Estudio comparativo del desarrollo de la escritura cursiva en niños y niñas del 1er, 2do y 3er grado de primaria de un colegio estatal y uno privado del distrito de Surco

Se presenta el estudio comparativo del desarrollo de la escritura cursiva en niños y niñas del 1er, 2do y 3er grado de primaria de un colegio estatal y uno privado del distrito de Surco. El objetivo de la investigación fue identificar las diferencias en función al género, grado y tipo de gestión de la institución educativa que presentan los niños y niñas del 1er al 3er grado de primaria de un colegio estatal y uno privado del distrito de Surco del desarrollo de la escritura cursiva El tipo de investigación que se utilizo fue no experimental, descriptivo-transversal sobre una población total de 350 sujetos. Los resultados se obtuvieron a través de la Prueba exploratoria de escritura cursiva (P.E.E.C.) de Condemarín y Chadwick; la cual fue estandarizada para obtener resultados más certeros de la realidad peruana. Los resultados de esta investigación demostraron que no existen diferencias significativas en el desarrollo de la escritura cursiva entre los niños y niñas del 1er al 3er grado de un colegio estatal y uno privado en los subtest de velocidad normal y velocidad rápida de ejecución de la copia: sin embargo, en el sub test de calidad de la copia si se observó una diferencia significativa de desempeño a favor del colegio privado. La estandarización de la prueba PEEC ha demostrado su confiablidad y validez. Asimismo, se obtuvieron los baremos correspondientes para cada grado los cuales permiten estimar el desarrollo de la escritura cursiva en los niños del 1ro al 3er grado de primaria del distrito de Surco, contribuyendo de este modo, en la prevención de dificultades en la escritura.This thesis is a comparative study of the development of cursive writing in children from 1st, 2nd and 3rd grade of a public and a private school in the district of Surco. The aim of the research was to identify the differences in function of gender, grade and type of school management that 1st to 3rd grade children of a public school and a private from Surco distric have in the development of cursive writing. A non-experimental, cross-sectional descriptive method was used within a total population of 350 subjects. The Condemarín and Chadwick. Exploratory Cursive Writing Test (PEEC from its Spanish abbreviation) was applied to obtain the results. This Test was standardized in order to obtain accurate results for the Peruvian reality. The findings showed no significant differences in the development of cursive writing among children from 1st to 3rd grade of a public and a private school in the normal execution speed and fast speed of implementation writing subtests. A significant difference in performance in favor to the private school was found in quality of the copy writing speed subtest. PEEC Testing standardization results demonstrated statistic reliability and validity, as well as the corresponding scales for each grade which allow estimate the development of cursive writing in children from 1st to 3rd grade from Surco district, contributing in preventing writing difficulties .Tesi

“Aplicación de la evaluación técnico visual de las estructuras ante fenómenos naturales en el sector barrio de Selva Alegre desde la calle Ramón Gonzales artigas hasta la intersección de las calles Juan de Salinas y Antonio Checa”

Esta investigación presenta una evaluación técnica visual ante fenómenos naturales de las estructuras ubicadas en el sector del barrio de Selva Alegre específicamente a la zona comprendida entre las calles Ramón González Artigas, Francisco Guarderas, Antonio Checa y Juan de Salinas. De acuerdo a la Norma Ecuatoriana de la Construcción esta se encuentra definida como zona de peligro sísmico alto, es decir que la probabilidad de ocurrencia de sismos de magnitud importante es alta, de igual manera esta se encuentra amenazada también por los lahares que se producirían en caso de explotar el volcán Cotopaxi. En la primera parte de la investigación encontramos el marco teórico sobre el que se sustenta la evaluación de las construcciones, se definen los conceptos más importantes y relevantes como lo son los sismos y lahares, como se producen y cuáles son sus posibles efectos sobre las edificaciones. Luego se expone la metodología de investigación que se ha empleado, es decir se detalla cómo funcionan las fichas y se presenta el método probabilístico para la presentación de resultados. A continuación se presentan los resultados obtenidos de la evaluación y como paso final se tiene el capítulo de las conclusiones y recomendaciones que engloban a toda la investigación realizada

Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain)

<p>Abstract</p> <p>Background</p> <p>Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing. Dementia is one of the most significant public health problem. In recent years, the role of vascular risk factors (hypertension, diabetes mellitus and hypercholesterolemia) and depression has been evaluated.</p> <p>The incidence of dementia and risk factors has not been fully investigated in Spain. The aim of this study was to identify the risk factors for dementia, Alzheimer's disease (AD) and vascular dementia (VD) in elderly people in Munguialde County (Spain).</p> <p>Methods</p> <p>A two phase, door-to-door populational study was performed. Demographic variables and the presence of vascular risk factors and depression were recorded. The MMSE, the DSM-IV and the conventional criteria for AD and VD were used in the evaluation. The odds ratio for each risk factor was calculated by logistic regression analysis.</p> <p>Results</p> <p>1756 healthy subjects and 175 patients with dementia participated in the study. Of these, 133 had AD, 15 VD and the remainder other dementias. The risk factors for dementia and AD were female sex (OR = 1.67 and 1.97, respectively); age (OR = 1.14 and 1.15); stroke (OR = 7.84 and 3); and depression (OR = 53.08 and 3.19). Stroke was the only risk factor for VD (OR = 119).</p> <p>Conclusion</p> <p>Greater age, female sex, stroke and depression increase the risk of suffering dementia, AD and VD. The relationship between depression, vascular risk factors and dementia has clear public health implications. Prevention and early treatment of vascular risk factors and depression may have an important impact in lowering the risk of dementia and could modify the natural history of the disease.</p

Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain)

Es reproducción del documento publicado en http://dx.doi.org/10.1186/1471-2377-8-39Background: Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing. Dementia is one of the most significant public health problem. In recent years, the role of vascular risk factors (hypertension, diabetes mellitus and hypercholesterolemia) and depression has been evaluated. The incidence of dementia and risk factors has not been fully investigated in Spain. The aim of this study was to identify the risk factors for dementia, Alzheimer's disease (AD) and vascular dementia (VD) in elderly people in Munguialde County (Spain). Methods: A two phase, door-to-door populational study was performed. Demographic variables and the presence of vascular risk factors and depression were recorded. The MMSE, the DSM-IV and the conventional criteria for AD and VD were used in the evaluation. The odds ratio for each risk factor was calculated by logistic regression analysis. Results: 1756 healthy subjects and 175 patients with dementia participated in the study. Of these, 133 had AD, 15 VD and the remainder other dementias. The risk factors for dementia and AD were female sex (OR = 1.67 and 1.97, respectively); age (OR = 1.14 and 1.15); stroke (OR = 7.84 and 3); and depression (OR = 53.08 and 3.19). Stroke was the only risk factor for VD (OR = 119). Conclusion: Greater age, female sex, stroke and depression increase the risk of suffering dementia, AD and VD. The relationship between depression, vascular risk factors and dementia has clear public health implications. Prevention and early treatment of vascular risk factors and depression may have an important impact in lowering the risk of dementia and could modify the natural history of the disease.Fundación San Jose Etxealai; Fundación BB

Evaluación inicial de riesgos laborales por puestos de trabajo en la Universidad Adventista de Nicaragua UNADENIC localizada en la ciudad de Managua

El estudio presenta una propuesta inicial de riesgos laborales por puestos de trabajo dentro de las instalaciones de la universidad, en donde se analizará los factores de riesgo, causas y medidas preventivas necesarias; lo que beneficiará a los empleados y a la institución. A la vez se estará cumpliendo con las normativas establecidas por el INSS y el MITRAB. Dicha evaluación mejorara el ambiente de trabajo, lo que originara una disminución en los accidentes y enfermedades profesionales, además de reducir las pérdidas materiales y económicas; todo esto contribuye positivamente el desarrollo de la productividad de la institución

Effectiveness and safety of anti-CGRP monoclonal antibodies in patients over 65 years: a real-life multicentre analysis of 162 patients

Background Anti-CGRP monoclonal antibodies have shown notable effectiveness and tolerability in migraine patients; however, data on their use in elderly patients is still lacking, as clinical trials have implicit age restrictions and real-world evidence is scarce. In this study, we aimed to describe the safety and effectiveness of erenumab, galcanezumab and fremanezumab in migraine patients over 65 years old in real-life. Methods In this observational real-life study, a retrospective analysis of prospectively collected data from 18 different headache units in Spain was performed. Migraine patients who started treatment with any anti-CGRP monoclonal antibody after the age of 65 years were included. Primary endpoints were reduction in monthly migraine days after 6 months of treatment and the presence of adverse effects. Secondary endpoints were reductions in headache and medication intake frequencies by months 3 and 6, response rates, changes in patient-reported outcomes and reasons for discontinuation. As a subanalysis, reduction in monthly migraine days and proportion of adverse effects were also compared among the three monoclonal antibodies. Results A total of 162 patients were included, median age 68 years (range 65-87), 74.1% women. 42% had dyslipidaemia, 40.3% hypertension, 8% diabetes, and 6.2% previous cardiovascular ischaemic disease. The reduction in monthly migraine days at month 6 was 10.17.3 days. A total of 25.3% of patients presented adverse effects, all of them mild, with only two cases of blood pressure increase. Headache and medication intake frequencies were significantly reduced, and patient-reported outcomes were improved. The proportions of responders were 68%, 57%, 33% and 9% for reductions in monthly migraine days >= 30%,>= 50%,>= 75% and 100%, respectively. A total of 72.8% of patients continued with the treatment after 6 months. The reduction in migraine days was similar for the different anti-CGRP treatments, but fewer adverse effects were detected with fremanezumab (7.7%). Conclusions Anti-CGRP mAbs are safe and effective treatments in migraine patients over 65 years old in real-life clinical practice

The COMT Val158 Met polymorphism as an associated risk factor for Alzheimer disease and mild cognitive impairment in APOE 4 carriers

<p>Abstract</p> <p>Background</p> <p>The aim of this study is to examine the influence of the <it>catechol-O-methyltranferase (COMT) </it>gene (polymorphism Val158 Met) as a risk factor for Alzheimer's disease (AD) and mild cognitive impairment of amnesic type (MCI), and its synergistic effect with the <it>apolipoprotein E gene (APOE)</it>.</p> <p>A total of 223 MCI patients, 345 AD and 253 healthy controls were analyzed. Clinical criteria and neuropsychological tests were used to establish diagnostic groups.</p> <p>The DNA Bank of the University of the Basque Country (UPV-EHU) (Spain) determined <it>COMT </it>Val158 Met and <it>APOE </it>genotypes using real time polymerase chain reaction (rtPCR) and polymerase chain reaction (PCR), and restriction fragment length polymorphism (RFLPs), respectively. Multinomial logistic regression models were used to determine the risk of AD and MCI.</p> <p>Results</p> <p>Neither <it>COMT </it>alleles nor genotypes were independent risk factors for AD or MCI. The high activity genotypes (GG and AG) showed a synergistic effect with <it>APOE ε4 </it>allele, increasing the risk of AD (OR = 5.96, 95%CI 2.74-12.94, p < 0.001 and OR = 6.71, 95%CI 3.36-13.41, p < 0.001 respectivily). In AD patients this effect was greater in women.</p> <p>In MCI patients such as synergistic effect was only found between AG and <it>APOE ε4 </it>allele (OR = 3.21 95%CI 1.56-6.63, p = 0.02) and was greater in men (OR = 5.88 95%CI 1.69-20.42, p < 0.01).</p> <p>Conclusion</p> <p><it>COMT </it>(Val158 Met) polymorphism is not an independent risk factor for AD or MCI, but shows a synergistic effect with <it>APOE ε4 </it>allele that proves greater in women with AD.</p

Enfermedades crónicas

Adherencia al tratamiento farmacol&oacute;gico y relaci&oacute;n con el control metab&oacute;lico en pacientes con DM2Aluminio en pacientes con terapia de reemplazo renal cr&oacute;nico con hemodi&aacute;lisis en Bogot&aacute;, ColombiaAmputaci&oacute;n de extremidades inferiores: &iquest;est&aacute;n aumentando las tasas?Consumo de edulcorantes artificiales en j&oacute;venes universitariosC&oacute;mo crecen ni&ntilde;os normales de 2 a&ntilde;os que son sobrepeso a los 7 a&ntilde;osDiagn&oacute;stico con enfoque territorial de salud cardiovascular en la Regi&oacute;n MetropolitanaEfecto a corto plazo de una intervenci&oacute;n con ejercicio f&iacute;sico, en ni&ntilde;os con sobrepesoEfectos de la cirug&iacute;a bari&aacute;trica en pacientes con s&iacute;ndrome metab&oacute;lico e IMC &lt; 35 KG/M2Encuesta mundial de tabaquismo en estudiantes de profesiones de saludEnfermedades cr&oacute;nicas no transmisibles: Consecuencias sociales-sanitarias de comunidades rurales en ChileEpidemiolog&iacute;a de las muertes hospitalarias por patolog&iacute;as relacionadas a muerte encef&aacute;lica, Chile 2003-2007Estado nutricional y conductas alimentarias en adolescentes de 4&ordm; medio de la Regi&oacute;n de CoquimboEstudio de calidad de vida en una muestra del plan piloto para hepatitis CEvaluaci&oacute;n del proceso asistencial y de resultados de salud del GES de diabetes mellitus 2Factores de riesgo cardiovascular en poblaci&oacute;n universitaria de la Facsal, universidad de Tarapac&aacute;Implicancias psicosociales en la g&eacute;nesis, evoluci&oacute;n y tratamiento de pacientes con hipertensi&oacute;n arterial esencialInfarto agudo al miocardio (IAM): Realidad en el Hospital de Puerto Natales, 2009-2010Introducci&oacute;n de nuevas TIC y mejor&iacute;a de la asistencia a un programa de saludNi&ntilde;os obesos atendidos en el Cesfam de Puerto Natales y su entorno familiarPerfil de la mortalidad por c&aacute;ncer de cuello uterino en R&iacute;o de JaneiroPerfil del paciente primo-consultante del Programa de Salud Cardiovascular, Consultorio Cordillera Andina, Los AndesPrevalencia de automedicaci&oacute;n en mujeres beneficiarias del Hospital Comunitario de Til-TiPrevalencia de caries en poblaci&oacute;n preescolar y su relaci&oacute;n con malnutrici&oacute;n por excesoPrevalencia de retinopat&iacute;a diab&eacute;tica en comunas dependientes del Servicio de Salud Metropolitano Occidente (SSMOC)Problemas de adherencia farmacol&oacute;gica antihipertensiva en poblaci&oacute;n mapuche: Un estudio cualitativoRol biol&oacute;gico de los antioxidantes innatos en pacientes portadores de VIH/SidaSobrepeso en empleados de un restaurante de una universidad p&uacute;blica del estado de S&atilde;o Paul

Famílies botàniques de plantes medicinals

Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia, Assignatura: Botànica Farmacèutica, Curs: 2013-2014, Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són els recull de 175 treballs d’una família botànica d’interès medicinal realitzats de manera individual. Els treballs han estat realitzat per la totalitat dels estudiants dels grups M-2 i M-3 de l’assignatura Botànica Farmacèutica durant els mesos d’abril i maig del curs 2013-14. Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pel professor de l’assignatura i revisats i finalment co-avaluats entre els propis estudiants. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica