217 research outputs found
Generalized parton distributions and Deeply Virtual Compton Scattering in Color Glass Condensate model
Within the framework of the Color Glass Condensate model, we evaluate quark
and gluon Generalized Parton Distributions (GPDs) and the cross section of
Deeply Virtual Compton Scattering (DVCS) in the small- region. We
demonstrate that the DVCS cross section becomes independent of energy in the
limit of very small , which clearly indicates saturation of the DVCS
cross section. Our predictions for the GPDs and the DVCS cross section at
high-energies can be tested at the future Electron-Ion Collider and in
ultra-peripheral nucleus-nucleus collisions at the LHC.Comment: 20 pages, 8 Figure
Exact quantum states of a general time-dependent quadratic system from classical action
A generalization of driven harmonic oscillator with time-dependent mass and
frequency, by adding total time-derivative terms to the Lagrangian, is
considered. The generalization which gives a general quadratic Hamiltonian
system does not change the classical equation of motion. Based on the
observation by Feynman and Hibbs, the propagators (kernels) of the systems are
calculated from the classical action, in terms of solutions of the classical
equation of motion: two homogeneous and one particular solutions. The kernels
are then used to find wave functions which satisfy the Schr\"{o}dinger
equation. One of the wave functions is shown to be that of a Gaussian pure
state. In every case considered, we prove that the kernel does not depend on
the way of choosing the classical solutions, while the wave functions depend on
the choice. The generalization which gives a rather complicated quadratic
Hamiltonian is simply interpreted as acting an unitary transformation to the
driven harmonic oscillator system in the Hamiltonian formulation.Comment: Submitted to Phys. Rev.
Sum rules and dualities for generalized parton distributions: is there a holographic principle?
To leading order approximation, the physical content of generalized parton
distributions (GPDs) that is accessible in deep virtual electroproduction of
photons or mesons is contained in their value on the cross-over trajectory.
This trajectory separates the t-channel and s-channel dominated GPD regions.
The underlying Lorentz covariance implies correspondence between these two
regions through their relation to GPDs on the cross-over trajectory. This point
of view leads to a family of GPD sum rules which are a quark analogue of finite
energy sum rules and it guides us to a new phenomenological GPD concept. As an
example, we discuss the constraints from the JLab/Hall A data on the dominant
u-quark GPD H. The question arises whether GPDs are governed by some kind of
holographic principle.Comment: 45 pages, 4 figures, Sect. 2 reorganized for clarity. Typos in Eq.
(20) corrected. 4 new refs. Matches published versio
The transition form factors for semi-leptonic weak decays of in QCD sum rules
Within the Standard Model, we investigate the semi-leptonic weak decays of
. The various form factors of transiting to a single charmed
meson () are studied in the framework of the QCD sum rules.
These form factors fully determine the rates of the weak semi-leptonic decays
of and provide valuable information about the non-perturbative QCD
effects. Our results indicate that the decay rate of the semi-leptonic weak
decay mode is at order of .Comment: 28 pages, 6 figures, revised version to be published in Eur.Phys.J.
Magnetic Field Amplification in Galaxy Clusters and its Simulation
We review the present theoretical and numerical understanding of magnetic
field amplification in cosmic large-scale structure, on length scales of galaxy
clusters and beyond. Structure formation drives compression and turbulence,
which amplify tiny magnetic seed fields to the microGauss values that are
observed in the intracluster medium. This process is intimately connected to
the properties of turbulence and the microphysics of the intra-cluster medium.
Additional roles are played by merger induced shocks that sweep through the
intra-cluster medium and motions induced by sloshing cool cores. The accurate
simulation of magnetic field amplification in clusters still poses a serious
challenge for simulations of cosmological structure formation. We review the
current literature on cosmological simulations that include magnetic fields and
outline theoretical as well as numerical challenges.Comment: 60 pages, 19 Figure
Carbon-cryogel hierarchical composites as effective and scalable filters for removal of trace organic pollutants from water
Effective technologies are required to remove organic micropollutants from large fluid volumes to overcome present and future challenges in water and effluent treatment. A novel hierarchical composite filter material for rapid and effective removal of polar organic contaminants from water was developed. The composite is fabricated from phenolic resin-derived carbon microbeads with controllable porous structure and specific surface area embedded in a monolithic, flow permeable, poly(vinyl alcohol) cryogel. The bead-embedded monolithic composite filter retains the bulk of the high adsorptive capacity of the carbon microbeads while improving pore diffusion rates of organic pollutants. Water spiked with organic contaminants, both at environmentally relevant concentrations and at high levels of contamination, was used to determine the purification limits of the filter. Flow through tests using water spiked with the pesticides atrazine (32 mg/L) and malathion (16 mg/L) indicated maximum adsorptive capacities of 641 and 591 mg pollutant/g carbon, respectively. Over 400 bed volumes of water contaminated with 32 mg atrazine/L, and over 27,400 bed volumes of water contaminated with 2 μg atrazine/L, were treated before pesticide guideline values of 0.1 μg/L were exceeded. High adsorptive capacity was maintained when using water with high total organic carbon (TOC) levels and high salinity. The toxicity of water filtrates was tested in vitro with human epithelial cells with no evidence of cytotoxicity after initial washing
Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
An increasing number of breast cancer patients develop brain metastases (BM). Standard-of-care treatments are largely inefficient, and breast cancer brain metastasis (BCBM) patients are considered untreatable. Immunotherapies are not successfully employed in BCBM, in part because breast cancer is a “cold” tumor and also because the brain tissue has a unique immune landscape. Here, we generate and characterize immunocompetent models of BCBM derived from PyMT and Neu mammary tumors to test how harnessing the pro-senescence properties of doxorubicin can be used to prime the specific immune BCBM microenvironment. We reveal that BCBM senescent cells, induced by doxorubicin, trigger the recruitment of PD1-expressing T cells to the brain. Importantly, we demonstrate that induction of senescence with doxorubicin improves the efficacy of immunotherapy with anti-PD1 in BCBM in a CD8 T cell-dependent manner, thereby providing an optimized strategy to introduce immune-based treatments in this lethal disease. In addition, our BCBM models can be used for pre-clinical testing of other therapeutic strategies in the future
Projected WIMP sensitivity of the LUX-ZEPLIN dark matter experiment
LUX-ZEPLIN (LZ) is a next-generation dark matter direct detection experiment that will operate 4850 feet underground at the Sanford Underground Research Facility (SURF) in Lead, South Dakota, USA. Using a two-phase xenon detector with an active mass of 7 tonnes, LZ will search primarily for low-energy interactions with weakly interacting massive particles (WIMPs), which are hypothesized to make up the dark matter in our galactic halo. In this paper, the projected WIMP sensitivity of LZ is presented based on the latest background estimates and simulations of the detector. For a 1000 live day run using a 5.6-tonne fiducial mass, LZ is projected to exclude at 90% confidence level spin-independent WIMP-nucleon cross sections above 1.4 × 10-48cm2 for a 40 GeV/c2 mass WIMP.
Additionally, a 5σ discovery potential is projected, reaching cross sections below the exclusion limits of recent experiments. For spin-dependent WIMP-neutron(-proton) scattering, a sensitivity of 2.3 × 10−43 cm2 (7.1 × 10−42 cm2) for a 40 GeV/c2
mass WIMP is expected. With underground installation well underway, LZ is on track for commissioning at SURF in 2020
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