional (FEDER). Authors acknowledge the Portuguese Fundação para a Ciência e a Tecnologia (FCT–MCTES) for its financial support via the project UID/EMS/00667/2019 (UNIDEMI). Authors acknowledge funding by national funds from FCT-Fundação para a Ciência e a Tecnologia, I.P., in the scope of the projects LA/P/0037/2020, UIDP/50025/2020 and UIDB/50025/2020 of the Associate Laboratory Institute of Nanostructures, Nanomodelling and Nanofabrication–i3N. Publisher Copyright: © 2023 by the authors.Friction stir welding is a solid-state joining process widely used in several industrial applications. One of its variants, orbital friction stir welding, is of key importance in fundamental industries such as oil and gas and aerospace. For orbital friction stir welding, there is a need to develop not only new process parameters but also tools and ancillary mechanisms that can ensure sound, high-performing joints are obtained. This review assesses the current state of orbital friction stir welding, highlighting several key aspects related to this technology.publishersversionpublishe
Evaluation of the cytotoxicity (HepG2) and chemical composition of polar extracts from the ruderal species Coleostephus myconis (L.) Rchb.f.
Coleostephus myconis (L.) Rchb.f. (Asteraceae) is a highly disseminated plant species with ruderal and persistent growth. Owing to its advantageous agronomic properties, C. myconis might have industrial applications. However, this species needs to be comprehensively characterized before any potential use. In a previous study, the phenolic composition and antioxidant activity of different C. myconis tissues were characterized. This investigation was extended to examine the cytotoxic potential of selected plant tissues (flowers and green parts) using a HepG2 cell line by utilizing the lysosomal neutral red uptake assay or mitochondrial (3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide assay. In addition, the macronutrients content, lipophilic compounds (fatty acids, tocopherols), and amino acids were also determined. C. myconis flowers were used in the senescence stage, which was previously identified as the stage that presented maximal phenolic content and highest antioxidant activity. In contrast, stems and leaves were employed due to their high biomass proportion. Regarding cytotoxicity, mitochondrial and lysosomal damage was only significant when HepG2 cells were exposed to the highest extract concentrations (stems and leaves, 0.9 mg/ml; senescent flowers, 0.3 mg/ml). Chemically, the senescent flowers were mostly characterized by their high levels of fat, amino acids (especially threonine), oleic acid, ß-, and ?-tocopherol, while stems and leaves contained high concentrations of carbohydrates, linolenic acid, and a-tocopherol. In general, these results provide information regarding the threshold concentrations of C. myconis extracts that might be used in different applications without toxicity hazards.The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support to REQUIMTE (PEst-C/EQB/LA0006/2014) and to CIMO (UID/AGR/00690/2013). J.C.M. Barreira, Carla Costa, and Filipa B. Pimentel thank FCT, POPH-QREN, and FSE for their grants (SFRH/BPD/72802/2010, SFRH/BPD/96196/2013 and SFRH/BD/109042/2015, respectively).info:eu-repo/semantics/publishedVersio
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