Structured System and Software Design of Distributed Control Computer of Mechatronic Facility for Space Research

The structured system and software designmethod of the distributed control computer network of themechatronic scientific facility for automatic hightemperature material processing in the space in microgravitationenvironment is presented in the paper. Thefacility distributed computer controls special extra lowspeed vibrationless electric drives, multi-zone hightemperature furnace heating system and severalmeasurement devices. The computer is equipped withspecial technological language to be possible to specifyexperiment time flow. Computer network nodes have manyuser processes (threads) so efficient, reliable, selfdocumented, and low overhead scheduler dispatcher isrequired. The table driven coroutines have been designed

Psychotherapeutic care for adolescents failing in difficult situations.

Ústředním motivem disertační práce bylo nalezení efektivního způsobu, jak pomoci mladým lidem na hranici dospělosti prostřednictvím psychoterapeutické péče k zvládnutí náročných situacích, v nichž se jim nepodařilo obstát. Jejich selhávání se projevilo nejčastěji nedostatečnými výsledky při plnění školních povinností ve škole nebo pracovních úkolů na pracovištích odborného výcviku. Ačkoli příčiny byly různé, výsledek u všech stejně vyústil návrhem na vyloučení ze střední školy nebo odborného učiliště. Účelným se jevilo, a to jak v teoretických východiscích, tak ve výzkumu a jeho aplikacích, poukázat na velké množství vlivů a jejich kombinací, které vstupují do života každého jedince a jak je proto velice složité, ba přímo nemožné přesně identifikovat příčiny vzniku krize dospívajícího adolescenta. Všem zúčastněným zkoumaným osobám se však nastavilo zrcadlo jejich vlastních výpovědí prostřednictvím výsledků psychodiagnostických testů, artefaktů a rozhovorů s jejich rodiči, učiteli, mistry, ale především nimi samými. A spolu s nimi jsme hledali cestu z jejich krizové situace.Teoretická východiska vysvětlují klíčové pojmy a jejich souvislosti přímo k psychologickému výzkumu a jeho aplikování do terapeutické péče. Popisují psychologickou charakteristiku adolescence, v níž se snaží postihnout význam tělesných...The central motive of this dissertation thesis was to find an effective method of helping young people approaching adulthood manage difficult situations - which they were unable to deal with - through psychotherapeutic care. Their failure was most often demonstrated by their unsatisfactory results in school performance or duties given at training workplaces. Although the causes were different, the outcome was the same for all of them: a proposal to suspend them from their secondary school or their training college. In theoretical solutions as well as in research and its applications it seemed useful to refer to many influences and their combinations that enter the life of each individual. Therefore it is very difficult, even impossible to exactly identify the causes of a beginning of a crisis of a maturing adolescent. All involved examined persons were nevertheless faced with a mirror of their own testimonies through the results of psycho-diagnostical tests, artefacts and discussions with their parents, teachers, vocational trainers and especially with themselves. And together with them, we were searching for a way out from their crisis. The theoretical solutions explain the key concepts and their relations directly to psychological research and its application into the therapeutic care. They describe a...Department of PsychologyKatedra psychologieFilozofická fakultaFaculty of Art

Genomic and conventional breeding values for clinical mastitis

Conventional and genomic breeding values for clinical mastitis were estimated,based on a dataset of 15,905 cows (36,250 lactations) from 10 farms, calving years from 1996 to 2014. The number of genotyped bulls was 2647 and 799 of them had offspring among the surveyed cows. Pedigree consisted of 64,306 individuals. Analyzed trait was defined as the number of incidence of clinical mastitis per standard lactation. Parity was limited from 1 to 7. The highest proportion of mastitis disease was observed in early lactation and decreased with month of lactation, while there was an upswing of diseases with parity. Genetic trend for cows showed a deteriorating tendency for clinical mastitis. From 1992 to 2010 there was a rise in the relative values of breeding values from 88% to 112% (worsening). Relative breeding values of these bulls were on average above 100%. The correlations between classical genomic breeding values and the values were high: 93% for the whole sample, 81% to 48 young genomic bulls without daughters born in years 2011 and 2012

Preliminary analysis of utilization of genomic relationship in mating plan of Old Kladruber horse

The study analyzed 48 Old Kladruber horses genotyped by Illumina Equine SNP70 BeadChip for usefulness of genomic data in determining of mating plan. Totally 12 variants of data filtering and their impact on calculations in dependence of different parameters of GenCall Score, Minor Allele Frequency and assumed average values of loci of ancestors (l) was investigated. For possibility of comparison between genomic and commonly evaluated relationships, pedigree based relationship matrix was constructed and subsequently subtraction of pedigree from genomic matrix was performed. All matrices were thoroughly inspected and most suitable setting of parameters was chosen. Evaluation of genomic relationships can be successfully implemented in more precise method of mating plan design of Old Kladruber horses. Further genotyping and development of method for rescaling of differences between genomic and pedigree relationship matrices´ elements is advised for a purpose of better interpretation of results by breeders

GWAS in practical cattle breeding in Czech Republic, single step method, genetic progress

Development of genetic evaluation of animals is permanent process. It was going from estimated breeding value (EBV) calculated by CC-test, across a BLUP – animal model and RR-TDM, to the genomic enhanced breeding value (GEBV) using genetic markers. Methods of genetic evaluation become a part of marketing strategies of insemination companies. Therefore all countries and association of breeders seek to be compatible with others. Now we are in a period of massive global implementation of genomic evaluation, which combines traditional BLUP with huge quantity of genetic SNP markers. Multi-step procedures are now usual in practice, which work with deregressed proofs. Development of methods attained to the single-step procedure (ssGBLUP) which overcomes some difficulties of previous methods, improves reliabilities of evaluation and compares all animals, genotyped and ungenotyped, in entire nation-wide population. Genomic evaluation influence above all young genotyped animals. In Czech Republic single-step procedure is routinely used for national evaluation of milk, linear type traits, reproduction and longevity. GEBVs are accompanied by genomic reliabilities. Genetic trends over last 20 years are in some traits different for genomic evaluation compared to traditional BLUP evaluation, although input data and genetic parameters (heritability) are the same and genotyped animals were only small proportion from entire evaluated population. Differences in genetic trends increase mainly in new batches of animals. Reason of it could be in the changed variability of breeding values and “genomic correction” of relationship between animals, which is expanded from genotyped animals to others individuals in a population. Keywords: genomic breeding value, single-step, genomic relationship, genetic trend, SNP ReferencesBauer, J. et al. (2014) Approximation of the reliability of single-step genomic breeding values for dairy cattle in the Czech Republic. Anim. Sci. Papers and Reports, 32, pp. 301-306.Bauer, J., Přibyl, J. and Vostrý, L. (2015) Contribution of domestic production records and Interbull EBV on approximate reliabilities of single-step genomic breeding values in dairy cattle. Czech J. Anim. Sci., 60, 263-267.Candrák, J., Kadlečík O. and Schaeffer L.R. (1997) The use of test-day model for Slovak cattle populations. In: Proc. 48th Annual Meeting of the European Association for Animal Production, Vienna, Austria, August 25–28.Christensen,  O.F. and Lund, M.S. (2010) Genomic prediction when some animals are not genotyped. Genet.Sel.Evol. 42, pp. 2.Fisher, R.A. (1918) The correlation between relatives in the supposition of Mendelianinheritance. Trans. Roy. Soc. Edinb. 52, pp. 399-433.            Fragomeni, B.O. et al. (2015) Hot topic: Use of genomic recursions in single-step genomic best linear unbiased predictor (BLUP) with a large number of genotypes. J. Dairy Sci., 98, pp. 4090-4094.Gao, H. et al. (2012) Comparison on genomic predictions using three GBLUP methods and two single step blending methods in the Nordic Holstein population. Genet. Sel.Evol. 44, pp. 8.Legarra A., Aguilar I. and Misztal, I. (2009) A relationship matrix including full pedigree and genomic information. J. Dairy Sci., 92, pp. 4656-4663.Masuda, Y. et al. (2016) Implementation of genomic recursions in single-step genomic best linear unbiased predictor for US Holsteins with a large number of genotyped animals. J. Dairy Sci., 99, pp. 1968-1974.Mendel, G.J. (1866) Versuche über Pflanzen-Hybriden. Verh. Naturforsch. Ver. Brünn 4, pp. 3–47 (1901, J. R. Hortic. Soc. 26, pp. 1–32).Meuwissen, T.H.E., Hayes, B.J. and Goddard, M.E. (2001) Prediction of total genetic value using genome-wide dense marker maps. Genetics, 157, pp. 1819–1829.Misztal, I., Legarra A. and Aguilar, I. (2009) Computing procedures for genetic evaluation including phenotypic, full pedigree, and genomic information. J. Dairy Sci., 92, pp. 4648–4655.Misztal, I. et al. (2013) Methods to approximate reliabilities in single-step genomic evaluation. J. Dairy Sci., 96, pp. 647-654.Pešek, P., Přibyl, J. and Vostrý, L. (2015) Genetic variances of SNP loci for milk yield in dairy cattle. J. Appl. Genet., 56, pp. 339-347.Přibyl, J. et al. (2014) Domestic and Interbull information in the single step genomic evaluation of Holstein milk production.  Czech J. Anim. Sci., 59, pp. 409-415.Přibyl, J. et al. (2015) Domestic estimated breeding values and genomic enhanced breeding values of bulls in comparison with their foreign genomic enhanced breeding values. Animal, 9, pp. 1635-1642.VanRaden, P.M. (2008) Efficient methods to compute genomic predictions. J. Dairy Sci., 91, pp. 4414–4423.VanRaden, P.M. et al. (2011) Genomic evaluations with many more genotypes. Genet. Sel.Evol. 43, pp. 10.Wright, S. (1921) Systems of mating. Genetics. 6, pp. 111-178.Zavadilová, L. et al. (2014) Single-step genomic evaluation for linear type traits of Holstein cows in Czech Republic. Anim. Sci. Papers and Reports vol. 32, pp. 201-208.

RTX proteins: a highly diverse family secreted by a common mechanism

Repeats-in-toxin (RTX) exoproteins of Gram-negative bacteria form a steadily growing family of proteins with diverse biological functions. Their common feature is the unique mode of export across the bacterial envelope via the type I secretion system and the characteristic, typically nonapeptide, glycine- and aspartate-rich repeats binding Ca2+ ions. In this review, we summarize the current state of knowledge on the organization of rtx loci and on the biological and biochemical activities of therein encoded proteins. Applying several types of bioinformatic screens on the steadily growing set of sequenced bacterial genomes, over 1000 RTX family members were detected, with the biological functions of most of them remaining to be characterized. Activities of the so far characterized RTX family members are then discussed and classified according to functional categories, ranging from the historically first characterized pore-forming RTX leukotoxins, through the large multifunctional enzymatic toxins, bacteriocins, nodulation proteins, surface layer proteins, up to secreted hydrolytic enzymes exhibiting metalloprotease or lipase activities of industrial interest

A comparison of psychiatric day hospitals in five European countries - Implications of their diversity for day hospital research

REJECTED - publisher's policy states that PDF cannot be archive

EPMA-World Congress 2015: Bonn, Germany. 3-5 September 2015

Table of contents A1 Predictive and prognostic biomarker panel for targeted application of radioembolisation improving individual outcomes in hepatocellular carcinoma Jella-Andrea Abraham, Olga Golubnitschaja A2 Integrated market access approach amplifying value of “Rx-CDx” Ildar Akhmetov A3 Disaster response: an opportunity to improve global healthcare Russell J. Andrews, Leonidas Quintana A4 USA PPPM: proscriptive, profligate, profiteering medicine-good for 1 % wealthy, not for 99 % unhealthy Russell J. Andrews A5 The role of IDO in a murine model of gingivitis: predictive and therapeutic potentials Babak Baban, Jun Yao Liu, Xu Qin, Tailing Wang, Mahmood S. Mozaffari A6 Specific diets for personalised treatment of diabetes type 2 Viktoriia V. Bati, Tamara V. Meleshko, Olga B. Levchuk, Nadiya V. Boyko A7 Towards personalized physiotherapeutic approach Joanna Bauer, Ewa Boerner, Halina Podbielska A8 Cells, animal, SHIME and in silico models for detection and verification of specific biomarkers of non-communicable chronic diseases Alojz Bomba, Viktor O. Petrov, Volodymyr G. Drobnych, Rostyslav V. Bubnov, Oksana M. Bykova, Nadiya V. Boyko A9 INTERACT-chronic care model: Self-treatment by patients with decision support e-Health solution Hans-Peter Brunner-La Rocca, Lutz Fleischhacker, Olga Golubnitschaja, Frank Heemskerk, Thomas Helms, Tiny Jaarsma, Judita Kinkorova, Jan Ramaekers, Peter Ruff, Ivana Schnur, Emilio Vanoli, Jose Verdu A10 PPPM in cardiovascular medicine in 2015 Hans-Peter Brunner-La Rocca A11 Magnetic resonance imaging of nanoparticles in mice, potential for theranostic and contrast media development – pilot results Rostyslav V. Bubnov, Sergiy A. Grabovetskyi, Olena M. Mykhalchenko, Natalia O. Tymoshok, Oleksandr B. Shcherbakov, Igor P. Semeniv, Mykola Y. Spivak A12 Ultrasound diagnosis for diabetic neuropathy - comparative study Rostyslav V. Bubnov, Tetyana V. Ostapenko A13 Ultrasound for stratification patients with diabetic foot ulcers for prevention and personalized treatment - pilot results Rostyslav V. Bubnov, Nazarii M. Kobyliak, Nadiya M. Zholobak, Mykola Ya. Spivak A14 Project ImaGenX – designing and executing a questionnaire on environment and lifestyle risk of breast cancer John Paul Cauchi A15 Genomics – a new structural brand of predictive, preventive and personalized medicine or the new driver as well? Dmitrii Cherepakhin, Marina Bakay, Artem Borovikov, Sergey Suchkov A16 Survey of questionnaires for evaluation of the quality of life in various medical fields Barbara Cieślik, Agnieszka Migasiewicz, Maria-Luiza Podbielska, Markus Pelleter, Agnieszka Giemza, Halina Podbielska A17 Personalized molecular treatment for muscular dystrophies Sebahattin Cirak A18 Secondary mutations in circulating tumour DNA for acquired drug resistance in patients with advanced ALK + NSCLC Marzia Del Re, Paola Bordi, Valentina Citi, Marta Palombi, Carmine Pinto, Marcello Tiseo, Romano Danesi A19 Recombinant species-specific FcεRI alpha proteins for diagnosis of IgE-mediated allergies in dogs, cats and horses Lukas Einhorn, Judit Fazekas, Martina Muhr, Alexandra Schoos, Lucia Panakova, Ina Herrmann, Krisztina Manzano-Szalai, Kumiko Oida, Edda Fiebiger, Josef Singer, Erika Jensen-Jarolim A20 Global methodology for developmental neurotoxicity testing in humans and animals early and chronically exposed to chemical contaminants Arpiné A. Elnar, Nadia Ouamara, Nadiya Boyko, Xavier Coumoul, Jean-Philippe Antignac, Bruno Le Bizec, Gauthier Eppe, Jenny Renaut, Torsten Bonn, Cédric Guignard, Margherita Ferrante, Maria Liusa Chiusano, Salvatore Cuzzocrea, Gerard O'Keeffe, John Cryan, Michelle Bisson, Amina Barakat, Ihsane Hmamouchi, Nasser Zawia, Anumantha Kanthasamy, Glen E. Kisby, Rui Alves, Oscar Villacañas Pérez, Kim Burgard, Peter Spencer, Norbert Bomba, Martin Haranta, Nina Zaitseva, Irina May, Stéphanie Grojean, Mathilde Body-Malapel, Florencia Harari, Raul Harari, Kristina Yeghiazaryan, Olga Golubnitschaja, Vittorio Calabrese, Christophe Nemos, Rachid Soulimani A21 Mental indicators at young people with attributes hypertension and pre-hypertension Maria E. Evsevyeva, Elena A. Mishenko, Zurida V. Kumukova, Evgeniy V. Chudnovsky, Tatyana A. Smirnova A22 On the approaches to the early diagnosis of stress-induced hypertension in young employees of State law enforcement agencies Maria E. Evsevyeva, Ludmila V. Ivanova, Michail V. Eremin, Maria V. Rostovtseva A23 Сentral aortic pressure and indexes of augmentation in young persons in view of risk factors Maria E. Evsevyeva, Michail V. Eremin, Vladimir I. Koshel, Oksana V. Sergeeva, Nadesgda M. Konovalova A24 Breast cancer prediction and prevention: Are reliable biomarkers in horizon? Shantanu Girotra, Olga Golubnitschaja A25 Flammer Syndrome and potential formation of pre-metastatic niches: A multi-centred study on phenotyping, patient stratification, prediction and potential prevention of aggressive breast cancer and metastatic disease Olga Golubnitschaja, Manuel Debald, Walther Kuhn, Kristina Yeghiazaryan, Rostyslav V. Bubnov, Vadym M. Goncharenko, Ulyana Lushchyk, Godfrey Grech, Katarzyna Konieczka A26 Innovative tools for prenatal diagnostics and monitoring: improving individual pregnancy outcomes and health-economy in EU Olga Golubnitschaja, Jan Jaap Erwich, Vincenzo Costigliola, Kristina Yeghiazaryan, Ulrich Gembruch A27 Immunohistochemical assessment of APUD cells in endometriosis Vadym M. Goncharenko, Vasyl O. Beniuk, Olga V. Kalenska, Rostyslav V. Bubnov A28 Updating personalized management algorithm of endometrial hyperplasia in pre-menopause women Vadym M. Goncharenko, Vasyl O. Beniuk, Rostyslav V. Bubnov, Olga Melnychuk A29 The personified treatment approach of polimorbid patients with periodontal inflammatory diseases Irina A. Gorbacheva, Lyudmila Y. Orekhova, Vadim V. Tachalov A30 Ukrainian experience in hybrid war – the challenge to update algorithms for personalized care and early prevention of different military injuries Olena I. Grechanyk, Rizvan Ya. Abdullaiev, Rostyslav V. Bubnov A31 Tear fluid biomarkers: a comparison of tear fluid sampling and storage protocols Suzanne Hagan, Eilidh Martin, Ian Pearce, Katherine Oliver A32 The correlation of dietary habits with gingival problems during menstruation Cenk Haytac, Fariz Salimov, Servin Yoksul, Anatoly A. Kunin, Natalia S. Moiseeva A33 Genomic medicine in a contemporary Spanish population of prostate cancer: our experience Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara, Antonia Angulo, Francisco Javier Machuca Santa-Cruz A34 Challenges, opportunities and collaborations for personalized medicine applicability in uro-oncological disease Bernardo Herrera-Imbroda, Sergio del Río-González, Maria Fernanda Lara A35 Metabolic hallmarks of cancer as targets for a personalized therapy John Ionescu A36 Influence of genetic polymorphism as a predictor of the development of periodontal disease in patients with gastric ulcer and 12 duodenal ulcer Alfiya Z. Isamulaeva, Anatoly A. Kunin, Shamil Sh. Magomedov, Aida I. Isamulaeva A37 Challenges in diabetic macular edema Tatjana Josifova A38 Overview of the EPMA strategies in laboratory medicine relevant for PPPM Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja, Vincenzo Costigliola A39 EPMA initiative for effective organization of medical travel: European concepts and criteria Vincenzo Costigliola, Marko Kapalla, Juraj Kubáň, Olga Golubnitschaja A40 Design and innovation in e-textiles: implications for PPPM Anthony Kent, Tom Fisher, Tilak Dias A41 Biobank in Pilsen as a member of national node BBMRI_CZ Judita Kinkorová, Ondřej Topolčan A42 Big data in personalized medicine: hype and hope Matthias Kohl A43 The 3P approach as the platform of the European Dentistry Department (DPPPD) Anatoly A. Kunin, Natalia S. Moiseeva A44 The endometrium cytokine patterns for predictive diagnosis of proliferation severity and cancer prevention Andrii I. Kurchenko, Vasyl A. Beniuk, Vadym M. Goncharenko, Rostyslav V. Bubnov, Nadiya V. Boyko, Andriy M. Strokan A45 A monocyte-based in-vitro system for testing individual responses to the implanted material: future for personalized implant construction Julia Kzhyshkowska, Alexandru Gudima, Ksenia S. Stankevich, Victor D. Filimonov4, Harald Klüter, Evgeniya M. Mamontova, Sergei I. Tverdokhlebov A46 Prediction and prevention of adverse health effects by meteorological factors: Biomarker patterns and creation of a device for self-monitoring and integrated care Ulyana B. Lushchyk, Viktor V. Novytskyy, Igor P. Babii, Nadiya G. Lushchyk, Lyudmyla S. Riabets, Ivanna I. Legka A47 Targeting "disease signatures" towards personalized healthcare Mira Marcus-Kalish, Alexis Mitelpunkt, Tal Galili, Neta Shachar, Yoav Benjamini A48 Influence of the skin imperfection on the personal quality of life and possible tools for objective diagnosis Agnieszka Migasiewicz, Markus Pelleter, Joanna Bauer, Ewelina Dereń, Halina Podbielska A49 The new direction in caries prevention based on the ultrastructure of dental hard tissues and filling materials Natalia S. Moiseeva, Anatoly A. Kunin, Dmitry A. Kunin A50 The use of LED radiation in prevention of dental diseases Natalia S. Moiseeva, Yury A. Ippolitov, Dmitry A. Kunin, Alexei N. Morozov, Natalia V. Chirkova, Nakhid T. Aliev A51 Status of endothelial progenitor cells in diabetic nephropathy: predictive and preventive potentials Mahmood S. Mozaffari, Jun Yao Liu, Babak Baban A52 The status of glucocorticoid-induced leucine zipper protein in salivary gland in Sjögren’s syndrome: predictive and personalized treatment potentials Mahmood S. Mozaffari, Jun Yao Liu, Rafik Abdelsayed, Xing-Ming Shi, Babak Baban A53 Maximal aerobic capacity - important quality marker of health Jaroslav Novák, Milan Štork, Václav Zeman A54 The EMPOWER project: laboratory medicine and Horizon 2020 Wytze P. Oosterhuis, Elvar Theodorsson A55 Personality profile manifestations in patient’s attitude to oral care and adherence to doctor’s prescriptions Lyudmila Y. Orekhova, Tatyana V. Kudryavtseva, Elena R. Isaeva, Vadim V. Tachalov, Ekaterina S. Loboda A56 Results of an European survey on personalized medicine addressed to directions of laboratory medicine Mario Pazzagli, Francesca Malentacchi, Irene Mancini, Ivan Brandslund, Pieter Vermeersch, Matthias Schwab, Janja Marc, Ron H.N. van Schaik, Gerard Siest, Elvar Theodorsson, Chiara Di Resta A57 MCI or early dementia predictive speech based diagnosis techniques Matus Pleva, Jozef Juhar A58 Personalized speech based mobile application for eHealth Matus Pleva, Jozef Juhar A59 Circulating tumor cell-free DNA as the biomarker in the management of cancer patients Jiří Polívka jr., Filip Janků, Martin Pešta, Jan Doležal, Milena Králíčková, Jiří Polívka A60 Complex stroke care – educational programme in Stroke Centre University Hospital Plzen Jiří Polívka, Alena Lukešová, Nina Müllerová, Petr Ševčík, Vladimír Rohan A61 Sleep apnea and sleep fragmentation contribute to brain aging Kneginja Richter, Lence Miloseva, Günter Niklewski A62 Personalised approach for sleep disturbances in shift workers Kneginja Richter, Jens Acker, Guenter Niklewski A63 Medical travel and innovative PPPM clusters: new concept of integration Olga Safonicheva, Vincenzo Costigliola A64 Medical travel and women health Olga Safonicheva A65 Continuity of generations in the training of specialists in the field of reconstructive microsurgery Maxim Sautin, Janna Sinelnikova, Sergey Suchkov A66 Telemonitoring of stroke patients – empirical evidence of individual risk management results from an observational study in Germany Songül Secer, Stephan von Bandemer A67 Women’s increasing breast cancer risk with n-6 fatty acid intake explained by estrogen-fatty acid interactive effect on DNA damage: implications for gender-specific nutrition within personalized medicine Niva Shapira A68 Cytobacterioscopy of the gingival crevicular fluid as a method for preventive diagnosis of periodontal diseases Aleksandr Shcherbakov, Anatoly A. Kunin, Natalia S. Moiseeva A69 Use of specially treated composites in dentistry to avoid violations of aesthetics Bogdan R. Shumilovich, Zhanna Lipkind, Yulia Vorobieva, Dmitry A. Kunin, Anastasiia V. Sudareva A70 National eHealth system – platform for preventive, predictive and personalized diabetes care Ivica Smokovski, Tatjana Milenkovic A72 The common energy levels of Prof. Szent-Györgyi, the intrinsic chemistry of melanin, and the muscle physiopathology. Implications in the context of Preventive, Predictive, and Personalized Medicine Arturo Solís-Herrera, María del Carmen Arias-Esparza, Sergey Suchkov A73 Plurality and individuality of hepatocellular carcinoma: PPPM perspectives Krishna Chander Sridhar, Olga Golubnitschaja A74 Strategic aspects of higher medical education reforms to secure newer educational platforms for getting biopharma professionals matures Maria Studneva, Sihong Song, James Creeden, Мark Мandrik, Sergey Suchkov A75 Overview of the strategies and activities of the European Federation of Clinical Chemistry and Laboratory Medicine, (EFLM) Elvar Theodorsson, EFLM A76 New spectroscopic techniques for point of care label free diagnostics Syed A. M. Tofail A77 Tumor markers for personalized medicine and oncology - the role of Laboratory Medicine Ondřej Topolčan, Judita Kinkorová, Ondřej Fiala, Marie Karlíková, Šárka Svobodová, Radek Kučera, Radka Fuchsová, Vladislav Třeška, Václav Šimánek, Ladislav Pecen, Jan Šoupal, Štěpán Svačina2 A78 Modern medical terminology (MMT) as a driver of the global educational reforms Evgeniya Tretyak, Maria Studneva, Sergey Suchkov A79 Juvenile hypertension; the relevance of novel predictive, preventive and personalized assessment of its determinants Francesca M. Trovato, G. Fabio Martines, Daniela Brischetto, Daniela Catalano, Giuseppe Musumeci, Guglielmo M. Trovato A80 Proteomarkers Biotech George Th. Tsangaris, Athanasios K. Anagnostopoulos A81 Proteomics and mass spectrometry based non-invasive prenatal testing of fetal health and pregnancy complications George Th. Tsangaris, Athanasios K. Anagnostopoulos A82 Integrated Ecosystem for an Integrated Care model for Heart Failure (HF) patients including related comorbidities (ZENITH) José Verdú, German Gutiérrez, Jordi Rovira, Marta Martinez, Lutz Fleischhacker, Donna Green, Arthur Garson, Elena Tamburini, Stefano Cuomo, Juan Martinez-Leon, Teresa Abrisqueta, Hans-Peter Brunner-La Rocca, Tiny Jaarsma, Teresa Arredondo, Cecilia Vera, Giuseppe Fico, Olga Golubnitschaja, Fernando Arribas, Martina Onderco, Isabel Vara, on behalf of ZENITH consortium A83 Predictive, preventive and personalized medicine in diabetes onset and complication (MOSAIC project) José Verdú, Francesco Sambo, Barbara Di Camillo, Claudio Cobelli, Andrea Facchinetti, Giuseppe Fico, Riccardo Bellazzi, Lucia Sacchi, Arianna Dagliati, Daniele Segnani, Valentina Tibollo, Manuel Ottaviano, Rafael Gabriel, Leif Groop, Jacqueline Postma, Antonio Martinez, Liisa Hakaste, Tiinamaija Tuomi, Konstantia Zarkogianni, on behalf of MOSAIC consortium A84 Possibilities for personalized therapy of diabetes using in vitro screening of insulin and oral hypoglycemic agents Igor Volchek, Nina Pototskaya, Andrey Petrov A85 The innovative technology for personalized therapy of human diseases based on in vitro drug screening Igor Volchek, Nadezhda Pototskaya, Andrey Petrov A86 Bone destruction and temporomandibular joint: predictive markers, pathogenetic aspects and quality of life Ülle Voog-Oras, Oksana Jagur, Edvitar Leibur, Priit Niibo, Triin Jagomägi, Minh Son Nguyen, Chris Pruunsild, Dagmar Piikov, Mare Saag A87 Sub-optimal health management – global vision for concepts in medical travel Wei Wang A88 Sub-optimal health management: synergic PPPM-TCAM approach Wei Wang A89 Innovative technologies for minimal invasive diagnostics Andreas Weinhäusel, Walter Pulverer, Matthias Wielscher, Manuela Hofner, Christa Noehammer, Regina Soldo, Peter Hettegger, Istvan Gyurjan, Ronald Kulovics, Silvia Schönthaler, Gabriel Beikircher, Albert Kriegner, Stephan Pabinger, Klemens Vierlinger A90 Rare disease diobanks for personalized medicine Ayşe Yüzbaşıoğlu, Meral Özgüç, Member of EuroBioBank - European Network of DNA, Cell and Tissue Banks for Rare Disease

Parental control options for child safety on the Internet

Bakalářská práce se zaměřuje na možnosti rodičovské kontroly bezpečnosti dětí na internetu a doporučení pro nastavení domácích pravidel používání internetu. V práci jsou analyzována rizika vznikající pro děti prostřednictvím internetu, popsána nastavení operačních systémů, speciálních aplikací, prohlížečů i jiných prostředků pro zajištění jejich ochrany a kontroly bezpečnosti. Dále je vytvořen seznam doporučení pro rodiče. Součástí práce jsou i webové stránky, které mají za cíl informovat rodiče o této problematice.ObhájenoThe bachelor thesis focuses on the possibilities of parental control of child safety on the Internet and recommendations for setting up the domestic rules of internet usage. The work analyzes risks arising for children through the Internet, describes the settings of operating systems, special applications, browsers and other means to ensure their protection and security control. Next, a list of recommendations for parents is created. The work also includes websites that aim to inform parents about this issue

The System of Use of Automated External Defibrillators by Units of the Fire Rescue Service of the Czech Republic

Import 02/11/2016Import 15/02/2016Diplomová práce se zabývá optimalizací používání automatizovaných externích defibrilátoru u jednotek Hasičského záchranného sboru České republiky a jednotek Sborů dobrovolných hasičů v jednotlivých krajích. Práce je rozdělena do 9 částí, kde je řešeno, jak lze zvýšit procento přežití osob postižených náhlou zástavou oběhu, používání defibrilátorů ve všech krajích ČR a systém používání. Dále je pak popsán systém vysílání jednotek a statistiky zásahů HZS Jihomoravského kraje. V závěru práce jsou shrnuty návrhy opatření, které by mohly zvýšit procenta úspěšnosti resuscitace s využití defibrilátorů do budoucna a tím přispět k zachránění většího počtu postižených osob. Práce je primárně určena pro potřeby Hasičského záchranného sboru, avšak lze ji využít i jako popularizačně-naučný materiál pro laickou veřejnost.Diploma thesis deals with optimizing the use of automated external defibrillators (AED) at units of Fire Rescue Service of Czech Republic and units of Voluntary Rescue Service in particular regions of Czech Republic. The Diploma thesis is divided into 9 parts, where is solved how to increase the survival rate of people affected by sudden cardiac arrest, using of defibrillators in all regions of the Czech Republic and the application system. Furthermore, it is described the system of dispatching the units and intervention statistics of Fire Rescue Service of the South Moravian region. The proposals for actions which could help to increase the success rate of resuscitation with using of AED to the future and thereby contribute to saving the larger number of people affected are summarized in the conclusion of the thesis. The work is primarily intended for the needs of FRS CR, however it can be used as a popularization-educational material for the general public.030 - Katedra požární ochranydobř